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The map label for this gene is htpX [H]

Identifier: 73542990

GI number: 73542990

Start: 3616666

End: 3617544

Strand: Direct

Name: htpX [H]

Synonym: Reut_A3307

Alternate gene names: 73542990

Gene position: 3616666-3617544 (Clockwise)

Preceding gene: 73542989

Following gene: 73542991

Centisome position: 95.01

GC content: 63.71

Gene sequence:

>879_bases
ATGAAACGCGTCCTGCTTTTCCTGGCGACCAACCTCGCCGTCATGCTTGTCCTCAGCATCACCGCCAGCGTCCTTGGCGT
GAACCGCTTCCTGACCGCCAACGGTCTCAACTTCGGCATGCTGCTCGCTTTTGCCGCGCTGATGGGCTTCGGCGGCGCCT
TCATTTCGCTGCTGATGTCCAAAACCATTGCCAAGTGGTCCACCAGTGCGCAGGTCATCACGCACCCGAGCACAAGCACC
GAACTGTGGCTGGTGCAGACCGTGCAGAAGCTGTCGCAGAAGGCCGGGTTGCCCATGCCGGAAGTGGCGATCTACGAGGG
CGAGCCCAACGCGTTCGCGACGGGCGCGACGAAGAACAGCTCGCTGGTCGCCGTTTCGACTGGCCTGCTGCAGTCGATGT
CGCATGACGAGGTGGAAGCCGTGCTGGCGCACGAAGTGGCGCACATCGCCAATGGCGACATGGTCACGCTCACGCTGATC
CAGGGCGTCGTCAACACGTTCGTGATCTTCCTTGCGCGCGTGGTCGGCTATTTCGTCGATTCGATGCTGCGCAAGAACGA
CGAGGAGTCGAGCGGGCCCGGCATTGGCTACATGGTCACGGTGATCGTCTGCGAAATCGTCTTCGGCGTGCTGGCCAGCA
TCATCGTGGCCGCCTTCTCGCGCCGTCGCGAGTTCCGTGCCGACGCCGGTGCGGCGAGCCTGATGGGCTCGTCCACGCCG
ATGGTGGGCGCATTGCGCCGCCTCGGCGGACTGGATGCCGACGGGTTGCCGCAGAACATGCAGGCCATGGGCATAGCAGG
TGGAAAGTCGTGGATGGAGCTGTTCTCGAGCCATCCGCCGATCGAGCAGCGCATTGCGGCGCTGCAGTCGGCACGCTGA

Upstream 100 bases:

>100_bases
GGCAATCGTCGCGCATGACCGTTCCTGCGTGCAGTGCCGTTGAAGCGCCGCGCGCGCCTGCGGCTCGTCCGCGTCTTTCC
TGCTGTCTTGTTCCACACTC

Downstream 100 bases:

>100_bases
AGCCGATCCATCGCTGCGACCCGCGCCGGGGCCTCGGCGGCCCGGGCGGTGTCGCAGGCATCCTGTCAGGGAGCAAGAGA
TGCAAGCGAACCTGTTGGAC

Product: heat shock protein HtpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MKRVLLFLATNLAVMLVLSITASVLGVNRFLTANGLNFGMLLAFAALMGFGGAFISLLMSKTIAKWSTSAQVITHPSTST
ELWLVQTVQKLSQKAGLPMPEVAIYEGEPNAFATGATKNSSLVAVSTGLLQSMSHDEVEAVLAHEVAHIANGDMVTLTLI
QGVVNTFVIFLARVVGYFVDSMLRKNDEESSGPGIGYMVTVIVCEIVFGVLASIIVAAFSRRREFRADAGAASLMGSSTP
MVGALRRLGGLDADGLPQNMQAMGIAGGKSWMELFSSHPPIEQRIAALQSAR

Sequences:

>Translated_292_residues
MKRVLLFLATNLAVMLVLSITASVLGVNRFLTANGLNFGMLLAFAALMGFGGAFISLLMSKTIAKWSTSAQVITHPSTST
ELWLVQTVQKLSQKAGLPMPEVAIYEGEPNAFATGATKNSSLVAVSTGLLQSMSHDEVEAVLAHEVAHIANGDMVTLTLI
QGVVNTFVIFLARVVGYFVDSMLRKNDEESSGPGIGYMVTVIVCEIVFGVLASIIVAAFSRRREFRADAGAASLMGSSTP
MVGALRRLGGLDADGLPQNMQAMGIAGGKSWMELFSSHPPIEQRIAALQSAR
>Mature_292_residues
MKRVLLFLATNLAVMLVLSITASVLGVNRFLTANGLNFGMLLAFAALMGFGGAFISLLMSKTIAKWSTSAQVITHPSTST
ELWLVQTVQKLSQKAGLPMPEVAIYEGEPNAFATGATKNSSLVAVSTGLLQSMSHDEVEAVLAHEVAHIANGDMVTLTLI
QGVVNTFVIFLARVVGYFVDSMLRKNDEESSGPGIGYMVTVIVCEIVFGVLASIIVAAFSRRREFRADAGAASLMGSSTP
MVGALRRLGGLDADGLPQNMQAMGIAGGKSWMELFSSHPPIEQRIAALQSAR

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=295, Percent_Identity=50.5084745762712, Blast_Score=259, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6322577, Length=235, Percent_Identity=25.9574468085106, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30952; Mature: 30952

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRVLLFLATNLAVMLVLSITASVLGVNRFLTANGLNFGMLLAFAALMGFGGAFISLLMS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHH
KTIAKWSTSAQVITHPSTSTELWLVQTVQKLSQKAGLPMPEVAIYEGEPNAFATGATKNS
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCCC
SLVAVSTGLLQSMSHDEVEAVLAHEVAHIANGDMVTLTLIQGVVNTFVIFLARVVGYFVD
CEEEEHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLRKNDEESSGPGIGYMVTVIVCEIVFGVLASIIVAAFSRRREFRADAGAASLMGSSTP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCH
MVGALRRLGGLDADGLPQNMQAMGIAGGKSWMELFSSHPPIEQRIAALQSAR
HHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MKRVLLFLATNLAVMLVLSITASVLGVNRFLTANGLNFGMLLAFAALMGFGGAFISLLMS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHH
KTIAKWSTSAQVITHPSTSTELWLVQTVQKLSQKAGLPMPEVAIYEGEPNAFATGATKNS
HHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEECCCCCCC
SLVAVSTGLLQSMSHDEVEAVLAHEVAHIANGDMVTLTLIQGVVNTFVIFLARVVGYFVD
CEEEEHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SMLRKNDEESSGPGIGYMVTVIVCEIVFGVLASIIVAAFSRRREFRADAGAASLMGSSTP
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCH
MVGALRRLGGLDADGLPQNMQAMGIAGGKSWMELFSSHPPIEQRIAALQSAR
HHHHHHHHCCCCCCCCCCCHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA