Click here to switch to the map view.

The map label for this gene is mtnN [H]

Identifier: 73542725

GI number: 73542725

Start: 3345760

End: 3346527

Strand: Direct

Name: mtnN [H]

Synonym: Reut_A3041

Alternate gene names: 73542725

Gene position: 3345760-3346527 (Clockwise)

Preceding gene: 73542721

Following gene: 161611253

Centisome position: 87.9

GC content: 68.1

Gene sequence:

>768_bases
ATGACCCTCGGCATCCTCGCCGCCCTGCATGACGAAGTCGACAGCCTGGTCGCTGCCATGCGCCATGAAGACGCCCGCGC
GGCCATCCACCGCATCGGCATGCGCGATTATCACGTGGGCCATCTGCACGGACAGCCGTGCGTGCTCGTGCTTGCCCGCG
TCGGCAAGGTCGCCGCAGCCGCGACCACGGCCACGCTGATCCGCGAATTCGGCGTGCAGGAGGTCGTCTTTACCGGCCTG
GCCGGCGGCGTCGGCGACGGCGTGCGCGTCGGCGATATCGTGATCGCCAGCGAAACCATGCAGCACGACATGGACGCGCG
TCCGCTGTTCCCGCGCCATGAAATACCGCTGCTGGACTGCGTGCGCTTTCCCGCCGATCCCACCCTGACCGAAGCGCTGC
GCGCGGCGGCCAACCGGTTCCTGCGCGACGACCTGCCGACCGATGTGCCGCCAGGGGTGCGCGAACACTTCGGCATCGGC
ACGCCGGCGCTGCAGCTTGGGCTCGTCGCCAGTGGCGACCAGTTCATCAACTCGGCCGTGGCCGTCGCGGAACTGCGCGA
ACGCCTGCCGGGACTGATGGCCGTGGAAATGGAAGGGGCCGCCGTCGCGCAGGTCTGCCATGAATACGGCGTGCGCTACG
CGGTCATGCGGACTATCTCCGACCGCGCCGACGACAGTGCGCATGTGGATTTCCCTGCATTTCTGAAGCAGGTCGCCAGC
CACTATTCGGATGGCATCCTGCGGCGGTTCCTGGCCGCGCGCGCTTGA

Upstream 100 bases:

>100_bases
AAAGCGCAGCCAGCGCCGCACGTGGAAAGGATCAAGGCGGCCTATGAGGGCCCGGCGTGCGCCGGTATGCTTTGGCTTTT
CGCTTCCAGCACGCCCCCCC

Downstream 100 bases:

>100_bases
CCACCATCAAACGCGGCTGCCGATTCCTGCGCGATCGTCAGTTCTGAAGTTATCCGTGGCGGGGCCGCAACGCGCCCCAC
ACGCCGACCAGCAGCGCGGC

Product: 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 255; Mature: 254

Protein sequence:

>255_residues
MTLGILAALHDEVDSLVAAMRHEDARAAIHRIGMRDYHVGHLHGQPCVLVLARVGKVAAAATTATLIREFGVQEVVFTGL
AGGVGDGVRVGDIVIASETMQHDMDARPLFPRHEIPLLDCVRFPADPTLTEALRAAANRFLRDDLPTDVPPGVREHFGIG
TPALQLGLVASGDQFINSAVAVAELRERLPGLMAVEMEGAAVAQVCHEYGVRYAVMRTISDRADDSAHVDFPAFLKQVAS
HYSDGILRRFLAARA

Sequences:

>Translated_255_residues
MTLGILAALHDEVDSLVAAMRHEDARAAIHRIGMRDYHVGHLHGQPCVLVLARVGKVAAAATTATLIREFGVQEVVFTGL
AGGVGDGVRVGDIVIASETMQHDMDARPLFPRHEIPLLDCVRFPADPTLTEALRAAANRFLRDDLPTDVPPGVREHFGIG
TPALQLGLVASGDQFINSAVAVAELRERLPGLMAVEMEGAAVAQVCHEYGVRYAVMRTISDRADDSAHVDFPAFLKQVAS
HYSDGILRRFLAARA
>Mature_254_residues
TLGILAALHDEVDSLVAAMRHEDARAAIHRIGMRDYHVGHLHGQPCVLVLARVGKVAAAATTATLIREFGVQEVVFTGLA
GGVGDGVRVGDIVIASETMQHDMDARPLFPRHEIPLLDCVRFPADPTLTEALRAAANRFLRDDLPTDVPPGVREHFGIGT
PALQLGLVASGDQFINSAVAVAELRERLPGLMAVEMEGAAVAQVCHEYGVRYAVMRTISDRADDSAHVDFPAFLKQVASH
YSDGILRRFLAARA

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=243, Percent_Identity=31.2757201646091, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 27454; Mature: 27323

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGILAALHDEVDSLVAAMRHEDARAAIHRIGMRDYHVGHLHGQPCVLVLARVGKVAAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHH
ATTATLIREFGVQEVVFTGLAGGVGDGVRVGDIVIASETMQHDMDARPLFPRHEIPLLDC
HHHHHHHHHHCHHHHHHHHHCCCCCCCCEECCEEEEHHHHHHCCCCCCCCCCCCCCHHHH
VRFPADPTLTEALRAAANRFLRDDLPTDVPPGVREHFGIGTPALQLGLVASGDQFINSAV
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHCEECCCHHHHHHHH
AVAELRERLPGLMAVEMEGAAVAQVCHEYGVRYAVMRTISDRADDSAHVDFPAFLKQVAS
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
HYSDGILRRFLAARA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLGILAALHDEVDSLVAAMRHEDARAAIHRIGMRDYHVGHLHGQPCVLVLARVGKVAAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHH
ATTATLIREFGVQEVVFTGLAGGVGDGVRVGDIVIASETMQHDMDARPLFPRHEIPLLDC
HHHHHHHHHHCHHHHHHHHHCCCCCCCCEECCEEEEHHHHHHCCCCCCCCCCCCCCHHHH
VRFPADPTLTEALRAAANRFLRDDLPTDVPPGVREHFGIGTPALQLGLVASGDQFINSAV
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHCEECCCHHHHHHHH
AVAELRERLPGLMAVEMEGAAVAQVCHEYGVRYAVMRTISDRADDSAHVDFPAFLKQVAS
HHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
HYSDGILRRFLAARA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA