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The map label for this gene is engD [H]

Identifier: 73542721

GI number: 73542721

Start: 3341751

End: 3342914

Strand: Direct

Name: engD [H]

Synonym: Reut_A3037

Alternate gene names: 73542721

Gene position: 3341751-3342914 (Clockwise)

Preceding gene: 73542715

Following gene: 73542725

Centisome position: 87.79

GC content: 63.83

Gene sequence:

>1164_bases
ATGGCGCGGCGGGGCAAGGCCGAGAGCCCCCATCCGCTAGAATATGGGTTTTGCTATTTCCCGCCTGACACCATGAGCCT
CCAATGCGGCATCGTCGGCCTGCCGAACGTCGGCAAGTCCACGCTGTTCAATGCCCTGACCAAGGCCGGCATCGCCGCCG
AAAACTATCCGTTCTGCACCATCGAACCCAATGTGGGCGTGGTCGAAGTGCCGGATCCGAGGCTCGCCAAGCTGGCCGAG
ATCGTCAAACCGGAGCGCATCCTGCCGGCCACGGTCGAGTTTGTCGACATCGCCGGCCTGGTGGCGGGCGCTTCCAAAGG
GGAAGGCCTGGGCAACCAGTTCCTTGCCAACATCCGGGAATGCGACGCCATCACCCACGTGGTGCGCTGCTTCGAAGACG
AGAACGTGATCCACGTGGCCGGCCGGGTCGATCCGCTGTCGGACATTGAAGTGATCAACACCGAACTGGCGCTGGCCGAC
CTGGGCACAGTCGAGAAGGCGCTGGCCCGCTATATCAAGCCCGCCCGCGCCGGCGACAAGGAAGCCCAGCGTCTGGTCGC
CGTGCTGGAAAAGGCACAAGCCGTGCTCGACCAGGCCAAGGCCGTGCGCACGCTCGACCTCGCGCCGGAAGAGTGGGATG
CGATCCGCCCGTTCTGCCTGATCACCGCCAAGCCGACAATGTATGTCGCCAACGTGCGTGAAGACGGTTTCGAGAACAAC
CCGCACCTGGACGCCGTGCGCGAGTACGCCAAGCAGACCAATTCCCCGGTCGTGGCCGTCTGCGCCGCCATCGAAGCGGA
GATCGCCGACCTGGACGACGCCGACAAGGCCGAATTCCTGGCCGACCTCGGCATGGAAGAGCCTGGCCTGGACCGCGTGA
TCCGCGCCGGCTTCAAGCTGCTGGGCCTGCAGACCTACTTCACGGCAGGCGTGAAGGAAGTTCGCGCCTGGACCATCCAC
GTGGGCGACACGGCGCCGAAGGCTGCCGGCGTCATCCACACCGACTTCGAACGCGGCTTCATCCGCGCGCAGACGATTTC
CTATGACGACTACATCGCCTTCAAGGGCGAGACTGGCGCGAAGGAAGCCGGCAAGATGCGGGCGGAAGGCAAGGAGTATG
TGGTGAAGGATGGGGATGTGTTGAATTTCTTGTTCAACGTCTGA

Upstream 100 bases:

>100_bases
CGACAACGGCGATCTGGAAAGCTGAGGAATTGCGGATGGACGCGTTGGATCGGGTCATGGCTGGATTATAGCCACCTCAC
CCGCGCGGCCCCGGCGGCTC

Downstream 100 bases:

>100_bases
TCTGCATCCCGCCCCAGTCGAGAAAGCCCGCAATCGCGGGCTTTCTTGCTTTCCGGGATCGGGAGAATCTACAGCTCTTC
CATCCGCTCCCCTCTCAACC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MARRGKAESPHPLEYGFCYFPPDTMSLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGVVEVPDPRLAKLAE
IVKPERILPATVEFVDIAGLVAGASKGEGLGNQFLANIRECDAITHVVRCFEDENVIHVAGRVDPLSDIEVINTELALAD
LGTVEKALARYIKPARAGDKEAQRLVAVLEKAQAVLDQAKAVRTLDLAPEEWDAIRPFCLITAKPTMYVANVREDGFENN
PHLDAVREYAKQTNSPVVAVCAAIEAEIADLDDADKAEFLADLGMEEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIH
VGDTAPKAAGVIHTDFERGFIRAQTISYDDYIAFKGETGAKEAGKMRAEGKEYVVKDGDVLNFLFNV

Sequences:

>Translated_387_residues
MARRGKAESPHPLEYGFCYFPPDTMSLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGVVEVPDPRLAKLAE
IVKPERILPATVEFVDIAGLVAGASKGEGLGNQFLANIRECDAITHVVRCFEDENVIHVAGRVDPLSDIEVINTELALAD
LGTVEKALARYIKPARAGDKEAQRLVAVLEKAQAVLDQAKAVRTLDLAPEEWDAIRPFCLITAKPTMYVANVREDGFENN
PHLDAVREYAKQTNSPVVAVCAAIEAEIADLDDADKAEFLADLGMEEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIH
VGDTAPKAAGVIHTDFERGFIRAQTISYDDYIAFKGETGAKEAGKMRAEGKEYVVKDGDVLNFLFNV
>Mature_386_residues
ARRGKAESPHPLEYGFCYFPPDTMSLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCTIEPNVGVVEVPDPRLAKLAEI
VKPERILPATVEFVDIAGLVAGASKGEGLGNQFLANIRECDAITHVVRCFEDENVIHVAGRVDPLSDIEVINTELALADL
GTVEKALARYIKPARAGDKEAQRLVAVLEKAQAVLDQAKAVRTLDLAPEEWDAIRPFCLITAKPTMYVANVREDGFENNP
HLDAVREYAKQTNSPVVAVCAAIEAEIADLDDADKAEFLADLGMEEPGLDRVIRAGFKLLGLQTYFTAGVKEVRAWTIHV
GDTAPKAAGVIHTDFERGFIRAQTISYDDYIAFKGETGAKEAGKMRAEGKEYVVKDGDVLNFLFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=42.8184281842818, Blast_Score=296, Evalue=2e-80,
Organism=Homo sapiens, GI58761502, Length=218, Percent_Identity=36.2385321100917, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1787454, Length=363, Percent_Identity=71.900826446281, Blast_Score=537, Evalue=1e-154,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=30.7086614173228, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=41.2568306010929, Blast_Score=283, Evalue=8e-77,
Organism=Caenorhabditis elegans, GI17552324, Length=197, Percent_Identity=26.9035532994924, Blast_Score=66, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=40, Blast_Score=249, Evalue=5e-67,
Organism=Saccharomyces cerevisiae, GI6321773, Length=383, Percent_Identity=33.420365535248, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6321649, Length=207, Percent_Identity=34.7826086956522, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24640873, Length=368, Percent_Identity=41.8478260869565, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24640877, Length=368, Percent_Identity=41.8478260869565, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24640875, Length=368, Percent_Identity=41.8478260869565, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24640879, Length=326, Percent_Identity=39.2638036809816, Blast_Score=234, Evalue=9e-62,
Organism=Drosophila melanogaster, GI24585318, Length=137, Percent_Identity=32.1167883211679, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 42047; Mature: 41916

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRGKAESPHPLEYGFCYFPPDTMSLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCT
CCCCCCCCCCCCCCCEEEECCCCCCEEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEE
IEPNVGVVEVPDPRLAKLAEIVKPERILPATVEFVDIAGLVAGASKGEGLGNQFLANIRE
ECCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
CDAITHVVRCFEDENVIHVAGRVDPLSDIEVINTELALADLGTVEKALARYIKPARAGDK
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EAQRLVAVLEKAQAVLDQAKAVRTLDLAPEEWDAIRPFCLITAKPTMYVANVREDGFENN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEECCCEEEEECHHCCCCCC
PHLDAVREYAKQTNSPVVAVCAAIEAEIADLDDADKAEFLADLGMEEPGLDRVIRAGFKL
CCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
LGLQTYFTAGVKEVRAWTIHVGDTAPKAAGVIHTDFERGFIRAQTISYDDYIAFKGETGA
HHHHHHHHHHHHEEEEEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCEEEECCCCCC
KEAGKMRAEGKEYVVKDGDVLNFLFNV
HHHHHHHCCCCEEEEECCCHHHHHHCC
>Mature Secondary Structure 
ARRGKAESPHPLEYGFCYFPPDTMSLQCGIVGLPNVGKSTLFNALTKAGIAAENYPFCT
CCCCCCCCCCCCCCEEEECCCCCCEEEECEEECCCCCHHHHHHHHHHHCCCCCCCCEEE
IEPNVGVVEVPDPRLAKLAEIVKPERILPATVEFVDIAGLVAGASKGEGLGNQFLANIRE
ECCCCCEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
CDAITHVVRCFEDENVIHVAGRVDPLSDIEVINTELALADLGTVEKALARYIKPARAGDK
HHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
EAQRLVAVLEKAQAVLDQAKAVRTLDLAPEEWDAIRPFCLITAKPTMYVANVREDGFENN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCEEEEEECCCEEEEECHHCCCCCC
PHLDAVREYAKQTNSPVVAVCAAIEAEIADLDDADKAEFLADLGMEEPGLDRVIRAGFKL
CCHHHHHHHHHHCCCCCEEEHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHH
LGLQTYFTAGVKEVRAWTIHVGDTAPKAAGVIHTDFERGFIRAQTISYDDYIAFKGETGA
HHHHHHHHHHHHEEEEEEEEECCCCCCCCCEEEECCCCCEEEEEEECCCCEEEECCCCCC
KEAGKMRAEGKEYVVKDGDVLNFLFNV
HHHHHHHCCCCEEEEECCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]