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The map label for this gene is dsdA

Identifier: 73542599

GI number: 73542599

Start: 3190183

End: 3191514

Strand: Direct

Name: dsdA

Synonym: Reut_A2915

Alternate gene names: 73542599

Gene position: 3190183-3191514 (Clockwise)

Preceding gene: 73542597

Following gene: 73542600

Centisome position: 83.81

GC content: 64.94

Gene sequence:

>1332_bases
ATGGTCACCCTGTCCCTCACGCCCGAGCTATTAGCAAAACTTCAATCTAGACAACCGCTGCTTTGGGTGAATCCGAGGTT
GGGACAACCGCTGCCGGCTTCCGCCCCATCCTTGGAACTGATCGCAGCGGCAGAAGCGCGTCTTGCACGCTGCGCCCCGC
TTATGGCGGCGCTGTTTCCCGAACTGGCGTCCAGCCATGGGCAAGTGGAATCGCAATTGATGCCAGCCACCGGCCTCCAA
TACGCGCTCGGCGAAGGCGCCGAGGGCGCGTGGTTCATCAAGCGTGACGACCAACTCCCGACTGCTGGTTCTATCAAGGC
ACGCGGCGGCTTTCATGAAGTGCTGGCGATTGCTGAATCCATCGCGATCGAACACGGCATGCTCGACCCGGATGGTGATC
GCCGCGTGCTCGCAACAGAGGCGGCGCGCAAGCTGTTCTCGCAATACTCGGTGACGGTCGGCAGCACCGGCAACCTCGGC
CTGAGCATCGGCGTGATGGCGGCGGCGCTCGGATTCGATGCGGTGGTGCATATGTCCGCGGACGCCAAGGCGTGGAAGAA
GGACCGCCTGCGCAAGCGCGGCGTGCGCGTCGTGGAGCATGAAGGCGACTACGCGCAAGCCGTGGCAGCGGGCCGCGAAC
AGGCATTGGGCGCGACACGCTGCCATTTTGTCGATGACGAGCGCTCCGCCCTGCTTTTCTTCGGATATGCCGCCGCGGCA
CGTCATCTGGCGCGCCAACTGGCCGAAGCCGGCCGCGTAGTGGATGCCGCGCATCCGCTCTTCGTCTATCTCCCGTGCGG
GGTCGGCGGCGCGCCCGGTGGCATCACGTATGGGCTCAAGGCACTGTTAGGCGACCACGTGCATTGCTTCTTTGCCGAGC
CCGTGGCCTCGCCGTGCGTACTGGTGCAGTTGGCCTCCGGCTCGGATGATCCCGTATCCGTCTACGACATCGGCCTCGAC
AACCGGACCGATGCTGATGGCCTCGCCGTCGGCCAGGCATCCCATCTGGTCAGCCCGCTGATGGCTTCCCAACTCGCCGG
CGTGTTCACGGTCCCCGACGATCAGCTCTATGTTCAGTTGCTCGCGCTCAAGACGTCGATGGGTGTGGAAGTCGAACCCT
CAGCGGCGGCCGGCATCGGCGGCCCGGGCTGGTTGCGCGACTCCCCCGAAGGCCGAGCGTATGTGCGCGATCACGGGCTC
GACATGCGCGACGCGACGCATGTGATCTGGGCTACCGGCGGCTCGCTCGTTCCGCGAGAAGAGCTTCACCGGTTTCAGGC
TTACGCGACCGCACTGGCCCATGTGCCTGGGGCGATGCATAAGGCAGCCTGA

Upstream 100 bases:

>100_bases
ATTAGCCTGACTAATGCATGCGTTAGAAACGATCGCTATTCTTGCACGGCTGCGGCCCTTACGATCGCTTTCAGTAAGGA
CTTTTCTGGAGAATGACCTG

Downstream 100 bases:

>100_bases
CGCTCTCGATCCCAGTGTTTTCCGTGATCGCCTCACCGGCGTCATGTGCGCACTATCCTGAAATGGAGGGAACGCCGGAC
AGGAAATCGGGACGGGTTGC

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MVTLSLTPELLAKLQSRQPLLWVNPRLGQPLPASAPSLELIAAAEARLARCAPLMAALFPELASSHGQVESQLMPATGLQ
YALGEGAEGAWFIKRDDQLPTAGSIKARGGFHEVLAIAESIAIEHGMLDPDGDRRVLATEAARKLFSQYSVTVGSTGNLG
LSIGVMAAALGFDAVVHMSADAKAWKKDRLRKRGVRVVEHEGDYAQAVAAGREQALGATRCHFVDDERSALLFFGYAAAA
RHLARQLAEAGRVVDAAHPLFVYLPCGVGGAPGGITYGLKALLGDHVHCFFAEPVASPCVLVQLASGSDDPVSVYDIGLD
NRTDADGLAVGQASHLVSPLMASQLAGVFTVPDDQLYVQLLALKTSMGVEVEPSAAAGIGGPGWLRDSPEGRAYVRDHGL
DMRDATHVIWATGGSLVPREELHRFQAYATALAHVPGAMHKAA

Sequences:

>Translated_443_residues
MVTLSLTPELLAKLQSRQPLLWVNPRLGQPLPASAPSLELIAAAEARLARCAPLMAALFPELASSHGQVESQLMPATGLQ
YALGEGAEGAWFIKRDDQLPTAGSIKARGGFHEVLAIAESIAIEHGMLDPDGDRRVLATEAARKLFSQYSVTVGSTGNLG
LSIGVMAAALGFDAVVHMSADAKAWKKDRLRKRGVRVVEHEGDYAQAVAAGREQALGATRCHFVDDERSALLFFGYAAAA
RHLARQLAEAGRVVDAAHPLFVYLPCGVGGAPGGITYGLKALLGDHVHCFFAEPVASPCVLVQLASGSDDPVSVYDIGLD
NRTDADGLAVGQASHLVSPLMASQLAGVFTVPDDQLYVQLLALKTSMGVEVEPSAAAGIGGPGWLRDSPEGRAYVRDHGL
DMRDATHVIWATGGSLVPREELHRFQAYATALAHVPGAMHKAA
>Mature_443_residues
MVTLSLTPELLAKLQSRQPLLWVNPRLGQPLPASAPSLELIAAAEARLARCAPLMAALFPELASSHGQVESQLMPATGLQ
YALGEGAEGAWFIKRDDQLPTAGSIKARGGFHEVLAIAESIAIEHGMLDPDGDRRVLATEAARKLFSQYSVTVGSTGNLG
LSIGVMAAALGFDAVVHMSADAKAWKKDRLRKRGVRVVEHEGDYAQAVAAGREQALGATRCHFVDDERSALLFFGYAAAA
RHLARQLAEAGRVVDAAHPLFVYLPCGVGGAPGGITYGLKALLGDHVHCFFAEPVASPCVLVQLASGSDDPVSVYDIGLD
NRTDADGLAVGQASHLVSPLMASQLAGVFTVPDDQLYVQLLALKTSMGVEVEPSAAAGIGGPGWLRDSPEGRAYVRDHGL
DMRDATHVIWATGGSLVPREELHRFQAYATALAHVPGAMHKAA

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=428, Percent_Identity=47.8971962616822, Blast_Score=369, Evalue=1e-103,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_CUPPJ (Q46X58)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_297119.1
- ProteinModelPortal:   Q46X58
- SMR:   Q46X58
- GeneID:   3610457
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A2915
- NMPDR:   fig|264198.3.peg.2697
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- ProtClustDB:   PRK02991
- BioCyc:   REUT264198:REUT_A2915-MONOMER
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 46705; Mature: 46705

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLSLTPELLAKLQSRQPLLWVNPRLGQPLPASAPSLELIAAAEARLARCAPLMAALFP
CEEEECCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELASSHGQVESQLMPATGLQYALGEGAEGAWFIKRDDQLPTAGSIKARGGFHEVLAIAES
HHHHCCCCHHHHCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
IAIEHGMLDPDGDRRVLATEAARKLFSQYSVTVGSTGNLGLSIGVMAAALGFDAVVHMSA
HHHHCCCCCCCCCCEEHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHEEEECC
DAKAWKKDRLRKRGVRVVEHEGDYAQAVAAGREQALGATRCHFVDDERSALLFFGYAAAA
CHHHHHHHHHHHCCCEEEECCCCHHHHHHHCHHHHCCCCEEEEECCCCCEEEEEHHHHHH
RHLARQLAEAGRVVDAAHPLFVYLPCGVGGAPGGITYGLKALLGDHVHCFFAEPVASPCV
HHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEE
LVQLASGSDDPVSVYDIGLDNRTDADGLAVGQASHLVSPLMASQLAGVFTVPDDQLYVQL
EEEEECCCCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHCCEEECCCHHHHHHH
LALKTSMGVEVEPSAAAGIGGPGWLRDSPEGRAYVRDHGLDMRDATHVIWATGGSLVPRE
HHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHH
ELHRFQAYATALAHVPGAMHKAA
HHHHHHHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MVTLSLTPELLAKLQSRQPLLWVNPRLGQPLPASAPSLELIAAAEARLARCAPLMAALFP
CEEEECCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ELASSHGQVESQLMPATGLQYALGEGAEGAWFIKRDDQLPTAGSIKARGGFHEVLAIAES
HHHHCCCCHHHHCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHH
IAIEHGMLDPDGDRRVLATEAARKLFSQYSVTVGSTGNLGLSIGVMAAALGFDAVVHMSA
HHHHCCCCCCCCCCEEHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHEEEECC
DAKAWKKDRLRKRGVRVVEHEGDYAQAVAAGREQALGATRCHFVDDERSALLFFGYAAAA
CHHHHHHHHHHHCCCEEEECCCCHHHHHHHCHHHHCCCCEEEEECCCCCEEEEEHHHHHH
RHLARQLAEAGRVVDAAHPLFVYLPCGVGGAPGGITYGLKALLGDHVHCFFAEPVASPCV
HHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCCEE
LVQLASGSDDPVSVYDIGLDNRTDADGLAVGQASHLVSPLMASQLAGVFTVPDDQLYVQL
EEEEECCCCCCEEEEEECCCCCCCCCCEEECCHHHHHHHHHHHHHCCEEECCCHHHHHHH
LALKTSMGVEVEPSAAAGIGGPGWLRDSPEGRAYVRDHGLDMRDATHVIWATGGSLVPRE
HHHHHCCCCEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCHH
ELHRFQAYATALAHVPGAMHKAA
HHHHHHHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA