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The map label for this gene is wrbA [H]

Identifier: 73542588

GI number: 73542588

Start: 3180533

End: 3181093

Strand: Direct

Name: wrbA [H]

Synonym: Reut_A2904

Alternate gene names: 73542588

Gene position: 3180533-3181093 (Clockwise)

Preceding gene: 73542587

Following gene: 73542589

Centisome position: 83.55

GC content: 63.64

Gene sequence:

>561_bases
ATGAAGAAGCTAGCCATCATCTATCACAGCGCCCACGGCCACACCAGGCACATTGCGTCCTGTGTGCGCCAGGGCGCCGC
GAGTGTCGCCGATACCGAGGCGCAATTGCTGAATGCGGAGGACCTTGCCGGAGCGCCCGACACACTGCTTGGCTATGACG
CCTACATTCTAGGCTCGCCCACCTATCTCGGCGGCGTCTCCGGTCCCTTCAAGTCTTTCATGGACGCCACCGGCCGCTTG
TGGCGAACGCAGCAGCTCAAGGGCAAGCTAGCGGCCGGCTTCACGGTGTCGTCGCTGCCCGCGGGCGACAAGCAATCCAC
GCTGATGTCGATGTTCGTGTTCTGCATGCAGCACGGCATGCTGTGGGTCGGCAATCCGATCCTGCCGGAGCAGCATGCCG
GTGTCCCTTACGACGACGCCGCCAACCGGCTCGGATCATGGTCGGGCCTGATGGCACAGTCCGATCACTCCGCGCCGGCG
GACGGATTCGGTGCGGGAGATGTGAAGACCGCCCGGATGTTCGGCAGGAACTTCGCGGAAACGCTGCACCGCATCCTTTG
A

Upstream 100 bases:

>100_bases
TCGGATTCGGCCTGTACCTCTCAGCGCTCGTTGTCGCATGTATCGGGCAATGAACGGTGCTTGCTTCGATCGACGCATAA
CGCCACCTGGAAACCACATC

Downstream 100 bases:

>100_bases
CCATGTCCAGTAAATGGAACCGCGAGGTACTCAGATGATCCCCAGCAAATACGCGCCGCAGTTGTTCAGTCTCGTGCTGT
CAGGACTCATGTCCCTGATT

Product: NADPH-dependent FMN reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MKKLAIIYHSAHGHTRHIASCVRQGAASVADTEAQLLNAEDLAGAPDTLLGYDAYILGSPTYLGGVSGPFKSFMDATGRL
WRTQQLKGKLAAGFTVSSLPAGDKQSTLMSMFVFCMQHGMLWVGNPILPEQHAGVPYDDAANRLGSWSGLMAQSDHSAPA
DGFGAGDVKTARMFGRNFAETLHRIL

Sequences:

>Translated_186_residues
MKKLAIIYHSAHGHTRHIASCVRQGAASVADTEAQLLNAEDLAGAPDTLLGYDAYILGSPTYLGGVSGPFKSFMDATGRL
WRTQQLKGKLAAGFTVSSLPAGDKQSTLMSMFVFCMQHGMLWVGNPILPEQHAGVPYDDAANRLGSWSGLMAQSDHSAPA
DGFGAGDVKTARMFGRNFAETLHRIL
>Mature_186_residues
MKKLAIIYHSAHGHTRHIASCVRQGAASVADTEAQLLNAEDLAGAPDTLLGYDAYILGSPTYLGGVSGPFKSFMDATGRL
WRTQQLKGKLAAGFTVSSLPAGDKQSTLMSMFVFCMQHGMLWVGNPILPEQHAGVPYDDAANRLGSWSGLMAQSDHSAPA
DGFGAGDVKTARMFGRNFAETLHRIL

Specific function: Seems To Enhance The Formation And/Or Stability Of Noncovalent Complexes Between The Trp Repressor Protein And Operator-Bearing DNA. However, Wrba Does Not Specifically Influence The Affinity Or Mode Of Binding Of Trpr To Its Operator. It Seems Possible T

COG id: COG0655

COG function: function code R; Multimeric flavodoxin WrbA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1787239, Length=140, Percent_Identity=31.4285714285714, Blast_Score=73, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319849, Length=215, Percent_Identity=28.3720930232558, Blast_Score=72, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6320235, Length=214, Percent_Identity=27.5700934579439, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR010089
- InterPro:   IPR005025 [H]

Pfam domain/function: PF03358 FMN_red [H]

EC number: NA

Molecular weight: Translated: 19867; Mature: 19867

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: PS00201 FLAVODOXIN ; PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLAIIYHSAHGHTRHIASCVRQGAASVADTEAQLLNAEDLAGAPDTLLGYDAYILGSP
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHCCCEEEECCC
TYLGGVSGPFKSFMDATGRLWRTQQLKGKLAAGFTVSSLPAGDKQSTLMSMFVFCMQHGM
HHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCE
LWVGNPILPEQHAGVPYDDAANRLGSWSGLMAQSDHSAPADGFGAGDVKTARMFGRNFAE
EEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TLHRIL
HHHHHC
>Mature Secondary Structure
MKKLAIIYHSAHGHTRHIASCVRQGAASVADTEAQLLNAEDLAGAPDTLLGYDAYILGSP
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCHHHCCCEEEECCC
TYLGGVSGPFKSFMDATGRLWRTQQLKGKLAAGFTVSSLPAGDKQSTLMSMFVFCMQHGM
HHCCCCCHHHHHHHHHHHHHHHHHHHHCHHHCCEEECCCCCCCHHHHHHHHHHHHHHCCE
LWVGNPILPEQHAGVPYDDAANRLGSWSGLMAQSDHSAPADGFGAGDVKTARMFGRNFAE
EEECCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
TLHRIL
HHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA