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The map label for this gene is ubiC

Identifier: 73542544

GI number: 73542544

Start: 3133404

End: 3133988

Strand: Reverse

Name: ubiC

Synonym: Reut_A2859

Alternate gene names: 73542544

Gene position: 3133988-3133404 (Counterclockwise)

Preceding gene: 73542545

Following gene: 73542543

Centisome position: 82.33

GC content: 68.89

Gene sequence:

>585_bases
ATGAGCGCGCAATACGCGCGCCGCTGCGGCTGGACCTGCCACCTGCCCTTCGATCCGACGATTCCGCCGAACCTGCGGCA
TTGGGTCACGGGTGAAGGCTCGCTGACCGCGCGACTGGTGGCCGCTTCCGAACGTTTTCGCGTGCGCCGCCTGTTCCAGG
CATCGGCGCGACCTTTCCTCGACGAATGGCAGGTGCTCGGTCAATGCGGCCGCGAACCGGCGCTGACACGCGAAGTACTG
CTGATCTGCGACGAACAGCCCGCCATCTACGCCCACACCGTCGTGCGCGAACGGCATGCGCGCCGTGACTGGCCGTTCCT
GCGCGGGCTCGGCGAGCGCCCGCTCGGCGGGCGCCTGTTCGTCGACCCGGCCGTGCGGCGCGATCCGTTCCAGTTTGCGC
GGCTGCTGCCGCACCATCCGCTGCGTCAGGCGCTGCTGCGGATCCTGCCGGCTATGGCACCGGTACCCATGCTGCCTGCG
CGCCGTTCCGTATTCCGGCGCGGCGCCGGCGTCATGCTCGTGACAGAGGTCTTTTTGCCGGACCTGCTGACACGGCCATC
GCGGGGACTCGGGCAGAGATATTGA

Upstream 100 bases:

>100_bases
CCGGCAGCGACCACGGCATCAGCGAGTTTGCCGACTACGTTGACGACGTATTGACTTTCTGCGGCTACGGGCCTGGCGGC
GTGGTGCCGGGCCGCGCGGC

Downstream 100 bases:

>100_bases
TCAGATCCGGGCCTCGCCTGTTTGACACACTACCAAGACCATCAAGAGAAGACATCATGAAATTGCAGGGTCGCGTTGCC
ATCATCACCGGCGCAGCCGC

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 194; Mature: 193

Protein sequence:

>194_residues
MSAQYARRCGWTCHLPFDPTIPPNLRHWVTGEGSLTARLVAASERFRVRRLFQASARPFLDEWQVLGQCGREPALTREVL
LICDEQPAIYAHTVVRERHARRDWPFLRGLGERPLGGRLFVDPAVRRDPFQFARLLPHHPLRQALLRILPAMAPVPMLPA
RRSVFRRGAGVMLVTEVFLPDLLTRPSRGLGQRY

Sequences:

>Translated_194_residues
MSAQYARRCGWTCHLPFDPTIPPNLRHWVTGEGSLTARLVAASERFRVRRLFQASARPFLDEWQVLGQCGREPALTREVL
LICDEQPAIYAHTVVRERHARRDWPFLRGLGERPLGGRLFVDPAVRRDPFQFARLLPHHPLRQALLRILPAMAPVPMLPA
RRSVFRRGAGVMLVTEVFLPDLLTRPSRGLGQRY
>Mature_193_residues
SAQYARRCGWTCHLPFDPTIPPNLRHWVTGEGSLTARLVAASERFRVRRLFQASARPFLDEWQVLGQCGREPALTREVLL
ICDEQPAIYAHTVVRERHARRDWPFLRGLGERPLGGRLFVDPAVRRDPFQFARLLPHHPLRQALLRILPAMAPVPMLPAR
RSVFRRGAGVMLVTEVFLPDLLTRPSRGLGQRY

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_CUPPJ (Q46XB3)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_297064.1
- ProteinModelPortal:   Q46XB3
- SMR:   Q46XB3
- GeneID:   3611870
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A2859
- NMPDR:   fig|264198.3.peg.2469
- HOGENOM:   HBG644467
- OMA:   GTPYVAA
- ProtClustDB:   CLSK939614
- BioCyc:   REUT264198:REUT_A2859-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 22257; Mature: 22126

Theoretical pI: Translated: 11.90; Mature: 11.90

Prosite motif: NA

Important sites: BINDING 77-77 BINDING 115-115

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQYARRCGWTCHLPFDPTIPPNLRHWVTGEGSLTARLVAASERFRVRRLFQASARPFL
CCCCHHHHCCCEEECCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCH
DEWQVLGQCGREPALTREVLLICDEQPAIYAHTVVRERHARRDWPFLRGLGERPLGGRLF
HHHHHHHHCCCCCCCCCEEHEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEE
VDPAVRRDPFQFARLLPHHPLRQALLRILPAMAPVPMLPARRSVFRRGAGVMLVTEVFLP
ECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEHHHHHHH
DLLTRPSRGLGQRY
HHHCCCCCCCCCCC
>Mature Secondary Structure 
SAQYARRCGWTCHLPFDPTIPPNLRHWVTGEGSLTARLVAASERFRVRRLFQASARPFL
CCCHHHHCCCEEECCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHCCCCH
DEWQVLGQCGREPALTREVLLICDEQPAIYAHTVVRERHARRDWPFLRGLGERPLGGRLF
HHHHHHHHCCCCCCCCCEEHEEECCCCCHHHHHHHHHHHHCCCCHHHHCCCCCCCCCEEE
VDPAVRRDPFQFARLLPHHPLRQALLRILPAMAPVPMLPARRSVFRRGAGVMLVTEVFLP
ECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCEEHHHHHHH
DLLTRPSRGLGQRY
HHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA