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The map label for this gene is btuE [C]

Identifier: 73542483

GI number: 73542483

Start: 3067521

End: 3068015

Strand: Reverse

Name: btuE [C]

Synonym: Reut_A2798

Alternate gene names: 73542483

Gene position: 3068015-3067521 (Counterclockwise)

Preceding gene: 73542484

Following gene: 73542471

Centisome position: 80.6

GC content: 63.64

Gene sequence:

>495_bases
ATGAGCAATGTCTACCAGTTCGAAGCCAAGTCCCTCGCGGGGCAGCCCGTGCCGCTGTCGCAGTTCCGCGGCAAGGTACT
GCTGATCGTCAACACCGCCAGCGAATGCGGCTTTACGCCGCAGTACGCGGGCCTGCAGGCCCTGCACGACGCGTACGCCG
CGCGCGGACTCGAAGTGCTGGGATTCCCGTGCAACCAGTTCGGCAAGCAGGAGCCAGGCGACGCGCAGCAGATCGGCCAG
TTCTGCGAATCGCGCTTCAGCGTCAAGTTTCCGATGTTCGCCAAGATCGACGTGAAGGGGCCTGACGCGCACCCGCTATA
CCAATGGCTCACCAGCGCGAAGCGCGGCGTGCTCGGCACGCAGGCAATCAAGTGGAATTTCACCAAGTTCCTGCTGCGCC
GTGACGGCACGGTCTACAAGCGCTACGGGTCGATCACCAAGCCGGAAGAGATCCGCGCGGATATCGAAACGCTGCTGGCC
GATCCGGCTGCCTGA

Upstream 100 bases:

>100_bases
AAGCTGCACAGTGCGACCAGGAAGGACAGCGATTTGGGTGCCGGCACCGAGCACTTGAACGTTATCTGATCCGCGCGTCC
GTTCCAGGAGCCAAGTCCGC

Downstream 100 bases:

>100_bases
AACACGCTATACGCCACTGGCCCGCACCGCGCGCAGAAAGCCGTTGAGCGAGCGGTCCGGCGTTTCGTGGAAGCGGTCGT
CGAGCATGCGGATTTCGCGG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSNVYQFEAKSLAGQPVPLSQFRGKVLLIVNTASECGFTPQYAGLQALHDAYAARGLEVLGFPCNQFGKQEPGDAQQIGQ
FCESRFSVKFPMFAKIDVKGPDAHPLYQWLTSAKRGVLGTQAIKWNFTKFLLRRDGTVYKRYGSITKPEEIRADIETLLA
DPAA

Sequences:

>Translated_164_residues
MSNVYQFEAKSLAGQPVPLSQFRGKVLLIVNTASECGFTPQYAGLQALHDAYAARGLEVLGFPCNQFGKQEPGDAQQIGQ
FCESRFSVKFPMFAKIDVKGPDAHPLYQWLTSAKRGVLGTQAIKWNFTKFLLRRDGTVYKRYGSITKPEEIRADIETLLA
DPAA
>Mature_163_residues
SNVYQFEAKSLAGQPVPLSQFRGKVLLIVNTASECGFTPQYAGLQALHDAYAARGLEVLGFPCNQFGKQEPGDAQQIGQF
CESRFSVKFPMFAKIDVKGPDAHPLYQWLTSAKRGVLGTQAIKWNFTKFLLRRDGTVYKRYGSITKPEEIRADIETLLAD
PAA

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=156, Percent_Identity=47.4358974358974, Blast_Score=145, Evalue=2e-35,
Organism=Homo sapiens, GI90903240, Length=156, Percent_Identity=47.4358974358974, Blast_Score=144, Evalue=4e-35,
Organism=Homo sapiens, GI15618997, Length=160, Percent_Identity=42.5, Blast_Score=124, Evalue=3e-29,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=48.8549618320611, Blast_Score=122, Evalue=1e-28,
Organism=Homo sapiens, GI192455698, Length=160, Percent_Identity=35.625, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI41406084, Length=183, Percent_Identity=37.1584699453552, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI6006001, Length=181, Percent_Identity=35.3591160220994, Blast_Score=99, Evalue=1e-21,
Organism=Homo sapiens, GI4557629, Length=182, Percent_Identity=35.7142857142857, Blast_Score=98, Evalue=4e-21,
Organism=Homo sapiens, GI33186887, Length=172, Percent_Identity=33.1395348837209, Blast_Score=83, Evalue=9e-17,
Organism=Homo sapiens, GI32967607, Length=179, Percent_Identity=31.2849162011173, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI41406082, Length=70, Percent_Identity=54.2857142857143, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788003, Length=161, Percent_Identity=43.4782608695652, Blast_Score=137, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=47.5, Blast_Score=150, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI17506887, Length=162, Percent_Identity=46.9135802469136, Blast_Score=150, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI71993584, Length=157, Percent_Identity=38.8535031847134, Blast_Score=124, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI193210707, Length=163, Percent_Identity=40.4907975460123, Blast_Score=123, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17550320, Length=184, Percent_Identity=32.6086956521739, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI193209493, Length=186, Percent_Identity=31.1827956989247, Blast_Score=96, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71993573, Length=94, Percent_Identity=39.3617021276596, Blast_Score=80, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=42.1052631578947, Blast_Score=74, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193210709, Length=71, Percent_Identity=46.4788732394366, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=50.9316770186335, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6319721, Length=159, Percent_Identity=48.4276729559748, Blast_Score=174, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6322826, Length=162, Percent_Identity=41.9753086419753, Blast_Score=149, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24656777, Length=161, Percent_Identity=44.7204968944099, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24656772, Length=161, Percent_Identity=44.7204968944099, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24656767, Length=161, Percent_Identity=44.7204968944099, Blast_Score=138, Evalue=2e-33,
Organism=Drosophila melanogaster, GI85726443, Length=159, Percent_Identity=44.0251572327044, Blast_Score=128, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18192; Mature: 18061

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1 ; PS00763 GLUTATHIONE_PEROXID_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVYQFEAKSLAGQPVPLSQFRGKVLLIVNTASECGFTPQYAGLQALHDAYAARGLEVL
CCCCCCCHHHHCCCCCCCHHHHCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCCEE
GFPCNQFGKQEPGDAQQIGQFCESRFSVKFPMFAKIDVKGPDAHPLYQWLTSAKRGVLGT
ECCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCC
QAIKWNFTKFLLRRDGTVYKRYGSITKPEEIRADIETLLADPAA
HHHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SNVYQFEAKSLAGQPVPLSQFRGKVLLIVNTASECGFTPQYAGLQALHDAYAARGLEVL
CCCCCCHHHHCCCCCCCHHHHCCEEEEEEECCHHCCCCCCHHHHHHHHHHHHHCCCCEE
GFPCNQFGKQEPGDAQQIGQFCESRFSVKFPMFAKIDVKGPDAHPLYQWLTSAKRGVLGT
ECCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCC
QAIKWNFTKFLLRRDGTVYKRYGSITKPEEIRADIETLLADPAA
HHHHHHHHHHHHHCCCHHEECCCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]