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The map label for this gene is aes [C]

Identifier: 73542387

GI number: 73542387

Start: 2965133

End: 2966038

Strand: Reverse

Name: aes [C]

Synonym: Reut_A2702

Alternate gene names: 73542387

Gene position: 2966038-2965133 (Counterclockwise)

Preceding gene: 73542389

Following gene: 73542382

Centisome position: 77.92

GC content: 69.21

Gene sequence:

>906_bases
ATGCCCGCACAATCCTCCCTGTCCAGCCTGGCCCGGTTGCCTTCGCAGGACCCGGCCTTTTACGAGCGAGAATACAACAA
CCGTGCGCGCGTGCCCGACAACGCCGAGCACATGGCGCGCTGGGCGGGGCTGTCGGCGGAGGTGCGGGCGCGTGGCGGCT
ATCAGGAGGATCTGAGCTACGCGGCGCCCGGTGCGACCCATGCGCAGGACCAGCGGCTCGACTACTTCCCGGGCACCGGC
GAGCGTCCGCCGCTGCTGGTCTTCGTGCATGGCGGCTATTTCCGCGCGCTGGACAAGCGCGACCACAGCTTCGTGGCCAG
CGAGTTGCCGCGGCTCGGCGTATCCGTGGCGGTGGTGAACTATTCGCTGTGCCCGTCCGTGACGGTGCCCGCCATCGTGC
GCCAGGTGGTGGGCAGCGTGGCGTGGCTCTACCGGCAGTCGGAACGGCTTGGGCATGACCATTCCCGCATCTTCGTGGCG
GGCCATTCGGTCGGCGGCCACCTGGTGGCCATGTTGATGGCGGCGCTATGGCCACAGGTCGGGCCGGATTTGCCGGATGA
CCTGGTCAAGGGCGGCCTGTCGATCAGCGGCCTGTACGACCTCGAACCGCTGCGGCGCGCCGATTTCCTGCAGCGCGACC
TGCGCCTGTCCGAGGAGGACGTGGCGCGCCTGTCGCCGGCGTTCATGCAGCCCGCGACGAACGCGCCGCTGGTGACGGCC
GTCGGCGAACTGGAAGCGGCCGAGTACCACCGCCAGAACGCGCTGATCCGAGCGGCGTGGCCGGCCAATGCGGCGCAGGA
TGTGCCGCTGCCGGGCCGGCACCATTTCAACGTGATGGACGACCTGGCCAATCCCGACAGCACGCTGCTGCGCGCTGTCC
TGACACTGACGGGCGTCAGGACGTAA

Upstream 100 bases:

>100_bases
CGACCATGTGGCGCGTCCGGTGAGTGGGTATTGGTACGGATATCCGCGCGAGCCGGGCAGGGGCTAGCATGCCAGGGTTT
GCCACCTTGTCGAGCCCGCC

Downstream 100 bases:

>100_bases
TCGCTCTCAGTTTTCCAGCACGCGCAGCAGGGACGAGGTATCGTCCTTGCCCCAGCCGTGTTCCATCAGCGACTTCAGCT
GCGCTGAAGTTGCCTGCATG

Product: hypothetical protein

Products: alcohol; a carboxylate [C]

Alternate protein names: Esterase/Lipase/Thioesterase; Esterase/Lipase-Like Protein; Arylformamidase; Lipase; Esterase/Lipase; Esterase/Lipase/Thioesterase Family Protein; N-Acetylanthranilate Amidase; Alpha/Beta Hydrolase Domain-Containing Protein; Lipase/Esterase; Carboxylesterase Family Protein; Hydrolase; Alpha/Beta Hydrolase Fold-3 Domain Protein; Esterase/Lipase/Thiestherase Protein; Aylformamidase; Alpha/Beta Hydrolase Fold-3 Domain-Containing Protein; Alpha/Beta Hydrolase; Alpha/Beta Hydrolase Fold; Para-Nitrobenzyl Esterase

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MPAQSSLSSLARLPSQDPAFYEREYNNRARVPDNAEHMARWAGLSAEVRARGGYQEDLSYAAPGATHAQDQRLDYFPGTG
ERPPLLVFVHGGYFRALDKRDHSFVASELPRLGVSVAVVNYSLCPSVTVPAIVRQVVGSVAWLYRQSERLGHDHSRIFVA
GHSVGGHLVAMLMAALWPQVGPDLPDDLVKGGLSISGLYDLEPLRRADFLQRDLRLSEEDVARLSPAFMQPATNAPLVTA
VGELEAAEYHRQNALIRAAWPANAAQDVPLPGRHHFNVMDDLANPDSTLLRAVLTLTGVRT

Sequences:

>Translated_301_residues
MPAQSSLSSLARLPSQDPAFYEREYNNRARVPDNAEHMARWAGLSAEVRARGGYQEDLSYAAPGATHAQDQRLDYFPGTG
ERPPLLVFVHGGYFRALDKRDHSFVASELPRLGVSVAVVNYSLCPSVTVPAIVRQVVGSVAWLYRQSERLGHDHSRIFVA
GHSVGGHLVAMLMAALWPQVGPDLPDDLVKGGLSISGLYDLEPLRRADFLQRDLRLSEEDVARLSPAFMQPATNAPLVTA
VGELEAAEYHRQNALIRAAWPANAAQDVPLPGRHHFNVMDDLANPDSTLLRAVLTLTGVRT
>Mature_300_residues
PAQSSLSSLARLPSQDPAFYEREYNNRARVPDNAEHMARWAGLSAEVRARGGYQEDLSYAAPGATHAQDQRLDYFPGTGE
RPPLLVFVHGGYFRALDKRDHSFVASELPRLGVSVAVVNYSLCPSVTVPAIVRQVVGSVAWLYRQSERLGHDHSRIFVAG
HSVGGHLVAMLMAALWPQVGPDLPDDLVKGGLSISGLYDLEPLRRADFLQRDLRLSEEDVARLSPAFMQPATNAPLVTAV
GELEAAEYHRQNALIRAAWPANAAQDVPLPGRHHFNVMDDLANPDSTLLRAVLTLTGVRT

Specific function: Has An Esterase Activity. Triacetyl Glycerol (Triacetin) Is A Substrate Of The Enzyme. [C]

COG id: COG0657

COG function: function code I; Esterase/lipase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI192807282, Length=266, Percent_Identity=30.4511278195489, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI224465228, Length=271, Percent_Identity=29.8892988929889, Blast_Score=104, Evalue=9e-23,
Organism=Drosophila melanogaster, GI19920830, Length=229, Percent_Identity=26.2008733624454, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.1.- [C]

Molecular weight: Translated: 32972; Mature: 32840

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQSSLSSLARLPSQDPAFYEREYNNRARVPDNAEHMARWAGLSAEVRARGGYQEDLSY
CCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHH
AAPGATHAQDQRLDYFPGTGERPPLLVFVHGGYFRALDKRDHSFVASELPRLGVSVAVVN
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEHHCCCCHHHHHHHHHHCCCEEEEEE
YSLCPSVTVPAIVRQVVGSVAWLYRQSERLGHDHSRIFVAGHSVGGHLVAMLMAALWPQV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
GPDLPDDLVKGGLSISGLYDLEPLRRADFLQRDLRLSEEDVARLSPAFMQPATNAPLVTA
CCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCHHHHCCCCCCCCEEH
VGELEAAEYHRQNALIRAAWPANAAQDVPLPGRHHFNVMDDLANPDSTLLRAVLTLTGVR
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCC
T
C
>Mature Secondary Structure 
PAQSSLSSLARLPSQDPAFYEREYNNRARVPDNAEHMARWAGLSAEVRARGGYQEDLSY
CCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHH
AAPGATHAQDQRLDYFPGTGERPPLLVFVHGGYFRALDKRDHSFVASELPRLGVSVAVVN
CCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEHHCCCCHHHHHHHHHHCCCEEEEEE
YSLCPSVTVPAIVRQVVGSVAWLYRQSERLGHDHSRIFVAGHSVGGHLVAMLMAALWPQV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHC
GPDLPDDLVKGGLSISGLYDLEPLRRADFLQRDLRLSEEDVARLSPAFMQPATNAPLVTA
CCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCHHHHCCCCCCCCEEH
VGELEAAEYHRQNALIRAAWPANAAQDVPLPGRHHFNVMDDLANPDSTLLRAVLTLTGVR
HHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCC
T
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Carboxylic ester; H2O [C]

Specific reaction: Carboxylic ester + H2O = an alcohol + carboxylate [C]

General reaction: Hydrolase; Acting on ester bonds; Carboxylic ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA