Click here to switch to the map view.

The map label for this gene is cysH1 [H]

Identifier: 73542379

GI number: 73542379

Start: 2956675

End: 2957475

Strand: Reverse

Name: cysH1 [H]

Synonym: Reut_A2694

Alternate gene names: 73542379

Gene position: 2957475-2956675 (Counterclockwise)

Preceding gene: 73542380

Following gene: 73542378

Centisome position: 77.69

GC content: 66.42

Gene sequence:

>801_bases
ATGAGCGGCCTGAGCGACATCGCAGTCGTGGATGGCGGCGCGCCGGCATCGGCGCTGCGTCCCACGCTGTGGACCATGCC
CGAGTACACGGGCAGCCTGGCGGACCTCGACGAGAAGGAACGCGAGCTGTCGGCCCGCCTGGCCGGCATTGCCGCACGCT
TCTTCCGCGCGCGTTTTGCCACTAGCCTTGCTGCCGAAGACATGGTGCTGACCGACGCGATCCTGCGCGGCACGCCGGCC
GTGCGCGCGGGCATCCGCGTGTTCACGCTGAACACGGGCCGCCTGCACGCCGAAACGCTGGCTGTGCTGGACGAGGTGAA
GGTGCATTACGGCTACACCGTCGAGCAGTTCACGCCGGACACCGAGGCCGTCGAGAACTACCTGAAGAAGCATGGCCTGA
ACGCGTTTTACGACAGCATCGACCTGCGCAAGGATTGCTGCGGCATCCGCAAGGTCGAGCCGCTCAACCGCGCGCTGTCG
CACGCGGACGCCTGGATGACCGGCCAGCGCCGCGAGCAAGCCGTCACGCGTTCCGAACTGCCGTTCGAGGAAATGGACGA
AGCTCGCGCCATCCCGAAGTTCAATCCGCTTGCGGACTGGACCGAGGCCGAGGTGTGGGCATACCTGAAGCGCCACAACG
TCCCGGTGAACGCGCTGCATGCCAAGGGCTACCCCAGCATTGGCTGCGAACCTTGTACGCGTGCGGTGCGCGCGGGCGAG
GACCTGCGCGCCGGGCGCTGGTGGTGGGAGAGCAAGGACTCGAAAGAGTGCGGGCTCCACGAACAGAACATCAAGCATTG
A

Upstream 100 bases:

>100_bases
AGGGCTTCACCGAATTCACCGTGACCTACCAGGCTTCGGTCGATGAGCCGCTGCCGCTGTTCCGCCGCGCACGTGCCGAG
GTTGGCGCAAGGGAATCGGC

Downstream 100 bases:

>100_bases
CGCATTGAAGCATTCGAGGCCGAACGACATGGGCATCATGAACGACATCGCAAGCGCCACCAGCAGCGTGGCGCACTTGC
TGCAGGTACAGAACGATCAC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MSGLSDIAVVDGGAPASALRPTLWTMPEYTGSLADLDEKERELSARLAGIAARFFRARFATSLAAEDMVLTDAILRGTPA
VRAGIRVFTLNTGRLHAETLAVLDEVKVHYGYTVEQFTPDTEAVENYLKKHGLNAFYDSIDLRKDCCGIRKVEPLNRALS
HADAWMTGQRREQAVTRSELPFEEMDEARAIPKFNPLADWTEAEVWAYLKRHNVPVNALHAKGYPSIGCEPCTRAVRAGE
DLRAGRWWWESKDSKECGLHEQNIKH

Sequences:

>Translated_266_residues
MSGLSDIAVVDGGAPASALRPTLWTMPEYTGSLADLDEKERELSARLAGIAARFFRARFATSLAAEDMVLTDAILRGTPA
VRAGIRVFTLNTGRLHAETLAVLDEVKVHYGYTVEQFTPDTEAVENYLKKHGLNAFYDSIDLRKDCCGIRKVEPLNRALS
HADAWMTGQRREQAVTRSELPFEEMDEARAIPKFNPLADWTEAEVWAYLKRHNVPVNALHAKGYPSIGCEPCTRAVRAGE
DLRAGRWWWESKDSKECGLHEQNIKH
>Mature_265_residues
SGLSDIAVVDGGAPASALRPTLWTMPEYTGSLADLDEKERELSARLAGIAARFFRARFATSLAAEDMVLTDAILRGTPAV
RAGIRVFTLNTGRLHAETLAVLDEVKVHYGYTVEQFTPDTEAVENYLKKHGLNAFYDSIDLRKDCCGIRKVEPLNRALSH
ADAWMTGQRREQAVTRSELPFEEMDEARAIPKFNPLADWTEAEVWAYLKRHNVPVNALHAKGYPSIGCEPCTRAVRAGED
LRAGRWWWESKDSKECGLHEQNIKH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=188, Percent_Identity=31.9148936170213, Blast_Score=76, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6325425, Length=182, Percent_Identity=36.2637362637363, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 29769; Mature: 29638

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGLSDIAVVDGGAPASALRPTLWTMPEYTGSLADLDEKERELSARLAGIAARFFRARFA
CCCCCCEEEECCCCCHHHHCCHHHCCCHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TSLAAEDMVLTDAILRGTPAVRAGIRVFTLNTGRLHAETLAVLDEVKVHYGYTVEQFTPD
HHHHHHHHHHHHHHHHCCHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHCCCC
TEAVENYLKKHGLNAFYDSIDLRKDCCGIRKVEPLNRALSHADAWMTGQRREQAVTRSEL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
PFEEMDEARAIPKFNPLADWTEAEVWAYLKRHNVPVNALHAKGYPSIGCEPCTRAVRAGE
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCC
DLRAGRWWWESKDSKECGLHEQNIKH
CCCCCCCCCCCCCCCCCCCCHHCCCC
>Mature Secondary Structure 
SGLSDIAVVDGGAPASALRPTLWTMPEYTGSLADLDEKERELSARLAGIAARFFRARFA
CCCCCEEEECCCCCHHHHCCHHHCCCHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHH
TSLAAEDMVLTDAILRGTPAVRAGIRVFTLNTGRLHAETLAVLDEVKVHYGYTVEQFTPD
HHHHHHHHHHHHHHHHCCHHHHHCEEEEEEECCCHHHHHHHHHHHHHHHCCCCHHHCCCC
TEAVENYLKKHGLNAFYDSIDLRKDCCGIRKVEPLNRALSHADAWMTGQRREQAVTRSEL
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCC
PFEEMDEARAIPKFNPLADWTEAEVWAYLKRHNVPVNALHAKGYPSIGCEPCTRAVRAGE
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHCCC
DLRAGRWWWESKDSKECGLHEQNIKH
CCCCCCCCCCCCCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]