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The map label for this gene is yybO [H]

Identifier: 73542315

GI number: 73542315

Start: 2884938

End: 2886215

Strand: Reverse

Name: yybO [H]

Synonym: Reut_A2630

Alternate gene names: 73542315

Gene position: 2886215-2884938 (Counterclockwise)

Preceding gene: 73542320

Following gene: 73542309

Centisome position: 75.82

GC content: 64.63

Gene sequence:

>1278_bases
ATGACGACCTCTGCTGCTACCCGATCTTCCATGGCCCGCCCGGAACACGGACCTGTTACAGACGCCCGCTGGCGGGTTCT
GGCGGTTTTTTCGCTTGGATTTCTGGTTTCCTACGTATTCCGCGGTGTCAATCTGGGCTTCGCGCCGCACTTGATTCGTG
AGCTGGGACTGAGCGCTGGTGACCTCGGCCTGCTCACCAGCTTCTACTTCCTCGGGTTCGCCGCGGCCCAACTGCCGGCC
GGCATCCTGCTGGATCGGTATGGGCCACGCAAGACCGAAGCTGCGATGCTTTTGGCAGCAGTGGCCGGATCCATGTTGTT
TGCGCTGGCCCCCGGCATGGCCGGATTGGCTGCGGGGCGGCTGTTGATCGGGATCGGTGTTTCGGTTTGCCTTGGCGCGG
CCATCCAGGCGCTGTCGATGTGGTTCCCGCTGTCGCGTATGCCTTTGCTAAACGGTCTCGTCATGGCGATTGGCGGGCTG
GGGGCGGTGGCTGTCGGTTCGCCGCTGGCGTGGCTGCTGTCCTGGACGGACTGGAGATCCGTCAGCACTGGGCTGGCCTT
CGTATCGCTGGCCATGGCCGCCTTGCTGTGGTTCGGCGTGCCGGACAAGGCCCGGCCGCGGCGTGAAAGTCTGGCGGAGC
AATTGCGCGGCACGCGTCAAATTCTTGGCAGCGAACGATTCTGGCGCGTGGTGCCGCTGACCTTGCTTAACCAGGGCGTA
TTCCTGGCGGTGCAAACGTTGTGGGTGGGTGCCTTCATGCGTGATGTGTCCGGATTTGCGCCTGACCAGAGCGCGCGACT
GGTATCAGTCATTGGTCTGGCGATGATGGCCGGGTGCGTAGGGTCCGGCTGGGCGGCACGTCATCTGGAGCGGCTCGGCG
TAAGCCTGAAGGCCTTTGCCGGCGCTGGCATGACGGGCTTCATCGTGGTCCAGATATTGATCATGGCCCAGGTGCCGCTG
TCGCCAGTGCTGCTGTGGGCGGCCTATGGCGTGTTCGGCTCGAGCGGCATCCTGACCTATGCCGTTCTGGCGCGCAGTTT
CCCGGATGCCCTGATCGGCCGCGCGACGACAGCCATGACACTTACGGTGTTCCTGGCCACGTTCCTCTGCCAGGTCGGGA
TTGGCCAGGTATTGGACCTGTGGCCGGCCACGGGCGGCCGCTATCCCGCTACTGCCCACCTGTCGGCATGGGCTGGCTTG
GTAACGCTGCAGGCCCTTGCGGCAGTGTGGTATGCGATCGGGCGCGGCGGCCCGACCGATCCGCGCAGGGTTCAGTAG

Upstream 100 bases:

>100_bases
CGATCGATAGGTTTGCGGGCCATGGCCGTCAAATTCTACTCACAATTGCCGACCGTAACTTTCGTTGGCGTTGCACCATG
CTGGTGAGGACAATGGCGGC

Downstream 100 bases:

>100_bases
ACTCCCGGCAACACGCGAAACCGTACTTTCTCGCGATACCGGCAATATTCCGGGTCGTCGGACAATAGTGCTTCTTCGCG
CCTGATACGCATGACCTGAA

Product: major facilitator transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MTTSAATRSSMARPEHGPVTDARWRVLAVFSLGFLVSYVFRGVNLGFAPHLIRELGLSAGDLGLLTSFYFLGFAAAQLPA
GILLDRYGPRKTEAAMLLAAVAGSMLFALAPGMAGLAAGRLLIGIGVSVCLGAAIQALSMWFPLSRMPLLNGLVMAIGGL
GAVAVGSPLAWLLSWTDWRSVSTGLAFVSLAMAALLWFGVPDKARPRRESLAEQLRGTRQILGSERFWRVVPLTLLNQGV
FLAVQTLWVGAFMRDVSGFAPDQSARLVSVIGLAMMAGCVGSGWAARHLERLGVSLKAFAGAGMTGFIVVQILIMAQVPL
SPVLLWAAYGVFGSSGILTYAVLARSFPDALIGRATTAMTLTVFLATFLCQVGIGQVLDLWPATGGRYPATAHLSAWAGL
VTLQALAAVWYAIGRGGPTDPRRVQ

Sequences:

>Translated_425_residues
MTTSAATRSSMARPEHGPVTDARWRVLAVFSLGFLVSYVFRGVNLGFAPHLIRELGLSAGDLGLLTSFYFLGFAAAQLPA
GILLDRYGPRKTEAAMLLAAVAGSMLFALAPGMAGLAAGRLLIGIGVSVCLGAAIQALSMWFPLSRMPLLNGLVMAIGGL
GAVAVGSPLAWLLSWTDWRSVSTGLAFVSLAMAALLWFGVPDKARPRRESLAEQLRGTRQILGSERFWRVVPLTLLNQGV
FLAVQTLWVGAFMRDVSGFAPDQSARLVSVIGLAMMAGCVGSGWAARHLERLGVSLKAFAGAGMTGFIVVQILIMAQVPL
SPVLLWAAYGVFGSSGILTYAVLARSFPDALIGRATTAMTLTVFLATFLCQVGIGQVLDLWPATGGRYPATAHLSAWAGL
VTLQALAAVWYAIGRGGPTDPRRVQ
>Mature_424_residues
TTSAATRSSMARPEHGPVTDARWRVLAVFSLGFLVSYVFRGVNLGFAPHLIRELGLSAGDLGLLTSFYFLGFAAAQLPAG
ILLDRYGPRKTEAAMLLAAVAGSMLFALAPGMAGLAAGRLLIGIGVSVCLGAAIQALSMWFPLSRMPLLNGLVMAIGGLG
AVAVGSPLAWLLSWTDWRSVSTGLAFVSLAMAALLWFGVPDKARPRRESLAEQLRGTRQILGSERFWRVVPLTLLNQGVF
LAVQTLWVGAFMRDVSGFAPDQSARLVSVIGLAMMAGCVGSGWAARHLERLGVSLKAFAGAGMTGFIVVQILIMAQVPLS
PVLLWAAYGVFGSSGILTYAVLARSFPDALIGRATTAMTLTVFLATFLCQVGIGQVLDLWPATGGRYPATAHLSAWAGLV
TLQALAAVWYAIGRGGPTDPRRVQ

Specific function: Aldohexuronate Transport System. [C]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44805; Mature: 44673

Theoretical pI: Translated: 11.21; Mature: 11.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCC
>Mature Secondary Structure 
TTSAATRSSMARPEHGPVTDARWRVLAVFSLGFLVSYVFRGVNLGFAPHLIRELGLSAG
CCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCC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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]