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The map label for this gene is nudL [H]

Identifier: 73542221

GI number: 73542221

Start: 2781635

End: 2782315

Strand: Reverse

Name: nudL [H]

Synonym: Reut_A2536

Alternate gene names: 73542221

Gene position: 2782315-2781635 (Counterclockwise)

Preceding gene: 73542222

Following gene: 73542219

Centisome position: 73.09

GC content: 64.46

Gene sequence:

>681_bases
ATGCGCCCCGCCTTTGATCCCGAATCTCTCCCGGTCGTCGATACCGACACGCAACGCCCAGCCCTGAGCGCGCCGCGTCT
GCAGTCGGAATTCATCCGCCACCGGCTGCAGGTGCCGCCCGCCTGGGCACCCGAACTTACCGACGAATCACGCGTCTACG
ACCGCAGCCGCGGCTTGCGCGATGCCGCGGTGCTGGTGCCGATCGTCGAGCGCCGCGATGGCCTGACCATACTGCTCACC
GAACGCAATGCCAACCTGAGCGCGCACGCAGGACAGATCAGCTTCCCGGGCGGTCGCCAGGAAAGCTATGACGTGAACCG
AATCGATACGGCCTTGCGGGAAACCGAGGAGGAGGTAGGCCTGGCGCGGGACTACGTGGAAGTGCTGGGCGCGTTGCCGG
ACTACATCACCGGCACCGGCTTTCATGTCAGTCCGGTAGTAGGACTCGTACGCGATGGTTTCACGCTGCGGCCGGATGCC
TCAGAGGTGGCCGATGTTTTTGAGGTGCCGCTGGCCTTCCTGATGAATCCTTCGCACCATGAGCGGCGGCTGTTCCGCTG
GGTCGATGGCGAACGGATGTTCTACGCGATGCCGTTCCCGCGCGAAGGTGGTGGCCATCGCTTTATCTGGGGTGCGACGG
CGGGCATGCTGCGTAACCTCTACCACCTGCTCGCCGCATAA

Upstream 100 bases:

>100_bases
CCTCAGGAAGGGCACCGCAAGGTGCCCTTTTTGCGTTTTGGCAACTGTGCAGGATTGCTGCGCTGCCGGAATGCGGGCAT
CTGTCATACTTGAGGCTGTT

Downstream 100 bases:

>100_bases
CCCTCGGGTAATCAGGCCGCTGCCTGATCGTGCCGCCCGACGCAATGCGGGCAGCTCTTGCCGACCACGTAGTGCGGGCT
TTGCTGCTCTTCGGCCGTCA

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRPAFDPESLPVVDTDTQRPALSAPRLQSEFIRHRLQVPPAWAPELTDESRVYDRSRGLRDAAVLVPIVERRDGLTILLT
ERNANLSAHAGQISFPGGRQESYDVNRIDTALRETEEEVGLARDYVEVLGALPDYITGTGFHVSPVVGLVRDGFTLRPDA
SEVADVFEVPLAFLMNPSHHERRLFRWVDGERMFYAMPFPREGGGHRFIWGATAGMLRNLYHLLAA

Sequences:

>Translated_226_residues
MRPAFDPESLPVVDTDTQRPALSAPRLQSEFIRHRLQVPPAWAPELTDESRVYDRSRGLRDAAVLVPIVERRDGLTILLT
ERNANLSAHAGQISFPGGRQESYDVNRIDTALRETEEEVGLARDYVEVLGALPDYITGTGFHVSPVVGLVRDGFTLRPDA
SEVADVFEVPLAFLMNPSHHERRLFRWVDGERMFYAMPFPREGGGHRFIWGATAGMLRNLYHLLAA
>Mature_226_residues
MRPAFDPESLPVVDTDTQRPALSAPRLQSEFIRHRLQVPPAWAPELTDESRVYDRSRGLRDAAVLVPIVERRDGLTILLT
ERNANLSAHAGQISFPGGRQESYDVNRIDTALRETEEEVGLARDYVEVLGALPDYITGTGFHVSPVVGLVRDGFTLRPDA
SEVADVFEVPLAFLMNPSHHERRLFRWVDGERMFYAMPFPREGGGHRFIWGATAGMLRNLYHLLAA

Specific function: Probably mediates the hydrolysis of some nucleoside diphosphate derivatives [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI157785656, Length=157, Percent_Identity=35.031847133758, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1788115, Length=162, Percent_Identity=41.358024691358, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17536993, Length=140, Percent_Identity=33.5714285714286, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17510677, Length=176, Percent_Identity=32.3863636363636, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI18859683, Length=219, Percent_Identity=32.4200913242009, Blast_Score=91, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR000059 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: NA

Molecular weight: Translated: 25403; Mature: 25403

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAFDPESLPVVDTDTQRPALSAPRLQSEFIRHRLQVPPAWAPELTDESRVYDRSRGLR
CCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCC
DAAVLVPIVERRDGLTILLTERNANLSAHAGQISFPGGRQESYDVNRIDTALRETEEEVG
HHHHEEHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHH
LARDYVEVLGALPDYITGTGFHVSPVVGLVRDGFTLRPDASEVADVFEVPLAFLMNPSHH
HHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCHH
ERRLFRWVDGERMFYAMPFPREGGGHRFIWGATAGMLRNLYHLLAA
HHHHHHHCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRPAFDPESLPVVDTDTQRPALSAPRLQSEFIRHRLQVPPAWAPELTDESRVYDRSRGLR
CCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCC
DAAVLVPIVERRDGLTILLTERNANLSAHAGQISFPGGRQESYDVNRIDTALRETEEEVG
HHHHEEHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHH
LARDYVEVLGALPDYITGTGFHVSPVVGLVRDGFTLRPDASEVADVFEVPLAFLMNPSHH
HHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHCCCCHH
ERRLFRWVDGERMFYAMPFPREGGGHRFIWGATAGMLRNLYHLLAA
HHHHHHHCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA