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The map label for this gene is aer [H]

Identifier: 73542138

GI number: 73542138

Start: 2691316

End: 2692872

Strand: Reverse

Name: aer [H]

Synonym: Reut_A2452

Alternate gene names: 73542138

Gene position: 2692872-2691316 (Counterclockwise)

Preceding gene: 73542139

Following gene: 73542133

Centisome position: 70.74

GC content: 66.73

Gene sequence:

>1557_bases
ATGAGATTGAATCTTCCGGTCACCGACAACGAGTACCGCTTGCCATCGGACGAAGTCATCATCACCAGGACCGATGCGCA
AGGCAATATCGAATACGCCAACCAGGCGTTCTTTCGCAGCAGCGGCTACGACCGTGCCGAAATCATTGGCCAGCCGCAGA
ACATTGTCCGCCACCCCGACATGCCGGCTGCCGCATTCGCCGATATGTGGGCCACGATCCGAGGCGGGACGCCGTGGACT
GGTGTGGTCAAGAACCGGCGCAAGGACGGCGGCTTCTACTGGGTGCTGGCCAATATCACCCCTGTGTTCCAGGACGGCAA
GCCATCGGGTTACCTGTCGGTGAGAACGGCGCCCACGAAGGCACAGGTCACGGCGGCGGCCACGCTCTATGCCGACCTGA
AGCGTGACGCCCAGTCGCGCTGGCGGTTGTCGGGCGGCGAGGCCTTCCGCAAGGGCGCAGCCGGTGTCGTTCAGCGGATA
TTGAGGCTGCCTGTGGTGGCACGCTTGCTCGTGGTACAGGCCGCGCAAGTCGTCCTGATCGCGCTGGCCGCGGCGAGCGC
AACGCTCTGGACGGCGCCGCCCGTTGTTACGTGGTCGCTCGCGGGCGCGGCAGTGGCGATGTGCGGCGCTGCCGCTTGCT
ACCTCGCCTTCAACATCCTGCAGCCCGTGATGCGCCTGAACCGCAGCGCGCTGGCCGTGTTGTCCGGACAGTTGCAGCAC
CGCTTCCCCGAATGCGGCGACGCGCAGACACGACTGCTCGGCCGCTTCCTGAACCAGATGAACGCGCGGCTCGTGGGCGT
GCTGCTGGACACCCGGAATTCGATCGAACGCGTGTGGCAGTCTTCAGTCGGCCTTGCCAGCGGCAATGCCGACCTGTCGG
AGCGTACCGAACAGCAGGCGAGCGCCATCGAGCAGACCACGGCGACGCTCGCGCAGATCACCGAAACCGCGCGGCAGAAT
GCGAGCGATGCGGAGCGTGCGCATCAGGAAGGTCGCAGTACTGCAGACGCCGCGTCGGCGGCGGCAGGCGGCGTGCGCCG
CTCGGCTTCGCTGATGGAGCAGGTGACCACGCAGTCCCGCAGGATCGCGGAGATCACGTCGGTGATCGACGACATCGCCA
TCCAGACTAACCTGCTCGCGCTGAACGCTGCCGTCGAGGCCGCGCGCGCGGGTCAGCACGGCCGTGGCTTTGCCGTGGTA
GCGGGTGAGGTGCGATCGCTCGCGCAGCGCGCCGAAGCGGCTGCCAAGCAGATCAAGGCGCTGATCGAGAACTCGCTCGA
AGTCGTGCAGGCCAGCAGCGATGCTGCCATCAGCGCGGGCAGCGAGATGGACCGCGTGGAGCAGTCGGTGTCGGCGCTGA
CGCGAACGATTTCCGCGATCGCCAACGCCAGCCGCGGGCAGAGCGTGGAGATCGAGCAGACCAGCGCGGCGGTGGAACAG
ATGGCGCACATCACGCAGATGAACGCGGCGCTGGTGGAGGAATCGGCCGCGGCGGCGACAGGGCTGAAGCAGCAGGCCCA
GGCGCTGGAGGATGCGGTGAACGTGCTGGCGAGCTAG

Upstream 100 bases:

>100_bases
TCGCCCGCGGCCAGGCAATGCCGGCCGGGCGGGAACTATCAGGGGCGACTTCCGCAGCGAAGTCGGAGTCAAGGTTGCAA
CAGCACAGACAACCAGCATC

Downstream 100 bases:

>100_bases
TCCACCGGATCGGCGGTGGCTCAGCCAATCGTCGCGATCGGCACGCCCGCGGCCATGAAGATGCCCGCTGCGGCGCGCAG
CACGATGCGGCCGGCACGAT

Product: PAS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MRLNLPVTDNEYRLPSDEVIITRTDAQGNIEYANQAFFRSSGYDRAEIIGQPQNIVRHPDMPAAAFADMWATIRGGTPWT
GVVKNRRKDGGFYWVLANITPVFQDGKPSGYLSVRTAPTKAQVTAAATLYADLKRDAQSRWRLSGGEAFRKGAAGVVQRI
LRLPVVARLLVVQAAQVVLIALAAASATLWTAPPVVTWSLAGAAVAMCGAAACYLAFNILQPVMRLNRSALAVLSGQLQH
RFPECGDAQTRLLGRFLNQMNARLVGVLLDTRNSIERVWQSSVGLASGNADLSERTEQQASAIEQTTATLAQITETARQN
ASDAERAHQEGRSTADAASAAAGGVRRSASLMEQVTTQSRRIAEITSVIDDIAIQTNLLALNAAVEAARAGQHGRGFAVV
AGEVRSLAQRAEAAAKQIKALIENSLEVVQASSDAAISAGSEMDRVEQSVSALTRTISAIANASRGQSVEIEQTSAAVEQ
MAHITQMNAALVEESAAAATGLKQQAQALEDAVNVLAS

Sequences:

>Translated_518_residues
MRLNLPVTDNEYRLPSDEVIITRTDAQGNIEYANQAFFRSSGYDRAEIIGQPQNIVRHPDMPAAAFADMWATIRGGTPWT
GVVKNRRKDGGFYWVLANITPVFQDGKPSGYLSVRTAPTKAQVTAAATLYADLKRDAQSRWRLSGGEAFRKGAAGVVQRI
LRLPVVARLLVVQAAQVVLIALAAASATLWTAPPVVTWSLAGAAVAMCGAAACYLAFNILQPVMRLNRSALAVLSGQLQH
RFPECGDAQTRLLGRFLNQMNARLVGVLLDTRNSIERVWQSSVGLASGNADLSERTEQQASAIEQTTATLAQITETARQN
ASDAERAHQEGRSTADAASAAAGGVRRSASLMEQVTTQSRRIAEITSVIDDIAIQTNLLALNAAVEAARAGQHGRGFAVV
AGEVRSLAQRAEAAAKQIKALIENSLEVVQASSDAAISAGSEMDRVEQSVSALTRTISAIANASRGQSVEIEQTSAAVEQ
MAHITQMNAALVEESAAAATGLKQQAQALEDAVNVLAS
>Mature_518_residues
MRLNLPVTDNEYRLPSDEVIITRTDAQGNIEYANQAFFRSSGYDRAEIIGQPQNIVRHPDMPAAAFADMWATIRGGTPWT
GVVKNRRKDGGFYWVLANITPVFQDGKPSGYLSVRTAPTKAQVTAAATLYADLKRDAQSRWRLSGGEAFRKGAAGVVQRI
LRLPVVARLLVVQAAQVVLIALAAASATLWTAPPVVTWSLAGAAVAMCGAAACYLAFNILQPVMRLNRSALAVLSGQLQH
RFPECGDAQTRLLGRFLNQMNARLVGVLLDTRNSIERVWQSSVGLASGNADLSERTEQQASAIEQTTATLAQITETARQN
ASDAERAHQEGRSTADAASAAAGGVRRSASLMEQVTTQSRRIAEITSVIDDIAIQTNLLALNAAVEAARAGQHGRGFAVV
AGEVRSLAQRAEAAAKQIKALIENSLEVVQASSDAAISAGSEMDRVEQSVSALTRTISAIANASRGQSVEIEQTSAAVEQ
MAHITQMNAALVEESAAAATGLKQQAQALEDAVNVLAS

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=516, Percent_Identity=39.3410852713178, Blast_Score=328, Evalue=6e-91,
Organism=Escherichia coli, GI1787690, Length=298, Percent_Identity=41.9463087248322, Blast_Score=205, Evalue=5e-54,
Organism=Escherichia coli, GI1788195, Length=274, Percent_Identity=42.3357664233577, Blast_Score=190, Evalue=2e-49,
Organism=Escherichia coli, GI1788194, Length=321, Percent_Identity=40.809968847352, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI2367378, Length=306, Percent_Identity=40.1960784313725, Blast_Score=186, Evalue=3e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 55038; Mature: 55038

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNLPVTDNEYRLPSDEVIITRTDAQGNIEYANQAFFRSSGYDRAEIIGQPQNIVRHPD
CEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHHCCCC
MPAAAFADMWATIRGGTPWTGVVKNRRKDGGFYWVLANITPVFQDGKPSGYLSVRTAPTK
CCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCC
AQVTAAATLYADLKRDAQSRWRLSGGEAFRKGAAGVVQRILRLPVVARLLVVQAAQVVLI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAAASATLWTAPPVVTWSLAGAAVAMCGAAACYLAFNILQPVMRLNRSALAVLSGQLQH
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RFPECGDAQTRLLGRFLNQMNARLVGVLLDTRNSIERVWQSSVGLASGNADLSERTEQQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
SAIEQTTATLAQITETARQNASDAERAHQEGRSTADAASAAAGGVRRSASLMEQVTTQSR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAEITSVIDDIAIQTNLLALNAAVEAARAGQHGRGFAVVAGEVRSLAQRAEAAAKQIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
LIENSLEVVQASSDAAISAGSEMDRVEQSVSALTRTISAIANASRGQSVEIEQTSAAVEQ
HHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
MAHITQMNAALVEESAAAATGLKQQAQALEDAVNVLAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLNLPVTDNEYRLPSDEVIITRTDAQGNIEYANQAFFRSSGYDRAEIIGQPQNIVRHPD
CEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHCCCCHHHHCCCC
MPAAAFADMWATIRGGTPWTGVVKNRRKDGGFYWVLANITPVFQDGKPSGYLSVRTAPTK
CCHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCC
AQVTAAATLYADLKRDAQSRWRLSGGEAFRKGAAGVVQRILRLPVVARLLVVQAAQVVLI
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAAASATLWTAPPVVTWSLAGAAVAMCGAAACYLAFNILQPVMRLNRSALAVLSGQLQH
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
RFPECGDAQTRLLGRFLNQMNARLVGVLLDTRNSIERVWQSSVGLASGNADLSERTEQQA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
SAIEQTTATLAQITETARQNASDAERAHQEGRSTADAASAAAGGVRRSASLMEQVTTQSR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIAEITSVIDDIAIQTNLLALNAAVEAARAGQHGRGFAVVAGEVRSLAQRAEAAAKQIKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHH
LIENSLEVVQASSDAAISAGSEMDRVEQSVSALTRTISAIANASRGQSVEIEQTSAAVEQ
HHHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHH
MAHITQMNAALVEESAAAATGLKQQAQALEDAVNVLAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]