| Definition | Ralstonia eutropha JMP134 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_007347 |
| Length | 3,806,533 |
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The map label for this gene is nrdZ [H]
Identifier: 73541801
GI number: 73541801
Start: 2322449
End: 2324935
Strand: Reverse
Name: nrdZ [H]
Synonym: Reut_A2113
Alternate gene names: 73541801
Gene position: 2324935-2322449 (Counterclockwise)
Preceding gene: 73541802
Following gene: 161611258
Centisome position: 61.08
GC content: 66.26
Gene sequence:
>2487_bases ATGAACGCAAACGACCAGATCCTGCGCGGCGCGCTGGCGCCGCAGGAAATCTCGACCGAAGTCCTGCTGGAGAAATACGC CAAAGGCGAGGAGCAGAGCGTCACGGACGTGCGCAAGCGCGTGGCGCGCGCACTCGCGCAGGCCGAGACGGAGGATCAGC GCGAAGGCTGGACCGCGCGTTTTCTTTGGGCGCAGGAGAGCGGTTTTGTGCCGGCTGGGCGCATCAACTCGGCCGCGGGC ACCGGCATCCAGGCCACGCTGATCAATTGCTTTGTGCAGCCCGTGGGCGATTCGGTGTCGGAGCCGCGCGGTGGCAGGCC CAGTATCTATACGGCGGTCGCGCAGGCAGCCGAAACCATGCGGCGCGGCGGCGGCGTCGGCTATGACTTCTCGGCCATCC GGCCGGCCGGTGCGCTGGTGCGCGCGACGCATTCGCGCGCTTCGGGCCCAGTGTCGTTCATGAAGGTGTTCGACGCGTCG TGCGCGACGGTCGAGTCGGCCGGCGCACGGCGCGGCGCGCAGATGGGCGTGCTGCGTTGCGACCACCCCGATATCGAGAG CTTTATTCACGCCAAGGACAAGGGCGATCTCAGCAACTTCAATATTTCGATCGGCGTTACTGACGAGTTCATGCGCGCGG TCGAGCGTGACGAGGAAGTCGAACTTGTGCACGAGGCCGAGCCCGGTGCCGACCTGATCGCCGGCGGCGCCTACCGGCGC GACGACGGCCAGTGGGTCTACCGGCGCATGCCTGCCCGCCTGCTCTGGGATCAGGTCATGCATGCGACCTACGACCATGC CGAGCCCGGCATCCTGTTCCTGTCCCGCATCAACGCCGACAACAACCTCTATTACTGCGAGACCATCGAAGCGACCAATC CGTGTGCCGAGCAGCCGCTGCCGCCATACGGTTGCTGCTGCCTGGGCTCGATCGACCTGACGCGCTTCGTGCGGCAGCCG TTCACGCCGGACAGCGATTTCGACTTCGACGCGTTCGCGGAAGTCGTCCGGGTGTCCACGCGCATGCTGGACAACGTGCT CGACGTGACCTTCTGGCCGCTGCCCGAGCAACAGGCTGAAGCGCAGGCCAAGCGCCGCGTGGGGCTGGGTTTTCTGGGCC TGGGCAGCGCGCTCGTGATGCTTGGCCTGCGCTACGACAGCGAGCCGGCGCGGGTGGTGGCCGCTCGCATCGCCGAACGC ATGCGGGATGAGGCGTACCTTGCATCGACGGAGTTGGCTGCGGAGAAGGGCGCTTTCCCGTTGTTCGACGCCGATGCCTA TTTGCAAAGCGGTTTTGCGAGCCGGCTGCCCGAGCCTGTGCGCCAGGCGATTATGCGCAATGGCCTGCGCAACTCGCACC TGCTGTCGATCGCGCCAACCGGCACCATCACGCTGGCCTTTGCCGACAACGCTTCGAATGGCATCGAACCGGCGTTCTCG TGGACGTACCAGCGCAAGAAGCGCATGCCGGACAACACGTACCGCACGTACGAAGTGGCCGACCACGCATGGCGGCGCTA CCGTCACACGGGTGCGGACATGAACAAGTTGCCGGATGCCTTCGTCACGGCGCTGCAGATGTCGGCGCTGGACCATATGC GCATGCTGCAGGCCGTGCAGCCGTATATCGATACCAGCATCAGCAAGACCGTCAACGTGCCGGAGGATTACCCGTACGAG GCGTTCCGGAACCTCTATCTGGAGGCTTGGAAGGCCGGGCTCAAGGGGCTGGCGACCTATCGGCCCAATAGCGTGCTCGG TGCAGTGTTGTCGGTCAGTGTGCCGGCTGTCGCGGCCTCCTCGACGGCGACGACCGTTGACGACCCGTTGGTGCGGCCGT ATGGCAGCCGCCCCGTGGGCGACCTCGAAGGGGTGACTTCCAAGCTCGACTACATGACCTACGAGGGGCACAAGACCGTC TACCTGACCGTGAACTTCATACGGGTCAGCGGCATGGTGGACGGCAAGCCGGTCGAGATCGAGCGGCCGATCGAGTTCTT CATGCCGGCCGGGCAGCGCAGCGAGGGGCAGCAGTGGATCACGTCGACCATGCGCCTGTTGTCCATGGTGGCGCGCTCCG GCGGCTCGGTGGCGAAGGCGCTGGCCGACATGCGCAATGTCGTATGGGACAAGGGCACGGTCCGCTACGGTACGCTGGCG CGGCAGGACGGCACCGAGGTGCCGCGTTTCCATGATTCCGAGGTGGCGGCCATCGGCTATGCGCTCCAGCGCATCCTGAT CAAGCGCGGCTTTCTTGATGCCGAAGGTATCCAGGTGCCGGTGGCCGAACTGGCAGCGCGCCTGGCCCGCCGCGAGAATG GCGCCGCCGGGGCGGAGAGCGGGAAGGGCAACACGGTCGCCGCTGCCCCTGTCAACCCGGCCCTCGGCACCGGAAAACCA TGCCCGGAGTGTGGCGCGCACGCCCTGCACAAGGTGGACGGCTGCGCCAAGTGCGCCAACTGCGGATACGTGGGCGAGTG CGGCTGA
Upstream 100 bases:
>100_bases TGCGTCGAACTTGCATCGGATTGATCTTGCGCAGGCGCGTTTGCCTGCCGTGGCTGGAGCATACCGGCTGCCCAATCGGA CATGAATGGTGAGCCAAGAC
Downstream 100 bases:
>100_bases CCGGGCCCGGCGCTAGCCCAGTCGGCGCCAAGGCTGGCGGGGGCGGCGGTTGCCGTGGCGGCCGCCGTCGCGGCCCCGCC TTTTGCTACAATCGCCGGCA
Product: ribonucleotide reductase large subunit
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 828; Mature: 828
Protein sequence:
>828_residues MNANDQILRGALAPQEISTEVLLEKYAKGEEQSVTDVRKRVARALAQAETEDQREGWTARFLWAQESGFVPAGRINSAAG TGIQATLINCFVQPVGDSVSEPRGGRPSIYTAVAQAAETMRRGGGVGYDFSAIRPAGALVRATHSRASGPVSFMKVFDAS CATVESAGARRGAQMGVLRCDHPDIESFIHAKDKGDLSNFNISIGVTDEFMRAVERDEEVELVHEAEPGADLIAGGAYRR DDGQWVYRRMPARLLWDQVMHATYDHAEPGILFLSRINADNNLYYCETIEATNPCAEQPLPPYGCCCLGSIDLTRFVRQP FTPDSDFDFDAFAEVVRVSTRMLDNVLDVTFWPLPEQQAEAQAKRRVGLGFLGLGSALVMLGLRYDSEPARVVAARIAER MRDEAYLASTELAAEKGAFPLFDADAYLQSGFASRLPEPVRQAIMRNGLRNSHLLSIAPTGTITLAFADNASNGIEPAFS WTYQRKKRMPDNTYRTYEVADHAWRRYRHTGADMNKLPDAFVTALQMSALDHMRMLQAVQPYIDTSISKTVNVPEDYPYE AFRNLYLEAWKAGLKGLATYRPNSVLGAVLSVSVPAVAASSTATTVDDPLVRPYGSRPVGDLEGVTSKLDYMTYEGHKTV YLTVNFIRVSGMVDGKPVEIERPIEFFMPAGQRSEGQQWITSTMRLLSMVARSGGSVAKALADMRNVVWDKGTVRYGTLA RQDGTEVPRFHDSEVAAIGYALQRILIKRGFLDAEGIQVPVAELAARLARRENGAAGAESGKGNTVAAAPVNPALGTGKP CPECGAHALHKVDGCAKCANCGYVGECG
Sequences:
>Translated_828_residues MNANDQILRGALAPQEISTEVLLEKYAKGEEQSVTDVRKRVARALAQAETEDQREGWTARFLWAQESGFVPAGRINSAAG TGIQATLINCFVQPVGDSVSEPRGGRPSIYTAVAQAAETMRRGGGVGYDFSAIRPAGALVRATHSRASGPVSFMKVFDAS CATVESAGARRGAQMGVLRCDHPDIESFIHAKDKGDLSNFNISIGVTDEFMRAVERDEEVELVHEAEPGADLIAGGAYRR DDGQWVYRRMPARLLWDQVMHATYDHAEPGILFLSRINADNNLYYCETIEATNPCAEQPLPPYGCCCLGSIDLTRFVRQP FTPDSDFDFDAFAEVVRVSTRMLDNVLDVTFWPLPEQQAEAQAKRRVGLGFLGLGSALVMLGLRYDSEPARVVAARIAER MRDEAYLASTELAAEKGAFPLFDADAYLQSGFASRLPEPVRQAIMRNGLRNSHLLSIAPTGTITLAFADNASNGIEPAFS WTYQRKKRMPDNTYRTYEVADHAWRRYRHTGADMNKLPDAFVTALQMSALDHMRMLQAVQPYIDTSISKTVNVPEDYPYE AFRNLYLEAWKAGLKGLATYRPNSVLGAVLSVSVPAVAASSTATTVDDPLVRPYGSRPVGDLEGVTSKLDYMTYEGHKTV YLTVNFIRVSGMVDGKPVEIERPIEFFMPAGQRSEGQQWITSTMRLLSMVARSGGSVAKALADMRNVVWDKGTVRYGTLA RQDGTEVPRFHDSEVAAIGYALQRILIKRGFLDAEGIQVPVAELAARLARRENGAAGAESGKGNTVAAAPVNPALGTGKP CPECGAHALHKVDGCAKCANCGYVGECG >Mature_828_residues MNANDQILRGALAPQEISTEVLLEKYAKGEEQSVTDVRKRVARALAQAETEDQREGWTARFLWAQESGFVPAGRINSAAG TGIQATLINCFVQPVGDSVSEPRGGRPSIYTAVAQAAETMRRGGGVGYDFSAIRPAGALVRATHSRASGPVSFMKVFDAS CATVESAGARRGAQMGVLRCDHPDIESFIHAKDKGDLSNFNISIGVTDEFMRAVERDEEVELVHEAEPGADLIAGGAYRR DDGQWVYRRMPARLLWDQVMHATYDHAEPGILFLSRINADNNLYYCETIEATNPCAEQPLPPYGCCCLGSIDLTRFVRQP FTPDSDFDFDAFAEVVRVSTRMLDNVLDVTFWPLPEQQAEAQAKRRVGLGFLGLGSALVMLGLRYDSEPARVVAARIAER MRDEAYLASTELAAEKGAFPLFDADAYLQSGFASRLPEPVRQAIMRNGLRNSHLLSIAPTGTITLAFADNASNGIEPAFS WTYQRKKRMPDNTYRTYEVADHAWRRYRHTGADMNKLPDAFVTALQMSALDHMRMLQAVQPYIDTSISKTVNVPEDYPYE AFRNLYLEAWKAGLKGLATYRPNSVLGAVLSVSVPAVAASSTATTVDDPLVRPYGSRPVGDLEGVTSKLDYMTYEGHKTV YLTVNFIRVSGMVDGKPVEIERPIEFFMPAGQRSEGQQWITSTMRLLSMVARSGGSVAKALADMRNVVWDKGTVRYGTLA RQDGTEVPRFHDSEVAAIGYALQRILIKRGFLDAEGIQVPVAELAARLARRENGAAGAESGKGNTVAAAPVNPALGTGKP CPECGAHALHKVDGCAKCANCGYVGECG
Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides [H]
COG id: COG0209
COG function: function code F; Ribonucleotide reductase, alpha subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-cone domain [H]
Homologues:
Organism=Homo sapiens, GI4506749, Length=553, Percent_Identity=24.4122965641953, Blast_Score=147, Evalue=4e-35, Organism=Escherichia coli, GI2367133, Length=552, Percent_Identity=23.1884057971014, Blast_Score=96, Evalue=7e-21, Organism=Escherichia coli, GI1789030, Length=574, Percent_Identity=22.9965156794425, Blast_Score=92, Evalue=1e-19, Organism=Caenorhabditis elegans, GI17555242, Length=542, Percent_Identity=25.830258302583, Blast_Score=158, Evalue=1e-38, Organism=Saccharomyces cerevisiae, GI6322123, Length=583, Percent_Identity=24.6998284734134, Blast_Score=139, Evalue=2e-33, Organism=Saccharomyces cerevisiae, GI6320914, Length=553, Percent_Identity=24.4122965641953, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI17352481, Length=541, Percent_Identity=24.9537892791128, Blast_Score=154, Evalue=2e-37,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005144 - InterPro: IPR013344 - InterPro: IPR013509 - InterPro: IPR000788 - InterPro: IPR008926 [H]
Pfam domain/function: PF03477 ATP-cone; PF02867 Ribonuc_red_lgC; PF00317 Ribonuc_red_lgN [H]
EC number: =1.17.4.1 [H]
Molecular weight: Translated: 90313; Mature: 90313
Theoretical pI: Translated: 6.07; Mature: 6.07
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 2.7 %Met (Translated Protein) 4.3 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNANDQILRGALAPQEISTEVLLEKYAKGEEQSVTDVRKRVARALAQAETEDQREGWTAR CCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCEEE FLWAQESGFVPAGRINSAAGTGIQATLINCFVQPVGDSVSEPRGGRPSIYTAVAQAAETM EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH RRGGGVGYDFSAIRPAGALVRATHSRASGPVSFMKVFDASCATVESAGARRGAQMGVLRC HHCCCCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC DHPDIESFIHAKDKGDLSNFNISIGVTDEFMRAVERDEEVELVHEAEPGADLIAGGAYRR CCCCHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCCCEEEEECCCCCCCEEECCCEEC DDGQWVYRRMPARLLWDQVMHATYDHAEPGILFLSRINADNNLYYCETIEATNPCAEQPL CCCCHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCHHCCCC PPYGCCCLGSIDLTRFVRQPFTPDSDFDFDAFAEVVRVSTRMLDNVLDVTFWPLPEQQAE CCCCEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEECCCCHHHHH AQAKRRVGLGFLGLGSALVMLGLRYDSEPARVVAARIAERMRDEAYLASTELAAEKGAFP HHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC LFDADAYLQSGFASRLPEPVRQAIMRNGLRNSHLLSIAPTGTITLAFADNASNGIEPAFS EECCHHHHHCCHHHHCCHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHH WTYQRKKRMPDNTYRTYEVADHAWRRYRHTGADMNKLPDAFVTALQMSALDHMRMLQAVQ HHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHH PYIDTSISKTVNVPEDYPYEAFRNLYLEAWKAGLKGLATYRPNSVLGAVLSVSVPAVAAS HHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCC STATTVDDPLVRPYGSRPVGDLEGVTSKLDYMTYEGHKTVYLTVNFIRVSGMVDGKPVEI CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCEEEEEEEEEEEEECCCCCCCEEE ERPIEFFMPAGQRSEGQQWITSTMRLLSMVARSGGSVAKALADMRNVVWDKGTVRYGTLA CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCEE RQDGTEVPRFHDSEVAAIGYALQRILIKRGFLDAEGIQVPVAELAARLARRENGAAGAES CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC GKGNTVAAAPVNPALGTGKPCPECGAHALHKVDGCAKCANCGYVGECG CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC >Mature Secondary Structure MNANDQILRGALAPQEISTEVLLEKYAKGEEQSVTDVRKRVARALAQAETEDQREGWTAR CCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCEEE FLWAQESGFVPAGRINSAAGTGIQATLINCFVQPVGDSVSEPRGGRPSIYTAVAQAAETM EEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH RRGGGVGYDFSAIRPAGALVRATHSRASGPVSFMKVFDASCATVESAGARRGAQMGVLRC HHCCCCCCCCHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEC DHPDIESFIHAKDKGDLSNFNISIGVTDEFMRAVERDEEVELVHEAEPGADLIAGGAYRR CCCCHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCCCEEEEECCCCCCCEEECCCEEC DDGQWVYRRMPARLLWDQVMHATYDHAEPGILFLSRINADNNLYYCETIEATNPCAEQPL CCCCHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEEEEEECCCCCHHCCCC PPYGCCCLGSIDLTRFVRQPFTPDSDFDFDAFAEVVRVSTRMLDNVLDVTFWPLPEQQAE CCCCEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEECCCCHHHHH AQAKRRVGLGFLGLGSALVMLGLRYDSEPARVVAARIAERMRDEAYLASTELAAEKGAFP HHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC LFDADAYLQSGFASRLPEPVRQAIMRNGLRNSHLLSIAPTGTITLAFADNASNGIEPAFS EECCHHHHHCCHHHHCCHHHHHHHHHCCCCCCCEEEEECCCEEEEEEECCCCCCCCCHHH WTYQRKKRMPDNTYRTYEVADHAWRRYRHTGADMNKLPDAFVTALQMSALDHMRMLQAVQ HHHHHHHCCCCCCCEEHHHHHHHHHHHHHCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHH PYIDTSISKTVNVPEDYPYEAFRNLYLEAWKAGLKGLATYRPNSVLGAVLSVSVPAVAAS HHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHCCC STATTVDDPLVRPYGSRPVGDLEGVTSKLDYMTYEGHKTVYLTVNFIRVSGMVDGKPVEI CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCEEEEEEEEEEEEECCCCCCCEEE ERPIEFFMPAGQRSEGQQWITSTMRLLSMVARSGGSVAKALADMRNVVWDKGTVRYGTLA CCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEECCEE RQDGTEVPRFHDSEVAAIGYALQRILIKRGFLDAEGIQVPVAELAARLARRENGAAGAES CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC GKGNTVAAAPVNPALGTGKPCPECGAHALHKVDGCAKCANCGYVGECG CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9634230; 12218036 [H]