Click here to switch to the map view.

The map label for this gene is yphC [H]

Identifier: 73541514

GI number: 73541514

Start: 1999520

End: 2000575

Strand: Direct

Name: yphC [H]

Synonym: Reut_A1825

Alternate gene names: 73541514

Gene position: 1999520-2000575 (Clockwise)

Preceding gene: 73541513

Following gene: 73541515

Centisome position: 52.53

GC content: 69.13

Gene sequence:

>1056_bases
ATGCGCGGGATGATCTTCCGGGGCGCCCGCGAGGTCGAGCTGGCGCATTTCGATGACCCCACGCCCGGCCCCGGCGAGGC
CGTGATCGAGATGAAGGCGTCGGGCATGTGCGGCACCGATCTCCACTACTACCGGCATGGCATGGCGGCTTCGCTGGAGA
TGCTTGGCCTGAAGGACCGCATTACGTCCGACCGGATCATCGGCGGGCACGAGCCGTGCGGCGTGGTGGCTGCGCTCGGC
CCGGGCGTGGACAGCAAAGCGTTCCGCGTGGGCGACCGCGTAATGGTCTTCCACTACGAGGGCTGCCGCCACTGCGACCA
TTGCCGCACCGGCTGGACGCAGCTCTGCGACCACGGCGCGCGCATCCACGGCGTGCTGGCGCATGGCGGCCATGCCGATT
ACATGAAGGTGCCGGTGTCATCGCTGGTGCACCTGCCGCAGGAGATGTCGTTCGCGGGCGGCGCCGCCGTGGCATGCGGC
ACCGGCACCGCGTACGGCGCCTTGCTGCGGCTCGACATCAGCGCCCGCGACACGCTGGCCGTCTACGGCCTTGGCCCGGT
CGGCCTGTCGGTGGCCCAGCTTGCCGCCGCGATGGGCGTCGAGGTGTTCGGCGTCGACATCAGCGCAGCGCGCGTGACCC
GCGCGAAAGACTTCGGCGTGACACACGCGATCGACGCCACGCAGTCCGACCCGGTCGCAGAGATACTGAAGCTGACCGGG
GGCAAGGGCGCGTCGTGCGCGGTGGAGTGTGCCGGCGGCGAGCTGGCGCGCGCTCAGGCCGTGCGCAGCACCAGGGTGTG
GGGCCGCATCGCGCTGGTGGCCGTGGGCGGCAACCTGGTGCTCGATGCGATGAAGGATCTGATCGGCAAGCAGCGGCAGT
TGCTCGGCTCATTCACGTTCTCCGAAGTCGACATGAAGGCTTGCGCCAGCTTTATCGCCACACGGGGCATCGAGGTGGAC
CGGCTGTTCACCGACACCTGGCGACTCGACCAGGCCGCGCAGGCCTATGCCCACTTCGATCAGCAGGCGGGCGGCAAGGG
CGTGTTCCTGTTCTGA

Upstream 100 bases:

>100_bases
TCGTACTCGACGGCTGGTCGCACTATGACCTGTACGACAAGCCCGAGCCCGTGCGCAAGGCGCTCGACAAGCTGATCCCG
TTCTACAAGGAGCATCTCGG

Downstream 100 bases:

>100_bases
ATCCTGCCCCCCTTTTTCACGGTTGCAGCCGGCCCCGGCGGGCAACGGAGATCCATTCCATGACGAATCGAACTATCGAA
CTCAAGCACCCGCGCCAGCT

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRGMIFRGAREVELAHFDDPTPGPGEAVIEMKASGMCGTDLHYYRHGMAASLEMLGLKDRITSDRIIGGHEPCGVVAALG
PGVDSKAFRVGDRVMVFHYEGCRHCDHCRTGWTQLCDHGARIHGVLAHGGHADYMKVPVSSLVHLPQEMSFAGGAAVACG
TGTAYGALLRLDISARDTLAVYGLGPVGLSVAQLAAAMGVEVFGVDISAARVTRAKDFGVTHAIDATQSDPVAEILKLTG
GKGASCAVECAGGELARAQAVRSTRVWGRIALVAVGGNLVLDAMKDLIGKQRQLLGSFTFSEVDMKACASFIATRGIEVD
RLFTDTWRLDQAAQAYAHFDQQAGGKGVFLF

Sequences:

>Translated_351_residues
MRGMIFRGAREVELAHFDDPTPGPGEAVIEMKASGMCGTDLHYYRHGMAASLEMLGLKDRITSDRIIGGHEPCGVVAALG
PGVDSKAFRVGDRVMVFHYEGCRHCDHCRTGWTQLCDHGARIHGVLAHGGHADYMKVPVSSLVHLPQEMSFAGGAAVACG
TGTAYGALLRLDISARDTLAVYGLGPVGLSVAQLAAAMGVEVFGVDISAARVTRAKDFGVTHAIDATQSDPVAEILKLTG
GKGASCAVECAGGELARAQAVRSTRVWGRIALVAVGGNLVLDAMKDLIGKQRQLLGSFTFSEVDMKACASFIATRGIEVD
RLFTDTWRLDQAAQAYAHFDQQAGGKGVFLF
>Mature_351_residues
MRGMIFRGAREVELAHFDDPTPGPGEAVIEMKASGMCGTDLHYYRHGMAASLEMLGLKDRITSDRIIGGHEPCGVVAALG
PGVDSKAFRVGDRVMVFHYEGCRHCDHCRTGWTQLCDHGARIHGVLAHGGHADYMKVPVSSLVHLPQEMSFAGGAAVACG
TGTAYGALLRLDISARDTLAVYGLGPVGLSVAQLAAAMGVEVFGVDISAARVTRAKDFGVTHAIDATQSDPVAEILKLTG
GKGASCAVECAGGELARAQAVRSTRVWGRIALVAVGGNLVLDAMKDLIGKQRQLLGSFTFSEVDMKACASFIATRGIEVD
RLFTDTWRLDQAAQAYAHFDQQAGGKGVFLF

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=346, Percent_Identity=24.2774566473988, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI71565152, Length=375, Percent_Identity=25.6, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI4501929, Length=368, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI262073058, Length=370, Percent_Identity=23.2432432432432, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI71743840, Length=370, Percent_Identity=23.2432432432432, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=24.7282608695652, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI34577061, Length=356, Percent_Identity=25, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI4501939, Length=355, Percent_Identity=26.1971830985915, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI156523966, Length=355, Percent_Identity=26.1971830985915, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI71565154, Length=271, Percent_Identity=24.7232472324723, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI87082125, Length=354, Percent_Identity=35.8757062146893, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI1787863, Length=343, Percent_Identity=27.4052478134111, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI226510992, Length=353, Percent_Identity=26.0623229461756, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1790045, Length=261, Percent_Identity=27.9693486590038, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87081918, Length=294, Percent_Identity=30.6122448979592, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788075, Length=358, Percent_Identity=25.4189944134078, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788073, Length=325, Percent_Identity=25.8461538461538, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786825, Length=281, Percent_Identity=25.9786476868327, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786552, Length=294, Percent_Identity=25.8503401360544, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082401, Length=233, Percent_Identity=26.1802575107296, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790718, Length=321, Percent_Identity=24.2990654205607, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788407, Length=235, Percent_Identity=27.6595744680851, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17562876, Length=350, Percent_Identity=25.1428571428571, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71988145, Length=343, Percent_Identity=27.1137026239067, Blast_Score=105, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI17562584, Length=311, Percent_Identity=29.2604501607717, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17562878, Length=265, Percent_Identity=26.7924528301887, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI71997431, Length=315, Percent_Identity=23.8095238095238, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI25146526, Length=315, Percent_Identity=23.8095238095238, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=323, Percent_Identity=25.6965944272446, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565904, Length=247, Percent_Identity=25.5060728744939, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319955, Length=323, Percent_Identity=30.9597523219814, Blast_Score=142, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6322619, Length=323, Percent_Identity=30.9597523219814, Blast_Score=142, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6323099, Length=322, Percent_Identity=26.3975155279503, Blast_Score=110, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6324486, Length=323, Percent_Identity=28.7925696594427, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=322, Percent_Identity=29.1925465838509, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323729, Length=309, Percent_Identity=27.831715210356, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=311, Percent_Identity=27.3311897106109, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6319257, Length=350, Percent_Identity=24.8571428571429, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6319258, Length=287, Percent_Identity=25.7839721254355, Blast_Score=70, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6320033, Length=236, Percent_Identity=25.4237288135593, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17737897, Length=345, Percent_Identity=26.6666666666667, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17137530, Length=346, Percent_Identity=26.5895953757225, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI17737895, Length=283, Percent_Identity=26.8551236749117, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI45550770, Length=336, Percent_Identity=21.7261904761905, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI221457811, Length=336, Percent_Identity=21.7261904761905, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45551930, Length=336, Percent_Identity=21.7261904761905, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 37119; Mature: 37119

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGMIFRGAREVELAHFDDPTPGPGEAVIEMKASGMCGTDLHYYRHGMAASLEMLGLKDR
CCCCEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHCHHHHHHHHCCHHH
ITSDRIIGGHEPCGVVAALGPGVDSKAFRVGDRVMVFHYEGCRHCDHCRTGWTQLCDHGA
CCCCCCCCCCCCCCEEEEECCCCCCCCEEECCEEEEEEECCCCCHHHHHCCHHHHHCCCC
RIHGVLAHGGHADYMKVPVSSLVHLPQEMSFAGGAAVACGTGTAYGALLRLDISARDTLA
EEEEEEECCCCCCCEECCHHHHHHCCHHHCCCCCCEEEECCCCCCEEEEEEEECCCCEEE
VYGLGPVGLSVAQLAAAMGVEVFGVDISAARVTRAKDFGVTHAIDATQSDPVAEILKLTG
EEECCHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCC
GKGASCAVECAGGELARAQAVRSTRVWGRIALVAVGGNLVLDAMKDLIGKQRQLLGSFTF
CCCCCEEEEECCCHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCH
SEVDMKACASFIATRGIEVDRLFTDTWRLDQAAQAYAHFDQQAGGKGVFLF
HHHHHHHHHHHHHHCCCEEHHEEHHHHHHHHHHHHHHHHHHHCCCCEEEEC
>Mature Secondary Structure
MRGMIFRGAREVELAHFDDPTPGPGEAVIEMKASGMCGTDLHYYRHGMAASLEMLGLKDR
CCCCEECCCCEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHCHHHHHHHHCCHHH
ITSDRIIGGHEPCGVVAALGPGVDSKAFRVGDRVMVFHYEGCRHCDHCRTGWTQLCDHGA
CCCCCCCCCCCCCCEEEEECCCCCCCCEEECCEEEEEEECCCCCHHHHHCCHHHHHCCCC
RIHGVLAHGGHADYMKVPVSSLVHLPQEMSFAGGAAVACGTGTAYGALLRLDISARDTLA
EEEEEEECCCCCCCEECCHHHHHHCCHHHCCCCCCEEEECCCCCCEEEEEEEECCCCEEE
VYGLGPVGLSVAQLAAAMGVEVFGVDISAARVTRAKDFGVTHAIDATQSDPVAEILKLTG
EEECCHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHCC
GKGASCAVECAGGELARAQAVRSTRVWGRIALVAVGGNLVLDAMKDLIGKQRQLLGSFTF
CCCCCEEEEECCCHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCH
SEVDMKACASFIATRGIEVDRLFTDTWRLDQAAQAYAHFDQQAGGKGVFLF
HHHHHHHHHHHHHHCCCEEHHEEHHHHHHHHHHHHHHHHHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]