Click here to switch to the map view.

The map label for this gene is tftE [H]

Identifier: 73541279

GI number: 73541279

Start: 1712101

End: 1713168

Strand: Direct

Name: tftE [H]

Synonym: Reut_A1589

Alternate gene names: 73541279

Gene position: 1712101-1713168 (Clockwise)

Preceding gene: 73541278

Following gene: 73541280

Centisome position: 44.98

GC content: 66.57

Gene sequence:

>1068_bases
ATGAAAGCATTCCAGTACGCCGCGCGCGCCCAGCGCATCGTCTTTGGCGCCGGCACGATCCGGCAAGTCGGCGAGGAAAT
CGATGCACTGGGCGCATCCAGTGTCCTGGTGCTCAGCACCCCCGAGCAGCGCCGGCTGGCCGAACAGGTGTCGGACCTGC
TTGGCGCCCGCGCGATCGGCATCTTTGACCGCGCCGTGATGCACGTGCCGGTCGAGACGGCGCGCGCGGCCTGCGCGATG
GCATTCGAGCTGGGCGCCGACAGCGTGGTGGCGATCGGTGGCGGCTCCACGACGGGGCTCGCCAAGGCCATCGCCCTCGA
GATGAGCGTGCCCGTGCTGGCGATTCCCACCACCTATGCCGGCTCGGAGATGACTACGATATACGGCCTCACCGATGCGG
GCCTGAAGCGTACTGGGACTGACGTGCGAGTGCTGCCGCGCACTGTCATCTACGATCCTGAACTGACCTACTTGCTGCCG
GCGGCGATCAGCGTGACCAGCGGCATCAACGCACTCGCGCACGCAGCAGAAGGTTTGTACGCCCATGACCGCAACCCGAT
TTCGGACCTGATGGCAAGGGAAGGCATTCAGGCCATGGCGGCGGCGCTGCCCGCGCTCGTCAGCGAACGGGATACCGCCA
GGTTGCGCGAGGCGCGCGCGCAAGCCCTGTATGGCGCGTGGTTATGCGGAGCAGTGCTTGGCAGTGTGGGGGTGGCGTTG
CATCACAAGCTCTGCCACACGCTTGGAGGCAGCTTCAACCTGCCGCATGCGGAAACGCACACGATCATCCTGCCGCACGC
GCTGGCCTACAACGCGAAGGCTGCGCCGGACGCCATGGCCTCCATCGCGCAGGCCCTGGGCGCAGACAATGCGGCACAAG
GAGCTTTCGACCTGGCGCGCACGACCGGTGCGCCGTTGGGGTTGCGCCAGATCGGCATGCGCGAGGACGAACTCGACAAG
GCTTGCGAGATCGCGCTGCAGAACCAGTACCCGAACCCGCGTCCGCTTGAAGCTGGGGCGATCCGTGAATTGCTGCAGAA
CGCGTGGGAGGGGCGTCGGCCCGTTTGA

Upstream 100 bases:

>100_bases
TCTCGCTTAAAGGGCAGTTCGAGTTCGGCGCCCGCAATCGGCCGGAAGGCAACCGGATCTGGGCCATGGGCCGCATATCG
TTTTGACGGGAGACCCTACG

Downstream 100 bases:

>100_bases
AGCGGTATGTGTTGGTGGCGCGCGATCAGTTCGCGCTCAGGGGGCAAACAACGGAAGGCACAAAATGTGGAAGGTTCCAA
AGCAATACAGCCATTTTGCG

Product: Iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKAFQYAARAQRIVFGAGTIRQVGEEIDALGASSVLVLSTPEQRRLAEQVSDLLGARAIGIFDRAVMHVPVETARAACAM
AFELGADSVVAIGGGSTTGLAKAIALEMSVPVLAIPTTYAGSEMTTIYGLTDAGLKRTGTDVRVLPRTVIYDPELTYLLP
AAISVTSGINALAHAAEGLYAHDRNPISDLMAREGIQAMAAALPALVSERDTARLREARAQALYGAWLCGAVLGSVGVAL
HHKLCHTLGGSFNLPHAETHTIILPHALAYNAKAAPDAMASIAQALGADNAAQGAFDLARTTGAPLGLRQIGMREDELDK
ACEIALQNQYPNPRPLEAGAIRELLQNAWEGRRPV

Sequences:

>Translated_355_residues
MKAFQYAARAQRIVFGAGTIRQVGEEIDALGASSVLVLSTPEQRRLAEQVSDLLGARAIGIFDRAVMHVPVETARAACAM
AFELGADSVVAIGGGSTTGLAKAIALEMSVPVLAIPTTYAGSEMTTIYGLTDAGLKRTGTDVRVLPRTVIYDPELTYLLP
AAISVTSGINALAHAAEGLYAHDRNPISDLMAREGIQAMAAALPALVSERDTARLREARAQALYGAWLCGAVLGSVGVAL
HHKLCHTLGGSFNLPHAETHTIILPHALAYNAKAAPDAMASIAQALGADNAAQGAFDLARTTGAPLGLRQIGMREDELDK
ACEIALQNQYPNPRPLEAGAIRELLQNAWEGRRPV
>Mature_355_residues
MKAFQYAARAQRIVFGAGTIRQVGEEIDALGASSVLVLSTPEQRRLAEQVSDLLGARAIGIFDRAVMHVPVETARAACAM
AFELGADSVVAIGGGSTTGLAKAIALEMSVPVLAIPTTYAGSEMTTIYGLTDAGLKRTGTDVRVLPRTVIYDPELTYLLP
AAISVTSGINALAHAAEGLYAHDRNPISDLMAREGIQAMAAALPALVSERDTARLREARAQALYGAWLCGAVLGSVGVAL
HHKLCHTLGGSFNLPHAETHTIILPHALAYNAKAAPDAMASIAQALGADNAAQGAFDLARTTGAPLGLRQIGMREDELDK
ACEIALQNQYPNPRPLEAGAIRELLQNAWEGRRPV

Specific function: Fucose metabolism; fourth step. [C]

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1789163, Length=376, Percent_Identity=28.9893617021277, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI48994951, Length=361, Percent_Identity=27.9778393351801, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI87082107, Length=233, Percent_Identity=31.7596566523605, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787493, Length=378, Percent_Identity=23.2804232804233, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=425, Percent_Identity=23.5294117647059, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6321181, Length=371, Percent_Identity=26.4150943396226, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24657991, Length=390, Percent_Identity=25.3846153846154, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.3.1.32 [H]

Molecular weight: Translated: 37315; Mature: 37315

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAFQYAARAQRIVFGAGTIRQVGEEIDALGASSVLVLSTPEQRRLAEQVSDLLGARAIG
CCHHHHHHHHHEEEECCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
IFDRAVMHVPVETARAACAMAFELGADSVVAIGGGSTTGLAKAIALEMSVPVLAIPTTYA
HHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCC
GSEMTTIYGLTDAGLKRTGTDVRVLPRTVIYDPELTYLLPAAISVTSGINALAHAAEGLY
CCCCEEEEECCCCCCCCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
AHDRNPISDLMAREGIQAMAAALPALVSERDTARLREARAQALYGAWLCGAVLGSVGVAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHKLCHTLGGSFNLPHAETHTIILPHALAYNAKAAPDAMASIAQALGADNAAQGAFDLAR
HHHHHHHCCCCCCCCCCCCCEEEECHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
TTGAPLGLRQIGMREDELDKACEIALQNQYPNPRPLEAGAIRELLQNAWEGRRPV
HCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKAFQYAARAQRIVFGAGTIRQVGEEIDALGASSVLVLSTPEQRRLAEQVSDLLGARAIG
CCHHHHHHHHHEEEECCHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHH
IFDRAVMHVPVETARAACAMAFELGADSVVAIGGGSTTGLAKAIALEMSVPVLAIPTTYA
HHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCEEEECCCCC
GSEMTTIYGLTDAGLKRTGTDVRVLPRTVIYDPELTYLLPAAISVTSGINALAHAAEGLY
CCCCEEEEECCCCCCCCCCCCEEEECCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCC
AHDRNPISDLMAREGIQAMAAALPALVSERDTARLREARAQALYGAWLCGAVLGSVGVAL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HHKLCHTLGGSFNLPHAETHTIILPHALAYNAKAAPDAMASIAQALGADNAAQGAFDLAR
HHHHHHHCCCCCCCCCCCCCEEEECHHHHCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHH
TTGAPLGLRQIGMREDELDKACEIALQNQYPNPRPLEAGAIRELLQNAWEGRRPV
HCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7538273 [H]