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The map label for this gene is msrB [H]

Identifier: 73541089

GI number: 73541089

Start: 1508666

End: 1509076

Strand: Reverse

Name: msrB [H]

Synonym: Reut_A1395

Alternate gene names: 73541089

Gene position: 1509076-1508666 (Counterclockwise)

Preceding gene: 73541090

Following gene: 161611261

Centisome position: 39.64

GC content: 63.99

Gene sequence:

>411_bases
ATGACCACAAGCAAGACCGAAGCCGAGTGGCGCGAGCAACTCTCCGACATCGAATACCGCGTCACACGCGAGGCCGCGAC
CGAGCGCCCGTTCACGGGCCGCTACTGGGATCACTGGGACAACGGCATCTACAAATGCGTTGGCTGTGGGACGCCGCTGT
TCGAATCGGCCACCAAGTTTGACGCCGGCTGCGGCTGGCCCAGCTACTTCCGGCCCATCAACGGCGAAGTGATTGCCGAG
CACGCCGACCACACGCACGGCATGGTGCGCGTCGAGGTCCGTTGCAAGGAATGCGGCAGCCATCTGGGCCATGTATTCGA
AGATGGCCCCGCGCCGACCGGGCTGCGCTATTGCATCAACTCGGCTGCGCTAAAATTCGACGATCGCGACCCGGCTGAGC
GCGACGGCTGA

Upstream 100 bases:

>100_bases
CGCCGGCACACTTGCCGGCGCTGATGTAAGGTTCGGGCCACGGCCGCGACCAATGCGTGAGGCCGGCAGGAACGCCAGCC
CCCTACCGAAAGGATTGAGC

Downstream 100 bases:

>100_bases
CGCACATGCGCCTGGCCCGTGCAGCCGGCCCGCGGGCCAGGCACGCTGCCAGGCCCGCCAACCAGAATCATTCCTGCATG
AAATTCCTGTTCGACCTGTT

Product: methionine sulfoxide reductase B

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 136; Mature: 135

Protein sequence:

>136_residues
MTTSKTEAEWREQLSDIEYRVTREAATERPFTGRYWDHWDNGIYKCVGCGTPLFESATKFDAGCGWPSYFRPINGEVIAE
HADHTHGMVRVEVRCKECGSHLGHVFEDGPAPTGLRYCINSAALKFDDRDPAERDG

Sequences:

>Translated_136_residues
MTTSKTEAEWREQLSDIEYRVTREAATERPFTGRYWDHWDNGIYKCVGCGTPLFESATKFDAGCGWPSYFRPINGEVIAE
HADHTHGMVRVEVRCKECGSHLGHVFEDGPAPTGLRYCINSAALKFDDRDPAERDG
>Mature_135_residues
TTSKTEAEWREQLSDIEYRVTREAATERPFTGRYWDHWDNGIYKCVGCGTPLFESATKFDAGCGWPSYFRPINGEVIAEH
ADHTHGMVRVEVRCKECGSHLGHVFEDGPAPTGLRYCINSAALKFDDRDPAERDG

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=131, Percent_Identity=55.7251908396947, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI301336162, Length=131, Percent_Identity=55.7251908396947, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI73089054, Length=131, Percent_Identity=55.7251908396947, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI37620216, Length=125, Percent_Identity=56.8, Blast_Score=154, Evalue=2e-38,
Organism=Homo sapiens, GI117606353, Length=132, Percent_Identity=45.4545454545455, Blast_Score=120, Evalue=5e-28,
Organism=Homo sapiens, GI7706511, Length=93, Percent_Identity=35.4838709677419, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788077, Length=133, Percent_Identity=48.1203007518797, Blast_Score=147, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17553450, Length=126, Percent_Identity=49.2063492063492, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI115532676, Length=126, Percent_Identity=49.2063492063492, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6319816, Length=132, Percent_Identity=38.6363636363636, Blast_Score=108, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24645799, Length=125, Percent_Identity=49.6, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI45553335, Length=125, Percent_Identity=49.6, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI21356369, Length=125, Percent_Identity=49.6, Blast_Score=140, Evalue=2e-34,
Organism=Drosophila melanogaster, GI221378664, Length=119, Percent_Identity=49.5798319327731, Blast_Score=137, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24645801, Length=136, Percent_Identity=45.5882352941176, Blast_Score=136, Evalue=4e-33,
Organism=Drosophila melanogaster, GI24645804, Length=136, Percent_Identity=45.5882352941176, Blast_Score=136, Evalue=4e-33,
Organism=Drosophila melanogaster, GI221378662, Length=126, Percent_Identity=47.6190476190476, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15387; Mature: 15256

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTSKTEAEWREQLSDIEYRVTREAATERPFTGRYWDHWDNGIYKCVGCGTPLFESATKF
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCC
DAGCGWPSYFRPINGEVIAEHADHTHGMVRVEVRCKECGSHLGHVFEDGPAPTGLRYCIN
CCCCCCHHHCCCCCCEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHH
SAALKFDDRDPAERDG
HHHEECCCCCCCCCCC
>Mature Secondary Structure 
TTSKTEAEWREQLSDIEYRVTREAATERPFTGRYWDHWDNGIYKCVGCGTPLFESATKF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHCC
DAGCGWPSYFRPINGEVIAEHADHTHGMVRVEVRCKECGSHLGHVFEDGPAPTGLRYCIN
CCCCCCHHHCCCCCCEEEECCCCCCCCEEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHH
SAALKFDDRDPAERDG
HHHEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]