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The map label for this gene is surA [C]

Identifier: 73541086

GI number: 73541086

Start: 1506870

End: 1507664

Strand: Reverse

Name: surA [C]

Synonym: Reut_A1392

Alternate gene names: 73541086

Gene position: 1507664-1506870 (Counterclockwise)

Preceding gene: 73541087

Following gene: 73541085

Centisome position: 39.61

GC content: 61.76

Gene sequence:

>795_bases
ATGAAGACCACCGTCCTCTCGTTCAGCCTGGCGGCTGTGCTCGCTGCCGGCAGCCTGCCCGCAGCCGCCCAGAATGCCGC
TGTCGTGAATGGCAAGGCCATTCCCTCGGCCAAGCTGGACAAGCTGATCGCCGGCACCGGCCAGCCCGCCAACCCGGAAC
TGCGGGACCGTGCGCGCAGCATGCTGATCGACCGCGAACTGCTGGTGCAGGAAGCCAACAAGCGCGGCCTGACCCAGCGC
GACGACATTCAGGAGCAACTGGAACAGGCCCGCCTGAACGTGCTCGCCGGCGCGGTGTTCGAAGACTACGTCAAAACCCA
CGGCGCCAGCGACGACGAACTGCGCAAGCAGTACGACAAGATCAAGTCGCAGTTCGGCAACGGAAAGGAATACCACGTCC
GCCACATCCTGGTGGAAAAGGAAGCCGACGCCAAGGCCATCATCGCCAAGATCAAGGGCGGCGCGAAGTTCGAGGACATG
GCCAAGGCCTCGTCCAAGGACCCGGGTTCGGCTGCCAATGGCGGTGACCTCGACTGGGCCAACAGCGGTAGCTACGTGCC
GGAATTTTCTGCGGCTATGACTACCCTGAAGAAGGGTCAGATGACCGATACGCCGGTCAAGACTCAATTCGGCTGGCACA
TCATCGAGCTCGTCGACACCCGCGACGCGAAGATCCCGAGCTTCGAAGAGGTCAAACCGCAGCTCATGCAGATGATGATG
GGCGACCAGAACTGGCAGCGCGAACAGTTCCAGGCCATGATGAAGTCCCTCAAGGACAAGGCCAAGATCCAGTAA

Upstream 100 bases:

>100_bases
ACGCAGATCCACGCTTTGGCCGTGACCGCGTTCACCGATCAAGAATTTCAATCCCGCGAAACTTCACGCGGTTCTTCCAG
CAACTCTCAGACCTGATTCC

Downstream 100 bases:

>100_bases
CGTTGCAGGCCGGTACCCCCGCCGGGCTGCAGACTAGAAGGAAGCAGCAGCGTGGAGCCACAGACCGGCTACTGGCAACT
CTGGCACCTCTCTTCCCGGG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MKTTVLSFSLAAVLAAGSLPAAAQNAAVVNGKAIPSAKLDKLIAGTGQPANPELRDRARSMLIDRELLVQEANKRGLTQR
DDIQEQLEQARLNVLAGAVFEDYVKTHGASDDELRKQYDKIKSQFGNGKEYHVRHILVEKEADAKAIIAKIKGGAKFEDM
AKASSKDPGSAANGGDLDWANSGSYVPEFSAAMTTLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLMQMMM
GDQNWQREQFQAMMKSLKDKAKIQ

Sequences:

>Translated_264_residues
MKTTVLSFSLAAVLAAGSLPAAAQNAAVVNGKAIPSAKLDKLIAGTGQPANPELRDRARSMLIDRELLVQEANKRGLTQR
DDIQEQLEQARLNVLAGAVFEDYVKTHGASDDELRKQYDKIKSQFGNGKEYHVRHILVEKEADAKAIIAKIKGGAKFEDM
AKASSKDPGSAANGGDLDWANSGSYVPEFSAAMTTLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLMQMMM
GDQNWQREQFQAMMKSLKDKAKIQ
>Mature_264_residues
MKTTVLSFSLAAVLAAGSLPAAAQNAAVVNGKAIPSAKLDKLIAGTGQPANPELRDRARSMLIDRELLVQEANKRGLTQR
DDIQEQLEQARLNVLAGAVFEDYVKTHGASDDELRKQYDKIKSQFGNGKEYHVRHILVEKEADAKAIIAKIKGGAKFEDM
AKASSKDPGSAANGGDLDWANSGSYVPEFSAAMTTLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLMQMMM
GDQNWQREQFQAMMKSLKDKAKIQ

Specific function: Assist In The Folding Of Extracytoplasmic Proteins. Essential For The Survival Of E.Coli In Stationary Phase. [C]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Homo sapiens, GI38679892, Length=101, Percent_Identity=40.5940594059406, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1786238, Length=103, Percent_Identity=47.5728155339806, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1786645, Length=168, Percent_Identity=29.7619047619048, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17537235, Length=95, Percent_Identity=43.1578947368421, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356303, Length=94, Percent_Identity=40.4255319148936, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 29006; Mature: 29006

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTVLSFSLAAVLAAGSLPAAAQNAAVVNGKAIPSAKLDKLIAGTGQPANPELRDRARS
CCCCHHHHHHHHHHHHCCCCCHHCCCEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
MLIDRELLVQEANKRGLTQRDDIQEQLEQARLNVLAGAVFEDYVKTHGASDDELRKQYDK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IKSQFGNGKEYHVRHILVEKEADAKAIIAKIKGGAKFEDMAKASSKDPGSAANGGDLDWA
HHHHCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
NSGSYVPEFSAAMTTLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLMQMMM
CCCCCCCHHHHHHHHHHCCCCCCCCCCHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
GDQNWQREQFQAMMKSLKDKAKIQ
CCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKTTVLSFSLAAVLAAGSLPAAAQNAAVVNGKAIPSAKLDKLIAGTGQPANPELRDRARS
CCCCHHHHHHHHHHHHCCCCCHHCCCEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHH
MLIDRELLVQEANKRGLTQRDDIQEQLEQARLNVLAGAVFEDYVKTHGASDDELRKQYDK
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
IKSQFGNGKEYHVRHILVEKEADAKAIIAKIKGGAKFEDMAKASSKDPGSAANGGDLDWA
HHHHCCCCCEEEEEEEEEECCCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCCCCC
NSGSYVPEFSAAMTTLKKGQMTDTPVKTQFGWHIIELVDTRDAKIPSFEEVKPQLMQMMM
CCCCCCCHHHHHHHHHHCCCCCCCCCCHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHH
GDQNWQREQFQAMMKSLKDKAKIQ
CCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]