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The map label for this gene is crtB [H]

Identifier: 73541065

GI number: 73541065

Start: 1475131

End: 1476039

Strand: Reverse

Name: crtB [H]

Synonym: Reut_A1371

Alternate gene names: 73541065

Gene position: 1476039-1475131 (Counterclockwise)

Preceding gene: 73541071

Following gene: 73541064

Centisome position: 38.78

GC content: 66.12

Gene sequence:

>909_bases
ATGCTACAATCCCGCCGCCGCCAGGCTCTGACGCCGCCCGCACCCACCCTACCTCACCAGACCGAGACCGGCGTGACGCC
CGATCAGTATTGCCAAGAGAAAGTCGCCCAGAGCGGCTCCAGTTTCTACTACAGCTTCCTGTTCCTGCCCGCCGAACGCC
GCCGCGCGATCACGGCGCTTTATGCCTGGTGCCGCGAAGTCGACGATGTGGTCGACGACGCCCACGACCCCGCCCTGGCC
CACCAGCAACTGGACTGGTGGCGCGGTGAGCTGCGTCACCTGTTTGAAGGTGAGCCGACCCACCCCGTCACGCAGGCACT
GCGCCCGCACGTGAAGGCCGCCGGACTGCCGCATGCCGAAATGTCGGAAGTACTCGACGGCATGGAGATGGACCTGACCC
AGAGCCGGTATCTCGACGAGATCGGCCTGAACCGCTATTGCCACTGCGTGGCCGGCGTGGTCGGCACACTGAGCGCGCGG
CTGTTCGGCTATTCGGATCCCCACACGCTGGTATTCGCCGAGAAGCTCGGGCTGTCGCTGCAACTCGTCAATATCCTGCG
CGATGTCGGCGAGGACGCGCGCCGCGGCCGTATATATCTGCCTGTCGATACATTGCAGCGCTTCCAGGTGCCCGCGTCGG
AAATCCTCCAGGGCAAGCATTCCGAGCGCTTTGTCGCGCTGATGCAGTACCACGCTGGGCGCGCCCGCGCGCTGTACCGC
GAGGCGCTGGACCTGCTGCCGCGCCAAGATCGCCGCGCCCAGCGCGCAGGCCTGCTGATGGGCGCCATCTACCACGCGCT
GCTCGACGAGATCGAGCGCAGCGACTTCCAGGTGCTGAACCAGCGCATTGCGCTCACGCCGCTGCGCAAGCTCTGGATCG
CCTGGAAGACCTGGGTGCGCAACAGCTAG

Upstream 100 bases:

>100_bases
TGAAGACCGAAGCTTCCTTCTAGACCGCGGAACGGCACGAAATGGCGGCCGGCGCTGTCTGGGTGTGAGCTCAAGCAGCA
CCGGAAACTGCTATGGCTCA

Downstream 100 bases:

>100_bases
CCCCCAAAGCCATTCCCGCCCTGCACCACGCCGTTCGCCAAGCCATGACCCAGAATTCCCATCCGCTCGGACAGAGCATC
ATTGACCGCGCCGAAGCGCT

Product: squalene/phytoene synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MLQSRRRQALTPPAPTLPHQTETGVTPDQYCQEKVAQSGSSFYYSFLFLPAERRRAITALYAWCREVDDVVDDAHDPALA
HQQLDWWRGELRHLFEGEPTHPVTQALRPHVKAAGLPHAEMSEVLDGMEMDLTQSRYLDEIGLNRYCHCVAGVVGTLSAR
LFGYSDPHTLVFAEKLGLSLQLVNILRDVGEDARRGRIYLPVDTLQRFQVPASEILQGKHSERFVALMQYHAGRARALYR
EALDLLPRQDRRAQRAGLLMGAIYHALLDEIERSDFQVLNQRIALTPLRKLWIAWKTWVRNS

Sequences:

>Translated_302_residues
MLQSRRRQALTPPAPTLPHQTETGVTPDQYCQEKVAQSGSSFYYSFLFLPAERRRAITALYAWCREVDDVVDDAHDPALA
HQQLDWWRGELRHLFEGEPTHPVTQALRPHVKAAGLPHAEMSEVLDGMEMDLTQSRYLDEIGLNRYCHCVAGVVGTLSAR
LFGYSDPHTLVFAEKLGLSLQLVNILRDVGEDARRGRIYLPVDTLQRFQVPASEILQGKHSERFVALMQYHAGRARALYR
EALDLLPRQDRRAQRAGLLMGAIYHALLDEIERSDFQVLNQRIALTPLRKLWIAWKTWVRNS
>Mature_302_residues
MLQSRRRQALTPPAPTLPHQTETGVTPDQYCQEKVAQSGSSFYYSFLFLPAERRRAITALYAWCREVDDVVDDAHDPALA
HQQLDWWRGELRHLFEGEPTHPVTQALRPHVKAAGLPHAEMSEVLDGMEMDLTQSRYLDEIGLNRYCHCVAGVVGTLSAR
LFGYSDPHTLVFAEKLGLSLQLVNILRDVGEDARRGRIYLPVDTLQRFQVPASEILQGKHSERFVALMQYHAGRARALYR
EALDLLPRQDRRAQRAGLLMGAIYHALLDEIERSDFQVLNQRIALTPLRKLWIAWKTWVRNS

Specific function: Catalyzes the reaction from prephytoene diphosphate to phytoene [H]

COG id: COG1562

COG function: function code I; Phytoene/squalene synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phytoene/squalene synthase family [H]

Homologues:

Organism=Homo sapiens, GI124517691, Length=274, Percent_Identity=23.3576642335766, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002060
- InterPro:   IPR019845
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00494 SQS_PSY [H]

EC number: =2.5.1.32 [H]

Molecular weight: Translated: 34561; Mature: 34561

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS01044 SQUALEN_PHYTOEN_SYN_1 ; PS01045 SQUALEN_PHYTOEN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQSRRRQALTPPAPTLPHQTETGVTPDQYCQEKVAQSGSSFYYSFLFLPAERRRAITAL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHEECCHHHHHHHHHH
YAWCREVDDVVDDAHDPALAHQQLDWWRGELRHLFEGEPTHPVTQALRPHVKAAGLPHAE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHH
MSEVLDGMEMDLTQSRYLDEIGLNRYCHCVAGVVGTLSARLFGYSDPHTLVFAEKLGLSL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCHH
QLVNILRDVGEDARRGRIYLPVDTLQRFQVPASEILQGKHSERFVALMQYHAGRARALYR
HHHHHHHHHCHHHHCCEEEEEHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCHHHHHHHH
EALDLLPRQDRRAQRAGLLMGAIYHALLDEIERSDFQVLNQRIALTPLRKLWIAWKTWVR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NS
CC
>Mature Secondary Structure
MLQSRRRQALTPPAPTLPHQTETGVTPDQYCQEKVAQSGSSFYYSFLFLPAERRRAITAL
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEHHEECCHHHHHHHHHH
YAWCREVDDVVDDAHDPALAHQQLDWWRGELRHLFEGEPTHPVTQALRPHVKAAGLPHAE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCHHH
MSEVLDGMEMDLTQSRYLDEIGLNRYCHCVAGVVGTLSARLFGYSDPHTLVFAEKLGLSL
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCHH
QLVNILRDVGEDARRGRIYLPVDTLQRFQVPASEILQGKHSERFVALMQYHAGRARALYR
HHHHHHHHHCHHHHCCEEEEEHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHCHHHHHHHH
EALDLLPRQDRRAQRAGLLMGAIYHALLDEIERSDFQVLNQRIALTPLRKLWIAWKTWVR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA