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The map label for this gene is argE [H]

Identifier: 73541053

GI number: 73541053

Start: 1461069

End: 1462283

Strand: Reverse

Name: argE [H]

Synonym: Reut_A1359

Alternate gene names: 73541053

Gene position: 1462283-1461069 (Counterclockwise)

Preceding gene: 73541054

Following gene: 73541052

Centisome position: 38.42

GC content: 65.93

Gene sequence:

>1215_bases
ATGCAAGCCGATACTCAACGCCAGTCTTCAGCCACTGAAGCCAATGCGCCGCGCGGCAGCGCGATCGAATGGACGCAGCG
CCTGGTGGCGTACGACACCACGAGCCGCCATTCCAACCTGGGGCTGATCGAGTCCGTACGCGACCACTTCCTCGCGAAGG
GCTTGCGACCCCATCTGAGCTACAACCCCCAGCAAGACAAGGCCAACCTGTTCGTCACGGTGCCGGCCGCCAGCGGCGAC
ACCAATGGCGGCATCGTGCTGTCGGGCCACACCGACGTGGTGCCCGTGGACGGCCAGAACTGGACCACGGACCCGTTCAA
GCCGGTGGTGCGCGACGGCAAGCTCTATGGCCGCGGTACGTGTGACATGAAGGGCTTTATCGGCACCAGCCTGGCGCTGC
TGCCGACGCTGCTCGACGCGAAGCTGCGCGAGCCCGTGCACTATGCGCTGTCGTTCGACGAGGAGATCGGCTGCATGGGC
GCGCCCTACCTGCTTGCCGAACTCCGTGAGCGCGGCGTGCGCCCGGCCGGCTGCATCGTGGGCGAGCCCACCAGCATGCG
CGTGATCGTCGCACACAAGGGCATCAACGCGTACCGGTGCTGCGTCAAGGGTCATGCCGCACATTCGTCGCTGACGCCCC
GCGGTGTCAACGCGATCGAATACGCGGCGCGGCTGATTTGCTTCATCCGCGACATTGCCGACGAGTTCAAGGCCAACGGC
CCGTACGACAAGGCCTTCGACGTGCCTTACACCACCGCGCAGACCGGCACGATCCAGGGCGGCATCGCGCTGAATACCAT
TCCGGCGCTGTGCGAATTCGTATTCGAGTTCCGCAACCTGCCCGGCGTGGATCCCGAAGCGCTGTTCGCGCGGATCCAGT
CGTATGCCAATGACGTACTGCTGCCGAAGATGCGCGCCGAACACGCCGATGCCGGCCTTGTGATCAGCAAAATCGCGGCG
GCACCGTCGCTCGACGCCGCCGAGCAGGAAGCCATCACGCAACTGGTGCGCGCGCTGACTGGCGACCGCGAGACCAGCAA
GGTTGCCTACGGCACCGAGGCCGGGCTGTTCCAGCGCGCGGGGATTCCCGCGGTGGTATGCGGCCCCGGCGATATCGAGC
AGGCGCACAAGCCGGATGAGTTTGTCGCGCTCGATCAGCTTGTCGCTTGCGAGGCGTTCCTGCGCAAGGTCGTCGACAGC
CTGCGCGTGGCCTGA

Upstream 100 bases:

>100_bases
CGCCAGCTGGCATAGGGAATTTGCTGCAGGCGTCTTACCCGAGGGGCCGGGACGGGTGTAGCATCAGCTACTTCACCCGT
CGTTCAGAGCCCCCTGCCCC

Downstream 100 bases:

>100_bases
CCCACCCTTTTCGCCGTGCGCTGCTTCCCTCTCCAATTGCGAGAGGGAAGCGGCCACTCGGCTTTCCTGGCGCATCGCAG
CGCCAAGACACCACCAGCCT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MQADTQRQSSATEANAPRGSAIEWTQRLVAYDTTSRHSNLGLIESVRDHFLAKGLRPHLSYNPQQDKANLFVTVPAASGD
TNGGIVLSGHTDVVPVDGQNWTTDPFKPVVRDGKLYGRGTCDMKGFIGTSLALLPTLLDAKLREPVHYALSFDEEIGCMG
APYLLAELRERGVRPAGCIVGEPTSMRVIVAHKGINAYRCCVKGHAAHSSLTPRGVNAIEYAARLICFIRDIADEFKANG
PYDKAFDVPYTTAQTGTIQGGIALNTIPALCEFVFEFRNLPGVDPEALFARIQSYANDVLLPKMRAEHADAGLVISKIAA
APSLDAAEQEAITQLVRALTGDRETSKVAYGTEAGLFQRAGIPAVVCGPGDIEQAHKPDEFVALDQLVACEAFLRKVVDS
LRVA

Sequences:

>Translated_404_residues
MQADTQRQSSATEANAPRGSAIEWTQRLVAYDTTSRHSNLGLIESVRDHFLAKGLRPHLSYNPQQDKANLFVTVPAASGD
TNGGIVLSGHTDVVPVDGQNWTTDPFKPVVRDGKLYGRGTCDMKGFIGTSLALLPTLLDAKLREPVHYALSFDEEIGCMG
APYLLAELRERGVRPAGCIVGEPTSMRVIVAHKGINAYRCCVKGHAAHSSLTPRGVNAIEYAARLICFIRDIADEFKANG
PYDKAFDVPYTTAQTGTIQGGIALNTIPALCEFVFEFRNLPGVDPEALFARIQSYANDVLLPKMRAEHADAGLVISKIAA
APSLDAAEQEAITQLVRALTGDRETSKVAYGTEAGLFQRAGIPAVVCGPGDIEQAHKPDEFVALDQLVACEAFLRKVVDS
LRVA
>Mature_404_residues
MQADTQRQSSATEANAPRGSAIEWTQRLVAYDTTSRHSNLGLIESVRDHFLAKGLRPHLSYNPQQDKANLFVTVPAASGD
TNGGIVLSGHTDVVPVDGQNWTTDPFKPVVRDGKLYGRGTCDMKGFIGTSLALLPTLLDAKLREPVHYALSFDEEIGCMG
APYLLAELRERGVRPAGCIVGEPTSMRVIVAHKGINAYRCCVKGHAAHSSLTPRGVNAIEYAARLICFIRDIADEFKANG
PYDKAFDVPYTTAQTGTIQGGIALNTIPALCEFVFEFRNLPGVDPEALFARIQSYANDVLLPKMRAEHADAGLVISKIAA
APSLDAAEQEAITQLVRALTGDRETSKVAYGTEAGLFQRAGIPAVVCGPGDIEQAHKPDEFVALDQLVACEAFLRKVVDS
LRVA

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790395, Length=376, Percent_Identity=34.5744680851064, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1788816, Length=338, Percent_Identity=27.810650887574, Blast_Score=82, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17551016, Length=349, Percent_Identity=26.9340974212034, Blast_Score=79, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 43531; Mature: 43531

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQADTQRQSSATEANAPRGSAIEWTQRLVAYDTTSRHSNLGLIESVRDHFLAKGLRPHLS
CCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
YNPQQDKANLFVTVPAASGDTNGGIVLSGHTDVVPVDGQNWTTDPFKPVVRDGKLYGRGT
CCCCCCCCCEEEEEECCCCCCCCCEEEECCCCEEECCCCCCCCCCCHHHHHCCCEECCCC
CDMKGFIGTSLALLPTLLDAKLREPVHYALSFDEEIGCMGAPYLLAELRERGVRPAGCIV
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEE
GEPTSMRVIVAHKGINAYRCCVKGHAAHSSLTPRGVNAIEYAARLICFIRDIADEFKANG
CCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PYDKAFDVPYTTAQTGTIQGGIALNTIPALCEFVFEFRNLPGVDPEALFARIQSYANDVL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
LPKMRAEHADAGLVISKIAAAPSLDAAEQEAITQLVRALTGDRETSKVAYGTEAGLFQRA
CCHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHC
GIPAVVCGPGDIEQAHKPDEFVALDQLVACEAFLRKVVDSLRVA
CCCEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQADTQRQSSATEANAPRGSAIEWTQRLVAYDTTSRHSNLGLIESVRDHFLAKGLRPHLS
CCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
YNPQQDKANLFVTVPAASGDTNGGIVLSGHTDVVPVDGQNWTTDPFKPVVRDGKLYGRGT
CCCCCCCCCEEEEEECCCCCCCCCEEEECCCCEEECCCCCCCCCCCHHHHHCCCEECCCC
CDMKGFIGTSLALLPTLLDAKLREPVHYALSFDEEIGCMGAPYLLAELRERGVRPAGCIV
CCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHCCCCCCCCEE
GEPTSMRVIVAHKGINAYRCCVKGHAAHSSLTPRGVNAIEYAARLICFIRDIADEFKANG
CCCCCEEEEEEECCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
PYDKAFDVPYTTAQTGTIQGGIALNTIPALCEFVFEFRNLPGVDPEALFARIQSYANDVL
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
LPKMRAEHADAGLVISKIAAAPSLDAAEQEAITQLVRALTGDRETSKVAYGTEAGLFQRA
CCHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHHC
GIPAVVCGPGDIEQAHKPDEFVALDQLVACEAFLRKVVDSLRVA
CCCEEEECCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]