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The map label for this gene is boxC [H]

Identifier: 73541019

GI number: 73541019

Start: 1420045

End: 1421727

Strand: Reverse

Name: boxC [H]

Synonym: Reut_A1325

Alternate gene names: 73541019

Gene position: 1421727-1420045 (Counterclockwise)

Preceding gene: 73541020

Following gene: 73541018

Centisome position: 37.35

GC content: 66.01

Gene sequence:

>1683_bases
ATGTCCGCGCCGGCCACCGCCCCCACTCAAGCCGCTGAACCCGTCACGTTCGAACGCCACCCCGAGCAATACCGCCACTG
GAAGCTCACATTTGACGGCCCGGTCGCCACGCTGGCGATGGATGTCGACGAAGAAGGCGGCCTGCGGCCGGGCTACACGC
TGAAGCTGAACTCCTATGACCTCGGCGTCGATATCGAACTGCACGACGCCCTGCAGCGCATCCGTTTCGAGCACCCGGAA
GTGCGCACGGTGGTGATGACCAGCGCACGCGACCGCATCTTCTGCTCGGGCGCCAATATCTTCATGCTCGGCCAGTCGAC
GCACGCGTGGAAGGTGAACTTCTGCAAGTTCACCAACGAGACGCGCAACGGCATCGAAGACGCCAGCCGCCATTCGGGCC
TCAAGTTCATCGCGGCGTGCAACGGCACCACAGCCGGCGGCGGCTATGAACTCGCCCTGGCCTGCGACGAAATCGTGCTG
GTCGACGATCGCTCTTCGGCCGTGAGCCTGCCGGAAGTGCCACTGCTCGGCGTGCTTCCCGGCACCGGCGGCCTGACCCG
CGTGACGGACAAGCGACGCGTGCGTCGCGACCATGCCGACATTTTCTGCACCACGACCGAAGGCGTGCGCGGACAGCGCG
CCAAGGACTGGAAGCTCGTCGACGACGTGGTCAAACCCGCGCGCTTTACCGAATACATTGCCGAGCGCGCGGCCGCGCTG
GCCGCCACCAGCGATCGCCCGCAGAACCACCACGGCATCGAACTGACCCCGCTGTCGCGCACCGTCGAGGAAGACGGCTA
CCGCTATGACACGGTGCGCGTCCATTTCGACCGCGCCGCGCGCAAGGCCACGATCACCGTATTCGGCCCCGACCGACACC
AGCCCACGGACCTCGCGGGCGTTGTCTCGGCGGGCGCGCAATGGTGGCCGCTCAAGATGGCGCGCGAACTGGATGACGCG
ATCCTGACGCTGCGCACGAACCATCTCGATATCGGCATGTGGATCATGAAGACTGACGGCGACGCGGCAGCCGTCCTGGC
TGCCGATGCGCTGATGGAAGCGCACGCCAGCCACTGGTTCGTGCGCGAAACGATCGGCATGCTGCGCCGTACGCTTGCGC
GGCTCGATGTGTCGTCGCGCAGCCTGTTCGCGCTGATCGAGCAGGACTCGTGCTTCGCCGGCACGCTGCTGGAACTGGCA
CTGGCGGCGGATCGCAGCTACATGCTGCATCTGCCCGACGCACCTGACGATGCGCCGCGCGTCTTCCTCAGCGAAGCCAA
CTTCGGCCGCTACCCGATGCCCAATGGGCTGTCACGGCTGGCCGCGCGCTTCTATGGGGACGAAGCCGCCATTACCGCAG
CACGTGAACACATCGGCCAGCCGCTCGATGCACTGAGCGCCGATTCACTGAGCCTGATTACCGCCGCGCCCGACGATATG
GACTGGGAAGACGAGATCCGCATCGCTGTGGAGGAGCGCGCCAGCCTGTCCCCCGATGCACTCACCGGCCTGGAAGCGAA
CCTGCGCTTCGGCCCGGGCGAAACCATGGAAACCCGGATCTTCGGACGCCTGACGGCCTGGCAGAACTGGATCTTCAACC
GCCCCAACGCGGTGGGCGAGAACGGCGCGCTCAAGGTTTTCGGGAGCGGGAACAAGCCCCGTTTCGACTGGAACCGCGTC
TGA

Upstream 100 bases:

>100_bases
GCCCTCGGCACGGCGTGCAGAAAGGTATTGCACCCTCCGTCACCATGCACTATATTTCATCGAAAGCCGCAAGGCACTAT
AGTGCATTAAGGAGACAGCC

Downstream 100 bases:

>100_bases
CGCCATAACGACCTGCAAGGAGACACGCCGTGAGCATCGACTACAGCCAGAAGATCCCGAACAACGTCAACCTGGCGGAC
GACCGCGCGCTGCAGCGCGC

Product: benzoyl-CoA-dihydrodiol lyase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 560; Mature: 559

Protein sequence:

>560_residues
MSAPATAPTQAAEPVTFERHPEQYRHWKLTFDGPVATLAMDVDEEGGLRPGYTLKLNSYDLGVDIELHDALQRIRFEHPE
VRTVVMTSARDRIFCSGANIFMLGQSTHAWKVNFCKFTNETRNGIEDASRHSGLKFIAACNGTTAGGGYELALACDEIVL
VDDRSSAVSLPEVPLLGVLPGTGGLTRVTDKRRVRRDHADIFCTTTEGVRGQRAKDWKLVDDVVKPARFTEYIAERAAAL
AATSDRPQNHHGIELTPLSRTVEEDGYRYDTVRVHFDRAARKATITVFGPDRHQPTDLAGVVSAGAQWWPLKMARELDDA
ILTLRTNHLDIGMWIMKTDGDAAAVLAADALMEAHASHWFVRETIGMLRRTLARLDVSSRSLFALIEQDSCFAGTLLELA
LAADRSYMLHLPDAPDDAPRVFLSEANFGRYPMPNGLSRLAARFYGDEAAITAAREHIGQPLDALSADSLSLITAAPDDM
DWEDEIRIAVEERASLSPDALTGLEANLRFGPGETMETRIFGRLTAWQNWIFNRPNAVGENGALKVFGSGNKPRFDWNRV

Sequences:

>Translated_560_residues
MSAPATAPTQAAEPVTFERHPEQYRHWKLTFDGPVATLAMDVDEEGGLRPGYTLKLNSYDLGVDIELHDALQRIRFEHPE
VRTVVMTSARDRIFCSGANIFMLGQSTHAWKVNFCKFTNETRNGIEDASRHSGLKFIAACNGTTAGGGYELALACDEIVL
VDDRSSAVSLPEVPLLGVLPGTGGLTRVTDKRRVRRDHADIFCTTTEGVRGQRAKDWKLVDDVVKPARFTEYIAERAAAL
AATSDRPQNHHGIELTPLSRTVEEDGYRYDTVRVHFDRAARKATITVFGPDRHQPTDLAGVVSAGAQWWPLKMARELDDA
ILTLRTNHLDIGMWIMKTDGDAAAVLAADALMEAHASHWFVRETIGMLRRTLARLDVSSRSLFALIEQDSCFAGTLLELA
LAADRSYMLHLPDAPDDAPRVFLSEANFGRYPMPNGLSRLAARFYGDEAAITAAREHIGQPLDALSADSLSLITAAPDDM
DWEDEIRIAVEERASLSPDALTGLEANLRFGPGETMETRIFGRLTAWQNWIFNRPNAVGENGALKVFGSGNKPRFDWNRV
>Mature_559_residues
SAPATAPTQAAEPVTFERHPEQYRHWKLTFDGPVATLAMDVDEEGGLRPGYTLKLNSYDLGVDIELHDALQRIRFEHPEV
RTVVMTSARDRIFCSGANIFMLGQSTHAWKVNFCKFTNETRNGIEDASRHSGLKFIAACNGTTAGGGYELALACDEIVLV
DDRSSAVSLPEVPLLGVLPGTGGLTRVTDKRRVRRDHADIFCTTTEGVRGQRAKDWKLVDDVVKPARFTEYIAERAAALA
ATSDRPQNHHGIELTPLSRTVEEDGYRYDTVRVHFDRAARKATITVFGPDRHQPTDLAGVVSAGAQWWPLKMARELDDAI
LTLRTNHLDIGMWIMKTDGDAAAVLAADALMEAHASHWFVRETIGMLRRTLARLDVSSRSLFALIEQDSCFAGTLLELAL
AADRSYMLHLPDAPDDAPRVFLSEANFGRYPMPNGLSRLAARFYGDEAAITAAREHIGQPLDALSADSLSLITAAPDDMD
WEDEIRIAVEERASLSPDALTGLEANLRFGPGETMETRIFGRLTAWQNWIFNRPNAVGENGALKVFGSGNKPRFDWNRV

Specific function: Catalyzes the ring opening of 2,3-dihydro-2,3- dihydroxybenzoyl-CoA to form 3,4-dehydroadipyl-CoA semialdehyde [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the benzoyl-CoA oxygenase component C family [H]

Homologues:

Organism=Homo sapiens, GI20127408, Length=231, Percent_Identity=29.4372294372294, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788682, Length=221, Percent_Identity=32.1266968325792, Blast_Score=79, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017633
- InterPro:   IPR001753 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.1.2.44 [H]

Molecular weight: Translated: 61913; Mature: 61782

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPATAPTQAAEPVTFERHPEQYRHWKLTFDGPVATLAMDVDEEGGLRPGYTLKLNSYD
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCEEEEECCEE
LGVDIELHDALQRIRFEHPEVRTVVMTSARDRIFCSGANIFMLGQSTHAWKVNFCKFTNE
CEEEEEHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCEEEECCCCCEEEEEEEEECCH
TRNGIEDASRHSGLKFIAACNGTTAGGGYELALACDEIVLVDDRSSAVSLPEVPLLGVLP
HHCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECEEEEEECCCCCCCCCCCCEEEEEC
GTGGLTRVTDKRRVRRDHADIFCTTTEGVRGQRAKDWKLVDDVVKPARFTEYIAERAAAL
CCCCCEECHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHH
AATSDRPQNHHGIELTPLSRTVEEDGYRYDTVRVHFDRAARKATITVFGPDRHQPTDLAG
HCCCCCCCCCCCEEEEECHHHHHHCCCEEEEEEEEEECCCCEEEEEEECCCCCCCCCHHH
VVSAGAQWWPLKMARELDDAILTLRTNHLDIGMWIMKTDGDAAAVLAADALMEAHASHWF
HHHCCCCEEHHHHHHHHCCEEEEEEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
VRETIGMLRRTLARLDVSSRSLFALIEQDSCFAGTLLELALAADRSYMLHLPDAPDDAPR
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCE
VFLSEANFGRYPMPNGLSRLAARFYGDEAAITAAREHIGQPLDALSADSLSLITAAPDDM
EEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCC
DWEDEIRIAVEERASLSPDALTGLEANLRFGPGETMETRIFGRLTAWQNWIFNRPNAVGE
CCCCCEEEEEECCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
NGALKVFGSGNKPRFDWNRV
CCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SAPATAPTQAAEPVTFERHPEQYRHWKLTFDGPVATLAMDVDEEGGLRPGYTLKLNSYD
CCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEEEECCCCCCCCCEEEEECCEE
LGVDIELHDALQRIRFEHPEVRTVVMTSARDRIFCSGANIFMLGQSTHAWKVNFCKFTNE
CEEEEEHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCEEEECCCCCEEEEEEEEECCH
TRNGIEDASRHSGLKFIAACNGTTAGGGYELALACDEIVLVDDRSSAVSLPEVPLLGVLP
HHCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEECEEEEEECCCCCCCCCCCCEEEEEC
GTGGLTRVTDKRRVRRDHADIFCTTTEGVRGQRAKDWKLVDDVVKPARFTEYIAERAAAL
CCCCCEECHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHH
AATSDRPQNHHGIELTPLSRTVEEDGYRYDTVRVHFDRAARKATITVFGPDRHQPTDLAG
HCCCCCCCCCCCEEEEECHHHHHHCCCEEEEEEEEEECCCCEEEEEEECCCCCCCCCHHH
VVSAGAQWWPLKMARELDDAILTLRTNHLDIGMWIMKTDGDAAAVLAADALMEAHASHWF
HHHCCCCEEHHHHHHHHCCEEEEEEECCEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHH
VRETIGMLRRTLARLDVSSRSLFALIEQDSCFAGTLLELALAADRSYMLHLPDAPDDAPR
HHHHHHHHHHHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCE
VFLSEANFGRYPMPNGLSRLAARFYGDEAAITAAREHIGQPLDALSADSLSLITAAPDDM
EEEECCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHCCCCHHHCCCCCEEEEEECCCCC
DWEDEIRIAVEERASLSPDALTGLEANLRFGPGETMETRIFGRLTAWQNWIFNRPNAVGE
CCCCCEEEEEECCCCCCCHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
NGALKVFGSGNKPRFDWNRV
CCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12399500 [H]