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The map label for this gene is ychM [C]

Identifier: 73540903

GI number: 73540903

Start: 1292903

End: 1294669

Strand: Reverse

Name: ychM [C]

Synonym: Reut_A1208

Alternate gene names: 73540903

Gene position: 1294669-1292903 (Counterclockwise)

Preceding gene: 73540904

Following gene: 73540902

Centisome position: 34.01

GC content: 63.78

Gene sequence:

>1767_bases
ATGGAAGACTCGTCCTCACCCGACACACAGCGCGGCGCCGCGGCCGCAGGCAGTTGGCAGACCTGGTTCCCGCCTGCGCA
GTGGCTGCTTCATTACCGGAGCGAATGGCTGCGACATGACGCCGTCGCAGGGGTCACGCTGGCGGCATATGGCATTCCGG
TTTCGTTGGCCTATGCGTCGCTGGCAGGCGTACCTCCGCAGTACGGGATCTACTGCTATCTCGCCGGCGGGCTGGCCTAC
GCGTTGTTCGGCTCGTCGCGACAGCTCGCAATCGGCCCCACGTCCGCCATCTCGATGCTGGTTGGCGTGACCATCGCCGG
AATGGCGCAGGGGGACCCGAGCCGCTGGGCATCAATCGCGGCGCTGACGGCGCTGCTGGTTGCCGCCATGTGTATCCTCG
CGTGGCTCTTTCGACTGAGTTCGCTCGTGAATTTCATCAGTGAAACGATCCTGCTGGGGTTCAAGGCGGGCGCGGCACTA
ACGATCGCCCTGACCCAGTTGCCGAAGCTGTTCGGCGTCAAGGGCGGCGGCGAGTTCTTTTTCGAGCGCATTGCCATCCT
TGCGCAGCAATTGCCGCTGACCAATCTCGCGGTGTTCGGCTTTGGCGCGGTGGCGATTGCCGTGCTGCTGCTTGGGGAAA
AGTTCCTGCCAGGACGACCGGTCGCGCTGCTCGTCGTCGTAGCGTCGATCATGCTGCTGTCGCTGACGCCGCTGGGAGCG
CTGGGCTTCAAGGTCGTAGGCGCCTTGCCACAAGGCCTGCCTGAACTGCACTGGCCGGGCCTGCGGCCCAGCGATGTCGA
CGGGGTCATTTCCCTTGCCTTTGCCTGCTTGTTGCTGTCCTACGTCGAAAGCGTCTCGGCCGCGCGCGCCCTTGCGCAGG
CCCATGGAGCCGAGATCGATGCGCGCCAGGAGCTGCTCGGACTCGGCGCGGCGAACCTGGCTACCGGCCTCTTCCAGGGC
TATCCGGTTGCGGGCGGGTTGTCGCAGTCTTCGGTGAACGACAAGGCCGGAGCGAGAACGCCGCTGGCGCTGGTGTTCGC
GTCGGCAACCATCGCCCTTTGCCTGATGTTCCTTACCGGCCTGCTGGCCAATCTGCCCAACGTGGTGCTGGCCGCCATCG
TGCTGGTCGCTGTCAAAGGCCTCGTGGATATCCGCGAACTGCGCCACTTATGGCGTGTGAGCCGCTTCGAGTTCATCGTC
TCGATGGTTGCGTTCGGCGCCGTGCTACTGCTCGGCATCCTGAAAGGTGTCATCGTCGCCGTGCTCGTATCGATGCTGAT
GATCATCCGGCGTGCTGCTCACCCGCATGTCGCGTTCCTTGGACGAATTCCGGGAACGCGCAGCTTCTCGGACATGGATC
GCAATCCGGACAATGAAGCCGTTCCGCAAATCCTGATTTTCCGTGCGGAATCGTCGCTGCTGTACTTCAACGTCGAGCAT
GTGCGCTCGGTGGTGTGGCGTGCCATTCGCAGCTCCGCGCTGCCGCTGCGGCTGGTGGTCTGCGACCTCTCGGTTTGTCC
CGTGGTCGACCTGGCAGGCGCCCGCATGCTGGCGACGCTGCACAAGGAACTGCAAGCCGCCGGCATTGAATTGCGGCTGG
TTGCAGCGCACGCGGTCGTGAGAGACATGCTTCGCGCAGAGGGACTGGAAGAGCGTGTGGGGTATTTCGGACGTCGTATC
TCGGTTGCGGATGTGATCGAGGAGTTCCGCACATCCACCGCGCAGGAGACGCCCATCGCGAGTATTACAGCGTTGGCAGC
AACGTAG

Upstream 100 bases:

>100_bases
GTGGAAAGGGATCCGTCGAGGCAAAGGCAGCATCGGCTGTGAATGACTCGTGACAGCACGAAACTTCGATGACAACAAAT
GGCGCTGATGGAGGTTCCCC

Downstream 100 bases:

>100_bases
CGCGCATTGTTGCCGCCCCGGCGCCGCGCGCGGCAGAGTATGCTGGTCCCGCATGGCGGGTGCCGGCCTTTGAGAAGGAA
AGCGTCATGAACAAACCGGA

Product: sulphate anion transporter

Products: Proton [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MEDSSSPDTQRGAAAAGSWQTWFPPAQWLLHYRSEWLRHDAVAGVTLAAYGIPVSLAYASLAGVPPQYGIYCYLAGGLAY
ALFGSSRQLAIGPTSAISMLVGVTIAGMAQGDPSRWASIAALTALLVAAMCILAWLFRLSSLVNFISETILLGFKAGAAL
TIALTQLPKLFGVKGGGEFFFERIAILAQQLPLTNLAVFGFGAVAIAVLLLGEKFLPGRPVALLVVVASIMLLSLTPLGA
LGFKVVGALPQGLPELHWPGLRPSDVDGVISLAFACLLLSYVESVSAARALAQAHGAEIDARQELLGLGAANLATGLFQG
YPVAGGLSQSSVNDKAGARTPLALVFASATIALCLMFLTGLLANLPNVVLAAIVLVAVKGLVDIRELRHLWRVSRFEFIV
SMVAFGAVLLLGILKGVIVAVLVSMLMIIRRAAHPHVAFLGRIPGTRSFSDMDRNPDNEAVPQILIFRAESSLLYFNVEH
VRSVVWRAIRSSALPLRLVVCDLSVCPVVDLAGARMLATLHKELQAAGIELRLVAAHAVVRDMLRAEGLEERVGYFGRRI
SVADVIEEFRTSTAQETPIASITALAAT

Sequences:

>Translated_588_residues
MEDSSSPDTQRGAAAAGSWQTWFPPAQWLLHYRSEWLRHDAVAGVTLAAYGIPVSLAYASLAGVPPQYGIYCYLAGGLAY
ALFGSSRQLAIGPTSAISMLVGVTIAGMAQGDPSRWASIAALTALLVAAMCILAWLFRLSSLVNFISETILLGFKAGAAL
TIALTQLPKLFGVKGGGEFFFERIAILAQQLPLTNLAVFGFGAVAIAVLLLGEKFLPGRPVALLVVVASIMLLSLTPLGA
LGFKVVGALPQGLPELHWPGLRPSDVDGVISLAFACLLLSYVESVSAARALAQAHGAEIDARQELLGLGAANLATGLFQG
YPVAGGLSQSSVNDKAGARTPLALVFASATIALCLMFLTGLLANLPNVVLAAIVLVAVKGLVDIRELRHLWRVSRFEFIV
SMVAFGAVLLLGILKGVIVAVLVSMLMIIRRAAHPHVAFLGRIPGTRSFSDMDRNPDNEAVPQILIFRAESSLLYFNVEH
VRSVVWRAIRSSALPLRLVVCDLSVCPVVDLAGARMLATLHKELQAAGIELRLVAAHAVVRDMLRAEGLEERVGYFGRRI
SVADVIEEFRTSTAQETPIASITALAAT
>Mature_588_residues
MEDSSSPDTQRGAAAAGSWQTWFPPAQWLLHYRSEWLRHDAVAGVTLAAYGIPVSLAYASLAGVPPQYGIYCYLAGGLAY
ALFGSSRQLAIGPTSAISMLVGVTIAGMAQGDPSRWASIAALTALLVAAMCILAWLFRLSSLVNFISETILLGFKAGAAL
TIALTQLPKLFGVKGGGEFFFERIAILAQQLPLTNLAVFGFGAVAIAVLLLGEKFLPGRPVALLVVVASIMLLSLTPLGA
LGFKVVGALPQGLPELHWPGLRPSDVDGVISLAFACLLLSYVESVSAARALAQAHGAEIDARQELLGLGAANLATGLFQG
YPVAGGLSQSSVNDKAGARTPLALVFASATIALCLMFLTGLLANLPNVVLAAIVLVAVKGLVDIRELRHLWRVSRFEFIV
SMVAFGAVLLLGILKGVIVAVLVSMLMIIRRAAHPHVAFLGRIPGTRSFSDMDRNPDNEAVPQILIFRAESSLLYFNVEH
VRSVVWRAIRSSALPLRLVVCDLSVCPVVDLAGARMLATLHKELQAAGIELRLVAAHAVVRDMLRAEGLEERVGYFGRRI
SVADVIEEFRTSTAQETPIASITALAAT

Specific function: Expression in E.coli induces sulfate uptake during early-to mid-log phase growth. Uptake is maximal at pH 6.0, is sulfate-specific, requires E.coli CysA and the transmembrane segment but not the STAS domain of the protein [H]

COG id: COG0659

COG function: function code P; Sulfate permease and related transporters (MFS superfamily)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

Organism=Homo sapiens, GI45827800, Length=504, Percent_Identity=29.3650793650794, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI39752683, Length=504, Percent_Identity=29.3650793650794, Blast_Score=192, Evalue=1e-48,
Organism=Homo sapiens, GI262206105, Length=564, Percent_Identity=27.6595744680851, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI262206075, Length=564, Percent_Identity=27.6595744680851, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI262206069, Length=564, Percent_Identity=27.6595744680851, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI262206063, Length=564, Percent_Identity=27.6595744680851, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI94721255, Length=517, Percent_Identity=27.852998065764, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI94721259, Length=517, Percent_Identity=27.852998065764, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI94721253, Length=517, Percent_Identity=27.852998065764, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI94721257, Length=506, Percent_Identity=27.8656126482213, Blast_Score=173, Evalue=5e-43,
Organism=Homo sapiens, GI45827802, Length=459, Percent_Identity=29.6296296296296, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI269784651, Length=503, Percent_Identity=27.037773359841, Blast_Score=155, Evalue=1e-37,
Organism=Homo sapiens, GI4557535, Length=523, Percent_Identity=25.6214149139579, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI4505697, Length=513, Percent_Identity=26.7056530214425, Blast_Score=148, Evalue=2e-35,
Organism=Homo sapiens, GI100913030, Length=608, Percent_Identity=24.8355263157895, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI47131207, Length=637, Percent_Identity=25.5886970172684, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI20336272, Length=637, Percent_Identity=25.5886970172684, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI16418457, Length=516, Percent_Identity=23.062015503876, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI301601599, Length=516, Percent_Identity=23.062015503876, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI16306483, Length=514, Percent_Identity=24.124513618677, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI20336282, Length=514, Percent_Identity=24.124513618677, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI16418413, Length=501, Percent_Identity=25.1497005988024, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI217272867, Length=501, Percent_Identity=25.1497005988024, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI65506789, Length=391, Percent_Identity=27.1099744245524, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI301601602, Length=210, Percent_Identity=24.2857142857143, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI45827804, Length=216, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI87081859, Length=571, Percent_Identity=25.569176882662, Blast_Score=109, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI86565215, Length=571, Percent_Identity=28.3712784588441, Blast_Score=217, Evalue=1e-56,
Organism=Caenorhabditis elegans, GI17566848, Length=557, Percent_Identity=28.1867145421903, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI86564196, Length=603, Percent_Identity=23.8805970149254, Blast_Score=182, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17562578, Length=615, Percent_Identity=24.5528455284553, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17551690, Length=514, Percent_Identity=25.2918287937743, Blast_Score=158, Evalue=8e-39,
Organism=Caenorhabditis elegans, GI86564876, Length=646, Percent_Identity=21.2074303405573, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193203292, Length=502, Percent_Identity=25.0996015936255, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI86565213, Length=268, Percent_Identity=30.9701492537313, Blast_Score=108, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI86565211, Length=241, Percent_Identity=31.1203319502075, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI86565209, Length=241, Percent_Identity=31.1203319502075, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6319771, Length=477, Percent_Identity=25.9958071278826, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323121, Length=482, Percent_Identity=26.3485477178423, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6325260, Length=581, Percent_Identity=23.7521514629948, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24651449, Length=597, Percent_Identity=27.9731993299832, Blast_Score=193, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24649801, Length=563, Percent_Identity=26.6429840142096, Blast_Score=178, Evalue=8e-45,
Organism=Drosophila melanogaster, GI85815873, Length=460, Percent_Identity=27.1739130434783, Blast_Score=167, Evalue=1e-41,
Organism=Drosophila melanogaster, GI21358229, Length=550, Percent_Identity=26.5454545454545, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI19922482, Length=536, Percent_Identity=25.5597014925373, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24663084, Length=572, Percent_Identity=27.6223776223776, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21357695, Length=572, Percent_Identity=27.6223776223776, Blast_Score=151, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666186, Length=494, Percent_Identity=25.3036437246964, Blast_Score=142, Evalue=5e-34,
Organism=Drosophila melanogaster, GI24647160, Length=557, Percent_Identity=26.3913824057451, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI21355087, Length=553, Percent_Identity=25.1356238698011, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI21358633, Length=473, Percent_Identity=25.369978858351, Blast_Score=132, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645
- InterPro:   IPR001902
- InterPro:   IPR011547 [H]

Pfam domain/function: PF01740 STAS; PF00916 Sulfate_transp [H]

EC number: NA

Molecular weight: Translated: 62298; Mature: 62298

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDSSSPDTQRGAAAAGSWQTWFPPAQWLLHYRSEWLRHDAVAGVTLAAYGIPVSLAYAS
CCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LAGVPPQYGIYCYLAGGLAYALFGSSRQLAIGPTSAISMLVGVTIAGMAQGDPSRWASIA
HCCCCCCCCEEEEEHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALTALLVAAMCILAWLFRLSSLVNFISETILLGFKAGAALTIALTQLPKLFGVKGGGEFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHH
FERIAILAQQLPLTNLAVFGFGAVAIAVLLLGEKFLPGRPVALLVVVASIMLLSLTPLGA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
LGFKVVGALPQGLPELHWPGLRPSDVDGVISLAFACLLLSYVESVSAARALAQAHGAEID
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ARQELLGLGAANLATGLFQGYPVAGGLSQSSVNDKAGARTPLALVFASATIALCLMFLTG
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLANLPNVVLAAIVLVAVKGLVDIRELRHLWRVSRFEFIVSMVAFGAVLLLGILKGVIVA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVSMLMIIRRAAHPHVAFLGRIPGTRSFSDMDRNPDNEAVPQILIFRAESSLLYFNVEH
HHHHHHHHHHHHCCCCEEEEECCCCCCCCHHCCCCCCCHHHHHEEEEEECCCEEEEEHHH
VRSVVWRAIRSSALPLRLVVCDLSVCPVVDLAGARMLATLHKELQAAGIELRLVAAHAVV
HHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
RDMLRAEGLEERVGYFGRRISVADVIEEFRTSTAQETPIASITALAAT
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCC
>Mature Secondary Structure
MEDSSSPDTQRGAAAAGSWQTWFPPAQWLLHYRSEWLRHDAVAGVTLAAYGIPVSLAYAS
CCCCCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
LAGVPPQYGIYCYLAGGLAYALFGSSRQLAIGPTSAISMLVGVTIAGMAQGDPSRWASIA
HCCCCCCCCEEEEEHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHCCCCCHHHHHHHH
ALTALLVAAMCILAWLFRLSSLVNFISETILLGFKAGAALTIALTQLPKLFGVKGGGEFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHH
FERIAILAQQLPLTNLAVFGFGAVAIAVLLLGEKFLPGRPVALLVVVASIMLLSLTPLGA
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHH
LGFKVVGALPQGLPELHWPGLRPSDVDGVISLAFACLLLSYVESVSAARALAQAHGAEID
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ARQELLGLGAANLATGLFQGYPVAGGLSQSSVNDKAGARTPLALVFASATIALCLMFLTG
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LLANLPNVVLAAIVLVAVKGLVDIRELRHLWRVSRFEFIVSMVAFGAVLLLGILKGVIVA
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLVSMLMIIRRAAHPHVAFLGRIPGTRSFSDMDRNPDNEAVPQILIFRAESSLLYFNVEH
HHHHHHHHHHHHCCCCEEEEECCCCCCCCHHCCCCCCCHHHHHEEEEEECCCEEEEEHHH
VRSVVWRAIRSSALPLRLVVCDLSVCPVVDLAGARMLATLHKELQAAGIELRLVAAHAVV
HHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHH
RDMLRAEGLEERVGYFGRRISVADVIEEFRTSTAQETPIASITALAAT
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; SO42- [Periplasm] [C]

Specific reaction: Proton [Periplasm] + SO42- [Periplasm] = Proton [Cytoplasm] + SO42- [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]