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The map label for this gene is ycgM [C]

Identifier: 73540837

GI number: 73540837

Start: 1228820

End: 1229689

Strand: Direct

Name: ycgM [C]

Synonym: Reut_A1135

Alternate gene names: 73540837

Gene position: 1228820-1229689 (Clockwise)

Preceding gene: 73540836

Following gene: 73540842

Centisome position: 32.28

GC content: 61.49

Gene sequence:

>870_bases
ATGAAGCTCGCCACATTCCAATTCCGCGGATATCAATCCATTGGTAAGATCGAAGGTCAACAGATCATCGATCTGCCCGC
GAGCGATTGCAGTCTGCCTCGTACCATGCTGGAGTTCCTCCAAGGCGGCCGCGCGCCCATGCAGCGCGCGCGCGACCTGC
GTATCGCTGACGCCGTCACCTACCCGCTCGCAGATGTGCGACTCGACGCTCCCGTGCCGAACCCGTCAAAGTTTCTTGCG
ATCGGCATGAACTATCGCCGTCATGTCGAAGAAGCCGTCGCTGCCGGCATCCAGGTGCCAGACAGCCAGGTCTGGTTCAG
CAAGCAGGTGTCGTGCGTAAATGGGCCGTTCGACCCGGTGCAGATGCCGAAAGTGTCCGACAAGCTCGATTACGAAGCGG
AGCTTGGTGTCGTTATCGGCCGCCGCTGCCGTCACGTGTCGGAGGAGGACGCGGCGTCAGTCGTCGCGGGCTATGTCATC
TGCAACGACGTTTCAGTGCGCGACTGGCAGATGCGCTCACCGACCATCATGCTCGGCAAGTCGTTCAACACGCATGGCCC
CTTCGGCCCGTGGCTTGTCACGCCTGACGAAATCGCCGATCCGCATGCGCTGCGGCTGCGCATGATCGTGAACGGCGAAT
GCCGCCAGGAGGTCAACACTGGGGAGATGATCTACAACATCTGGCAACAGATCGCTTATCTGTCGACAGTGATGACACTC
GAAGCCGGCGATGTCCTCGCGACGGGCACACCGTCAGGCGTCGGCGTTGCCCACAAGCCGTCGCGTTTCCTGCGCGTCGG
CGACGTGATGCGCGTCGAGATCGACGGCGTGGGTCACATCGAGAACGTCGTTGTCGCTGAGCCGGTCTGA

Upstream 100 bases:

>100_bases
GTGGAGCGAGTACCTGACGCGTCAACGAAGGATCGTTAGGGCATGCGCGTTAGCGCACGCGATCCCTTGCCATCCTTTGC
CTTTTTTCAGATGAACCACT

Downstream 100 bases:

>100_bases
CTGAGGGAGCCAACCGTGGCACGAAAAGTACACTCCGACCTCAATCCTGTTGAAGTGCCTGCCTTATCCGAGTTCATGAC
GGACGACATCTTGACTCCTG

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKLATFQFRGYQSIGKIEGQQIIDLPASDCSLPRTMLEFLQGGRAPMQRARDLRIADAVTYPLADVRLDAPVPNPSKFLA
IGMNYRRHVEEAVAAGIQVPDSQVWFSKQVSCVNGPFDPVQMPKVSDKLDYEAELGVVIGRRCRHVSEEDAASVVAGYVI
CNDVSVRDWQMRSPTIMLGKSFNTHGPFGPWLVTPDEIADPHALRLRMIVNGECRQEVNTGEMIYNIWQQIAYLSTVMTL
EAGDVLATGTPSGVGVAHKPSRFLRVGDVMRVEIDGVGHIENVVVAEPV

Sequences:

>Translated_289_residues
MKLATFQFRGYQSIGKIEGQQIIDLPASDCSLPRTMLEFLQGGRAPMQRARDLRIADAVTYPLADVRLDAPVPNPSKFLA
IGMNYRRHVEEAVAAGIQVPDSQVWFSKQVSCVNGPFDPVQMPKVSDKLDYEAELGVVIGRRCRHVSEEDAASVVAGYVI
CNDVSVRDWQMRSPTIMLGKSFNTHGPFGPWLVTPDEIADPHALRLRMIVNGECRQEVNTGEMIYNIWQQIAYLSTVMTL
EAGDVLATGTPSGVGVAHKPSRFLRVGDVMRVEIDGVGHIENVVVAEPV
>Mature_289_residues
MKLATFQFRGYQSIGKIEGQQIIDLPASDCSLPRTMLEFLQGGRAPMQRARDLRIADAVTYPLADVRLDAPVPNPSKFLA
IGMNYRRHVEEAVAAGIQVPDSQVWFSKQVSCVNGPFDPVQMPKVSDKLDYEAELGVVIGRRCRHVSEEDAASVVAGYVI
CNDVSVRDWQMRSPTIMLGKSFNTHGPFGPWLVTPDEIADPHALRLRMIVNGECRQEVNTGEMIYNIWQQIAYLSTVMTL
EAGDVLATGTPSGVGVAHKPSRFLRVGDVMRVEIDGVGHIENVVVAEPV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=287, Percent_Identity=42.1602787456446, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI40786394, Length=287, Percent_Identity=41.4634146341463, Blast_Score=211, Evalue=5e-55,
Organism=Homo sapiens, GI66348062, Length=182, Percent_Identity=40.6593406593407, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI215422413, Length=182, Percent_Identity=40.6593406593407, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI13654274, Length=182, Percent_Identity=40.6593406593407, Blast_Score=126, Evalue=2e-29,
Organism=Escherichia coli, GI1787428, Length=213, Percent_Identity=34.7417840375587, Blast_Score=115, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17557057, Length=183, Percent_Identity=33.879781420765, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324161, Length=245, Percent_Identity=23.6734693877551, Blast_Score=66, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28572127, Length=224, Percent_Identity=38.8392857142857, Blast_Score=153, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24663695, Length=274, Percent_Identity=32.8467153284672, Blast_Score=146, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28571789, Length=218, Percent_Identity=33.0275229357798, Blast_Score=114, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 31861; Mature: 31861

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLATFQFRGYQSIGKIEGQQIIDLPASDCSLPRTMLEFLQGGRAPMQRARDLRIADAVT
CCEEEEEECCCHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHH
YPLADVRLDAPVPNPSKFLAIGMNYRRHVEEAVAAGIQVPDSQVWFSKQVSCVNGPFDPV
CCHHHEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCHHHHCCEECCCCCCCC
QMPKVSDKLDYEAELGVVIGRRCRHVSEEDAASVVAGYVICNDVSVRDWQMRSPTIMLGK
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCEECCCCEEEEEC
SFNTHGPFGPWLVTPDEIADPHALRLRMIVNGECRQEVNTGEMIYNIWQQIAYLSTVMTL
CCCCCCCCCCEEECHHHHCCCCCEEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHEE
EAGDVLATGTPSGVGVAHKPSRFLRVGDVMRVEIDGVGHIENVVVAEPV
ECCCEEECCCCCCCCCCCCCHHHEEECCEEEEEECCCCCCCCEEEECCC
>Mature Secondary Structure
MKLATFQFRGYQSIGKIEGQQIIDLPASDCSLPRTMLEFLQGGRAPMQRARDLRIADAVT
CCEEEEEECCCHHHHCCCCCEEEECCCCCCCCHHHHHHHHCCCCCHHHHHHCCCHHHHHH
YPLADVRLDAPVPNPSKFLAIGMNYRRHVEEAVAAGIQVPDSQVWFSKQVSCVNGPFDPV
CCHHHEEECCCCCCCCCEEEECCHHHHHHHHHHHCCCCCCCCCCHHHHCCEECCCCCCCC
QMPKVSDKLDYEAELGVVIGRRCRHVSEEDAASVVAGYVICNDVSVRDWQMRSPTIMLGK
CCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCCEECCCCEEEEEC
SFNTHGPFGPWLVTPDEIADPHALRLRMIVNGECRQEVNTGEMIYNIWQQIAYLSTVMTL
CCCCCCCCCCEEECHHHHCCCCCEEEEEEECCHHHHCCCCHHHHHHHHHHHHHHHHHHEE
EAGDVLATGTPSGVGVAHKPSRFLRVGDVMRVEIDGVGHIENVVVAEPV
ECCCEEECCCCCCCCCCCCCHHHEEECCEEEEEECCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA