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The map label for this gene is yfjP [H]

Identifier: 73540825

GI number: 73540825

Start: 1215358

End: 1216128

Strand: Direct

Name: yfjP [H]

Synonym: Reut_A1123

Alternate gene names: 73540825

Gene position: 1215358-1216128 (Clockwise)

Preceding gene: 73540824

Following gene: 73540826

Centisome position: 31.93

GC content: 65.63

Gene sequence:

>771_bases
ATGGAGGCGTGCTTGAACGCTGCCGCGCGCAAGCCCGCCGCACCGGCCAAGACCACCAGCTCCCGTGCCGCCAAAGGCAG
CGCCAAGGAAGGGAAGGTCGCGCTGCCGGAAGCCGAGGTTTTGCCGTTGCCGGTCGAGACCGTCATCGACGCCGTACGCC
CGGCCTATTGGGACGAGGCCTGTGCCGACCTGATGAAGCGCGACCGCATCCTGCGCAAGATGATCCCGACCTATGGTCCG
GCCCATCTGGTCTCTCGCGGCGATCCGTTCATCACCCTCGCTCGCTCGGTCGTGGGCCAGCAGATCTCCGTCAAGGCGGC
GCAGTCGGTCTGGGAGCGGCTGGTGGGGGCATGCCCCAAGCTCACGCCGGCACAGTTCCTGCGGGCGGGTCCCGAGAAGC
TGGCTGCGTGCGGGCTCTCGCGGCGCAAGGCGGAATACATTACCGACCTGGCTGATCACTTCAAGGCCGGCCGCGTCCAC
GTGAACGAATGGGCGGTGATGGACGATGAAGCCGTCATCGCCGAGCTGACGCAGATCCGCGGCATCGGCCGATGGACGGC
TGAAATGTTCCTGATGTTCAACCTGATGCGGCCTAACGTGCTGCCTCTGGACGACATCGGGCTGATCAACGCCATCTCGG
CAAATTACTTCAGCGGCGAGCCCGTGACCCGTAGCGAAGCGCGAGAAGTCGCGGCAAACTGGGAGCCCTGGCGCACGGTG
GCCACATGGTACATGTGGCGTAGCCTGGACCCGCTGCCGGTGACGTATTAG

Upstream 100 bases:

>100_bases
CTGCCAAGGCCGAACGCAACTTCGCTGAAGCCGACCGCATCCGCGCGGATCTTCTGGCCGCAGGCATCGTGCTGGAAGAC
AAGCCGGGCGGTGCGACCGA

Downstream 100 bases:

>100_bases
GCATAGCCGTAAGAAAAAGTAGCTGCAGGTGCAGTAAAGGCTATCTGCCCGGCGCAAAGATAGCGGCCAAATTCCGGTAG
AATGCGCCCCTTCACAGACA

Product: HhH-GPD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MEACLNAAARKPAAPAKTTSSRAAKGSAKEGKVALPEAEVLPLPVETVIDAVRPAYWDEACADLMKRDRILRKMIPTYGP
AHLVSRGDPFITLARSVVGQQISVKAAQSVWERLVGACPKLTPAQFLRAGPEKLAACGLSRRKAEYITDLADHFKAGRVH
VNEWAVMDDEAVIAELTQIRGIGRWTAEMFLMFNLMRPNVLPLDDIGLINAISANYFSGEPVTRSEAREVAANWEPWRTV
ATWYMWRSLDPLPVTY

Sequences:

>Translated_256_residues
MEACLNAAARKPAAPAKTTSSRAAKGSAKEGKVALPEAEVLPLPVETVIDAVRPAYWDEACADLMKRDRILRKMIPTYGP
AHLVSRGDPFITLARSVVGQQISVKAAQSVWERLVGACPKLTPAQFLRAGPEKLAACGLSRRKAEYITDLADHFKAGRVH
VNEWAVMDDEAVIAELTQIRGIGRWTAEMFLMFNLMRPNVLPLDDIGLINAISANYFSGEPVTRSEAREVAANWEPWRTV
ATWYMWRSLDPLPVTY
>Mature_256_residues
MEACLNAAARKPAAPAKTTSSRAAKGSAKEGKVALPEAEVLPLPVETVIDAVRPAYWDEACADLMKRDRILRKMIPTYGP
AHLVSRGDPFITLARSVVGQQISVKAAQSVWERLVGACPKLTPAQFLRAGPEKLAACGLSRRKAEYITDLADHFKAGRVH
VNEWAVMDDEAVIAELTQIRGIGRWTAEMFLMFNLMRPNVLPLDDIGLINAISANYFSGEPVTRSEAREVAANWEPWRTV
ATWYMWRSLDPLPVTY

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, 3-methylguanine, 7-methylguanine, O2- methylthymine, and O2-methylcytosine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkylbase DNA glycosidase alkA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6320990, Length=197, Percent_Identity=32.48730964467, Blast_Score=78, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR023170 [H]

Pfam domain/function: PF00730 HhH-GPD [H]

EC number: =3.2.2.21 [H]

Molecular weight: Translated: 28301; Mature: 28301

Theoretical pI: Translated: 8.61; Mature: 8.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEACLNAAARKPAAPAKTTSSRAAKGSAKEGKVALPEAEVLPLPVETVIDAVRPAYWDEA
CCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHCHHHHHHH
CADLMKRDRILRKMIPTYGPAHLVSRGDPFITLARSVVGQQISVKAAQSVWERLVGACPK
HHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
LTPAQFLRAGPEKLAACGLSRRKAEYITDLADHFKAGRVHVNEWAVMDDEAVIAELTQIR
CCHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCEEEECCHHHHHHHHHHH
GIGRWTAEMFLMFNLMRPNVLPLDDIGLINAISANYFSGEPVTRSEAREVAANWEPWRTV
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHH
ATWYMWRSLDPLPVTY
HHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEACLNAAARKPAAPAKTTSSRAAKGSAKEGKVALPEAEVLPLPVETVIDAVRPAYWDEA
CCHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHCHHHHHHH
CADLMKRDRILRKMIPTYGPAHLVSRGDPFITLARSVVGQQISVKAAQSVWERLVGACPK
HHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCC
LTPAQFLRAGPEKLAACGLSRRKAEYITDLADHFKAGRVHVNEWAVMDDEAVIAELTQIR
CCHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCEEECCEEEECCHHHHHHHHHHH
GIGRWTAEMFLMFNLMRPNVLPLDDIGLINAISANYFSGEPVTRSEAREVAANWEPWRTV
CCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCCHHHHH
ATWYMWRSLDPLPVTY
HHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]