Click here to switch to the map view.

The map label for this gene is cysS [H]

Identifier: 73540824

GI number: 73540824

Start: 1213985

End: 1215373

Strand: Direct

Name: cysS [H]

Synonym: Reut_A1122

Alternate gene names: 73540824

Gene position: 1213985-1215373 (Clockwise)

Preceding gene: 73540819

Following gene: 73540825

Centisome position: 31.89

GC content: 62.35

Gene sequence:

>1389_bases
ATGCAGCTTCTGAACATCTACAACACGCTCGCGCGTGAGAAACAGCCTTTCGTGCCGATCGAGCCGGGCAAAGTCCGCAT
GTACGTATGCGGCATGACCGTCTACGACTACTGTCACGTTGGCCACGCGCGCGTGATGGTGGTGTTCGACATGGTGCATC
GCTGGCTGCGCGCCGCGGGCTATGACGTGACCTTTGTCCAGAACATCACGGACATCGACGACAAGATCATCCGCCGCGCC
GCCGAAAACGGCGAAACCATTGGCCAGCTGACTACCCGCTTCATCCAGTACATGCACGAGGATGCCGACGCGTTGGGGAT
CGTCCGACCGGACCATGAGCCGCGCGCGACCGACTATGTGCCGCAGATGCTGGACCTGATTGGCAAGCTCGAAGCCAATG
GCCTGGCCTATCAGGCTACGGACGGCGACGTGAACTACTCGGTGCGCAAGTTCGATGGCTACGGCAAGCTCTCCGGCAAG
TCGCTGGAAGATCTGCGCGCCGGCGAGCGTGTGACCGCCAACGATGCCAAGCAGGACCCGCTCGATTTCGTGCTGTGGAA
GTCGGCCAAGGAAAGCGAGCCGCCCGAGAGCAAGTGGAATTCGAAGTGGGGCATGGGCCGCCCGGGCTGGCACATCGAAT
GCTCGGCCATGAGCTGCACGCTGCTGGGCGAGCATTTCGACATCCACGGCGGTGGTGCCGACCTGCAGTTCCCGCACCAC
GAGAACGAAATTGCCCAGTCTGAAGGTGCGAGCGGCAAGCCGTTCGTCAATGTGTGGATGCACAACGGTTTCGTGCGCGT
GAATGACGAGAAGATGTCGAAATCGCTCGGCAACTTCTTCACCATCCGCGAAGTGCTGAAGGAGTACGACGCGGAAGTCG
TGCGCTTCTTCATCCTGCGCGCGCACTACCGCAGCCCGCTGAACTACAGCGATGCCCACCTCGACGACGCGCGCCATGCG
CTGACGCGGCTCTACACGGCGCTCAAGGACACGCAGCCCGGCGGCTATGCCGTGGACTGGGAAGAGGCGCACGCAAAGCG
CTTTGCCGAAGCCATGTGCGATGACTTCAACACGCCGATTGCGGTGTCCGTGCTGTTCGATCTGGCCAGCGAAGTCAACC
GTACGGGCTCTTCGGTGGCCGCACGCCAACTGAAGGGACTGGCTGGCACGCTGGGCCTGCTCGAACGCGATCCGCACACG
TTCCTGCAAGGTGGCAAAAAGGTCGACGGCCCGTCGCCGGATGAGATCGAAGGTTTGATCGCCGCGCGCAAGACTGCCAA
GGCCGAACGCAACTTCGCTGAAGCCGACCGCATCCGCGCGGATCTTCTGGCCGCAGGCATCGTGCTGGAAGACAAGCCGG
GCGGTGCGACCGAATGGAGGCGTGCTTGA

Upstream 100 bases:

>100_bases
CCGGTGTTTGCGCGCGTGCGCCGCCGCTTGGGGCCCCACGAAGGATACAGGGCCGGGCGACGGCATACCGGCAGCCACCT
CACATCACACACATTGCTTC

Downstream 100 bases:

>100_bases
ACGCTGCCGCGCGCAAGCCCGCCGCACCGGCCAAGACCACCAGCTCCCGTGCCGCCAAAGGCAGCGCCAAGGAAGGGAAG
GTCGCGCTGCCGGAAGCCGA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 462; Mature: 462

Protein sequence:

>462_residues
MQLLNIYNTLAREKQPFVPIEPGKVRMYVCGMTVYDYCHVGHARVMVVFDMVHRWLRAAGYDVTFVQNITDIDDKIIRRA
AENGETIGQLTTRFIQYMHEDADALGIVRPDHEPRATDYVPQMLDLIGKLEANGLAYQATDGDVNYSVRKFDGYGKLSGK
SLEDLRAGERVTANDAKQDPLDFVLWKSAKESEPPESKWNSKWGMGRPGWHIECSAMSCTLLGEHFDIHGGGADLQFPHH
ENEIAQSEGASGKPFVNVWMHNGFVRVNDEKMSKSLGNFFTIREVLKEYDAEVVRFFILRAHYRSPLNYSDAHLDDARHA
LTRLYTALKDTQPGGYAVDWEEAHAKRFAEAMCDDFNTPIAVSVLFDLASEVNRTGSSVAARQLKGLAGTLGLLERDPHT
FLQGGKKVDGPSPDEIEGLIAARKTAKAERNFAEADRIRADLLAAGIVLEDKPGGATEWRRA

Sequences:

>Translated_462_residues
MQLLNIYNTLAREKQPFVPIEPGKVRMYVCGMTVYDYCHVGHARVMVVFDMVHRWLRAAGYDVTFVQNITDIDDKIIRRA
AENGETIGQLTTRFIQYMHEDADALGIVRPDHEPRATDYVPQMLDLIGKLEANGLAYQATDGDVNYSVRKFDGYGKLSGK
SLEDLRAGERVTANDAKQDPLDFVLWKSAKESEPPESKWNSKWGMGRPGWHIECSAMSCTLLGEHFDIHGGGADLQFPHH
ENEIAQSEGASGKPFVNVWMHNGFVRVNDEKMSKSLGNFFTIREVLKEYDAEVVRFFILRAHYRSPLNYSDAHLDDARHA
LTRLYTALKDTQPGGYAVDWEEAHAKRFAEAMCDDFNTPIAVSVLFDLASEVNRTGSSVAARQLKGLAGTLGLLERDPHT
FLQGGKKVDGPSPDEIEGLIAARKTAKAERNFAEADRIRADLLAAGIVLEDKPGGATEWRRA
>Mature_462_residues
MQLLNIYNTLAREKQPFVPIEPGKVRMYVCGMTVYDYCHVGHARVMVVFDMVHRWLRAAGYDVTFVQNITDIDDKIIRRA
AENGETIGQLTTRFIQYMHEDADALGIVRPDHEPRATDYVPQMLDLIGKLEANGLAYQATDGDVNYSVRKFDGYGKLSGK
SLEDLRAGERVTANDAKQDPLDFVLWKSAKESEPPESKWNSKWGMGRPGWHIECSAMSCTLLGEHFDIHGGGADLQFPHH
ENEIAQSEGASGKPFVNVWMHNGFVRVNDEKMSKSLGNFFTIREVLKEYDAEVVRFFILRAHYRSPLNYSDAHLDDARHA
LTRLYTALKDTQPGGYAVDWEEAHAKRFAEAMCDDFNTPIAVSVLFDLASEVNRTGSSVAARQLKGLAGTLGLLERDPHT
FLQGGKKVDGPSPDEIEGLIAARKTAKAERNFAEADRIRADLLAAGIVLEDKPGGATEWRRA

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=387, Percent_Identity=38.7596899224806, Blast_Score=245, Evalue=6e-65,
Organism=Homo sapiens, GI303304987, Length=308, Percent_Identity=36.3636363636364, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI21269877, Length=308, Percent_Identity=36.3636363636364, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI10835051, Length=308, Percent_Identity=36.3636363636364, Blast_Score=178, Evalue=1e-44,
Organism=Homo sapiens, GI62240992, Length=308, Percent_Identity=36.3636363636364, Blast_Score=178, Evalue=1e-44,
Organism=Escherichia coli, GI1786737, Length=469, Percent_Identity=55.2238805970149, Blast_Score=494, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17509797, Length=364, Percent_Identity=32.1428571428571, Blast_Score=179, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI17509795, Length=364, Percent_Identity=32.1428571428571, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6324082, Length=339, Percent_Identity=31.858407079646, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI19922218, Length=391, Percent_Identity=35.8056265984655, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI19922364, Length=310, Percent_Identity=37.0967741935484, Blast_Score=179, Evalue=3e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 51690; Mature: 51690

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLLNIYNTLAREKQPFVPIEPGKVRMYVCGMTVYDYCHVGHARVMVVFDMVHRWLRAAG
CCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHCC
YDVTFVQNITDIDDKIIRRAAENGETIGQLTTRFIQYMHEDADALGIVRPDHEPRATDYV
CCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHH
PQMLDLIGKLEANGLAYQATDGDVNYSVRKFDGYGKLSGKSLEDLRAGERVTANDAKQDP
HHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCC
LDFVLWKSAKESEPPESKWNSKWGMGRPGWHIECSAMSCTLLGEHFDIHGGGADLQFPHH
CCEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEECCEEEEEECCCEEECCCCCCCCCCCC
ENEIAQSEGASGKPFVNVWMHNGFVRVNDEKMSKSLGNFFTIREVLKEYDAEVVRFFILR
CCHHHHCCCCCCCCEEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHYRSPLNYSDAHLDDARHALTRLYTALKDTQPGGYAVDWEEAHAKRFAEAMCDDFNTPI
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHCCCCCH
AVSVLFDLASEVNRTGSSVAARQLKGLAGTLGLLERDPHTFLQGGKKVDGPSPDEIEGLI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHH
AARKTAKAERNFAEADRIRADLLAAGIVLEDKPGGATEWRRA
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MQLLNIYNTLAREKQPFVPIEPGKVRMYVCGMTVYDYCHVGHARVMVVFDMVHRWLRAAG
CCHHHHHHHHHHCCCCCCCCCCCCEEEEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHCC
YDVTFVQNITDIDDKIIRRAAENGETIGQLTTRFIQYMHEDADALGIVRPDHEPRATDYV
CCEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHH
PQMLDLIGKLEANGLAYQATDGDVNYSVRKFDGYGKLSGKSLEDLRAGERVTANDAKQDP
HHHHHHHHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHCCCCCCCCCCCCCC
LDFVLWKSAKESEPPESKWNSKWGMGRPGWHIECSAMSCTLLGEHFDIHGGGADLQFPHH
CCEEEECCCCCCCCCCHHCCCCCCCCCCCCEEEECCEEEEEECCCEEECCCCCCCCCCCC
ENEIAQSEGASGKPFVNVWMHNGFVRVNDEKMSKSLGNFFTIREVLKEYDAEVVRFFILR
CCHHHHCCCCCCCCEEEEEEECCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHYRSPLNYSDAHLDDARHALTRLYTALKDTQPGGYAVDWEEAHAKRFAEAMCDDFNTPI
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHHCCCCCH
AVSVLFDLASEVNRTGSSVAARQLKGLAGTLGLLERDPHTFLQGGKKVDGPSPDEIEGLI
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCHHHHHHHH
AARKTAKAERNFAEADRIRADLLAAGIVLEDKPGGATEWRRA
HHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA