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The map label for this gene is kdsA [H]

Identifier: 73540791

GI number: 73540791

Start: 1183504

End: 1184373

Strand: Direct

Name: kdsA [H]

Synonym: Reut_A1089

Alternate gene names: 73540791

Gene position: 1183504-1184373 (Clockwise)

Preceding gene: 73540790

Following gene: 73540792

Centisome position: 31.09

GC content: 65.17

Gene sequence:

>870_bases
ATGAAACTCTGCGGATTCGAGGTTGGCCTCGACAAGCCGTTCTTTCTGATTGCCGGCCCGTGCGTGATCGAGTCGGAGCA
GATGGCGCTGGATACCGCCGGCGAACTCAAGGCCATCACCGGCGAGCTGGGTATTCCGTTCATCTACAAGTCGTCGTTCG
ACAAGGCGAACCGCTCGTCGGGCAAGTCGTTCCGCGGCCTTGGGATGGAAAAGGGCCTGGAAATCCTGGCGACAGTGAAG
CGCGAGATCGGGGTGCCGGTGCTCACCGACATCCATGAGATCGACGAGATCAAGCCCGTCGCGGCCGTCGTCGACGTGCT
GCAGACGCCGGCGTTCCTGTGCCGCCAGACTGATTTCATCCGCGCTTGCGCCCAGAGCGGCAAGCCTGTGAACATCAAGA
AGGGCCAGTTCCTCGCGCCGCACGACATGAAGAACGTGATCGACAAGGCCCGCGACGCCGCACGCGACGCCGGCCTGCCC
GACGACGTGTTCATGGCCTGCGAGCGTGGCGTTTCGTTCGGCTACAACAACCTGGTTTCGGACATGCGCTCGCTGGCGAT
CATGCGCGAGACCGGTGCTCCTGTGGTGTTTGACGCCACCCACTCGGTGCAACTGCCGGGCGGGCAGGGCACCAGCTCGG
GCGGCCAGCGCGAGTTCGTACCCGTACTGTCGCGTGCCGCCGTGGCCACCGGCATCGCCGGCCTGTTCATGGAAACGCAC
CCGGACCCGAACAAGGCCATGTCCGATGGCCCCAACGCGGTGCCGCTGTCGCGCATGAAGGAACTGCTGGCCGTGCTCAG
GGACCTGGACGCGCTGACCAAGCGCGCCGGCTTCCTCGAGGACAACTTCGGCTGGCCGGCCTGCGCCTGA

Upstream 100 bases:

>100_bases
CCGCGTGACGGCCATCCGCTGTTCAAGGCCTACGTCGAAGCCGCGCTGGCTGGCCAGCAGCGCAAGGGCGCCTGAAGCCG
GCGCCGAGCAGGAGACTGTC

Downstream 100 bases:

>100_bases
GCGGGCCCTGGATCGTCGCGGCCGGTGGCCCGGCCGTGACTATCCGTATCGAAAGACAATACAAAACATCGGGAGATACA
GCATGGCCGCGGGCTTTATC

Product: 2-dehydro-3-deoxyphosphooctonate aldolase

Products: NA

Alternate protein names: 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase; KDO-8-phosphate synthase; KDO 8-P synthase; KDOPS; Phospho-2-dehydro-3-deoxyoctonate aldolase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MKLCGFEVGLDKPFFLIAGPCVIESEQMALDTAGELKAITGELGIPFIYKSSFDKANRSSGKSFRGLGMEKGLEILATVK
REIGVPVLTDIHEIDEIKPVAAVVDVLQTPAFLCRQTDFIRACAQSGKPVNIKKGQFLAPHDMKNVIDKARDAARDAGLP
DDVFMACERGVSFGYNNLVSDMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLSRAAVATGIAGLFMETH
PDPNKAMSDGPNAVPLSRMKELLAVLRDLDALTKRAGFLEDNFGWPACA

Sequences:

>Translated_289_residues
MKLCGFEVGLDKPFFLIAGPCVIESEQMALDTAGELKAITGELGIPFIYKSSFDKANRSSGKSFRGLGMEKGLEILATVK
REIGVPVLTDIHEIDEIKPVAAVVDVLQTPAFLCRQTDFIRACAQSGKPVNIKKGQFLAPHDMKNVIDKARDAARDAGLP
DDVFMACERGVSFGYNNLVSDMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLSRAAVATGIAGLFMETH
PDPNKAMSDGPNAVPLSRMKELLAVLRDLDALTKRAGFLEDNFGWPACA
>Mature_289_residues
MKLCGFEVGLDKPFFLIAGPCVIESEQMALDTAGELKAITGELGIPFIYKSSFDKANRSSGKSFRGLGMEKGLEILATVK
REIGVPVLTDIHEIDEIKPVAAVVDVLQTPAFLCRQTDFIRACAQSGKPVNIKKGQFLAPHDMKNVIDKARDAARDAGLP
DDVFMACERGVSFGYNNLVSDMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLSRAAVATGIAGLFMETH
PDPNKAMSDGPNAVPLSRMKELLAVLRDLDALTKRAGFLEDNFGWPACA

Specific function: Synthesis Of Kdo 8-P Which Is Required For Lipid A Maturation And Cellular Growth. [C]

COG id: COG2877

COG function: function code M; 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsA family [H]

Homologues:

Organism=Escherichia coli, GI1787466, Length=275, Percent_Identity=44.3636363636364, Blast_Score=245, Evalue=2e-66,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006218
- InterPro:   IPR006269 [H]

Pfam domain/function: PF00793 DAHP_synth_1 [H]

EC number: =2.5.1.55 [H]

Molecular weight: Translated: 31014; Mature: 31014

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLCGFEVGLDKPFFLIAGPCVIESEQMALDTAGELKAITGELGIPFIYKSSFDKANRSS
CCCCCCCCCCCCCEEEEECCEEECCCHHHHCCCCHHHHHHHCCCCCEEECCCCCCCCCCC
GKSFRGLGMEKGLEILATVKREIGVPVLTDIHEIDEIKPVAAVVDVLQTPAFLCRQTDFI
CCCHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
RACAQSGKPVNIKKGQFLAPHDMKNVIDKARDAARDAGLPDDVFMACERGVSFGYNNLVS
HHHHHCCCCCEECCCCEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHH
DMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLSRAAVATGIAGLFMETH
HHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PDPNKAMSDGPNAVPLSRMKELLAVLRDLDALTKRAGFLEDNFGWPACA
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKLCGFEVGLDKPFFLIAGPCVIESEQMALDTAGELKAITGELGIPFIYKSSFDKANRSS
CCCCCCCCCCCCCEEEEECCEEECCCHHHHCCCCHHHHHHHCCCCCEEECCCCCCCCCCC
GKSFRGLGMEKGLEILATVKREIGVPVLTDIHEIDEIKPVAAVVDVLQTPAFLCRQTDFI
CCCHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHH
RACAQSGKPVNIKKGQFLAPHDMKNVIDKARDAARDAGLPDDVFMACERGVSFGYNNLVS
HHHHHCCCCCEECCCCEECCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHH
DMRSLAIMRETGAPVVFDATHSVQLPGGQGTSSGGQREFVPVLSRAAVATGIAGLFMETH
HHHHHHHHHHCCCCEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PDPNKAMSDGPNAVPLSRMKELLAVLRDLDALTKRAGFLEDNFGWPACA
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA