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The map label for this gene is glk [H]

Identifier: 73540782

GI number: 73540782

Start: 1172499

End: 1173455

Strand: Reverse

Name: glk [H]

Synonym: Reut_A1080

Alternate gene names: 73540782

Gene position: 1173455-1172499 (Counterclockwise)

Preceding gene: 73540795

Following gene: 73540777

Centisome position: 30.83

GC content: 68.86

Gene sequence:

>957_bases
ATGCCGGCGACACCCGCCACCGTCATGCGCGACCGAATCCTTGCCGTCTACGACACGCTCCGCCCGTCCGAACGCCGCCT
GGCCGACTATGTGGCCCGCCACGGCGCCAGCGTGATCCGGCTTTCGATGCCGGAACTGGCCGAGCGGGCCGGCGTGTCGC
AGCCGACCATTGCGCGTTTCTGCGCGGCGCTGGGCTACGACGGCTTCCGTGAATTCAAGCTGCAGTTCGCGCAAAACGTA
GGCGGCGGCACGCCGTTCGTCCACCAGGACGTGAAGGCCGAAGACGGCCCGGCCGACATAGCCGGCAAGGTGTTCGACCG
CACTATCGCCACGCTGATGAGCGTGCGCAATGCGCTGTCGGCGGACCAGATCGAGCACGGCATCCGCCTGCTGGCCCGTG
CGCGCCGCATCGAGTTCTACGGCTGCGGTAATTCCGGCATCGTCGCGCTCGATATCCAGCACAAGTTCTTCCGGCTGGGC
ATGCCCACTACGGCTTACTCCGATCCGCACGTATTCAGCATGTCCGCCGCGCTGCTCGGGCCTGGCGACGTGGCGGTACT
GGTTTCCAACAGCGGACGCACGTGGGACATGCTGACCGCCGCCACGCTGGCCCGCTCCAGCGGCGCAAGCGTGCTGGCGC
TCACGCACAGCGGCTCGCCGCTCGCGAAACTGGCCGACGTCTGCGTGTTTTCGGATGTGGAAGAGGACAGCGAGGTCTAT
ACGCCGATGACCTCACGCATCTGCCATCTCGTGCTCGGCGACGTGCTGGCAGCCGGAGTAGCGCTGGAACGCGCCGACAC
CGTCGCCGCGGGCCTGCAGCGCGCGAAGGCCCATCTGCGCGAGCGCCGCATTGGCGGCGCCGAGCCGGCGCGGGCGCCAC
AGGAAGCTGATACGCCAGAGCCGGCGGCGCCCGGGCGCAAGACGGCGTCGCGTGCACGCGCTCGCACCGCGAGCTAA

Upstream 100 bases:

>100_bases
TCAGTAACCCCCTTGAATACGGGAAATCCCTAGCGACAGAACAACAGAATCATCTGTGTTCCGCAGCCCTTCGGATTGTA
GAATATCTACATTCCCATTT

Downstream 100 bases:

>100_bases
CGCCACCTTCCGCTATCGCGGCGCTGCAGGCGCCTCACGCCAGTAGCGACGCTCGGCCTGGCGAAACGCTTCCATCGCAT
AGGCGTCACGGTGCGTGGTC

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Glucokinase; Glucose kinase; Putative HTH-type transcriptional regulator [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MPATPATVMRDRILAVYDTLRPSERRLADYVARHGASVIRLSMPELAERAGVSQPTIARFCAALGYDGFREFKLQFAQNV
GGGTPFVHQDVKAEDGPADIAGKVFDRTIATLMSVRNALSADQIEHGIRLLARARRIEFYGCGNSGIVALDIQHKFFRLG
MPTTAYSDPHVFSMSAALLGPGDVAVLVSNSGRTWDMLTAATLARSSGASVLALTHSGSPLAKLADVCVFSDVEEDSEVY
TPMTSRICHLVLGDVLAAGVALERADTVAAGLQRAKAHLRERRIGGAEPARAPQEADTPEPAAPGRKTASRARARTAS

Sequences:

>Translated_318_residues
MPATPATVMRDRILAVYDTLRPSERRLADYVARHGASVIRLSMPELAERAGVSQPTIARFCAALGYDGFREFKLQFAQNV
GGGTPFVHQDVKAEDGPADIAGKVFDRTIATLMSVRNALSADQIEHGIRLLARARRIEFYGCGNSGIVALDIQHKFFRLG
MPTTAYSDPHVFSMSAALLGPGDVAVLVSNSGRTWDMLTAATLARSSGASVLALTHSGSPLAKLADVCVFSDVEEDSEVY
TPMTSRICHLVLGDVLAAGVALERADTVAAGLQRAKAHLRERRIGGAEPARAPQEADTPEPAAPGRKTASRARARTAS
>Mature_317_residues
PATPATVMRDRILAVYDTLRPSERRLADYVARHGASVIRLSMPELAERAGVSQPTIARFCAALGYDGFREFKLQFAQNVG
GGTPFVHQDVKAEDGPADIAGKVFDRTIATLMSVRNALSADQIEHGIRLLARARRIEFYGCGNSGIVALDIQHKFFRLGM
PTTAYSDPHVFSMSAALLGPGDVAVLVSNSGRTWDMLTAATLARSSGASVLALTHSGSPLAKLADVCVFSDVEEDSEVYT
PMTSRICHLVLGDVLAAGVALERADTVAAGLQRAKAHLRERRIGGAEPARAPQEADTPEPAAPGRKTASRARARTAS

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=277, Percent_Identity=39.3501805054152, Blast_Score=203, Evalue=1e-53,
Organism=Escherichia coli, GI87082369, Length=259, Percent_Identity=31.2741312741313, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI87082130, Length=243, Percent_Identity=27.9835390946502, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788767, Length=247, Percent_Identity=24.6963562753036, Blast_Score=88, Evalue=8e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836
- InterPro:   IPR000843
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02685 Glucokinase; PF01418 HTH_6; PF01380 SIS [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33923; Mature: 33792

Theoretical pI: Translated: 8.63; Mature: 8.63

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPATPATVMRDRILAVYDTLRPSERRLADYVARHGASVIRLSMPELAERAGVSQPTIARF
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCCHHHHHH
CAALGYDGFREFKLQFAQNVGGGTPFVHQDVKAEDGPADIAGKVFDRTIATLMSVRNALS
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADQIEHGIRLLARARRIEFYGCGNSGIVALDIQHKFFRLGMPTTAYSDPHVFSMSAALLG
HHHHHHHHHHHHHHHHEEEEECCCCCEEEEEECHHHHHCCCCCCCCCCCCEEEHHHHHCC
PGDVAVLVSNSGRTWDMLTAATLARSSGASVLALTHSGSPLAKLADVCVFSDVEEDSEVY
CCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCHHH
TPMTSRICHLVLGDVLAAGVALERADTVAAGLQRAKAHLRERRIGGAEPARAPQEADTPE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PAAPGRKTASRARARTAS
CCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
PATPATVMRDRILAVYDTLRPSERRLADYVARHGASVIRLSMPELAERAGVSQPTIARF
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEECCHHHHHHCCCCCHHHHHH
CAALGYDGFREFKLQFAQNVGGGTPFVHQDVKAEDGPADIAGKVFDRTIATLMSVRNALS
HHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
ADQIEHGIRLLARARRIEFYGCGNSGIVALDIQHKFFRLGMPTTAYSDPHVFSMSAALLG
HHHHHHHHHHHHHHHHEEEEECCCCCEEEEEECHHHHHCCCCCCCCCCCCEEEHHHHHCC
PGDVAVLVSNSGRTWDMLTAATLARSSGASVLALTHSGSPLAKLADVCVFSDVEEDSEVY
CCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCHHH
TPMTSRICHLVLGDVLAAGVALERADTVAAGLQRAKAHLRERRIGGAEPARAPQEADTPE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PAAPGRKTASRARARTAS
CCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA