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The map label for this gene is iscR [H]

Identifier: 73540759

GI number: 73540759

Start: 1149837

End: 1150397

Strand: Direct

Name: iscR [H]

Synonym: Reut_A1057

Alternate gene names: 73540759

Gene position: 1149837-1150397 (Clockwise)

Preceding gene: 73540758

Following gene: 73540760

Centisome position: 30.21

GC content: 64.71

Gene sequence:

>561_bases
ATGAGACTGACCACCAAAGGCCGCTTTGCGGTCACTGCGATGATCGACCTGGCCATGCGCCAGGACCAGGGGCCCGTCAC
GCTCGCGGGCATCAGCCAGCGGCAGAAGATCTCGCTGTCCTACCTGGAACAGCTGTTCGGCAAGCTGCGCCGGCATGAGA
TCGTCGAAAGCGTGCGCGGACCGGGCGGTGGCTACAGCCTCGCGCGCAAGGCGGAAGACGTCACCGTGGCGGACATCATC
ATCGCCGTGGACGAGCCGCTTGATGCCACCCAGTGCGGTGGAAAGGGCAATTGTAACGGAGATGACGGCTCCGGGCGTTG
CATGACCCACGAGCTGTGGGCGACGCTGAACCAGAAAATGGTCGAATATCTCGATTCCGTCTCCCTCAAGAACCTGGTGG
ACCAGCAGCGCGCCAAGCAGCCGGCCGTCCTGCACGACATGCGCGAAGACGCTGCCGTGCAGCAGGCGGCACCCGCGGCG
CGCGGCAAGGCGGAAAAGGCCGCCGAAAAGCCGGTCCGTGCCCGGATGGTGAATTCGGTTTTCAGCCTGGCGCAGTCCTG
A

Upstream 100 bases:

>100_bases
GGGCGGCCGCCGGGTTTGATGCGGTGCCGTAGGGGTAGTTGACTGAAATAGTCGGGTACCTTTATACTTGACGGAAACGA
TCAAGTATTAGCCCTGCATC

Downstream 100 bases:

>100_bases
AGCGCCCGGTAGCAAGCAGCGATACAAGCGATCAGCGGTCCCCCTGAAAAAGGCAGTCATAACGATGAGCACCCCACATT
TCCCCATCTACATGGATTAC

Product: BadM/Rrf2 family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRGPGGGYSLARKAEDVTVADII
IAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKMVEYLDSVSLKNLVDQQRAKQPAVLHDMREDAAVQQAAPAA
RGKAEKAAEKPVRARMVNSVFSLAQS

Sequences:

>Translated_186_residues
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRGPGGGYSLARKAEDVTVADII
IAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKMVEYLDSVSLKNLVDQQRAKQPAVLHDMREDAAVQQAAPAA
RGKAEKAAEKPVRARMVNSVFSLAQS
>Mature_186_residues
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRGPGGGYSLARKAEDVTVADII
IAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKMVEYLDSVSLKNLVDQQRAKQPAVLHDMREDAAVQQAAPAA
RGKAEKAAEKPVRARMVNSVFSLAQS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=136, Percent_Identity=53.6764705882353, Blast_Score=139, Evalue=2e-34,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 20209; Mature: 20209

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYSLARKAEDVTVADIIIAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKM
CCCCHHHHHHCCCCCHHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VEYLDSVSLKNLVDQQRAKQPAVLHDMREDAAVQQAAPAARGKAEKAAEKPVRARMVNSV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHH
FSLAQS
HHHHCC
>Mature Secondary Structure
MRLTTKGRFAVTAMIDLAMRQDQGPVTLAGISQRQKISLSYLEQLFGKLRRHEIVESVRG
CCCCCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGGYSLARKAEDVTVADIIIAVDEPLDATQCGGKGNCNGDDGSGRCMTHELWATLNQKM
CCCCHHHHHHCCCCCHHHEEEECCCCCCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
VEYLDSVSLKNLVDQQRAKQPAVLHDMREDAAVQQAAPAARGKAEKAAEKPVRARMVNSV
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHHHHHH
FSLAQS
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]