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The map label for this gene is nahR [H]

Identifier: 73540706

GI number: 73540706

Start: 1090049

End: 1090996

Strand: Direct

Name: nahR [H]

Synonym: Reut_A1003

Alternate gene names: 73540706

Gene position: 1090049-1090996 (Clockwise)

Preceding gene: 73540703

Following gene: 73540707

Centisome position: 28.64

GC content: 66.67

Gene sequence:

>948_bases
ATGGGAGCCATGCAGCTATCCCGCATCGACCTCAATCTCTTCGTGGTGTTCGACGCTATCTATAGCGAAGGCAGCATCAC
CGCGGCGGCTCGTCAGCTCAACCTGACGCAGCCGGCGGTGAGTCACGCGCTGGGCCGCCTGCGCGGCCTGTTCGATGATC
CGCTGTTCGAGCGGCGCGGGCAGGGCATGGCGCCCACGCCGCTGGCACGCTCGCTCGCATCGGAGGTCCGCTCGGCGCTG
CAGTCCTTTGCGCGCACCCTGCAGGACACGCCGCACTTCGATCCGACCAACACTGTGCGCCGCTTCACCATTGGCATGCG
CGACGCGCTGGAATCCACGCTGCTGCCGCCGCTGATGGCGCGCGTGACCTCGGTGGCGCCGCAGGTGGAGATTGCCGCGA
TCCGGTTCGACCGGCGCGAGATGGAATCCGAACTGCTGGCCGGCACGATCGATGCTGCCATCGATATCCTGCTGCCAGTG
TCGCCGGCCATCCATCATGCCCAGTTCATGGCCGATCCGATGATCGTGCTGGCGCGCCGCGACCATCCGCTTGTAAAGAA
AGAGCTGACGCTGGAACGCTACCTGGCTGCCGAGCACGTTCACGTGTCCTCGCGGCGCCGTGGTGCGGGGCTGGAGGATC
AGGCGCTGCACCGCATGGGGCTGACGCGCCGGGTGCGGCTGCGCTGCCAGCACTATGCCGCGGCCTGCCGCGTGGTGAGC
TGTACGGACCTGCTCGCAACGCTGCCGCTGCGTTATGCGCGCATCGCCAATGAACCTTATGCCAACCGCATCCTGTCGCT
GCCGTTCAAGGTACCGTCGCTCGAGCTGCATTTGTACTGGCATGCAGGCGGCGAAAACGATGGCGCCAATCGCTGGCTGC
GCGAGCAACTCATGGCGGTGATGTCCTCGCTCGGCGGCGGCGTGCCCGAAGCGCAGTCGGCGGTCTGA

Upstream 100 bases:

>100_bases
GCGGCATATGCCGATGGAAAGCACTCTATCCGAAACCTGGTAATAACAAAAATGAATTTTCTGGATTTGTCAGTATCAAT
GTCCTGCATTCCGTGCCAGA

Downstream 100 bases:

>100_bases
CGTCGCCTGGTGCAGCGCGCGTGGGTCACACGTAAGCCATTGTTAGCGGGCTGGACGCTCGCTGACCGTCTCCCTACCAT
CACCGGGTCACATCTGCCCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MGAMQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRGLFDDPLFERRGQGMAPTPLARSLASEVRSAL
QSFARTLQDTPHFDPTNTVRRFTIGMRDALESTLLPPLMARVTSVAPQVEIAAIRFDRREMESELLAGTIDAAIDILLPV
SPAIHHAQFMADPMIVLARRDHPLVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVS
CTDLLATLPLRYARIANEPYANRILSLPFKVPSLELHLYWHAGGENDGANRWLREQLMAVMSSLGGGVPEAQSAV

Sequences:

>Translated_315_residues
MGAMQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRGLFDDPLFERRGQGMAPTPLARSLASEVRSAL
QSFARTLQDTPHFDPTNTVRRFTIGMRDALESTLLPPLMARVTSVAPQVEIAAIRFDRREMESELLAGTIDAAIDILLPV
SPAIHHAQFMADPMIVLARRDHPLVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVS
CTDLLATLPLRYARIANEPYANRILSLPFKVPSLELHLYWHAGGENDGANRWLREQLMAVMSSLGGGVPEAQSAV
>Mature_314_residues
GAMQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRGLFDDPLFERRGQGMAPTPLARSLASEVRSALQ
SFARTLQDTPHFDPTNTVRRFTIGMRDALESTLLPPLMARVTSVAPQVEIAAIRFDRREMESELLAGTIDAAIDILLPVS
PAIHHAQFMADPMIVLARRDHPLVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVSC
TDLLATLPLRYARIANEPYANRILSLPFKVPSLELHLYWHAGGENDGANRWLREQLMAVMSSLGGGVPEAQSAV

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=296, Percent_Identity=29.7297297297297, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87081766, Length=270, Percent_Identity=27.7777777777778, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790147, Length=302, Percent_Identity=25.4966887417219, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1786820, Length=285, Percent_Identity=23.859649122807, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787601, Length=249, Percent_Identity=23.2931726907631, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34925; Mature: 34794

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAMQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRGLFDDPLFERRG
CCCCEEEHCCEEEEEEEEHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCC
QGMAPTPLARSLASEVRSALQSFARTLQDTPHFDPTNTVRRFTIGMRDALESTLLPPLMA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHH
RVTSVAPQVEIAAIRFDRREMESELLAGTIDAAIDILLPVSPAIHHAQFMADPMIVLARR
HHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEC
DHPLVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHH
CTDLLATLPLRYARIANEPYANRILSLPFKVPSLELHLYWHAGGENDGANRWLREQLMAV
HHHHHHHHHHHHHHHCCCHHHHHHEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
MSSLGGGVPEAQSAV
HHHHCCCCCCHHCCC
>Mature Secondary Structure 
GAMQLSRIDLNLFVVFDAIYSEGSITAAARQLNLTQPAVSHALGRLRGLFDDPLFERRG
CCCEEEHCCEEEEEEEEHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHCC
QGMAPTPLARSLASEVRSALQSFARTLQDTPHFDPTNTVRRFTIGMRDALESTLLPPLMA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHH
RVTSVAPQVEIAAIRFDRREMESELLAGTIDAAIDILLPVSPAIHHAQFMADPMIVLARR
HHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEEC
DHPLVKKELTLERYLAAEHVHVSSRRRGAGLEDQALHRMGLTRRVRLRCQHYAAACRVVS
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHH
CTDLLATLPLRYARIANEPYANRILSLPFKVPSLELHLYWHAGGENDGANRWLREQLMAV
HHHHHHHHHHHHHHHCCCHHHHHHEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHH
MSSLGGGVPEAQSAV
HHHHCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]