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The map label for this gene is yngJ [H]

Identifier: 73540682

GI number: 73540682

Start: 1067254

End: 1068372

Strand: Direct

Name: yngJ [H]

Synonym: Reut_A0979

Alternate gene names: 73540682

Gene position: 1067254-1068372 (Clockwise)

Preceding gene: 73540681

Following gene: 73540683

Centisome position: 28.04

GC content: 65.95

Gene sequence:

>1119_bases
ATGAACTTCAATCTCAGCGACGAACAGAAGCAACTGGCTGACGCCGTACGCCGTTTCATCGACAAGGACTACGACTTCGA
GTCGCGCAAGAAGCGCTACGAGAGTGCAGCCGGCTACGGCGAGAATACGTGGGGCGCGCTGGTCGAGCTCGGCCTGACCG
CGCTGCCGGTGCCGGAAGAGCAGGGCGGCTTCGCGGGCAAGGCGCTGGACATGATGGTGGTGCAGCAGGAACTCGGCCGC
GGCCTGATCGTGGAGCCGTACCTCGCGACCGTGGTCGGCGCGTATGCGCTGGGCCTGGCCGGTGGCCAGGAAGCGCTGCT
CGAGCAGGTTGCAGGCGGTGAGCTGAAGCTGGCGGTAGCCTTCAATGAGCCGCAGGCGCGCTATGAGCTGAACAACGTCC
GCGTGACCGCGCGCGACGGCAAGCTCAATGGCCGCAAGTCGGTGGTGATTCACGGCGGCCAGGCTGACAAGCTGATCGTG
TCGGCACGCAGCAACGGTGCGGATGCCGATCGCGATGGCATCTCGCTGTTCCTCGTCGATGCCAAGGGTGTCGGCGTCAG
CATCAAGGACTACCGCACCATCGACAACCTGCGCGCGGCCGATATCACGTTCCAGGATGCGCCGGCTCAACTGCTCGGCG
AGGCCGGCAAGGCTTTCGACCAGGTCGAGCAGGTGGCGGACTACGCCGCGGTGCTGCTGTGCGCCGAGGCCGTGGGCGTC
ATGGACAACCTCAACGCCGCCACGCTGGAATACGCCAAGACGCGCCAGCAGTTCGGCCAGCCGATTGCGCGTTTTCAGGC
GCTGCAGCACCGCATGGTCGAGATGTTCATCCATGCCGAGCAGTCGCGCTCGATCACGCTGCTGGCAGCGGCCCGCTTCG
AGGAGAGCAACCCCGAAGAGCGCCGCCGCTACGTCTCGGCCGCCAAGGCACGGGTCGGCCAGGCCGCGCGCTATGTCGGC
CAGGAAGCCGTGCAGATCCACGGTGGCATGGGCGTGACCAACGAACTGCCGGCCGCGCACATGTTCAAGCGCCTGACGCT
GATCAACACCACGTTCGGTGACGTGGATCATCACCTGGGCCGGTTCGCCGGCCAGGCAAGCTTCCAGGAAGCTGCCTGA

Upstream 100 bases:

>100_bases
TACTTCAACTATCGCAAGACCTCCATCTACGGCGGGTCCAATGAAATCCAGCGCAACATCATCAGCCAGATGATCCTGGG
GCTGTGAGGAGACACGGAAC

Downstream 100 bases:

>100_bases
TCCAGTGATGACTGTCGAAACCGCGCCGTAGTCCAGGCGCGGTTTTTTCTTTATGGGCTGTTAGGGGCGGCTTCGGCAAA
TACGGACGCACGCCGTCACG

Product: Acyl-CoA dehydrogenase, C-terminal

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MNFNLSDEQKQLADAVRRFIDKDYDFESRKKRYESAAGYGENTWGALVELGLTALPVPEEQGGFAGKALDMMVVQQELGR
GLIVEPYLATVVGAYALGLAGGQEALLEQVAGGELKLAVAFNEPQARYELNNVRVTARDGKLNGRKSVVIHGGQADKLIV
SARSNGADADRDGISLFLVDAKGVGVSIKDYRTIDNLRAADITFQDAPAQLLGEAGKAFDQVEQVADYAAVLLCAEAVGV
MDNLNAATLEYAKTRQQFGQPIARFQALQHRMVEMFIHAEQSRSITLLAAARFEESNPEERRRYVSAAKARVGQAARYVG
QEAVQIHGGMGVTNELPAAHMFKRLTLINTTFGDVDHHLGRFAGQASFQEAA

Sequences:

>Translated_372_residues
MNFNLSDEQKQLADAVRRFIDKDYDFESRKKRYESAAGYGENTWGALVELGLTALPVPEEQGGFAGKALDMMVVQQELGR
GLIVEPYLATVVGAYALGLAGGQEALLEQVAGGELKLAVAFNEPQARYELNNVRVTARDGKLNGRKSVVIHGGQADKLIV
SARSNGADADRDGISLFLVDAKGVGVSIKDYRTIDNLRAADITFQDAPAQLLGEAGKAFDQVEQVADYAAVLLCAEAVGV
MDNLNAATLEYAKTRQQFGQPIARFQALQHRMVEMFIHAEQSRSITLLAAARFEESNPEERRRYVSAAKARVGQAARYVG
QEAVQIHGGMGVTNELPAAHMFKRLTLINTTFGDVDHHLGRFAGQASFQEAA
>Mature_372_residues
MNFNLSDEQKQLADAVRRFIDKDYDFESRKKRYESAAGYGENTWGALVELGLTALPVPEEQGGFAGKALDMMVVQQELGR
GLIVEPYLATVVGAYALGLAGGQEALLEQVAGGELKLAVAFNEPQARYELNNVRVTARDGKLNGRKSVVIHGGQADKLIV
SARSNGADADRDGISLFLVDAKGVGVSIKDYRTIDNLRAADITFQDAPAQLLGEAGKAFDQVEQVADYAAVLLCAEAVGV
MDNLNAATLEYAKTRQQFGQPIARFQALQHRMVEMFIHAEQSRSITLLAAARFEESNPEERRRYVSAAKARVGQAARYVG
QEAVQIHGGMGVTNELPAAHMFKRLTLINTTFGDVDHHLGRFAGQASFQEAA

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=317, Percent_Identity=28.0757097791798, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI4501857, Length=361, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI21361497, Length=368, Percent_Identity=25.8152173913043, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI4557235, Length=359, Percent_Identity=26.1838440111421, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI76496475, Length=359, Percent_Identity=26.1838440111421, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI226958412, Length=359, Percent_Identity=24.2339832869081, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI226958414, Length=320, Percent_Identity=25.625, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI187960098, Length=369, Percent_Identity=25.4742547425474, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI4557231, Length=369, Percent_Identity=25.4742547425474, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1786223, Length=359, Percent_Identity=25.0696378830084, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87081958, Length=370, Percent_Identity=23.5135135135135, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17538396, Length=361, Percent_Identity=26.0387811634349, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17569725, Length=365, Percent_Identity=27.9452054794521, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534899, Length=367, Percent_Identity=28.0653950953678, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17506239, Length=358, Percent_Identity=24.0223463687151, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508101, Length=373, Percent_Identity=24.9329758713137, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71985184, Length=364, Percent_Identity=25.5494505494505, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17570075, Length=373, Percent_Identity=25.201072386059, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=355, Percent_Identity=24.7887323943662, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17505929, Length=313, Percent_Identity=27.1565495207668, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI21356377, Length=362, Percent_Identity=25.9668508287293, Blast_Score=101, Evalue=7e-22,
Organism=Drosophila melanogaster, GI21355753, Length=354, Percent_Identity=27.683615819209, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24660351, Length=370, Percent_Identity=27.8378378378378, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281363737, Length=352, Percent_Identity=25.5681818181818, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646207, Length=364, Percent_Identity=25.8241758241758, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24666513, Length=378, Percent_Identity=23.015873015873, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 40405; Mature: 40405

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFNLSDEQKQLADAVRRFIDKDYDFESRKKRYESAAGYGENTWGALVELGLTALPVPEE
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
QGGFAGKALDMMVVQQELGRGLIVEPYLATVVGAYALGLAGGQEALLEQVAGGELKLAVA
CCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEE
FNEPQARYELNNVRVTARDGKLNGRKSVVIHGGQADKLIVSARSNGADADRDGISLFLVD
ECCCCHHEEECCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEE
AKGVGVSIKDYRTIDNLRAADITFQDAPAQLLGEAGKAFDQVEQVADYAAVLLCAEAVGV
CCCCCEEHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDNLNAATLEYAKTRQQFGQPIARFQALQHRMVEMFIHAEQSRSITLLAAARFEESNPEE
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHH
RRRYVSAAKARVGQAARYVGQEAVQIHGGMGVTNELPAAHMFKRLTLINTTFGDVDHHLG
HHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
RFAGQASFQEAA
HHHCCCCHHCCC
>Mature Secondary Structure
MNFNLSDEQKQLADAVRRFIDKDYDFESRKKRYESAAGYGENTWGALVELGLTALPVPEE
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCC
QGGFAGKALDMMVVQQELGRGLIVEPYLATVVGAYALGLAGGQEALLEQVAGGELKLAVA
CCCCCHHHHHHHHHHHHHCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEE
FNEPQARYELNNVRVTARDGKLNGRKSVVIHGGQADKLIVSARSNGADADRDGISLFLVD
ECCCCHHEEECCEEEEEECCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCEEEEEE
AKGVGVSIKDYRTIDNLRAADITFQDAPAQLLGEAGKAFDQVEQVADYAAVLLCAEAVGV
CCCCCEEHHHHHHHHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDNLNAATLEYAKTRQQFGQPIARFQALQHRMVEMFIHAEQSRSITLLAAARFEESNPEE
HHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHH
RRRYVSAAKARVGQAARYVGQEAVQIHGGMGVTNELPAAHMFKRLTLINTTFGDVDHHLG
HHHHHHHHHHHHHHHHHHHCHHHEEEECCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHH
RFAGQASFQEAA
HHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9387222; 9384377 [H]