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The map label for this gene is ndh [H]

Identifier: 73540577

GI number: 73540577

Start: 950855

End: 952189

Strand: Direct

Name: ndh [H]

Synonym: Reut_A0874

Alternate gene names: 73540577

Gene position: 950855-952189 (Clockwise)

Preceding gene: 73540576

Following gene: 73540578

Centisome position: 24.98

GC content: 67.12

Gene sequence:

>1335_bases
ATGACCACAGGAGCAAACGGCAGGGCGCATCGCATCATCGTCGTAGGGGGCGGGGCAGGAGGACTGGAGCTGGTGACACG
GCTGGGCGACAAGCTCGGCAAGAAGGGCACCGCGCAAGTGGTGCTCGTGGACCGCTTGCCCACGCATATCTGGAAACCGC
TGCTGCATGAAGTTGCCGCGGGCAGCATGGATCCCAACACGCACCAGCTCGAATACGTGGCGCAGGCGCGCTGGCATCAC
TTCGAGTTCCAGCAGGGTGAAATGACCGGCATCGACCGCGAGCGCAAGACGATCTCGGTTGCGGCGTGCCTCGACCCCGA
CGGTGGCGAGCTGTTGCCGGCGCGGGAGCTGCCTTACGACACGCTTGTGCTGGCCATCGGGTGCGTGACGCATTTCTTCG
GCGTGCCGGGTGCGGCGGAGCATGCGATTGCGCTCGATACCGTCGCACAGGCCGAGCGCTTCCGCCGTCGTCTGATCGCG
GCCTGCGTGCGCGCGCAAAACGGACGCGGGCGCGTTGGCGAGGACGGCCGGCCGCGCGTGGACGTGGCCATCATCGGCGC
CGGTGCGACCGGCGTGGAACTGTCGGCAGAGCTGCGCAACACCGCGCATGTGCTCAACGCCTACGGACTGCACAAGCTCG
ATCCGCGCCGCGACGTGCGCATTCACGTGATCGAGGCTGGCCCGCGCATCCTGCCTGCGCTATCGGAGCGGGTCTCGGCC
GAAACCGCAAAGTTGCTGCGCAAGCTCGACGTCGATGTCTTCACCAGCGAGCGCGTGACCGAGGTCAACACCGAAGCCGT
GCTGACTGCGAGTGGCAAGCGCATCGATGCCGACTTGACGGTGTGGGCGGCGGGCATTACCGCGCCGCCGGTGCTGGCGA
CGCTTGGGTTGCCGGTCAGCCGGCAAGGCCAGATCCTCGTGCGGCCTACACTGCAGAGCGAAGGCGACCCCGACATCTTC
GCGTTCGGCGATTGCGCGAGCTGCCCGTGGCCCGAGAAGCAGACTGCGGTGCCGCCGCGCGCGCAGGCCGCGCATCAGCA
GGCGACGTTCCTGTTCGACGCACTGCGCGCACGCCTTGCCGGCAAGCCGTTGCCGGAATTCGCGTTCAAGGACTTCGGCT
CGTTGGTATCGCTCGGGCATTTCAGCGCGGTGGGTAGCCTGATGGGCGGGCTCATCGGCGGGTCGATGTTCATCGAAGGG
CTGATGGCGCGCTTCATGTACACCTCGCTCTACCGCATGCATGTGCTGGCGCTTCACGGCGCGGTCGGCATGGGGCTCGA
CACGGTGACGCACTGGTTGCGCAGCAAGACCAGCCCGCGCGTGAAGCTGCACTGA

Upstream 100 bases:

>100_bases
ATCGGTGATTGCTGTCTTGCTTCAGCTGCTGCGATGCAGCAAACTGGGGGCAAATGCCTAACGGCCAGCGTTTCTCAGCA
ATAAAAGCATCGGGTAGACC

Downstream 100 bases:

>100_bases
GCGGCGCCCGCGTGCCGGCCGGTGCACGTGACGGCATGTTTGCTTAGAATCGTCAGTTGGCGCCGGTGGGACTTCCCCGG
CGGACACCCAACCGACAACG

Product: NADH dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTTGANGRAHRIIVVGGGAGGLELVTRLGDKLGKKGTAQVVLVDRLPTHIWKPLLHEVAAGSMDPNTHQLEYVAQARWHH
FEFQQGEMTGIDRERKTISVAACLDPDGGELLPARELPYDTLVLAIGCVTHFFGVPGAAEHAIALDTVAQAERFRRRLIA
ACVRAQNGRGRVGEDGRPRVDVAIIGAGATGVELSAELRNTAHVLNAYGLHKLDPRRDVRIHVIEAGPRILPALSERVSA
ETAKLLRKLDVDVFTSERVTEVNTEAVLTASGKRIDADLTVWAAGITAPPVLATLGLPVSRQGQILVRPTLQSEGDPDIF
AFGDCASCPWPEKQTAVPPRAQAAHQQATFLFDALRARLAGKPLPEFAFKDFGSLVSLGHFSAVGSLMGGLIGGSMFIEG
LMARFMYTSLYRMHVLALHGAVGMGLDTVTHWLRSKTSPRVKLH

Sequences:

>Translated_444_residues
MTTGANGRAHRIIVVGGGAGGLELVTRLGDKLGKKGTAQVVLVDRLPTHIWKPLLHEVAAGSMDPNTHQLEYVAQARWHH
FEFQQGEMTGIDRERKTISVAACLDPDGGELLPARELPYDTLVLAIGCVTHFFGVPGAAEHAIALDTVAQAERFRRRLIA
ACVRAQNGRGRVGEDGRPRVDVAIIGAGATGVELSAELRNTAHVLNAYGLHKLDPRRDVRIHVIEAGPRILPALSERVSA
ETAKLLRKLDVDVFTSERVTEVNTEAVLTASGKRIDADLTVWAAGITAPPVLATLGLPVSRQGQILVRPTLQSEGDPDIF
AFGDCASCPWPEKQTAVPPRAQAAHQQATFLFDALRARLAGKPLPEFAFKDFGSLVSLGHFSAVGSLMGGLIGGSMFIEG
LMARFMYTSLYRMHVLALHGAVGMGLDTVTHWLRSKTSPRVKLH
>Mature_443_residues
TTGANGRAHRIIVVGGGAGGLELVTRLGDKLGKKGTAQVVLVDRLPTHIWKPLLHEVAAGSMDPNTHQLEYVAQARWHHF
EFQQGEMTGIDRERKTISVAACLDPDGGELLPARELPYDTLVLAIGCVTHFFGVPGAAEHAIALDTVAQAERFRRRLIAA
CVRAQNGRGRVGEDGRPRVDVAIIGAGATGVELSAELRNTAHVLNAYGLHKLDPRRDVRIHVIEAGPRILPALSERVSAE
TAKLLRKLDVDVFTSERVTEVNTEAVLTASGKRIDADLTVWAAGITAPPVLATLGLPVSRQGQILVRPTLQSEGDPDIFA
FGDCASCPWPEKQTAVPPRAQAAHQQATFLFDALRARLAGKPLPEFAFKDFGSLVSLGHFSAVGSLMGGLIGGSMFIEGL
MARFMYTSLYRMHVLALHGAVGMGLDTVTHWLRSKTSPRVKLH

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=435, Percent_Identity=49.8850574712644, Blast_Score=394, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6323515, Length=475, Percent_Identity=24.2105263157895, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323794, Length=364, Percent_Identity=26.6483516483516, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6320118, Length=467, Percent_Identity=22.6980728051392, Blast_Score=84, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 47818; Mature: 47687

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTGANGRAHRIIVVGGGAGGLELVTRLGDKLGKKGTAQVVLVDRLPTHIWKPLLHEVAA
CCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHC
GSMDPNTHQLEYVAQARWHHFEFQQGEMTGIDRERKTISVAACLDPDGGELLPARELPYD
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHH
TLVLAIGCVTHFFGVPGAAEHAIALDTVAQAERFRRRLIAACVRAQNGRGRVGEDGRPRV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
DVAIIGAGATGVELSAELRNTAHVLNAYGLHKLDPRRDVRIHVIEAGPRILPALSERVSA
EEEEEECCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
ETAKLLRKLDVDVFTSERVTEVNTEAVLTASGKRIDADLTVWAAGITAPPVLATLGLPVS
HHHHHHHHHCCCCCCCCCCEECCCCEEEEECCCEECCCEEEEEECCCCCHHHHHHCCCCC
RQGQILVRPTLQSEGDPDIFAFGDCASCPWPEKQTAVPPRAQAAHQQATFLFDALRARLA
CCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GKPLPEFAFKDFGSLVSLGHFSAVGSLMGGLIGGSMFIEGLMARFMYTSLYRMHVLALHG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGMGLDTVTHWLRSKTSPRVKLH
HHHCCHHHHHHHHHCCCCCCEEEC
>Mature Secondary Structure 
TTGANGRAHRIIVVGGGAGGLELVTRLGDKLGKKGTAQVVLVDRLPTHIWKPLLHEVAA
CCCCCCCEEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHC
GSMDPNTHQLEYVAQARWHHFEFQQGEMTGIDRERKTISVAACLDPDGGELLPARELPYD
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCHH
TLVLAIGCVTHFFGVPGAAEHAIALDTVAQAERFRRRLIAACVRAQNGRGRVGEDGRPRV
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
DVAIIGAGATGVELSAELRNTAHVLNAYGLHKLDPRRDVRIHVIEAGPRILPALSERVSA
EEEEEECCCCCCEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHH
ETAKLLRKLDVDVFTSERVTEVNTEAVLTASGKRIDADLTVWAAGITAPPVLATLGLPVS
HHHHHHHHHCCCCCCCCCCEECCCCEEEEECCCEECCCEEEEEECCCCCHHHHHHCCCCC
RQGQILVRPTLQSEGDPDIFAFGDCASCPWPEKQTAVPPRAQAAHQQATFLFDALRARLA
CCCCEEEEECCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
GKPLPEFAFKDFGSLVSLGHFSAVGSLMGGLIGGSMFIEGLMARFMYTSLYRMHVLALHG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVGMGLDTVTHWLRSKTSPRVKLH
HHHCCHHHHHHHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]