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The map label for this gene is ltaE [H]

Identifier: 73540562

GI number: 73540562

Start: 929712

End: 930752

Strand: Direct

Name: ltaE [H]

Synonym: Reut_A0859

Alternate gene names: 73540562

Gene position: 929712-930752 (Clockwise)

Preceding gene: 73540561

Following gene: 73540563

Centisome position: 24.42

GC content: 63.5

Gene sequence:

>1041_bases
ATGACCAAGCAGCATTTCGCCTCGGACAACTACGCCGGCTTTTGTCCGGAGTCGCTGAAGTATTTCCTCGAAGCCAACGG
CACGGGCCACGAACAGGCCTATGGCGACGATTCCTGGACCCAGAAAGTCTGCGACCGGATCCGCGACCTGTTCCAGACCG
ATTGCGAAGTGTTCTTCGTCTTCAACGGCACGGCAGCAAACTCCCTCGCGCTATCGGCGCTGTGCCAGTCGTACCACTCG
GTCATCTGCCACGAACTGGCGCATATCGAGACCGACGAGTGCGGCGGGCCGGAGTTCTTCTCCAACGGCTCCAAGCTGCT
GACCGCGCCGGGCGAGAACGGCAAGCTCACGCCCGATGCGATCGAGGCACTGGTCACGCGCCGCTCGGACATCCACTACC
CGAAGCCTAAGGTGGTGTCTCTGACGCAGTCGACCGAAGTCGGCACCGTCTATACGGTGGAGGAGGTTAGGGCGATTGCC
GCCATCGCCAAGCGCCGCCAGCTTCGCGTTCACATGGACGGCGCGCGTTTTGCCAATGCGGTGGCTTCGCTCGGCGTGCA
TCCGTCCGAGATCACGTGGCGCGCCGGCGTGGATGTACTGTGCTTCGGCGGCACCAAGAACGGACTGCCGGTGGGCGAGG
CGGTGGTCTTCTTCGATCGCCGCCTGGCCGAGGACTTTGCCTACCGCGTCAAGCAGGCTGGCCAGCTTGCATCGAAGATG
CGTTTCATCTCGGCGCCGTGGCTCGGACTGCTGGAAAACAACGTCTGGCTGTCCAACGCGCGGCATGCCAATGCCATGGC
GCAGCTGCTGCAGTCACGCATTGCAGATTTCCCGGGCGTGCGCATCATGTTCCCGACCGAGTCCAACGCGGTGTTCGCCG
AACTGCCGCTGCCAGCGATTGAGGCATTGCGCGCAAAGGGCTGGCGCTTCTATACGTTCATCGGTGCGGGCGGCTGCCGC
TTTATGTGTGCGTGGGACCTGCAGCCTGAGACGGTCGAGGCGCTTGCGGCCGACATGCACGTGGCCTGCGCAGCCTGCTG
A

Upstream 100 bases:

>100_bases
ATCATCATCACCGACGTCAAGCGCGAGAACTGGGCCACCGGCGGCGAGCTGTGGGCCGACAAGAAGTAACCGCACCAGCC
ACACACCGCAAGACCCGCCT

Downstream 100 bases:

>100_bases
AAGTCGCACTCAGGCGTAAGATACCGGGCGGTAGCAGAACATAACGAGACACCGAGGAGCTCCCCCATGCAATACCGATT
CTGCCCGCAATGCGGCGCGC

Product: L-threonine aldolase

Products: NA

Alternate protein names: Low specificity L-TA [H]

Number of amino acids: Translated: 346; Mature: 345

Protein sequence:

>346_residues
MTKQHFASDNYAGFCPESLKYFLEANGTGHEQAYGDDSWTQKVCDRIRDLFQTDCEVFFVFNGTAANSLALSALCQSYHS
VICHELAHIETDECGGPEFFSNGSKLLTAPGENGKLTPDAIEALVTRRSDIHYPKPKVVSLTQSTEVGTVYTVEEVRAIA
AIAKRRQLRVHMDGARFANAVASLGVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRRLAEDFAYRVKQAGQLASKM
RFISAPWLGLLENNVWLSNARHANAMAQLLQSRIADFPGVRIMFPTESNAVFAELPLPAIEALRAKGWRFYTFIGAGGCR
FMCAWDLQPETVEALAADMHVACAAC

Sequences:

>Translated_346_residues
MTKQHFASDNYAGFCPESLKYFLEANGTGHEQAYGDDSWTQKVCDRIRDLFQTDCEVFFVFNGTAANSLALSALCQSYHS
VICHELAHIETDECGGPEFFSNGSKLLTAPGENGKLTPDAIEALVTRRSDIHYPKPKVVSLTQSTEVGTVYTVEEVRAIA
AIAKRRQLRVHMDGARFANAVASLGVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRRLAEDFAYRVKQAGQLASKM
RFISAPWLGLLENNVWLSNARHANAMAQLLQSRIADFPGVRIMFPTESNAVFAELPLPAIEALRAKGWRFYTFIGAGGCR
FMCAWDLQPETVEALAADMHVACAAC
>Mature_345_residues
TKQHFASDNYAGFCPESLKYFLEANGTGHEQAYGDDSWTQKVCDRIRDLFQTDCEVFFVFNGTAANSLALSALCQSYHSV
ICHELAHIETDECGGPEFFSNGSKLLTAPGENGKLTPDAIEALVTRRSDIHYPKPKVVSLTQSTEVGTVYTVEEVRAIAA
IAKRRQLRVHMDGARFANAVASLGVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRRLAEDFAYRVKQAGQLASKMR
FISAPWLGLLENNVWLSNARHANAMAQLLQSRIADFPGVRIMFPTESNAVFAELPLPAIEALRAKGWRFYTFIGAGGCRF
MCAWDLQPETVEALAADMHVACAAC

Specific function: Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde. Can also act on L-erythro- phenylserine, L-threo-phenylserine, L-beta-3,4- methylenedioxyphenylserine and L-beta-3,4-dihydroxyphenylserine [H]

COG id: COG2008

COG function: function code E; Threonine aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1787095, Length=248, Percent_Identity=28.2258064516129, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193206522, Length=196, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193206524, Length=196, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193206520, Length=196, Percent_Identity=32.1428571428571, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6320789, Length=318, Percent_Identity=25.1572327044025, Blast_Score=80, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.2.5 [H]

Molecular weight: Translated: 38011; Mature: 37879

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQHFASDNYAGFCPESLKYFLEANGTGHEQAYGDDSWTQKVCDRIRDLFQTDCEVFFV
CCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
FNGTAANSLALSALCQSYHSVICHELAHIETDECGGPEFFSNGSKLLTAPGENGKLTPDA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEECCCCCCCCCHHH
IEALVTRRSDIHYPKPKVVSLTQSTEVGTVYTVEEVRAIAAIAKRRQLRVHMDGARFANA
HHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHEEEEECHHHHHHH
VASLGVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRRLAEDFAYRVKQAGQLASKM
HHHCCCCCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFISAPWLGLLENNVWLSNARHANAMAQLLQSRIADFPGVRIMFPTESNAVFAELPLPAI
HHHCCCCHHHHCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHH
EALRAKGWRFYTFIGAGGCRFMCAWDLQPETVEALAADMHVACAAC
HHHHHCCCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHEECC
>Mature Secondary Structure 
TKQHFASDNYAGFCPESLKYFLEANGTGHEQAYGDDSWTQKVCDRIRDLFQTDCEVFFV
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEE
FNGTAANSLALSALCQSYHSVICHELAHIETDECGGPEFFSNGSKLLTAPGENGKLTPDA
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCEEEECCCCCCCCCHHH
IEALVTRRSDIHYPKPKVVSLTQSTEVGTVYTVEEVRAIAAIAKRRQLRVHMDGARFANA
HHHHHHHCCCCCCCCCCEEEEECCCCCCEEEEHHHHHHHHHHHHHHHEEEEECHHHHHHH
VASLGVHPSEITWRAGVDVLCFGGTKNGLPVGEAVVFFDRRLAEDFAYRVKQAGQLASKM
HHHCCCCCCCEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RFISAPWLGLLENNVWLSNARHANAMAQLLQSRIADFPGVRIMFPTESNAVFAELPLPAI
HHHCCCCHHHHCCCEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEECCCHHH
EALRAKGWRFYTFIGAGGCRFMCAWDLQPETVEALAADMHVACAAC
HHHHHCCCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9464392 [H]