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The map label for this gene is fbp [H]

Identifier: 73540530

GI number: 73540530

Start: 896889

End: 897236

Strand: Reverse

Name: fbp [H]

Synonym: Reut_A0827

Alternate gene names: 73540530

Gene position: 897236-896889 (Counterclockwise)

Preceding gene: 73540531

Following gene: 73540528

Centisome position: 23.57

GC content: 66.67

Gene sequence:

>348_bases
ATGCAAACGACCCCGTCTGGCCTGCAGTACGAAGACACCACCGTCGGCTCCGGCGCCGAAGCCGTTGCCGGCAAGCACGT
GACCGTGCACTACACCGGCTGGCTGTACGAAAACGGCCAGGCCGGCCGCAAGTTCGATTCGAGCAAGGATCGCAATGACC
CGTTCGTGTTCCCGCTGGGCGCCGGCCATGTCATCCGCGGCTGGGATGAAGGCGTGCAGGGCATGAAGGTTGGCGGCGTG
CGCCGTCTGGTGATCCCGGCCGACCTGGGCTACGGTGCGCGCGGCGCCGGCGGCGTTATTCCGCCGAACGCCACGCTGCT
GTTCGAAGTGGAATTGCTGGGCGTCTGA

Upstream 100 bases:

>100_bases
TGGATGTACTCCAGCGCGCCGCAGGCTGAGCAGGCCGGCATCGACCTGCCCCGCCCCGATCCCACCGCATTTATTTGCAC
CAACCGGAAGGAATAACACC

Downstream 100 bases:

>100_bases
CGCCAATGACGAAGCGGGCATTGCCCGCTTCGCTTCCGTTTCAGTCTCAGTATTGGCCGAGAAATCGGCTCAGAAGCCGA
TGGCGGCATTGCCGACATCG

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 115; Mature: 115

Protein sequence:

>115_residues
MQTTPSGLQYEDTTVGSGAEAVAGKHVTVHYTGWLYENGQAGRKFDSSKDRNDPFVFPLGAGHVIRGWDEGVQGMKVGGV
RRLVIPADLGYGARGAGGVIPPNATLLFEVELLGV

Sequences:

>Translated_115_residues
MQTTPSGLQYEDTTVGSGAEAVAGKHVTVHYTGWLYENGQAGRKFDSSKDRNDPFVFPLGAGHVIRGWDEGVQGMKVGGV
RRLVIPADLGYGARGAGGVIPPNATLLFEVELLGV
>Mature_115_residues
MQTTPSGLQYEDTTVGSGAEAVAGKHVTVHYTGWLYENGQAGRKFDSSKDRNDPFVFPLGAGHVIRGWDEGVQGMKVGGV
RRLVIPADLGYGARGAGGVIPPNATLLFEVELLGV

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI17149836, Length=110, Percent_Identity=50.9090909090909, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI4503725, Length=110, Percent_Identity=50.9090909090909, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI4758380, Length=110, Percent_Identity=47.2727272727273, Blast_Score=98, Evalue=1e-21,
Organism=Homo sapiens, GI206725530, Length=87, Percent_Identity=57.4712643678161, Blast_Score=96, Evalue=4e-21,
Organism=Homo sapiens, GI17149844, Length=87, Percent_Identity=57.4712643678161, Blast_Score=96, Evalue=4e-21,
Organism=Homo sapiens, GI17149842, Length=87, Percent_Identity=57.4712643678161, Blast_Score=96, Evalue=4e-21,
Organism=Homo sapiens, GI4503729, Length=99, Percent_Identity=50.5050505050505, Blast_Score=96, Evalue=7e-21,
Organism=Homo sapiens, GI224809331, Length=100, Percent_Identity=51, Blast_Score=94, Evalue=3e-20,
Organism=Homo sapiens, GI224809329, Length=100, Percent_Identity=51, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI224809327, Length=100, Percent_Identity=51, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI4758384, Length=100, Percent_Identity=51, Blast_Score=93, Evalue=5e-20,
Organism=Homo sapiens, GI192448443, Length=121, Percent_Identity=40.495867768595, Blast_Score=83, Evalue=4e-17,
Organism=Homo sapiens, GI150010552, Length=103, Percent_Identity=37.8640776699029, Blast_Score=80, Evalue=3e-16,
Organism=Homo sapiens, GI8923659, Length=94, Percent_Identity=42.5531914893617, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI206725547, Length=95, Percent_Identity=42.1052631578947, Blast_Score=72, Evalue=1e-13,
Organism=Homo sapiens, GI33469985, Length=93, Percent_Identity=41.9354838709677, Blast_Score=70, Evalue=3e-13,
Organism=Homo sapiens, GI31317231, Length=95, Percent_Identity=43.1578947368421, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87082390, Length=115, Percent_Identity=46.0869565217391, Blast_Score=87, Evalue=3e-19,
Organism=Escherichia coli, GI1789745, Length=115, Percent_Identity=42.6086956521739, Blast_Score=73, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI71993519, Length=92, Percent_Identity=56.5217391304348, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17540882, Length=92, Percent_Identity=50, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17561782, Length=90, Percent_Identity=54.4444444444444, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17561778, Length=97, Percent_Identity=40.2061855670103, Blast_Score=69, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6320727, Length=96, Percent_Identity=55.2083333333333, Blast_Score=102, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324194, Length=93, Percent_Identity=55.9139784946236, Blast_Score=96, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6323482, Length=109, Percent_Identity=44.954128440367, Blast_Score=85, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6323566, Length=109, Percent_Identity=45.8715596330275, Blast_Score=85, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281363946, Length=92, Percent_Identity=58.695652173913, Blast_Score=114, Evalue=8e-27,
Organism=Drosophila melanogaster, GI17352457, Length=92, Percent_Identity=58.695652173913, Blast_Score=114, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24655568, Length=92, Percent_Identity=58.695652173913, Blast_Score=106, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24647110, Length=114, Percent_Identity=50, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24583150, Length=100, Percent_Identity=47, Blast_Score=87, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21356629, Length=97, Percent_Identity=53.6082474226804, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12142; Mature: 12142

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTTPSGLQYEDTTVGSGAEAVAGKHVTVHYTGWLYENGQAGRKFDSSKDRNDPFVFPLG
CCCCCCCCEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECC
AGHVIRGWDEGVQGMKVGGVRRLVIPADLGYGARGAGGVIPPNATLLFEVELLGV
CCCEEECCCCCCCCEEECCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MQTTPSGLQYEDTTVGSGAEAVAGKHVTVHYTGWLYENGQAGRKFDSSKDRNDPFVFPLG
CCCCCCCCEECCCCCCCCCCCCCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECC
AGHVIRGWDEGVQGMKVGGVRRLVIPADLGYGARGAGGVIPPNATLLFEVELLGV
CCCEEECCCCCCCCEEECCEEEEEEECCCCCCCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]