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The map label for this gene is ribD [H]

Identifier: 73540480

GI number: 73540480

Start: 846449

End: 847564

Strand: Reverse

Name: ribD [H]

Synonym: Reut_A0776

Alternate gene names: 73540480

Gene position: 847564-846449 (Counterclockwise)

Preceding gene: 73540481

Following gene: 73540479

Centisome position: 22.27

GC content: 67.03

Gene sequence:

>1116_bases
ATGTTTTCCGATTCCGACCACGCCGCCATGCAGCAAGCGCTCGCGCTTGCTGCGCGAGGCATGTTCACCACCACCCCCAA
TCCACGCGTCGGTTGCGTGCTGAGCAAGAACGGGCAGATCATCGGCCAGGGCTTCACCCAGCCGGCTGGACAGGATCACG
CCGAAATCCAGGCTTTGAAGGATGCGCAGACGCGCGGCATCGACCCGGCCGGGGCCACTGCCTATGTGACGCTTGAGCCC
TGCAGTCATTTCGGCCGCACGCCCCCCTGTGCCGACGCGCTGGTACGCGCCGGCATCGCGCGCGTGGTGGCGGCAATGGA
AGATCCCAACCCGAGCGTGTCAGGCCGTGGCCTGCAGCGGCTGCGCGACGCCGGCATCGACGTGCGCTGCGGCCTGCTGG
AAAAGGAAGCGCGCGACCTCAACATCGGCTTCGTGTCGCGCATGACGCGCGGCCTGCCGTGGGTGCGGGTCAAGGTCGCG
GCGTCGATGGACGGCGGTACCGCCCTGCACGATGGCACGAGCCAGTGGATCACCGGTCAGGCCGCACGTGACGATGGGCA
CGCCTGGCGCGCGCGCGCCTGCGCCATCCTGACCGGCATCGGCACGGTACGTGACGACAATCCGCAGATGACCGTGCGAG
CCATCCCGACGCCGCGCCAGCCGCAGCGAGTGCTGGTCGATTCGCGCTTAGAAGTGCCGCTTGATGCACGCATCCTGACC
CCGGACTCGGGCGACCTTGCCAAGCCGGTACTGGTGTTCAGTGCCGTGGACGACCGGGAACGCCGCCACGCGCTTGAAGC
CCGCGGCGCCGAGGTCGTGGTGTTGCCGAATCCGCACGGCAAGGTCGAGTTGCGCAAGATGCTGGAGGAACTGGGCCGAC
GCGGCATCAACGAACTGCACGTCGAAGCAGGTTTCAAGCTCAATGGCTCGCTGATCCGCGAGCATTGTGCCGACGAACTG
CTGATCTACCTCGCGCCCAAACTGCTCGGCGATGCACAAGGCATGTTCAACCTGCCGCCGCTGTCCCGGTTGCAGGATGC
CGCCTCCTTCCGCTGGCACGATGTGCGCCAGATCGGCGAGGATCTTCGCCTGATCGCGCGTCGCAGCGACGCCTGA

Upstream 100 bases:

>100_bases
CGCCCGGGCATGACAAGGACTGCGAGGCATCGGGCGAACCTGCCCCGCCCTGACAGCGGCACGCACACCCAACGCCCAGC
GGGCAAGAGTCACCGGCCAA

Downstream 100 bases:

>100_bases
CCCCAACTTATCGACAGCGCGCCAGCCGCGCTGCTTACCAACACCCGAACTTTCGAGAACACATCATGTTTACTGGCATT
GTGGCGGCCGTTGGCCGCAT

Product: 5-amino-6-(5-phosphoribosylamino)uracil reductase / diaminohydroxyphosphoribosylaminopyrimidine deaminase

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MFSDSDHAAMQQALALAARGMFTTTPNPRVGCVLSKNGQIIGQGFTQPAGQDHAEIQALKDAQTRGIDPAGATAYVTLEP
CSHFGRTPPCADALVRAGIARVVAAMEDPNPSVSGRGLQRLRDAGIDVRCGLLEKEARDLNIGFVSRMTRGLPWVRVKVA
ASMDGGTALHDGTSQWITGQAARDDGHAWRARACAILTGIGTVRDDNPQMTVRAIPTPRQPQRVLVDSRLEVPLDARILT
PDSGDLAKPVLVFSAVDDRERRHALEARGAEVVVLPNPHGKVELRKMLEELGRRGINELHVEAGFKLNGSLIREHCADEL
LIYLAPKLLGDAQGMFNLPPLSRLQDAASFRWHDVRQIGEDLRLIARRSDA

Sequences:

>Translated_371_residues
MFSDSDHAAMQQALALAARGMFTTTPNPRVGCVLSKNGQIIGQGFTQPAGQDHAEIQALKDAQTRGIDPAGATAYVTLEP
CSHFGRTPPCADALVRAGIARVVAAMEDPNPSVSGRGLQRLRDAGIDVRCGLLEKEARDLNIGFVSRMTRGLPWVRVKVA
ASMDGGTALHDGTSQWITGQAARDDGHAWRARACAILTGIGTVRDDNPQMTVRAIPTPRQPQRVLVDSRLEVPLDARILT
PDSGDLAKPVLVFSAVDDRERRHALEARGAEVVVLPNPHGKVELRKMLEELGRRGINELHVEAGFKLNGSLIREHCADEL
LIYLAPKLLGDAQGMFNLPPLSRLQDAASFRWHDVRQIGEDLRLIARRSDA
>Mature_371_residues
MFSDSDHAAMQQALALAARGMFTTTPNPRVGCVLSKNGQIIGQGFTQPAGQDHAEIQALKDAQTRGIDPAGATAYVTLEP
CSHFGRTPPCADALVRAGIARVVAAMEDPNPSVSGRGLQRLRDAGIDVRCGLLEKEARDLNIGFVSRMTRGLPWVRVKVA
ASMDGGTALHDGTSQWITGQAARDDGHAWRARACAILTGIGTVRDDNPQMTVRAIPTPRQPQRVLVDSRLEVPLDARILT
PDSGDLAKPVLVFSAVDDRERRHALEARGAEVVVLPNPHGKVELRKMLEELGRRGINELHVEAGFKLNGSLIREHCADEL
LIYLAPKLLGDAQGMFNLPPLSRLQDAASFRWHDVRQIGEDLRLIARRSDA

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=365, Percent_Identity=46.3013698630137, Blast_Score=306, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 40272; Mature: 40272

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSDSDHAAMQQALALAARGMFTTTPNPRVGCVLSKNGQIIGQGFTQPAGQDHAEIQALK
CCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCEEEECCCCCCCCCCHHHHHHHH
DAQTRGIDPAGATAYVTLEPCSHFGRTPPCADALVRAGIARVVAAMEDPNPSVSGRGLQR
HHHHCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LRDAGIDVRCGLLEKEARDLNIGFVSRMTRGLPWVRVKVAASMDGGTALHDGTSQWITGQ
HHHCCCCEEECHHHHCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCCEECCCCCHHEECC
AARDDGHAWRARACAILTGIGTVRDDNPQMTVRAIPTPRQPQRVLVDSRLEVPLDARILT
CCCCCCCHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCEEEC
PDSGDLAKPVLVFSAVDDRERRHALEARGAEVVVLPNPHGKVELRKMLEELGRRGINELH
CCCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
VEAGFKLNGSLIREHCADELLIYLAPKLLGDAQGMFNLPPLSRLQDAASFRWHDVRQIGE
EECCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLRLIARRSDA
HHHHHHHCCCC
>Mature Secondary Structure
MFSDSDHAAMQQALALAARGMFTTTPNPRVGCVLSKNGQIIGQGFTQPAGQDHAEIQALK
CCCCCHHHHHHHHHHHHHCCCEECCCCCCEEEEECCCCEEEECCCCCCCCCCHHHHHHHH
DAQTRGIDPAGATAYVTLEPCSHFGRTPPCADALVRAGIARVVAAMEDPNPSVSGRGLQR
HHHHCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
LRDAGIDVRCGLLEKEARDLNIGFVSRMTRGLPWVRVKVAASMDGGTALHDGTSQWITGQ
HHHCCCCEEECHHHHCCCCCCHHHHHHHHCCCCEEEEEEEEECCCCCEECCCCCHHEECC
AARDDGHAWRARACAILTGIGTVRDDNPQMTVRAIPTPRQPQRVLVDSRLEVPLDARILT
CCCCCCCHHHHHHHHHEECCCCCCCCCCCEEEEECCCCCCCCHHHCCCCCCCCCCCEEEC
PDSGDLAKPVLVFSAVDDRERRHALEARGAEVVVLPNPHGKVELRKMLEELGRRGINELH
CCCCCCCCCEEEEECCCCHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCEEE
VEAGFKLNGSLIREHCADELLIYLAPKLLGDAQGMFNLPPLSRLQDAASFRWHDVRQIGE
EECCCEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
DLRLIARRSDA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]