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The map label for this gene is sucD [H]

Identifier: 73540237

GI number: 73540237

Start: 577506

End: 578387

Strand: Direct

Name: sucD [H]

Synonym: Reut_A0531

Alternate gene names: 73540237

Gene position: 577506-578387 (Clockwise)

Preceding gene: 73540236

Following gene: 73540238

Centisome position: 15.17

GC content: 63.27

Gene sequence:

>882_bases
ATGTCGATTCTGATCAACAAAGACACCAAGGTCATCACCCAGGGCATCACTGGCAAGACCGGCCAGTTCCACACCCGTGG
CTGCCGTGACTACGCCAACGGCAAGAACTGCTTCGTCGCTGGCGTGAACCCGAAGAAGGCCGGCGAAGACTTCGAAGGCA
TTCCCATCTACGCGAGCGTCAAGGACGCCAAGGCCCAGACCGGCGCCACGGTTTCCGTGATCTACGTGCCGCCCGCAGGC
GCCGCTGCCGCCATCTGGGAAGCCGTTGACGCCGACCTGGACCTGGTGGTCTGCATCACCGAAGGCATCCCCGTGCGCGA
CATGATGGAAGTCAAGGACCGCATGCGCCGCGAGAACAAGAAGACCCTGCTGCTGGGACCGAACTGCCCGGGCCTGATCA
CGCCGGACGAAATCAAGATCGGCATCATGCCGGGTCACATCCACCGCAAGGGCCGCATCGGCGTGGTGTCGCGCTCGGGC
ACGCTGACGTACGAAGCCGTGGGCCAGCTGACCGCGCTGGGCCTGGGCCAGTCGTCGGCTGTCGGTATCGGCGGCGACCC
GATCAACGGCCTGAAGCACATCGACGTCATGAAGATGTTCAACGACGATCCGGAAACGGACGCCGTGGTCATGATCGGTG
AAATCGGCGGTCCGGACGAAGCCAACGCGGCTTACTGGATCAAGGACAACATGAAGAAGCCGGTGGTTGGCTTCATCGCT
GGCGTGACCGCGCCTCCGGGCAAGCGCATGGGCCACGCCGGCGCGCTGATCTCGGGTGGTGCCGACACCGCCCAGGCCAA
GCTGGAAATCATGGAAGCCTGCGGTATCACGGTGACCAAGAACCCGTCGGAAATGGCTCGCCTGCTGAAGGCAAAGCTGT
AA

Upstream 100 bases:

>100_bases
GCAAGAAGTAAGCCGGGCGCCGATACCAAACACAAGCGCACTTGGGCAGCGCGCGTGGCTTCGTGCCCGCGCTGCCAAAG
GCCAAGCAAAGGACTAAAGC

Downstream 100 bases:

>100_bases
GCAACACCATCGTGCCTTGCGCGTCACGTGGCGCCCAGGGCCAGTGTTGAACCGCCCCGGACTTCGGCCGGGACGGGTTT
GCCCCCGCCATTGTGCGGGG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKDAKAQTGATVSVIYVPPAG
AAAAIWEAVDADLDLVVCITEGIPVRDMMEVKDRMRRENKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAQAKLEIMEACGITVTKNPSEMARLLKAKL

Sequences:

>Translated_293_residues
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKDAKAQTGATVSVIYVPPAG
AAAAIWEAVDADLDLVVCITEGIPVRDMMEVKDRMRRENKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAQAKLEIMEACGITVTKNPSEMARLLKAKL
>Mature_292_residues
SILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASVKDAKAQTGATVSVIYVPPAGA
AAAIWEAVDADLDLVVCITEGIPVRDMMEVKDRMRRENKKTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGT
LTYEAVGQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIAG
VTAPPGKRMGHAGALISGGADTAQAKLEIMEACGITVTKNPSEMARLLKAKL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=287, Percent_Identity=55.0522648083624, Blast_Score=268, Evalue=4e-72,
Organism=Homo sapiens, GI38569423, Length=252, Percent_Identity=26.984126984127, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI38569421, Length=252, Percent_Identity=26.984126984127, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=53.5836177474403, Blast_Score=308, Evalue=2e-85,
Organism=Escherichia coli, GI1786513, Length=185, Percent_Identity=28.6486486486486, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=55.9027777777778, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17553126, Length=296, Percent_Identity=53.0405405405405, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17557344, Length=242, Percent_Identity=27.6859504132231, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=254, Percent_Identity=25.1968503937008, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=47.2972972972973, Blast_Score=260, Evalue=2e-70,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=50.3424657534247, Blast_Score=282, Evalue=2e-76,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=52.7397260273973, Blast_Score=271, Evalue=3e-73,
Organism=Drosophila melanogaster, GI281363477, Length=250, Percent_Identity=27.6, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363475, Length=250, Percent_Identity=27.6, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281363473, Length=250, Percent_Identity=27.6, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30848; Mature: 30717

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASV
CEEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCHHHCCCCCCCEEEEEEC
KDAKAQTGATVSVIYVPPAGAAAAIWEAVDADLDLVVCITEGIPVRDMMEVKDRMRRENK
CCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSSA
CEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHCEEEECCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEE
GVTAPPGKRMGHAGALISGGADTAQAKLEIMEACGITVTKNPSEMARLLKAKL
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SILINKDTKVITQGITGKTGQFHTRGCRDYANGKNCFVAGVNPKKAGEDFEGIPIYASV
EEEEECCCEEEEECCCCCCCCCCCCCCHHHCCCCEEEEECCCHHHCCCCCCCEEEEEEC
KDAKAQTGATVSVIYVPPAGAAAAIWEAVDADLDLVVCITEGIPVRDMMEVKDRMRRENK
CCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGLITPDEIKIGIMPGHIHRKGRIGVVSRSGTLTYEAVGQLTALGLGQSSA
CEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCEEHHHHHCEEEECCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPETDAVVMIGEIGGPDEANAAYWIKDNMKKPVVGFIA
EECCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCEEEEE
GVTAPPGKRMGHAGALISGGADTAQAKLEIMEACGITVTKNPSEMARLLKAKL
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHCCCEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]