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The map label for this gene is sucC

Identifier: 73540236

GI number: 73540236

Start: 576247

End: 577416

Strand: Direct

Name: sucC

Synonym: Reut_A0530

Alternate gene names: 73540236

Gene position: 576247-577416 (Clockwise)

Preceding gene: 73540235

Following gene: 73540237

Centisome position: 15.14

GC content: 61.71

Gene sequence:

>1170_bases
ATGAATATCCATGAGTACCAAGGCAAGGAAATCCTGCGCAAATACAATGTGCCGGTTCCGCGCGGCATCCCCGCGTTCTC
GGTCGCCGAGGCCCTGAAGGCCGCAGAAGAGCTTGGCGGCCCGGTTTGGGTGGTCAAGGCGCAAATTCATGCGGGTGGCC
GCGGCAAGGGCGGTGGCGTGAAGGTTGCCAAGAGCATCGACGACGTCAAGACCTACGCCACCAACATCCTGGGCATGCAA
CTGGTCACGCACCAGACCGGTCCGGAAGGCAAGAAGGTCAACCGCCTGCTGATCGAAGAAGGCGCCGACATCAAGAAGGA
ACTGTACGTTTCGCTGGTGGTGGACCGCGTTTCGCAAAAGATCGCCCTGATGGCATCGAGCGAAGGCGGCATGGACATCG
AGGAAGTCGCTGCCCACACCCCGGAAAAGATCCACACGCTGATCATCGAGCCGTCGACCGGCCTGACCGACGCTGACGCT
GACGACATCGCCCGCAAGATCGGCGTGCCCGACGCTTCGGTTGCCCAGGCTCGCCAGGCCCTGCAAGGCCTGTACAAGGC
GTTCTACGACACCGACGCTTCGCTGGCCGAAATCAACCCGCTGATCCTGACCGGCGAAGGCAAGGTCATCGCGCTGGACG
CGAAGTTCAACTTCGACTCGAACGCGCTGTTCCGTCATCCGGAAATCGTCGCCTACCGCGACCTGGATGAAGAAGACGCC
AACGAAATCGAAGCTTCGAAGTTCGACCTGGCCTACATCTCGCTGGACGGCAACATCGGCTGCCTGGTGAACGGCGCTGG
CCTGGCCATGGCCACCATGGACACCATCAAGCTGTTCGGCGGCGAGCCGGCCAACTTCCTCGACGTGGGCGGCGGTGCCA
CCACCGAGAAGGTGACCGAAGCCTTCAAGCTGATGCTGAAGAACCCGAACGTGGAAGCCATCCTGGTGAACATCTTCGGC
GGCATCATGCGCTGCGACGTGATCGCCGAAGGCGTGATCTCGGCGTCGAAGGCCGTGAACCTGACGGTACCGCTGGTCGT
GCGCATGAAGGGCACCAACGAAGATCTGGGCAAGAAGATGCTGGCCGATTCGGGCCTGCCGATCATCGCCGCAGACACGA
TGGAAGAAGCCGCCCAGAAGGTTGTGGCCGCTGCCGCCGGCAAGAAGTAA

Upstream 100 bases:

>100_bases
CACTTCCGGCTGATTCTCAGGATCGGCCACGGACGAGAGAGATCGTCTTTTTCAGATTCTTCCCCTTCTACCTTTTACGC
CTACCCGAAAGGAAACACGC

Downstream 100 bases:

>100_bases
GCCGGGCGCCGATACCAAACACAAGCGCACTTGGGCAGCGCGCGTGGCTTCGTGCCCGCGCTGCCAAAGGCCAAGCAAAG
GACTAAAGCATGTCGATTCT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVAEALKAAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIDDVKTYATNILGMQ
LVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQKIALMASSEGGMDIEEVAAHTPEKIHTLIIEPSTGLTDADA
DDIARKIGVPDASVAQARQALQGLYKAFYDTDASLAEINPLILTGEGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDA
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPNVEAILVNIFG
GIMRCDVIAEGVISASKAVNLTVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMEEAAQKVVAAAAGKK

Sequences:

>Translated_389_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVAEALKAAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIDDVKTYATNILGMQ
LVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQKIALMASSEGGMDIEEVAAHTPEKIHTLIIEPSTGLTDADA
DDIARKIGVPDASVAQARQALQGLYKAFYDTDASLAEINPLILTGEGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDA
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPNVEAILVNIFG
GIMRCDVIAEGVISASKAVNLTVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMEEAAQKVVAAAAGKK
>Mature_389_residues
MNIHEYQGKEILRKYNVPVPRGIPAFSVAEALKAAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSIDDVKTYATNILGMQ
LVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQKIALMASSEGGMDIEEVAAHTPEKIHTLIIEPSTGLTDADA
DDIARKIGVPDASVAQARQALQGLYKAFYDTDASLAEINPLILTGEGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDA
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPNVEAILVNIFG
GIMRCDVIAEGVISASKAVNLTVPLVVRMKGTNEDLGKKMLADSGLPIIAADTMEEAAQKVVAAAAGKK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=47.3007712082262, Blast_Score=348, Evalue=4e-96,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.4751958224543, Blast_Score=325, Evalue=4e-89,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=46.7966573816156, Blast_Score=307, Evalue=9e-84,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=52.5773195876289, Blast_Score=404, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=45.29262086514, Blast_Score=340, Evalue=6e-94,
Organism=Caenorhabditis elegans, GI17567829, Length=392, Percent_Identity=46.1734693877551, Blast_Score=332, Evalue=3e-91,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=46.5648854961832, Blast_Score=351, Evalue=1e-97,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=45.9183673469388, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=45.9183673469388, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI21356231, Length=396, Percent_Identity=44.9494949494949, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=46.0559796437659, Blast_Score=325, Evalue=3e-89,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=46.0559796437659, Blast_Score=325, Evalue=3e-89,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SUCC_CUPPJ (Q475M1)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_294756.1
- HSSP:   P53590
- ProteinModelPortal:   Q475M1
- SMR:   Q475M1
- GeneID:   3611250
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A0530
- NMPDR:   fig|264198.3.peg.1042
- HOGENOM:   HBG315432
- OMA:   KKELYVS
- ProtClustDB:   PRK00696
- BioCyc:   REUT264198:REUT_A0530-MONOMER
- HAMAP:   MF_00558
- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- Gene3D:   G3DSA:3.40.50.261
- PANTHER:   PTHR11815
- TIGRFAMs:   TIGR01016

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA; SSF52210 CoA_ligase

EC number: =6.2.1.5

Molecular weight: Translated: 41282; Mature: 41282

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50975 ATP_GRASP; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIHEYQGKEILRKYNVPVPRGIPAFSVAEALKAAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCE
KVAKSIDDVKTYATNILGMQLVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQK
EEHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IALMASSEGGMDIEEVAAHTPEKIHTLIIEPSTGLTDADADDIARKIGVPDASVAQARQA
EEEEECCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
LQGLYKAFYDTDASLAEINPLILTGEGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDA
HHHHHHHHHCCCCCHHHCCCEEEECCCCEEEEEEEECCCCCCEECCCCEEEECCCCCCCH
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
HHHCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPNVEAILVNIFGGIMRCDVIAEGVISASKAVNLTVPLVVRMKGTNEDLGKKM
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCHHHHHHH
LADSGLPIIAADTMEEAAQKVVAAAAGKK
HHCCCCCEEEHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNIHEYQGKEILRKYNVPVPRGIPAFSVAEALKAAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCHHCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCCCCCE
KVAKSIDDVKTYATNILGMQLVTHQTGPEGKKVNRLLIEEGADIKKELYVSLVVDRVSQK
EEHHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
IALMASSEGGMDIEEVAAHTPEKIHTLIIEPSTGLTDADADDIARKIGVPDASVAQARQA
EEEEECCCCCCCHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHH
LQGLYKAFYDTDASLAEINPLILTGEGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDA
HHHHHHHHHCCCCCHHHCCCEEEECCCCEEEEEEEECCCCCCEECCCCEEEECCCCCCCH
NEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
HHHCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPNVEAILVNIFGGIMRCDVIAEGVISASKAVNLTVPLVVRMKGTNEDLGKKM
HHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCHHHHHHH
LADSGLPIIAADTMEEAAQKVVAAAAGKK
HHCCCCCEEEHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA