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The map label for this gene is tal

Identifier: 161611259

GI number: 161611259

Start: 2273981

End: 2274937

Strand: Direct

Name: tal

Synonym: Reut_A2069

Alternate gene names: 161611259

Gene position: 2273981-2274937 (Clockwise)

Preceding gene: 73541755

Following gene: 73541761

Centisome position: 59.74

GC content: 63.74

Gene sequence:

>957_bases
ATGAACCAGCTCGAACAACTCAAGCAGTTCACCACGGTCGTGGCCGATACCGGCGACTTCCAGTTGATGAAGCAGTACAC
GCCGCAGGACGCCACCACCAACCCGTCGCTGATCCTCAAGGCGGTGCAGAAGCCCGAATACCGCGGACTTCTGGAACAGG
CCGTGCGCGACTACCACAACGAAGGCGGTGTCGACGCCGTGATGGACGGCGTGCTGATCGCGTTCGGCTGCGAGATCCTC
GCCATCGTGCCCGGACGTGTGTCGACGGAGGTCGATGCGCGGCTGTCGTTCGATACCGAAGCGACGGTCGAAAAGGCCCG
CCACCTGATCCGCCTGTACGAACAGCGCGGCGTGGCGCGCGAGCGCGTGCTGATCAAGATTGCATCGACGTGGGAAGGCA
TCCGCGCCGCCGAGATCCTGCAGCGCGAAGGCATCCGCTGCAACATGACGCTGCTGTTCTCGCTGGTGCAGGCAGTCGCG
TGCGCCGAGGCCGGCGCGCAACTGATCTCGCCGTTCGTCGGTCGCATCCTCGACTGGTACAAGAAGCAGGCCGGCGACCA
GTGGGACGCTGCCGCCAATGCGGGCGACAACGATCCGGGCGTGCGCTCCGTGCGCCAGATCTACGACTACTACAAGAAAT
TCGGCTACAACACCGAAGTGATGGGGGCCAGCTTCCGCAGCACTGCACAGATCGTCGCGCTGGCCGGCAGCGACCTGCTC
ACGATCAGCCCGGACCTGCTCGAGCAACTGGCACGCACCGAAGGCACGGTGGAGCGCAAGCTGTCGGTCGATCTCGCACA
GGCAGGCAATATTGCCCGCATCCCGGCCGATGAGCCAGCCTTCCGCTGGCAGCTCAACGAAGACGCCATGGCCACCGAGA
AACTCGCTGAAGGCATCCGTCTGTTTGCTGCGGACGCAATCAAGCTGGAAAAGCTGGTTGCGGAAATCGCCGGCTAA

Upstream 100 bases:

>100_bases
TTGCGATGGCAAGGCTGCCCGCGACGGTACAATGCCTCAACGGCGCCGCGAGTCGGCCGCCTTCCCGCCTCCCCATGACG
ACTGCAACGACTTACCGATC

Downstream 100 bases:

>100_bases
GGCGCCGACCGAGGCGGCCGCTCAGTCCATCTCCGTATCGGAGCCGGACTGCGGCCATAGCAGCGGCAGGCTTGCACCTG
CTGCTGCCTGCAGTACCACA

Product: transaldolase B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MNQLEQLKQFTTVVADTGDFQLMKQYTPQDATTNPSLILKAVQKPEYRGLLEQAVRDYHNEGGVDAVMDGVLIAFGCEIL
AIVPGRVSTEVDARLSFDTEATVEKARHLIRLYEQRGVARERVLIKIASTWEGIRAAEILQREGIRCNMTLLFSLVQAVA
CAEAGAQLISPFVGRILDWYKKQAGDQWDAAANAGDNDPGVRSVRQIYDYYKKFGYNTEVMGASFRSTAQIVALAGSDLL
TISPDLLEQLARTEGTVERKLSVDLAQAGNIARIPADEPAFRWQLNEDAMATEKLAEGIRLFAADAIKLEKLVAEIAG

Sequences:

>Translated_318_residues
MNQLEQLKQFTTVVADTGDFQLMKQYTPQDATTNPSLILKAVQKPEYRGLLEQAVRDYHNEGGVDAVMDGVLIAFGCEIL
AIVPGRVSTEVDARLSFDTEATVEKARHLIRLYEQRGVARERVLIKIASTWEGIRAAEILQREGIRCNMTLLFSLVQAVA
CAEAGAQLISPFVGRILDWYKKQAGDQWDAAANAGDNDPGVRSVRQIYDYYKKFGYNTEVMGASFRSTAQIVALAGSDLL
TISPDLLEQLARTEGTVERKLSVDLAQAGNIARIPADEPAFRWQLNEDAMATEKLAEGIRLFAADAIKLEKLVAEIAG
>Mature_318_residues
MNQLEQLKQFTTVVADTGDFQLMKQYTPQDATTNPSLILKAVQKPEYRGLLEQAVRDYHNEGGVDAVMDGVLIAFGCEIL
AIVPGRVSTEVDARLSFDTEATVEKARHLIRLYEQRGVARERVLIKIASTWEGIRAAEILQREGIRCNMTLLFSLVQAVA
CAEAGAQLISPFVGRILDWYKKQAGDQWDAAANAGDNDPGVRSVRQIYDYYKKFGYNTEVMGASFRSTAQIVALAGSDLL
TISPDLLEQLARTEGTVERKLSVDLAQAGNIARIPADEPAFRWQLNEDAMATEKLAEGIRLFAADAIKLEKLVAEIAG

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=318, Percent_Identity=56.6037735849057, Blast_Score=356, Evalue=2e-98,
Organism=Escherichia coli, GI1788807, Length=320, Percent_Identity=57.8125, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI1786189, Length=321, Percent_Identity=57.3208722741433, Blast_Score=347, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI25153750, Length=319, Percent_Identity=55.7993730407524, Blast_Score=344, Evalue=3e-95,
Organism=Caenorhabditis elegans, GI25153752, Length=165, Percent_Identity=57.5757575757576, Blast_Score=184, Evalue=7e-47,
Organism=Caenorhabditis elegans, GI17570473, Length=93, Percent_Identity=56.989247311828, Blast_Score=97, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6321480, Length=323, Percent_Identity=54.4891640866873, Blast_Score=335, Evalue=5e-93,
Organism=Saccharomyces cerevisiae, GI6323386, Length=322, Percent_Identity=59.0062111801242, Blast_Score=328, Evalue=7e-91,
Organism=Drosophila melanogaster, GI45549185, Length=319, Percent_Identity=57.9937304075235, Blast_Score=357, Evalue=5e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_CUPPJ (Q46ZK0)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_296277.2
- ProteinModelPortal:   Q46ZK0
- SMR:   Q46ZK0
- GeneID:   3611736
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A2069
- NMPDR:   fig|264198.3.peg.2755
- HOGENOM:   HBG286747
- ProtClustDB:   PRK05269
- BioCyc:   REUT264198:REUT_A2069-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00492
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004730
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- PANTHER:   PTHR10683:SF3
- TIGRFAMs:   TIGR00874

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 35053; Mature: 35053

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 126-126

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQLEQLKQFTTVVADTGDFQLMKQYTPQDATTNPSLILKAVQKPEYRGLLEQAVRDYHN
CCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
EGGVDAVMDGVLIAFGCEILAIVPGRVSTEVDARLSFDTEATVEKARHLIRLYEQRGVAR
CCCHHHHHHHHHHHHCCHHEEECCCCCCCCHHCEECCCHHHHHHHHHHHHHHHHHHCCHH
ERVLIKIASTWEGIRAAEILQREGIRCNMTLLFSLVQAVACAEAGAQLISPFVGRILDWY
HHHHHEEHHHHCCHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQAGDQWDAAANAGDNDPGVRSVRQIYDYYKKFGYNTEVMGASFRSTAQIVALAGSDLL
HHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHEEEEECCCCE
TISPDLLEQLARTEGTVERKLSVDLAQAGNIARIPADEPAFRWQLNEDAMATEKLAEGIR
EECHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCHHHHHHHHHHHHH
LFAADAIKLEKLVAEIAG
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNQLEQLKQFTTVVADTGDFQLMKQYTPQDATTNPSLILKAVQKPEYRGLLEQAVRDYHN
CCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCC
EGGVDAVMDGVLIAFGCEILAIVPGRVSTEVDARLSFDTEATVEKARHLIRLYEQRGVAR
CCCHHHHHHHHHHHHCCHHEEECCCCCCCCHHCEECCCHHHHHHHHHHHHHHHHHHCCHH
ERVLIKIASTWEGIRAAEILQREGIRCNMTLLFSLVQAVACAEAGAQLISPFVGRILDWY
HHHHHEEHHHHCCHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KKQAGDQWDAAANAGDNDPGVRSVRQIYDYYKKFGYNTEVMGASFRSTAQIVALAGSDLL
HHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCHHCCCCHHHHHHEEEEECCCCE
TISPDLLEQLARTEGTVERKLSVDLAQAGNIARIPADEPAFRWQLNEDAMATEKLAEGIR
EECHHHHHHHHHCCCHHHHHHHHHHHHCCCEEECCCCCCCEEEECCCHHHHHHHHHHHHH
LFAADAIKLEKLVAEIAG
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA