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The map label for this gene is yeaD [H]

Identifier: 71908346

GI number: 71908346

Start: 2928052

End: 2928897

Strand: Reverse

Name: yeaD [H]

Synonym: Daro_2733

Alternate gene names: 71908346

Gene position: 2928897-2928052 (Counterclockwise)

Preceding gene: 71908347

Following gene: 71908345

Centisome position: 65.07

GC content: 60.99

Gene sequence:

>846_bases
ATGAAACCCTCCATTGAAGATATCGAATTTCACGGCATCGAAGCCCTGCGCCTGAACGGACCACGCGGGGTCAGTGCCAT
CGTCAGCAAACAGGGGGCGCAGTTGCTGTCCTGGGTGAGTGCGGATGGCCGCGAACGCCTGTTCCTTTCCGATAAGGCGG
TGTTCGACGGCAGCGTCGCCATTCGCGGCGGGGTTCCTGTCTGTTTCCCGCAATTTTCCAGTCTGGGCGACCTGCCCAAG
CATGGTTTTTTGCGGACTCGCTCGTGGTCAGTCAGCACCCGGCGTACCGGCGACGATTACGCGCTGGTGACGCTCGAATG
CGCTGACGATGAATCGACGCGCAGCCTCTGGCCGCATTCCTTTCTGGCGGAATTGACGGTCATGCTTGAGGCGGATCGGA
TTGATCTGGAACTGGCGGTGACCAATACCGGCAGTGCACCATTCGACTTTACCGGTGCGTTGCACTCCTACTTGCGCGTT
GTGCAAGTCGAGGATGTCACGCTCGAAGGGTTGCACGGTCATGATTACCAGGATGCCGTGGAAGGCGATCGGGTCGTTCG
CGAAACCGGCACCGAGTTGATCATCGAAAAGGAAGTGGATCGCGCCTATCGCGACGTGCGCCGGCCGCAGCATCTGAAGG
CCGGTAATCTGAGTCTCGGTATCCAGGCCCAGGGCTTTCCGGATGTCGTGGTCTGGAACCCATGGGCGGATCGTTGTGCC
GAATTGAAGGACATGCCGACCGATGGCTGGCGCCATATGCTCTGCGTCGAGGCGGCGGCGACCCGTCCGGTCAGCCTGCC
GGCGGGCGAGGAGTGGTATGGGCGGCAGACCTTGGTGGTGGTCTGA

Upstream 100 bases:

>100_bases
GATACAGGCGATAACCGCTGCTTCGGCAGCGTGACCCTGCTCGGGCATGAAGTCGAAATTCTGCATGTCCGCCCCCACCT
TTACGTGATATCAAATTCCC

Downstream 100 bases:

>100_bases
TTGATTGACGCAGACGAGCTTCCGGCAGCACGTGCTTTTGCGGGAGCATCATCCGATTTCCTTCCCGACCGGCCGATGAG
TTCAAGCACGCTGGATGGGG

Product: aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKPSIEDIEFHGIEALRLNGPRGVSAIVSKQGAQLLSWVSADGRERLFLSDKAVFDGSVAIRGGVPVCFPQFSSLGDLPK
HGFLRTRSWSVSTRRTGDDYALVTLECADDESTRSLWPHSFLAELTVMLEADRIDLELAVTNTGSAPFDFTGALHSYLRV
VQVEDVTLEGLHGHDYQDAVEGDRVVRETGTELIIEKEVDRAYRDVRRPQHLKAGNLSLGIQAQGFPDVVVWNPWADRCA
ELKDMPTDGWRHMLCVEAAATRPVSLPAGEEWYGRQTLVVV

Sequences:

>Translated_281_residues
MKPSIEDIEFHGIEALRLNGPRGVSAIVSKQGAQLLSWVSADGRERLFLSDKAVFDGSVAIRGGVPVCFPQFSSLGDLPK
HGFLRTRSWSVSTRRTGDDYALVTLECADDESTRSLWPHSFLAELTVMLEADRIDLELAVTNTGSAPFDFTGALHSYLRV
VQVEDVTLEGLHGHDYQDAVEGDRVVRETGTELIIEKEVDRAYRDVRRPQHLKAGNLSLGIQAQGFPDVVVWNPWADRCA
ELKDMPTDGWRHMLCVEAAATRPVSLPAGEEWYGRQTLVVV
>Mature_281_residues
MKPSIEDIEFHGIEALRLNGPRGVSAIVSKQGAQLLSWVSADGRERLFLSDKAVFDGSVAIRGGVPVCFPQFSSLGDLPK
HGFLRTRSWSVSTRRTGDDYALVTLECADDESTRSLWPHSFLAELTVMLEADRIDLELAVTNTGSAPFDFTGALHSYLRV
VQVEDVTLEGLHGHDYQDAVEGDRVVRETGTELIIEKEVDRAYRDVRRPQHLKAGNLSLGIQAQGFPDVVVWNPWADRCA
ELKDMPTDGWRHMLCVEAAATRPVSLPAGEEWYGRQTLVVV

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=245, Percent_Identity=35.5102040816327, Blast_Score=122, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6323746, Length=270, Percent_Identity=30.7407407407407, Blast_Score=120, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19921284, Length=269, Percent_Identity=32.3420074349442, Blast_Score=144, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28574481, Length=179, Percent_Identity=30.7262569832402, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 31157; Mature: 31157

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSIEDIEFHGIEALRLNGPRGVSAIVSKQGAQLLSWVSADGRERLFLSDKAVFDGSVA
CCCCCCCEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEECCCEE
IRGGVPVCFPQFSSLGDLPKHGFLRTRSWSVSTRRTGDDYALVTLECADDESTRSLWPHS
EECCCCEECCCHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCCHHCCCHH
FLAELTVMLEADRIDLELAVTNTGSAPFDFTGALHSYLRVVQVEDVTLEGLHGHDYQDAV
HHHHEEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHEEEEEECEEEECCCCCCCHHHH
EGDRVVRETGTELIIEKEVDRAYRDVRRPQHLKAGNLSLGIQAQGFPDVVVWNPWADRCA
HHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEECCHHHHHH
ELKDMPTDGWRHMLCVEAAATRPVSLPAGEEWYGRQTLVVV
HHHCCCCCCHHEEEEEEHHCCCCCCCCCCCCCCCCEEEEEC
>Mature Secondary Structure
MKPSIEDIEFHGIEALRLNGPRGVSAIVSKQGAQLLSWVSADGRERLFLSDKAVFDGSVA
CCCCCCCEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEECCCEE
IRGGVPVCFPQFSSLGDLPKHGFLRTRSWSVSTRRTGDDYALVTLECADDESTRSLWPHS
EECCCCEECCCHHCCCCCCCCCCEEECCCCCCCCCCCCCEEEEEEEECCCCCCHHCCCHH
FLAELTVMLEADRIDLELAVTNTGSAPFDFTGALHSYLRVVQVEDVTLEGLHGHDYQDAV
HHHHEEEEEECCCEEEEEEEECCCCCCCCHHHHHHHHHEEEEEECEEEECCCCCCCHHHH
EGDRVVRETGTELIIEKEVDRAYRDVRRPQHLKAGNLSLGIQAQGFPDVVVWNPWADRCA
HHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEECCHHHHHH
ELKDMPTDGWRHMLCVEAAATRPVSLPAGEEWYGRQTLVVV
HHHCCCCCCHHEEEEEEHHCCCCCCCCCCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]