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The map label for this gene is clpB [H]

Identifier: 71908340

GI number: 71908340

Start: 2920219

End: 2922810

Strand: Reverse

Name: clpB [H]

Synonym: Daro_2727

Alternate gene names: 71908340

Gene position: 2922810-2920219 (Counterclockwise)

Preceding gene: 71908342

Following gene: 71908336

Centisome position: 64.94

GC content: 60.34

Gene sequence:

>2592_bases
ATGCGCCTTGATAAGTTTACGACCAAATTTCAGCAGTCTTTAGCCGATGCCCAAAGTCTGGCCATTGGCGGCGACCAGCA
ATTCATCGAACCGCAGCACCTGCTGCTCGCCCTGATCAATCAGGATGACGGCGGAACGACCTCGTTGCTGTCGCGCGCCG
GTGTTAACGTACCCGGCCTGAAGCGCGATCTTGAACAGGCGCTGACCCGTTTGCCACAAGTCCAGGGCCACGGCGGTGAT
GTCTCCATTGGCCGCGACCTGAACAACCTGCTCAATCTGACCGACAAGGAAGCTCAGAAGCGTGGCGACCAGTTCATCGC
CAGCGAGATGTTCCTGCTCGCCTTGTGCGACGACAAGAACGAAACCGGCCGCATTGCCAAGCAGCATGGCTTTTCCCGCA
AGTCCATCGAAGCGGCGATCATGGCCGTGCGTGGTGGACAGGGGGTCGATTCTCAGGAAGCTGAAGGTCAGCGCGAATCG
CTGAAGAAATACTGCATCGATCTGACCGAACGCGCCGCTCAGGGGAAACTCGACCCGGTCATCGGTCGCGACGATGAAAT
CCGCCGCGCTATCCAGATCCTGCAGCGCCGCACCAAGAACAACCCGGTGCTGATCGGCGAGCCGGGTGTTGGCAAGACGG
CCATCGTCGAGGGGTTGGCCCAGCGTATCGTCAATGAAGAAGTGCCGGAAACCCTGAAGGGCAAGAAGGTGCTGGTCCTC
GATATGGCCGGCCTGCTGGCCGGGGCCAAGTATCGCGGTGAATTCGAGGAGCGCCTGAAAGCCGTGCTCAAGGAAGTGGC
GCAGGACGAAGGTCGCATCATCCTGTTCATCGACGAACTGCACACCATGGTCGGCGCCGGTAAGGCTGAAGGTGCCATCG
ACGCGGGCAACATGCTGAAACCAGCATTGGCGCGTGGCGAACTGCACTGCATCGGTGCGACGACACTGAACGAATACCGC
AAATATATCGAGAAGGACGCCGCGCTGGAGCGTCGTTTCCAGAAGGTGCTGGTCGAGGAGCCGAGCGTCGAATCGACCAT
CGCCATCCTGCGCGGCCTGCAGGAAAAGTACGAGCTGCACCACGGCGTCGATATCACCGACCCGGCCATCGTTGCTGCCG
CCGAGTTGTCGCACCGCTACATCACCGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGACGAAGCTGCGGCCCGC
ATCAAGATGGAAATCGATTCCAAGCCGGAAGTGATGGACAAGCTGGATCGTCGCATCATCCAGCTCAAGATCGAGCGCGA
GGCGGTCAAGAAAGAAAAGGACGAGGCTTCCAAGAAGCGATTTGGCCTGATCGAAGAGGAAATCGCCAAGCTGACCAAGG
AATACTCCGACCTGGAAGAGGTTTGGAAAGCCGAGAAGTCCGCTGTGCTTGGTTCTGCCCAGATCAAGGAAGAAATCGAT
CATCTGAAGGCTGACATCGCCCGCCTGCAGCGCGAAGGCAAACTAGGCGAAGTGGCCGAACTGCAATACGGCAAGCTGCC
ACAGCTGGAAGCGCAGTTGAAGGCTGCCGAGAAAGCTGGCGAGGGCGAAGGTCGAAAGAACAAGCTGCTGCGCACGCAGG
TTGGCGCCGAGGAAATCGCCGAGGTGGTCTCCCGTGCCACGGGTATTCCGGTCAGCAAGATGATGCAGGGCGAGCGCGAG
AAGCTGCTCAACATGGAAGACCGGCTGCACAAGCGCGTCGTCGGTCAGGATGAAGCGGTGCGCCTGGTGGGCGACGCCAT
TCGTCGTTCGCGGGCCGGTCTGTCCGATCCCAACCGTCCGTACGGATCCTTCCTGTTCCTTGGCCCGACCGGTGTCGGCA
AAACCGAGCTGTGCAAGGCGCTGGCCGAGTTCATGTTCGACGCCGAAGACCACCTGATCCGCATCGACATGAGCGAGTTC
ATGGAGAAGCACTCGGTCGCCCGCCTGATCGGCGCGCCGCCGGGCTACGTTGGCTACGAAGAGGGCGGTTACCTGACCGA
AGCCGTGCGTCGCAAGCCGTACAGCGTGATCCTGCTCGATGAGGTCGAGAAGGCCCACCCGGATGTCTTCAACGTGCTGC
TGCAGGTGCTCGACGATGGCCGGATGACCGATGGCCAGGGGCGCACGGTGGACTTCAAGAACACCGTGATCGTGATGACC
TCCAACCTCGGCAGCCAGATGATCCAGCAGATGTCAGGCGACGACTACGGCGTGATCAAGGTCGCGGTGATGGCCGAGGT
CAAGAACTACTTCCGGCCGGAGTTCATCAACCGGATTGACGAAGTGGTGGTCTTCCATGCGCTGGACGAAAAGCATATCG
CCGGCATCGCGAAGATTCAGCTAGGCTATCTCGAAAAGCGCCTGGCCCAGCTCGAAATGGGCATCGTGGTTGAAGACAGC
GCACTGGCCGAACTGGCGCAGGCCGGGTTCGACCCGGTGTTCGGGGCACGTCCGCTCAAGCGGGCGATCCAGCAGCAGAT
CGAGAATCCGCTGGCCAAGGCCATCCTGGAAGGGAAGTTTGGCGCCAAGGATACGATCAATGTTAGCTGCGATCCTGCCA
CCGGCGGCATCATGCGCTTCAGCAAGGCCTGA

Upstream 100 bases:

>100_bases
CAAGGCGATAGGATCTTCGATCAAGTTATTGGTGTGCTTGAAATCTACCAATGCGTCCTCATCTAGCAGCCTATAGAAAA
TCCGACTTTGGAGATCATCG

Downstream 100 bases:

>100_bases
TCGGCGCGGGGCTGCAAACAAAAAGGGCGATGCCGCGGCATCGCCCTTTTTACATTTGGCGCTGCGAGATCAGCAGCGTC
CCTTCTTGGCCTGTCCTGGC

Product: AAA ATPase, central region:Clp, N terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 863; Mature: 863

Protein sequence:

>863_residues
MRLDKFTTKFQQSLADAQSLAIGGDQQFIEPQHLLLALINQDDGGTTSLLSRAGVNVPGLKRDLEQALTRLPQVQGHGGD
VSIGRDLNNLLNLTDKEAQKRGDQFIASEMFLLALCDDKNETGRIAKQHGFSRKSIEAAIMAVRGGQGVDSQEAEGQRES
LKKYCIDLTERAAQGKLDPVIGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNEEVPETLKGKKVLVL
DMAGLLAGAKYRGEFEERLKAVLKEVAQDEGRIILFIDELHTMVGAGKAEGAIDAGNMLKPALARGELHCIGATTLNEYR
KYIEKDAALERRFQKVLVEEPSVESTIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAR
IKMEIDSKPEVMDKLDRRIIQLKIEREAVKKEKDEASKKRFGLIEEEIAKLTKEYSDLEEVWKAEKSAVLGSAQIKEEID
HLKADIARLQREGKLGEVAELQYGKLPQLEAQLKAAEKAGEGEGRKNKLLRTQVGAEEIAEVVSRATGIPVSKMMQGERE
KLLNMEDRLHKRVVGQDEAVRLVGDAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTELCKALAEFMFDAEDHLIRIDMSEF
MEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMT
SNLGSQMIQQMSGDDYGVIKVAVMAEVKNYFRPEFINRIDEVVVFHALDEKHIAGIAKIQLGYLEKRLAQLEMGIVVEDS
ALAELAQAGFDPVFGARPLKRAIQQQIENPLAKAILEGKFGAKDTINVSCDPATGGIMRFSKA

Sequences:

>Translated_863_residues
MRLDKFTTKFQQSLADAQSLAIGGDQQFIEPQHLLLALINQDDGGTTSLLSRAGVNVPGLKRDLEQALTRLPQVQGHGGD
VSIGRDLNNLLNLTDKEAQKRGDQFIASEMFLLALCDDKNETGRIAKQHGFSRKSIEAAIMAVRGGQGVDSQEAEGQRES
LKKYCIDLTERAAQGKLDPVIGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNEEVPETLKGKKVLVL
DMAGLLAGAKYRGEFEERLKAVLKEVAQDEGRIILFIDELHTMVGAGKAEGAIDAGNMLKPALARGELHCIGATTLNEYR
KYIEKDAALERRFQKVLVEEPSVESTIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAR
IKMEIDSKPEVMDKLDRRIIQLKIEREAVKKEKDEASKKRFGLIEEEIAKLTKEYSDLEEVWKAEKSAVLGSAQIKEEID
HLKADIARLQREGKLGEVAELQYGKLPQLEAQLKAAEKAGEGEGRKNKLLRTQVGAEEIAEVVSRATGIPVSKMMQGERE
KLLNMEDRLHKRVVGQDEAVRLVGDAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTELCKALAEFMFDAEDHLIRIDMSEF
MEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMT
SNLGSQMIQQMSGDDYGVIKVAVMAEVKNYFRPEFINRIDEVVVFHALDEKHIAGIAKIQLGYLEKRLAQLEMGIVVEDS
ALAELAQAGFDPVFGARPLKRAIQQQIENPLAKAILEGKFGAKDTINVSCDPATGGIMRFSKA
>Mature_863_residues
MRLDKFTTKFQQSLADAQSLAIGGDQQFIEPQHLLLALINQDDGGTTSLLSRAGVNVPGLKRDLEQALTRLPQVQGHGGD
VSIGRDLNNLLNLTDKEAQKRGDQFIASEMFLLALCDDKNETGRIAKQHGFSRKSIEAAIMAVRGGQGVDSQEAEGQRES
LKKYCIDLTERAAQGKLDPVIGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNEEVPETLKGKKVLVL
DMAGLLAGAKYRGEFEERLKAVLKEVAQDEGRIILFIDELHTMVGAGKAEGAIDAGNMLKPALARGELHCIGATTLNEYR
KYIEKDAALERRFQKVLVEEPSVESTIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAAR
IKMEIDSKPEVMDKLDRRIIQLKIEREAVKKEKDEASKKRFGLIEEEIAKLTKEYSDLEEVWKAEKSAVLGSAQIKEEID
HLKADIARLQREGKLGEVAELQYGKLPQLEAQLKAAEKAGEGEGRKNKLLRTQVGAEEIAEVVSRATGIPVSKMMQGERE
KLLNMEDRLHKRVVGQDEAVRLVGDAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTELCKALAEFMFDAEDHLIRIDMSEF
MEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMT
SNLGSQMIQQMSGDDYGVIKVAVMAEVKNYFRPEFINRIDEVVVFHALDEKHIAGIAKIQLGYLEKRLAQLEMGIVVEDS
ALAELAQAGFDPVFGARPLKRAIQQQIENPLAKAILEGKFGAKDTINVSCDPATGGIMRFSKA

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=300, Percent_Identity=38.6666666666667, Blast_Score=214, Evalue=2e-55,
Organism=Escherichia coli, GI1788943, Length=841, Percent_Identity=68.7277051129608, Blast_Score=1171, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=436, Percent_Identity=38.5321100917431, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320464, Length=699, Percent_Identity=52.0743919885551, Blast_Score=729, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=858, Percent_Identity=43.4731934731935, Blast_Score=680, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95484; Mature: 95484

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDKFTTKFQQSLADAQSLAIGGDQQFIEPQHLLLALINQDDGGTTSLLSRAGVNVPGL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCH
KRDLEQALTRLPQVQGHGGDVSIGRDLNNLLNLTDKEAQKRGDQFIASEMFLLALCDDKN
HHHHHHHHHHCCCCCCCCCCEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCC
ETGRIAKQHGFSRKSIEAAIMAVRGGQGVDSQEAEGQRESLKKYCIDLTERAAQGKLDPV
CCCCHHHHCCCCHHHHHHHHHEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNEEVPETLKGKKVLVL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEE
DMAGLLAGAKYRGEFEERLKAVLKEVAQDEGRIILFIDELHTMVGAGKAEGAIDAGNMLK
EHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHH
PALARGELHCIGATTLNEYRKYIEKDAALERRFQKVLVEEPSVESTIAILRGLQEKYELH
HHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAARIKMEIDSKPEVMDKLDRRII
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
QLKIEREAVKKEKDEASKKRFGLIEEEIAKLTKEYSDLEEVWKAEKSAVLGSAQIKEEID
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLKADIARLQREGKLGEVAELQYGKLPQLEAQLKAAEKAGEGEGRKNKLLRTQVGAEEIA
HHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHH
EVVSRATGIPVSKMMQGEREKLLNMEDRLHKRVVGQDEAVRLVGDAIRRSRAGLSDPNRP
HHHHHHCCCCHHHHHCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
YGSFLFLGPTGVGKTELCKALAEFMFDAEDHLIRIDMSEFMEKHSVARLIGAPPGYVGYE
CCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
EGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMT
CCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEE
SNLGSQMIQQMSGDDYGVIKVAVMAEVKNYFRPEFINRIDEVVVFHALDEKHIAGIAKIQ
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LGYLEKRLAQLEMGIVVEDSALAELAQAGFDPVFGARPLKRAIQQQIENPLAKAILEGKF
HHHHHHHHHHHHHCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GAKDTINVSCDPATGGIMRFSKA
CCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRLDKFTTKFQQSLADAQSLAIGGDQQFIEPQHLLLALINQDDGGTTSLLSRAGVNVPGL
CCCHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCH
KRDLEQALTRLPQVQGHGGDVSIGRDLNNLLNLTDKEAQKRGDQFIASEMFLLALCDDKN
HHHHHHHHHHCCCCCCCCCCEECCCCHHHHHCCCHHHHHHHHHHHHHHHHHEEEEECCCC
ETGRIAKQHGFSRKSIEAAIMAVRGGQGVDSQEAEGQRESLKKYCIDLTERAAQGKLDPV
CCCCHHHHCCCCHHHHHHHHHEEECCCCCCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRAIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNEEVPETLKGKKVLVL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCHHHCCCEEEEE
DMAGLLAGAKYRGEFEERLKAVLKEVAQDEGRIILFIDELHTMVGAGKAEGAIDAGNMLK
EHHHHHHCCHHCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCCHHH
PALARGELHCIGATTLNEYRKYIEKDAALERRFQKVLVEEPSVESTIAILRGLQEKYELH
HHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAAARIKMEIDSKPEVMDKLDRRII
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHH
QLKIEREAVKKEKDEASKKRFGLIEEEIAKLTKEYSDLEEVWKAEKSAVLGSAQIKEEID
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLKADIARLQREGKLGEVAELQYGKLPQLEAQLKAAEKAGEGEGRKNKLLRTQVGAEEIA
HHHHHHHHHHHCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHH
EVVSRATGIPVSKMMQGEREKLLNMEDRLHKRVVGQDEAVRLVGDAIRRSRAGLSDPNRP
HHHHHHCCCCHHHHHCCHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCC
YGSFLFLGPTGVGKTELCKALAEFMFDAEDHLIRIDMSEFMEKHSVARLIGAPPGYVGYE
CCCEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCC
EGGYLTEAVRRKPYSVILLDEVEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVIVMT
CCCHHHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEEEEE
SNLGSQMIQQMSGDDYGVIKVAVMAEVKNYFRPEFINRIDEVVVFHALDEKHIAGIAKIQ
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LGYLEKRLAQLEMGIVVEDSALAELAQAGFDPVFGARPLKRAIQQQIENPLAKAILEGKF
HHHHHHHHHHHHHCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GAKDTINVSCDPATGGIMRFSKA
CCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]