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The map label for this gene is 71908132

Identifier: 71908132

GI number: 71908132

Start: 2713133

End: 2714098

Strand: Reverse

Name: 71908132

Synonym: Daro_2516

Alternate gene names: NA

Gene position: 2714098-2713133 (Counterclockwise)

Preceding gene: 71908137

Following gene: 71908131

Centisome position: 60.3

GC content: 58.39

Gene sequence:

>966_bases
ATGCGCCGTTTTGTGCGCTGCTTCGCAGAGAGAGAACAAGTGACGACCACTGCCTTCATTACCCATCGCGACTGCCAGTT
GCACGATATGGGGTCGCATCATCCTGAATGCCCGCAGCGTTTGACCGCCATCAACGATCACCTGATCGCTCAAGGGATCG
ACGCTTACTTTACCTACTACGACGCACCGCTGGCCACTTTCGAGCAATTGTTGCGTGTTCACCCGGCTTCGCATCTTGAG
CGCATCAAGCGTGCCTCACCGGAGCTGGGGGTGGTGCACCTGGATCCGGATACCGCGATGAACCCGCATACTTGGCAGGC
TGCGCTACGCGCCGCTGGTGCAGGCTGCATGGCGGTTGATCTGGTGCTGAACAAGGAGGTCGAGAATGCTTTCTGTGCTG
TTCGCCCGCCTGGTCACCATTGCGAGAAAGCCACGCCGATGGGCTTCTGCTTCTTCAACAACATTGGCGTTGCCGCGCGT
CACGCCTTGAAGGTACACGGCCTGGAGCGCGTTGCCATCATCGACTTTGACGTGCACCACGGTAACGGTACTGAAGACTG
CTTTGCCGGCGACGAGCAGGTGCTGATGTGCAGCATCTTCCAGCATCCGTTTTATCCGTATAGTGGCGCCGACAAGCCAG
CTGCCAACATGTGCAATGTGCCACTCGCCGCAGGCTGTGGCGGAGAAGAGTTCCGCGATGCAGTGATGCAGGTATGGACG
CCGCGCCTCAAGGAGTTCAAGCCGCAGATGATCTTCATTTCCGCCGGCTTCGACGGACACTACGAAGACGACATGGGCGG
TCTGAAACTGGTCGAAAAGGACTTCGCCTGGTGCACCGAACATTTGAAGAAACTGGCCGCTGAAATGTGCGAAAAGCGCA
TTGTCTCCATGCTGGAGGGCGGTTATGTGATGACCTCGCTGGCCCGTAGCGTGGGCGCACATCTGCGGGCGCTGGCAGAC
CTCTAG

Upstream 100 bases:

>100_bases
AAAGTGGGCTTTTGAGCATTATGGGTTTCCATTGTTCCAATTCAATCCGATTCTAATGCTTGAAGCGCCGGACATAATGG
GACGATAATGCCATTTCGAC

Downstream 100 bases:

>100_bases
TGCCAGCCTCCGGGTTTATGGTGGCAAGTACTGATTTCTTTAGAAAAAGAACCGGGTGGGGTAAAATCCCGCCCTCTTTT
TCATGTTTCCAACGTTTAAC

Product: histone deacetylase superfamily protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MRRFVRCFAEREQVTTTAFITHRDCQLHDMGSHHPECPQRLTAINDHLIAQGIDAYFTYYDAPLATFEQLLRVHPASHLE
RIKRASPELGVVHLDPDTAMNPHTWQAALRAAGAGCMAVDLVLNKEVENAFCAVRPPGHHCEKATPMGFCFFNNIGVAAR
HALKVHGLERVAIIDFDVHHGNGTEDCFAGDEQVLMCSIFQHPFYPYSGADKPAANMCNVPLAAGCGGEEFRDAVMQVWT
PRLKEFKPQMIFISAGFDGHYEDDMGGLKLVEKDFAWCTEHLKKLAAEMCEKRIVSMLEGGYVMTSLARSVGAHLRALAD
L

Sequences:

>Translated_321_residues
MRRFVRCFAEREQVTTTAFITHRDCQLHDMGSHHPECPQRLTAINDHLIAQGIDAYFTYYDAPLATFEQLLRVHPASHLE
RIKRASPELGVVHLDPDTAMNPHTWQAALRAAGAGCMAVDLVLNKEVENAFCAVRPPGHHCEKATPMGFCFFNNIGVAAR
HALKVHGLERVAIIDFDVHHGNGTEDCFAGDEQVLMCSIFQHPFYPYSGADKPAANMCNVPLAAGCGGEEFRDAVMQVWT
PRLKEFKPQMIFISAGFDGHYEDDMGGLKLVEKDFAWCTEHLKKLAAEMCEKRIVSMLEGGYVMTSLARSVGAHLRALAD
L
>Mature_321_residues
MRRFVRCFAEREQVTTTAFITHRDCQLHDMGSHHPECPQRLTAINDHLIAQGIDAYFTYYDAPLATFEQLLRVHPASHLE
RIKRASPELGVVHLDPDTAMNPHTWQAALRAAGAGCMAVDLVLNKEVENAFCAVRPPGHHCEKATPMGFCFFNNIGVAAR
HALKVHGLERVAIIDFDVHHGNGTEDCFAGDEQVLMCSIFQHPFYPYSGADKPAANMCNVPLAAGCGGEEFRDAVMQVWT
PRLKEFKPQMIFISAGFDGHYEDDMGGLKLVEKDFAWCTEHLKKLAAEMCEKRIVSMLEGGYVMTSLARSVGAHLRALAD
L

Specific function: Putative deacetylase [H]

COG id: COG0123

COG function: function code BQ; Deacetylases, including yeast histone deacetylase and acetoin utilization protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the histone deacetylase family [H]

Homologues:

Organism=Homo sapiens, GI20070354, Length=317, Percent_Identity=35.3312302839117, Blast_Score=161, Evalue=9e-40,
Organism=Homo sapiens, GI13128864, Length=316, Percent_Identity=35.7594936708861, Blast_Score=160, Evalue=1e-39,
Organism=Homo sapiens, GI153085395, Length=325, Percent_Identity=33.8461538461538, Blast_Score=142, Evalue=5e-34,
Organism=Homo sapiens, GI148539870, Length=315, Percent_Identity=33.968253968254, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI169234807, Length=315, Percent_Identity=33.968253968254, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI17158039, Length=246, Percent_Identity=34.9593495934959, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI30795202, Length=246, Percent_Identity=34.9593495934959, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI30795204, Length=246, Percent_Identity=34.9593495934959, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI226529806, Length=317, Percent_Identity=32.1766561514196, Blast_Score=131, Evalue=9e-31,
Organism=Homo sapiens, GI62750347, Length=326, Percent_Identity=31.5950920245399, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI62750349, Length=326, Percent_Identity=31.5950920245399, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI13128860, Length=296, Percent_Identity=25.3378378378378, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI13128862, Length=312, Percent_Identity=23.7179487179487, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI293336691, Length=268, Percent_Identity=23.5074626865672, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI209862883, Length=246, Percent_Identity=28.4552845528455, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI217272877, Length=248, Percent_Identity=28.6290322580645, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI8923769, Length=292, Percent_Identity=21.5753424657534, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17540334, Length=308, Percent_Identity=34.4155844155844, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17540332, Length=308, Percent_Identity=34.4155844155844, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI193206283, Length=308, Percent_Identity=34.4155844155844, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI25154020, Length=296, Percent_Identity=29.7297297297297, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193209491, Length=319, Percent_Identity=31.6614420062696, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI25154022, Length=296, Percent_Identity=29.3918918918919, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI17537347, Length=314, Percent_Identity=29.9363057324841, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17534739, Length=312, Percent_Identity=25.9615384615385, Blast_Score=101, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17508561, Length=303, Percent_Identity=22.4422442244224, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17561978, Length=294, Percent_Identity=23.469387755102, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324307, Length=316, Percent_Identity=31.9620253164557, Blast_Score=140, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6321244, Length=299, Percent_Identity=25.752508361204, Blast_Score=98, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6323999, Length=311, Percent_Identity=24.4372990353698, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6325141, Length=375, Percent_Identity=26.6666666666667, Blast_Score=83, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6325325, Length=126, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24642146, Length=301, Percent_Identity=34.8837209302326, Blast_Score=163, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281360899, Length=301, Percent_Identity=34.8837209302326, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642142, Length=301, Percent_Identity=35.2159468438538, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24642144, Length=301, Percent_Identity=34.8837209302326, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281360799, Length=325, Percent_Identity=31.0769230769231, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641720, Length=325, Percent_Identity=31.0769230769231, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI281360801, Length=325, Percent_Identity=31.0769230769231, Blast_Score=124, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24657891, Length=295, Percent_Identity=24.0677966101695, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644244, Length=304, Percent_Identity=23.6842105263158, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000286 [H]

Pfam domain/function: PF00850 Hist_deacetyl [H]

EC number: NA

Molecular weight: Translated: 35724; Mature: 35724

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRFVRCFAEREQVTTTAFITHRDCQLHDMGSHHPECPQRLTAINDHLIAQGIDAYFTYY
CHHHHHHHHHHHHHEEEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DAPLATFEQLLRVHPASHLERIKRASPELGVVHLDPDTAMNPHTWQAALRAAGAGCMAVD
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEH
LVLNKEVENAFCAVRPPGHHCEKATPMGFCFFNNIGVAARHALKVHGLERVAIIDFDVHH
HHHHHHHHCCEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEEEEEC
GNGTEDCFAGDEQVLMCSIFQHPFYPYSGADKPAANMCNVPLAAGCGGEEFRDAVMQVWT
CCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHC
PRLKEFKPQMIFISAGFDGHYEDDMGGLKLVEKDFAWCTEHLKKLAAEMCEKRIVSMLEG
HHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GYVMTSLARSVGAHLRALADL
CHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRRFVRCFAEREQVTTTAFITHRDCQLHDMGSHHPECPQRLTAINDHLIAQGIDAYFTYY
CHHHHHHHHHHHHHEEEEEEEECCCEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
DAPLATFEQLLRVHPASHLERIKRASPELGVVHLDPDTAMNPHTWQAALRAAGAGCMAVD
CCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEH
LVLNKEVENAFCAVRPPGHHCEKATPMGFCFFNNIGVAARHALKVHGLERVAIIDFDVHH
HHHHHHHHCCEEEECCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCEEEEEEEEEEC
GNGTEDCFAGDEQVLMCSIFQHPFYPYSGADKPAANMCNVPLAAGCGGEEFRDAVMQVWT
CCCCCHHHCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHC
PRLKEFKPQMIFISAGFDGHYEDDMGGLKLVEKDFAWCTEHLKKLAAEMCEKRIVSMLEG
HHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GYVMTSLARSVGAHLRALADL
CHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]