Click here to switch to the map view.

The map label for this gene is map [H]

Identifier: 71908102

GI number: 71908102

Start: 2683811

End: 2684635

Strand: Reverse

Name: map [H]

Synonym: Daro_2485

Alternate gene names: 71908102

Gene position: 2684635-2683811 (Counterclockwise)

Preceding gene: 71908103

Following gene: 71908101

Centisome position: 59.64

GC content: 55.76

Gene sequence:

>825_bases
ATGACTGGCGCCAAAGGTACGCCCATCCGCTCGGAGGCGGAGTTAGCCATGGCTCGGCGTGCCGGCAAGTTGGCTGCCGA
TGTTTTGTCCATGCTCGCGGAGCATGTTAAGCCAGGCGTCACGACCAATGAGCTGGACAAGCTATGCCATGACTATATCG
TCAATGTGCAACGAGCAATTCCGGCCAATATCGGCTACCACGGCTATCCCAAGACCATTTGCGCTTCAGTCAATCATGTC
GTTTGCCATGGGATTCCTTCTGACCGGAAATTGAAGAATGGCGACATCATCAACATCGACGTCGCCATCATCAAGGATGG
CTGGTTTGGCGACACCAGCCGCATGTACTTTGTTGGAGAACCGGGCATTCTGGCGAAACGGCTGGTTCGTACGACCTATG
AGGCGATGCGGGCAGGCATCGAGCAAGTGCGCCCGGGAGCGACGCTTGGCGATGTCGGTCATGCGATCCAGACTGTTGCC
CATCGCGAAGGGTTCAGTGTTGTTCGCGAGTACGGTGGTCATGGAATAGGAACGGTATATCACGATGACCTTCATGTTCT
TCACTTCGGAAAGCCCGGTGCAGGTTTGAAACTTGAGGCAGGCATGGTGTTCACCATCGAACCGATGATCAACGCTGGAA
AAGCCGAGATCAAGCACTTGCCAGATGGCTGGACTGTGGTCACCAAGGATCGGTCGCTCTCTGCTCAGTGGGAGCATATG
GTGGCGGTCACCAAGAACGGCTTCGAGGTGCTCACACCTTGGCCGGATGGCTACGGGGATTACGCCGCGATCGTGTCGTT
TCCCGAAGAACGAAGTGCTGCATAG

Upstream 100 bases:

>100_bases
CCAACCTTCGGTACGGTGAAATCTGTCGCTTGCTTATCCAGGCCGAGCACCAAGCGCTTGAAGATAGCGACCTGCCCGTT
TCATTGTCGAAGAGGGCGGC

Downstream 100 bases:

>100_bases
GTGTAGAAAACGGACTGAGCAAAATGCCAGGCAGTCCGTGCTCGCGGGGGGAGAGCGCTAGGCATGCAGCGATGTGGCGT
TGATTGGCCGGTAGCCGCTG

Product: peptidase M24A

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTGAKGTPIRSEAELAMARRAGKLAADVLSMLAEHVKPGVTTNELDKLCHDYIVNVQRAIPANIGYHGYPKTICASVNHV
VCHGIPSDRKLKNGDIINIDVAIIKDGWFGDTSRMYFVGEPGILAKRLVRTTYEAMRAGIEQVRPGATLGDVGHAIQTVA
HREGFSVVREYGGHGIGTVYHDDLHVLHFGKPGAGLKLEAGMVFTIEPMINAGKAEIKHLPDGWTVVTKDRSLSAQWEHM
VAVTKNGFEVLTPWPDGYGDYAAIVSFPEERSAA

Sequences:

>Translated_274_residues
MTGAKGTPIRSEAELAMARRAGKLAADVLSMLAEHVKPGVTTNELDKLCHDYIVNVQRAIPANIGYHGYPKTICASVNHV
VCHGIPSDRKLKNGDIINIDVAIIKDGWFGDTSRMYFVGEPGILAKRLVRTTYEAMRAGIEQVRPGATLGDVGHAIQTVA
HREGFSVVREYGGHGIGTVYHDDLHVLHFGKPGAGLKLEAGMVFTIEPMINAGKAEIKHLPDGWTVVTKDRSLSAQWEHM
VAVTKNGFEVLTPWPDGYGDYAAIVSFPEERSAA
>Mature_273_residues
TGAKGTPIRSEAELAMARRAGKLAADVLSMLAEHVKPGVTTNELDKLCHDYIVNVQRAIPANIGYHGYPKTICASVNHVV
CHGIPSDRKLKNGDIINIDVAIIKDGWFGDTSRMYFVGEPGILAKRLVRTTYEAMRAGIEQVRPGATLGDVGHAIQTVAH
REGFSVVREYGGHGIGTVYHDDLHVLHFGKPGAGLKLEAGMVFTIEPMINAGKAEIKHLPDGWTVVTKDRSLSAQWEHMV
AVTKNGFEVLTPWPDGYGDYAAIVSFPEERSAA

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=252, Percent_Identity=41.6666666666667, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI40385867, Length=247, Percent_Identity=40.080971659919, Blast_Score=194, Evalue=6e-50,
Organism=Escherichia coli, GI1786364, Length=262, Percent_Identity=54.5801526717557, Blast_Score=297, Evalue=5e-82,
Organism=Escherichia coli, GI1789275, Length=290, Percent_Identity=24.1379310344828, Blast_Score=61, Evalue=1e-10,
Organism=Caenorhabditis elegans, GI71996291, Length=253, Percent_Identity=39.9209486166008, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6323273, Length=246, Percent_Identity=39.8373983739837, Blast_Score=199, Evalue=4e-52,
Organism=Drosophila melanogaster, GI21355531, Length=250, Percent_Identity=42, Blast_Score=199, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24583427, Length=248, Percent_Identity=37.5, Blast_Score=184, Evalue=6e-47,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29735; Mature: 29604

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGAKGTPIRSEAELAMARRAGKLAADVLSMLAEHVKPGVTTNELDKLCHDYIVNVQRAI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
PANIGYHGYPKTICASVNHVVCHGIPSDRKLKNGDIINIDVAIIKDGWFGDTSRMYFVGE
CCCCCCCCCCHHHHHCCCEEEEECCCCCCEECCCCEEEEEEEEEECCCCCCCCEEEEECC
PGILAKRLVRTTYEAMRAGIEQVRPGATLGDVGHAIQTVAHREGFSVVREYGGHGIGTVY
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
HDDLHVLHFGKPGAGLKLEAGMVFTIEPMINAGKAEIKHLPDGWTVVTKDRSLSAQWEHM
ECCEEEEEECCCCCCCEEECCEEEEECCCCCCCCHHHHCCCCCCEEEEECCCCCCCHHEE
VAVTKNGFEVLTPWPDGYGDYAAIVSFPEERSAA
EEEECCCCEEECCCCCCCCCEEEEEECCHHCCCC
>Mature Secondary Structure 
TGAKGTPIRSEAELAMARRAGKLAADVLSMLAEHVKPGVTTNELDKLCHDYIVNVQRAI
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHC
PANIGYHGYPKTICASVNHVVCHGIPSDRKLKNGDIINIDVAIIKDGWFGDTSRMYFVGE
CCCCCCCCCCHHHHHCCCEEEEECCCCCCEECCCCEEEEEEEEEECCCCCCCCEEEEECC
PGILAKRLVRTTYEAMRAGIEQVRPGATLGDVGHAIQTVAHREGFSVVREYGGHGIGTVY
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEE
HDDLHVLHFGKPGAGLKLEAGMVFTIEPMINAGKAEIKHLPDGWTVVTKDRSLSAQWEHM
ECCEEEEEECCCCCCCEEECCEEEEECCCCCCCCHHHHCCCCCCEEEEECCCCCCCHHEE
VAVTKNGFEVLTPWPDGYGDYAAIVSFPEERSAA
EEEECCCCEEECCCCCCCCCEEEEEECCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]