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The map label for this gene is rocF [H]

Identifier: 71908086

GI number: 71908086

Start: 2668984

End: 2669904

Strand: Reverse

Name: rocF [H]

Synonym: Daro_2468

Alternate gene names: 71908086

Gene position: 2669904-2668984 (Counterclockwise)

Preceding gene: 71908087

Following gene: 71908085

Centisome position: 59.32

GC content: 62.87

Gene sequence:

>921_bases
ATGACCTATAATTCGCCCGCCATGAAACCCCTCGGTTCCCTGAAATACTCCCGCATTCGCATCATCGGCGCCGCCAGCGG
CCTCGGCGCGCAGGATCAGGCTTGCGAGGACGGGCCGGTGGCGTTTCATCATTCGCAGGCGTGGCATGAACTGGAGCATC
ACCCGCTGGTCGATTGGGGCAAGACCTTGTTTGCGCCGGATAATGACGGCACCTCGACGACTGCCCGGATTGCAGAATTG
TGTCGCCATCTGGCCGACGAGGTGGCGCTGACACTGCGGGCTGACGAGTTTCCGGTGGTCATCGGTGGCGATCATTCCAT
CGCCATCGGCACCTGGAGCGGCTTGGCTCGGGTGCTCGGCCAACCCTTTGGTCTGTTGTGGATTGATGCTCATCTCGACA
GCCACACGCCGGAAACCAGCTATTCCGGCGCAGTCCACGGCATGCCGCTGGCCTGCCTGCTCGGGCGTGGCGACAAGCGA
CTGCTCAATATCGGCCTGAACGGCCCGCAAGTCAGCGCGGCGCACACGGTCATCCTCGGCCCGCGCAGCTATGAACCGGA
AGAGCTTGAATTCCTGCAGCGGATGGGCGTTCGTATCATCGATAGCGAGGAAATCCAGCTGCGTGGCTTCGCCGCCTGTC
TGGACGAGGCGATAGCCATCGTTGCCGGTGCGCCGGCCGGTTTTGGCGTAACGCTGGACCTGGATGCCATTGACCCGAGG
TCGGCGCCGGGCGTCGGCAGCCCCGAGCCGGATGGCCTGACCTCGTACGACGTGCTGACGGCGATGCACTGGATTGCGGC
ACAGGCCGGCCTCAAGGCGCTGGAAATCGTCGAATACAACCCGGATCGTGATCGCCACGGCACGACGGCGGCGTTGATTT
CCAACATGATCGAGCAGATTTTGCCGGTTGGCGCAAAGTAA

Upstream 100 bases:

>100_bases
GCGGGTATCGTCTCTGGAGGCCGAAGTCGCCGAATTGCGTGCCTTGCTGCTCGAACGGAGCCGCGAATAGGCGTGCATTT
ACGGCAGTTCTGCCGTGTGC

Downstream 100 bases:

>100_bases
GCCATGGACATTGATCCTTACGAAATTCTCGATGTGGCCAAAGATTCAGGCCCGGTTGAGTGGAAACGGGCCTATCGTCG
TCTTGCCATGCGCTGGCACC

Product: arginase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MTYNSPAMKPLGSLKYSRIRIIGAASGLGAQDQACEDGPVAFHHSQAWHELEHHPLVDWGKTLFAPDNDGTSTTARIAEL
CRHLADEVALTLRADEFPVVIGGDHSIAIGTWSGLARVLGQPFGLLWIDAHLDSHTPETSYSGAVHGMPLACLLGRGDKR
LLNIGLNGPQVSAAHTVILGPRSYEPEELEFLQRMGVRIIDSEEIQLRGFAACLDEAIAIVAGAPAGFGVTLDLDAIDPR
SAPGVGSPEPDGLTSYDVLTAMHWIAAQAGLKALEIVEYNPDRDRHGTTAALISNMIEQILPVGAK

Sequences:

>Translated_306_residues
MTYNSPAMKPLGSLKYSRIRIIGAASGLGAQDQACEDGPVAFHHSQAWHELEHHPLVDWGKTLFAPDNDGTSTTARIAEL
CRHLADEVALTLRADEFPVVIGGDHSIAIGTWSGLARVLGQPFGLLWIDAHLDSHTPETSYSGAVHGMPLACLLGRGDKR
LLNIGLNGPQVSAAHTVILGPRSYEPEELEFLQRMGVRIIDSEEIQLRGFAACLDEAIAIVAGAPAGFGVTLDLDAIDPR
SAPGVGSPEPDGLTSYDVLTAMHWIAAQAGLKALEIVEYNPDRDRHGTTAALISNMIEQILPVGAK
>Mature_305_residues
TYNSPAMKPLGSLKYSRIRIIGAASGLGAQDQACEDGPVAFHHSQAWHELEHHPLVDWGKTLFAPDNDGTSTTARIAELC
RHLADEVALTLRADEFPVVIGGDHSIAIGTWSGLARVLGQPFGLLWIDAHLDSHTPETSYSGAVHGMPLACLLGRGDKRL
LNIGLNGPQVSAAHTVILGPRSYEPEELEFLQRMGVRIIDSEEIQLRGFAACLDEAIAIVAGAPAGFGVTLDLDAIDPRS
APGVGSPEPDGLTSYDVLTAMHWIAAQAGLKALEIVEYNPDRDRHGTTAALISNMIEQILPVGAK

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI10947139, Length=281, Percent_Identity=30.6049822064057, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4502215, Length=296, Percent_Identity=29.7297297297297, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI37537722, Length=230, Percent_Identity=28.695652173913, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71996843, Length=299, Percent_Identity=37.7926421404682, Blast_Score=192, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6325146, Length=222, Percent_Identity=31.5315315315315, Blast_Score=97, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24638886, Length=279, Percent_Identity=27.2401433691756, Blast_Score=81, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 32654; Mature: 32523

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYNSPAMKPLGSLKYSRIRIIGAASGLGAQDQACEDGPVAFHHSQAWHELEHHPLVDWG
CCCCCCCCCHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCC
KTLFAPDNDGTSTTARIAELCRHLADEVALTLRADEFPVVIGGDHSIAIGTWSGLARVLG
CEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCEEEEECHHHHHHHHC
QPFGLLWIDAHLDSHTPETSYSGAVHGMPLACLLGRGDKRLLNIGLNGPQVSAAHTVILG
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCEEEEEC
PRSYEPEELEFLQRMGVRIIDSEEIQLRGFAACLDEAIAIVAGAPAGFGVTLDLDAIDPR
CCCCCHHHHHHHHHCCCEEECCCCEEHHHHHHHHHHHHHEEECCCCCCEEEEEECCCCCC
SAPGVGSPEPDGLTSYDVLTAMHWIAAQAGLKALEIVEYNPDRDRHGTTAALISNMIEQI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
LPVGAK
CCCCCC
>Mature Secondary Structure 
TYNSPAMKPLGSLKYSRIRIIGAASGLGAQDQACEDGPVAFHHSQAWHELEHHPLVDWG
CCCCCCCCHHHCCCEEEEEEEEECCCCCCCCCCCCCCCEEEECCHHHHHHCCCCCCCCC
KTLFAPDNDGTSTTARIAELCRHLADEVALTLRADEFPVVIGGDHSIAIGTWSGLARVLG
CEEECCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCEEECCCCEEEEECHHHHHHHHC
QPFGLLWIDAHLDSHTPETSYSGAVHGMPLACLLGRGDKRLLNIGLNGPQVSAAHTVILG
CCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCCCCCCCCCEEEEEC
PRSYEPEELEFLQRMGVRIIDSEEIQLRGFAACLDEAIAIVAGAPAGFGVTLDLDAIDPR
CCCCCHHHHHHHHHCCCEEECCCCEEHHHHHHHHHHHHHEEECCCCCCEEEEEECCCCCC
SAPGVGSPEPDGLTSYDVLTAMHWIAAQAGLKALEIVEYNPDRDRHGTTAALISNMIEQI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
LPVGAK
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9339546 [H]