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The map label for this gene is paaG [H]

Identifier: 71907973

GI number: 71907973

Start: 2538246

End: 2539046

Strand: Reverse

Name: paaG [H]

Synonym: Daro_2354

Alternate gene names: 71907973

Gene position: 2539046-2538246 (Counterclockwise)

Preceding gene: 71907974

Following gene: 71907972

Centisome position: 56.41

GC content: 64.29

Gene sequence:

>801_bases
ATGCCTGATGGCGCAATTCTGATCAGCCGGGAGGGAGGCATCGCCACACTGACCCTCAATCGCCCGGCCAGCCGCAACCT
GCTCGACATGGAGATGGCGTTGGCCCTGCGTGCCTGTCTCGACGAAGTGGCGATCGATGCCTCGGTGCGTGCCGTCGTGT
TGCAGGCGGCCGGCAAGCACTTCATGGTCGGCGGCGATGTGAACTGGTTTCACGGGTTGCTTGATGCCGCACCGACCGAG
CGCCGGACCCAGCTCAATCGGATGATCGACGAGGTGCATGGCGCCATCGGCCGTATCCGTAGCATGGACAAGCCGGTATT
GGCCGCCGTGCGTGGCGCCGCGGCCGGCTTCGGGTTTTCGCTGATGGCCGCCTGTGATCTGGTGGTGGCTGACCGGACGG
CCTTCTTCACGCTGGCTTACAGTGGCCTGGGGGCCTCGCCGGATGGCGGTTCCACCTACAGTCTGCCGCGCCTGCTCGGG
CCGAAGCGCGCCATGGAAATGGCTCTGCTCAACGAACGCATGGATGCTGGCAGGGCGCAGGAGCTTGGCCTGATCAACCG
GGTTGTCGAGGCAGCCGATCTCGATGCGACGGTGGCTGACCTGGCCACACGACTGGCCACCGGCCCGACACTGGCCTTTG
CCCGAACCAAGCGCCTGATCAACGAATCCCTCGAACACAGCCTGGCCAAGCAGTTGCAGGCCGAGGAGCGGGGTTTTCTT
GAATCTTCACTGACCGGGGATTTTGCCGAAGGCGTTCGCGCTTTCGTGGAGAAGCGTATGCCTGAATTCCACGGGCGCTA
G

Upstream 100 bases:

>100_bases
GATGGCGAAGTCACTGCGACCATGAAGGTCCGCCGCAGCAGCATCTACAAGACCTACGAGAAGGAAATCGAGGCGATGTA
CGGCAAGGGAGGGCTGGCCA

Downstream 100 bases:

>100_bases
GCCCATCCCCTTCCTTTGCCGCTGCCGAGAGGCGGTTCGGCAAGTTATTACCTAACGCTAAAACATGACCTGAATGGGGT
CAATGGGGCTTGTTCGCCCA

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 265

Protein sequence:

>266_residues
MPDGAILISREGGIATLTLNRPASRNLLDMEMALALRACLDEVAIDASVRAVVLQAAGKHFMVGGDVNWFHGLLDAAPTE
RRTQLNRMIDEVHGAIGRIRSMDKPVLAAVRGAAAGFGFSLMAACDLVVADRTAFFTLAYSGLGASPDGGSTYSLPRLLG
PKRAMEMALLNERMDAGRAQELGLINRVVEAADLDATVADLATRLATGPTLAFARTKRLINESLEHSLAKQLQAEERGFL
ESSLTGDFAEGVRAFVEKRMPEFHGR

Sequences:

>Translated_266_residues
MPDGAILISREGGIATLTLNRPASRNLLDMEMALALRACLDEVAIDASVRAVVLQAAGKHFMVGGDVNWFHGLLDAAPTE
RRTQLNRMIDEVHGAIGRIRSMDKPVLAAVRGAAAGFGFSLMAACDLVVADRTAFFTLAYSGLGASPDGGSTYSLPRLLG
PKRAMEMALLNERMDAGRAQELGLINRVVEAADLDATVADLATRLATGPTLAFARTKRLINESLEHSLAKQLQAEERGFL
ESSLTGDFAEGVRAFVEKRMPEFHGR
>Mature_265_residues
PDGAILISREGGIATLTLNRPASRNLLDMEMALALRACLDEVAIDASVRAVVLQAAGKHFMVGGDVNWFHGLLDAAPTER
RTQLNRMIDEVHGAIGRIRSMDKPVLAAVRGAAAGFGFSLMAACDLVVADRTAFFTLAYSGLGASPDGGSTYSLPRLLGP
KRAMEMALLNERMDAGRAQELGLINRVVEAADLDATVADLATRLATGPTLAFARTKRLINESLEHSLAKQLQAEERGFLE
SSLTGDFAEGVRAFVEKRMPEFHGR

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI4757968, Length=261, Percent_Identity=28.735632183908, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI49355787, Length=261, Percent_Identity=28.735632183908, Blast_Score=104, Evalue=8e-23,
Organism=Homo sapiens, GI25453481, Length=261, Percent_Identity=28.735632183908, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI51538573, Length=261, Percent_Identity=28.735632183908, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI194097323, Length=257, Percent_Identity=28.4046692607004, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI4757966, Length=233, Percent_Identity=28.755364806867, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI51538581, Length=233, Percent_Identity=28.755364806867, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI260274832, Length=244, Percent_Identity=27.4590163934426, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI45643119, Length=244, Percent_Identity=27.4590163934426, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI260275230, Length=244, Percent_Identity=27.4590163934426, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI221136756, Length=234, Percent_Identity=28.6324786324786, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI221136753, Length=234, Percent_Identity=28.6324786324786, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI221307494, Length=234, Percent_Identity=28.6324786324786, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI116235487, Length=245, Percent_Identity=26.1224489795918, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI70995211, Length=266, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI4502327, Length=259, Percent_Identity=30.5019305019305, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI31542718, Length=253, Percent_Identity=26.4822134387352, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI20127408, Length=185, Percent_Identity=28.6486486486486, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI68989263, Length=212, Percent_Identity=26.8867924528302, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787660, Length=262, Percent_Identity=38.1679389312977, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787659, Length=263, Percent_Identity=34.6007604562738, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI221142681, Length=263, Percent_Identity=31.5589353612167, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788597, Length=255, Percent_Identity=28.6274509803922, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788682, Length=251, Percent_Identity=29.0836653386454, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790281, Length=237, Percent_Identity=26.5822784810127, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082183, Length=226, Percent_Identity=27.8761061946903, Blast_Score=73, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25145438, Length=261, Percent_Identity=32.9501915708812, Blast_Score=117, Evalue=7e-27,
Organism=Caenorhabditis elegans, GI17535521, Length=259, Percent_Identity=26.6409266409266, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17554946, Length=259, Percent_Identity=27.7992277992278, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17549921, Length=210, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17536985, Length=262, Percent_Identity=25.5725190839695, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17540714, Length=234, Percent_Identity=27.3504273504274, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17534483, Length=256, Percent_Identity=25.390625, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560910, Length=250, Percent_Identity=24.4, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17558304, Length=187, Percent_Identity=25.1336898395722, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17540306, Length=242, Percent_Identity=27.6859504132231, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144276, Length=187, Percent_Identity=26.7379679144385, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17508951, Length=187, Percent_Identity=26.7379679144385, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17508953, Length=187, Percent_Identity=26.7379679144385, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI20129971, Length=250, Percent_Identity=31.6, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24653477, Length=250, Percent_Identity=31.6, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24654903, Length=256, Percent_Identity=25.78125, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24653139, Length=259, Percent_Identity=30.5019305019305, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI19920382, Length=248, Percent_Identity=29.8387096774194, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI19922422, Length=264, Percent_Identity=25.3787878787879, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357171, Length=263, Percent_Identity=25.0950570342205, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24650670, Length=258, Percent_Identity=26.3565891472868, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753
- InterPro:   IPR011968 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 28534; Mature: 28403

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDGAILISREGGIATLTLNRPASRNLLDMEMALALRACLDEVAIDASVRAVVLQAAGKH
CCCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FMVGGDVNWFHGLLDAAPTERRTQLNRMIDEVHGAIGRIRSMDKPVLAAVRGAAAGFGFS
EEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
LMAACDLVVADRTAFFTLAYSGLGASPDGGSTYSLPRLLGPKRAMEMALLNERMDAGRAQ
HHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCHH
ELGLINRVVEAADLDATVADLATRLATGPTLAFARTKRLINESLEHSLAKQLQAEERGFL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESSLTGDFAEGVRAFVEKRMPEFHGR
HHHCCCHHHHHHHHHHHHHCHHHCCC
>Mature Secondary Structure 
PDGAILISREGGIATLTLNRPASRNLLDMEMALALRACLDEVAIDASVRAVVLQAAGKH
CCCCEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
FMVGGDVNWFHGLLDAAPTERRTQLNRMIDEVHGAIGRIRSMDKPVLAAVRGAAAGFGFS
EEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHH
LMAACDLVVADRTAFFTLAYSGLGASPDGGSTYSLPRLLGPKRAMEMALLNERMDAGRAQ
HHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHCHHHHHHHHHHHHHHCCCCHH
ELGLINRVVEAADLDATVADLATRLATGPTLAFARTKRLINESLEHSLAKQLQAEERGFL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESSLTGDFAEGVRAFVEKRMPEFHGR
HHHCCCHHHHHHHHHHHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]