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The map label for this gene is rssA [H]

Identifier: 71907916

GI number: 71907916

Start: 2479392

End: 2480807

Strand: Reverse

Name: rssA [H]

Synonym: Daro_2297

Alternate gene names: 71907916

Gene position: 2480807-2479392 (Counterclockwise)

Preceding gene: 71907917

Following gene: 71907915

Centisome position: 55.12

GC content: 56.0

Gene sequence:

>1416_bases
ATGGATGGTTTCAAAAAACGTCTGAACGAGTCGGTTCAGTTCAAGCTGTCCTTTTCGCTGTCGCTAGCCATTTTGGTTAT
TGCGGTGGTGGCGGGCATCTTTTCCTTCGTTTCCGCATTCGACGAAGCTCACGAGCTACAAGACGACATGCTGCGCCAAG
TTGCGGCGTTGTTTGATCGGCAACACCTTCCGCTTGCACATCTTGGAGACGATGGCCGCGCCAAAGACAGCGATGAGGAG
TCACGTGTAGTCGTTCAATATCTTGCAGATGATGGCAAGGCGGCCGGGAAGGGCGATGCAGGCGTACCGCTGCCACTACC
GATTACGCTGCCCGATGGTCTGCATACGCTTGATGTCAGCGGCGAGCCGTTCCGTGTGCTGGTCAAAACAACGTCCAACG
GCGAGCGAATTGCCGTGGCGCAAGAAACCGGCGTTCGCGACGAAATTGCACGCGACAGCGCCTTGCGCACATTGATGCCG
TTTCTTATCTTGGTTCCCATCCTGCTTTTGATCGTGGCTGACCTTGTGCGCAAGATGTTCCGGCCCATTGCTTCTTTGTC
GGCAGAAATTGACCAACGCGCCGAACAAGAATTACATCCCATTGAGGACAGCCATCTTCCTGCCGAAGTGCGCCCGTTCG
TGGTGGCGATCAACCGTCTGCTTGCCCGCGTTGACCAGTCAATGGAAACCCAGCGCCGGTTTGTCGCGGATGCGGCGCAT
GAGCTTCGATCCCCGCTTACCGCCTTGTCACTGCAAGCGGAGCGACTGGATCAGGCGGATATGTCTGACCTCGCGCGTGA
ACGTCTCATGACATTGCGCCGAGGCATAGAGCGTGGCCGTAACCTGCTGGATCAACTTCTCACCTTGGCCAAGGCTCAGG
CTGCACTCGACCGACCCAAGTCGCCTGTATCGGTGCAGCACGTTTATCGACGCGTGCTGGAAGACCTTATGCCGCTGGCC
GAGGACAAGCACATCGACATTGGCGTCGAAGGAGAGCAAGACGCCCAACTCTGGGTGAACGAACTGGATGTAATTGCCGT
AGTCAAGAATTTAGTCGATAACGCCATTCGATACACGCCGGATGGTGGCAGGGTTGATCTTTCTGTCACCACGGAGGAAG
GCCGCGCAATACTGAGAATCCAAGACTCAGGGCCAGGGATTCAAGTTACTGAGCGAGAGCGGGTGTTTGACCCGTTTTAT
CGCACCCTTGGGAGCGATCAAGTCGGGTCAGGTCTGGGCCTTTCCATTGTCAAGGCAGTCACGGACCGAATTGGCGCTGA
GATTCACCTGGGGTTCTCAGACGAAGTGAGGTATTCCGGCCTGTGTGTCCGCGTGCACGTGCCGATGGCTAAACCACTTC
AAAGGGTGCCTCAGAAAACGGAAAATCAACGTCCTTTACGTCACGACGCCGATTGA

Upstream 100 bases:

>100_bases
GATGGGGTGAAGAGGTCGAGAGCAACGCCGTCGAATTCCTGATCCATGCACTGCGGCGCAAGCTGGGCGGCGAAGTCATC
AAGAATGTCAGGGGGGTTGG

Downstream 100 bases:

>100_bases
ATTTGGTATGACCGGAAAGTTTTAATCAGCCAAAATTCAGTAATTCACCAAAGGGAGAATATATGGCGACATCTACCGGC
TGGTTTTATTGGGCAATTCT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MDGFKKRLNESVQFKLSFSLSLAILVIAVVAGIFSFVSAFDEAHELQDDMLRQVAALFDRQHLPLAHLGDDGRAKDSDEE
SRVVVQYLADDGKAAGKGDAGVPLPLPITLPDGLHTLDVSGEPFRVLVKTTSNGERIAVAQETGVRDEIARDSALRTLMP
FLILVPILLLIVADLVRKMFRPIASLSAEIDQRAEQELHPIEDSHLPAEVRPFVVAINRLLARVDQSMETQRRFVADAAH
ELRSPLTALSLQAERLDQADMSDLARERLMTLRRGIERGRNLLDQLLTLAKAQAALDRPKSPVSVQHVYRRVLEDLMPLA
EDKHIDIGVEGEQDAQLWVNELDVIAVVKNLVDNAIRYTPDGGRVDLSVTTEEGRAILRIQDSGPGIQVTERERVFDPFY
RTLGSDQVGSGLGLSIVKAVTDRIGAEIHLGFSDEVRYSGLCVRVHVPMAKPLQRVPQKTENQRPLRHDAD

Sequences:

>Translated_471_residues
MDGFKKRLNESVQFKLSFSLSLAILVIAVVAGIFSFVSAFDEAHELQDDMLRQVAALFDRQHLPLAHLGDDGRAKDSDEE
SRVVVQYLADDGKAAGKGDAGVPLPLPITLPDGLHTLDVSGEPFRVLVKTTSNGERIAVAQETGVRDEIARDSALRTLMP
FLILVPILLLIVADLVRKMFRPIASLSAEIDQRAEQELHPIEDSHLPAEVRPFVVAINRLLARVDQSMETQRRFVADAAH
ELRSPLTALSLQAERLDQADMSDLARERLMTLRRGIERGRNLLDQLLTLAKAQAALDRPKSPVSVQHVYRRVLEDLMPLA
EDKHIDIGVEGEQDAQLWVNELDVIAVVKNLVDNAIRYTPDGGRVDLSVTTEEGRAILRIQDSGPGIQVTERERVFDPFY
RTLGSDQVGSGLGLSIVKAVTDRIGAEIHLGFSDEVRYSGLCVRVHVPMAKPLQRVPQKTENQRPLRHDAD
>Mature_471_residues
MDGFKKRLNESVQFKLSFSLSLAILVIAVVAGIFSFVSAFDEAHELQDDMLRQVAALFDRQHLPLAHLGDDGRAKDSDEE
SRVVVQYLADDGKAAGKGDAGVPLPLPITLPDGLHTLDVSGEPFRVLVKTTSNGERIAVAQETGVRDEIARDSALRTLMP
FLILVPILLLIVADLVRKMFRPIASLSAEIDQRAEQELHPIEDSHLPAEVRPFVVAINRLLARVDQSMETQRRFVADAAH
ELRSPLTALSLQAERLDQADMSDLARERLMTLRRGIERGRNLLDQLLTLAKAQAALDRPKSPVSVQHVYRRVLEDLMPLA
EDKHIDIGVEGEQDAQLWVNELDVIAVVKNLVDNAIRYTPDGGRVDLSVTTEEGRAILRIQDSGPGIQVTERERVFDPFY
RTLGSDQVGSGLGLSIVKAVTDRIGAEIHLGFSDEVRYSGLCVRVHVPMAKPLQRVPQKTENQRPLRHDAD

Specific function: Member of the two-component regulatory system rssA/rssB involved in regulation of swarming motility which has been shown to be inhibited by saturated fatty acids. RssA/rssB regulates cellular fatty acid composition, hemolysin production and cell surface t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=459, Percent_Identity=30.2832244008715, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1790551, Length=288, Percent_Identity=30.9027777777778, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788279, Length=320, Percent_Identity=27.5, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786783, Length=271, Percent_Identity=27.6752767527675, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=31.2775330396476, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789808, Length=312, Percent_Identity=26.6025641025641, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=26.3779527559055, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=25.089605734767, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1787894, Length=233, Percent_Identity=30.0429184549356, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790861, Length=302, Percent_Identity=26.158940397351, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787374, Length=288, Percent_Identity=27.0833333333333, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082128, Length=313, Percent_Identity=26.8370607028754, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081816, Length=268, Percent_Identity=24.6268656716418, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=213, Percent_Identity=26.2910798122066, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786912, Length=219, Percent_Identity=27.8538812785388, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=220, Percent_Identity=24.0909090909091, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 52216; Mature: 52216

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGFKKRLNESVQFKLSFSLSLAILVIAVVAGIFSFVSAFDEAHELQDDMLRQVAALFDR
CCHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QHLPLAHLGDDGRAKDSDEESRVVVQYLADDGKAAGKGDAGVPLPLPITLPDGLHTLDVS
CCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCEEECCC
GEPFRVLVKTTSNGERIAVAQETGVRDEIARDSALRTLMPFLILVPILLLIVADLVRKMF
CCCEEEEEEECCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPIASLSAEIDQRAEQELHPIEDSHLPAEVRPFVVAINRLLARVDQSMETQRRFVADAAH
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRSPLTALSLQAERLDQADMSDLARERLMTLRRGIERGRNLLDQLLTLAKAQAALDRPK
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SPVSVQHVYRRVLEDLMPLAEDKHIDIGVEGEQDAQLWVNELDVIAVVKNLVDNAIRYTP
CCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECC
DGGRVDLSVTTEEGRAILRIQDSGPGIQVTERERVFDPFYRTLGSDQVGSGLGLSIVKAV
CCCEEEEEEECCCCCEEEEEECCCCCCEEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TDRIGAEIHLGFSDEVRYSGLCVRVHVPMAKPLQRVPQKTENQRPLRHDAD
HHHCCCEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MDGFKKRLNESVQFKLSFSLSLAILVIAVVAGIFSFVSAFDEAHELQDDMLRQVAALFDR
CCHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
QHLPLAHLGDDGRAKDSDEESRVVVQYLADDGKAAGKGDAGVPLPLPITLPDGLHTLDVS
CCCCHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEECCCCCEEECCC
GEPFRVLVKTTSNGERIAVAQETGVRDEIARDSALRTLMPFLILVPILLLIVADLVRKMF
CCCEEEEEEECCCCCEEEEEHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RPIASLSAEIDQRAEQELHPIEDSHLPAEVRPFVVAINRLLARVDQSMETQRRFVADAAH
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELRSPLTALSLQAERLDQADMSDLARERLMTLRRGIERGRNLLDQLLTLAKAQAALDRPK
HHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SPVSVQHVYRRVLEDLMPLAEDKHIDIGVEGEQDAQLWVNELDVIAVVKNLVDNAIRYTP
CCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECC
DGGRVDLSVTTEEGRAILRIQDSGPGIQVTERERVFDPFYRTLGSDQVGSGLGLSIVKAV
CCCEEEEEEECCCCCEEEEEECCCCCCEEECHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
TDRIGAEIHLGFSDEVRYSGLCVRVHVPMAKPLQRVPQKTENQRPLRHDAD
HHHCCCEEEECCCCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA