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The map label for this gene is cadC [H]

Identifier: 71907901

GI number: 71907901

Start: 2466403

End: 2466753

Strand: Reverse

Name: cadC [H]

Synonym: Daro_2281

Alternate gene names: 71907901

Gene position: 2466753-2466403 (Counterclockwise)

Preceding gene: 71907902

Following gene: 71907900

Centisome position: 54.8

GC content: 60.68

Gene sequence:

>351_bases
ATGTGCAACGTCACCTGCTTCGAGCAGGAGAAAGTCGCCCGCATCAAGGCTGCACTCGCCGAGGACGAAGCGGCATTGCC
GCAGCTCGCTGAACTCTACAAGCTTCTGGGCAACGTCACGCGCCTCAAGATTCTCCTGGCTCTTGCCCAGGGCGAATTGT
GCGTCTGTGACGTGGCCCATGTGCTGGGCCTCACTGTCGCAGCCACCTCTCATCAACTGAAGCTGCTCCGTGACCAGGGC
TGGCTCGCCATGCGCAACGACGGGAAGATGGTTTATTACCGCCTGAACAGCCCGGGGCTCCTCGAAGCCCTGAAGGGCGA
CCTGTGCCTGCTTGAGGAACGTATCGCATGA

Upstream 100 bases:

>100_bases
ACCCGACCCTTGCCTGCGTGTCTATGTCATCATATCATTTTCGCAAACGTCTAAATGAGAGGTGGTCTTGAAACCGGCAG
CCAACGTGATCGAGAGTCCG

Downstream 100 bases:

>100_bases
GTACGCCTGGACTCGACGCCATACAGGAGCAGATGCACCTGGCCATGGCGGCGACCAAGTGCCACCGCTGTGGCTGCTTC
CAGGATACGGTGCAGGCGCT

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: Cadmium resistance regulatory protein [H]

Number of amino acids: Translated: 116; Mature: 116

Protein sequence:

>116_residues
MCNVTCFEQEKVARIKAALAEDEAALPQLAELYKLLGNVTRLKILLALAQGELCVCDVAHVLGLTVAATSHQLKLLRDQG
WLAMRNDGKMVYYRLNSPGLLEALKGDLCLLEERIA

Sequences:

>Translated_116_residues
MCNVTCFEQEKVARIKAALAEDEAALPQLAELYKLLGNVTRLKILLALAQGELCVCDVAHVLGLTVAATSHQLKLLRDQG
WLAMRNDGKMVYYRLNSPGLLEALKGDLCLLEERIA
>Mature_116_residues
MCNVTCFEQEKVARIKAALAEDEAALPQLAELYKLLGNVTRLKILLALAQGELCVCDVAHVLGLTVAATSHQLKLLRDQG
WLAMRNDGKMVYYRLNSPGLLEALKGDLCLLEERIA

Specific function: Metal-binding repressor for the cad operon. Involved in resistance to heavy metals, such as cadmium, bismuth, zinc or lead. Metal binding causes the repressor to dissociate from the DNA [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR018334
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12780; Mature: 12780

Theoretical pI: Translated: 6.49; Mature: 6.49

Prosite motif: PS00846 HTH_ARSR_1 ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCNVTCFEQEKVARIKAALAEDEAALPQLAELYKLLGNVTRLKILLALAQGELCVCDVAH
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEHHHHHH
VLGLTVAATSHQLKLLRDQGWLAMRNDGKMVYYRLNSPGLLEALKGDLCLLEERIA
HHHHHHHCCCHHHHEEECCCCEEEECCCCEEEEEECCCCHHHHHCCCHHHHHHHCC
>Mature Secondary Structure
MCNVTCFEQEKVARIKAALAEDEAALPQLAELYKLLGNVTRLKILLALAQGELCVCDVAH
CCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCEEHHHHHH
VLGLTVAATSHQLKLLRDQGWLAMRNDGKMVYYRLNSPGLLEALKGDLCLLEERIA
HHHHHHHCCCHHHHEEECCCCEEEECCCCEEEEEECCCCHHHHHCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8188605; 8188606 [H]