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The map label for this gene is aspC [H]

Identifier: 71907631

GI number: 71907631

Start: 2156184

End: 2157392

Strand: Reverse

Name: aspC [H]

Synonym: Daro_2002

Alternate gene names: 71907631

Gene position: 2157392-2156184 (Counterclockwise)

Preceding gene: 71907634

Following gene: 71907629

Centisome position: 47.93

GC content: 60.63

Gene sequence:

>1209_bases
ATGTCCTCTTCGATCTTCGCTGCGGTGGAAATGGCCCCGCGCGATCCTATCCTGGGTCTGAATGAAGCTTTCAATGCTGA
TGCGCGCACTACCAAGGTTAACCTTGGCGTCGGCGTGTATTTCGACGACAACGGCAAGATTCCGCTGCTGGCCGCCGTCA
AGGCCGCTGAGGACGTCCGCGTCAAGGCCGCACTGCCGCGCGGCTATCAGCCGATCGAAGGCAATCCGGCCTACAACACG
GCTGTCCAGAACCTGTTGCTCGGCAAGGACTCCGCACTGATCGCCAACGGCCAGGTCATCACCGCTCAGGCCCTCGGTGG
CACAGGCGCCCTGAAAATTGGCGCCGACTACCTGAAGCGCCTGAATCCAAACGCCAAGGTATACATCAGCGACCCATCCT
GGGAAAACCATCGCGCCCTGTTCGAATCCGCCGGCTTCGTCGTAGAAAACTATCCGTATTACGACGCCGCCACGCGTGGC
GTTAACTTCGAGGGAATGAAGGCCTGCCTGAAGGGTCTGGATGCAGGCTCGGTCATCATCCTTCACGCTTGCTGCCACAA
CCCGACCGGCGCCGATTTGTCGGATGCCCAATGGAGCGAAGTTGTCGCAATCTGCCAGGAGCGCGGTTTGGTACCCTTCC
TCGACATGGCCTACCAGGGCTTTGCCGATGGTATCGATGCCGACGCCGTCGCTGTTCGTGCTTTCTCCGCTTCCGGCCTG
CAATTCTTCGCTTCCAGCTCGTTCTCCAAGAACTTCTCGCTTTATGGCGAGCGCGTCGGCGCCCTGTCCATCGTCACGGC
CGGCAAGGAAGAATCTGCTCGCGTCATGTCGCAGGTCAAGCGCGTCATCCGCACCAATTACTCCAACCCGCCGACCCATG
GCGGTGCGCTAGTGGCTGGTGTTCTGGCGTCCGCGGAACTACGCCAGATGTGGGAAACCGAGCTGGCCGGCATGCGTGAC
CGCATCCGCGCCATGCGCACCGGTCTGGTCGATGCCATCAAGGCACAAGGCGTGGCGCAGGATTTCTCCTTCGTTGCCCA
GCAGCGCGGTATGTTCTCCTATACCGGCCTGACGGCTGCCCAGGTCGAACGCATGCGTGAAGAATTCGGCATCTACGCCG
TGTCGACCGGCCGTATCTGCCTGGCTGCGCTGAATACCAAGAATCTGGATTACGTGGCCAAGGCGATTGCCGCAGTTACC
AAGCCCTGA

Upstream 100 bases:

>100_bases
CGTGCCGGTGTTGGTTTCGCTCATGTTAAAATTCTTCGGTTTCTCGTCGCATAGCCGGTTGGCTGCGCGAACATTATTCG
TATTATTCCACGGAGTCTCT

Downstream 100 bases:

>100_bases
TCAACATCAAGTTGATTGGCAAAAAGGGCGGAACCAAGGTTCCGCCCTTTTTTATTTTTGGGTGGTGGCACTCAAGTCAG
GCAACGTACCAAAAATCCGA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSSSIFAAVEMAPRDPILGLNEAFNADARTTKVNLGVGVYFDDNGKIPLLAAVKAAEDVRVKAALPRGYQPIEGNPAYNT
AVQNLLLGKDSALIANGQVITAQALGGTGALKIGADYLKRLNPNAKVYISDPSWENHRALFESAGFVVENYPYYDAATRG
VNFEGMKACLKGLDAGSVIILHACCHNPTGADLSDAQWSEVVAICQERGLVPFLDMAYQGFADGIDADAVAVRAFSASGL
QFFASSSFSKNFSLYGERVGALSIVTAGKEESARVMSQVKRVIRTNYSNPPTHGGALVAGVLASAELRQMWETELAGMRD
RIRAMRTGLVDAIKAQGVAQDFSFVAQQRGMFSYTGLTAAQVERMREEFGIYAVSTGRICLAALNTKNLDYVAKAIAAVT
KP

Sequences:

>Translated_402_residues
MSSSIFAAVEMAPRDPILGLNEAFNADARTTKVNLGVGVYFDDNGKIPLLAAVKAAEDVRVKAALPRGYQPIEGNPAYNT
AVQNLLLGKDSALIANGQVITAQALGGTGALKIGADYLKRLNPNAKVYISDPSWENHRALFESAGFVVENYPYYDAATRG
VNFEGMKACLKGLDAGSVIILHACCHNPTGADLSDAQWSEVVAICQERGLVPFLDMAYQGFADGIDADAVAVRAFSASGL
QFFASSSFSKNFSLYGERVGALSIVTAGKEESARVMSQVKRVIRTNYSNPPTHGGALVAGVLASAELRQMWETELAGMRD
RIRAMRTGLVDAIKAQGVAQDFSFVAQQRGMFSYTGLTAAQVERMREEFGIYAVSTGRICLAALNTKNLDYVAKAIAAVT
KP
>Mature_401_residues
SSSIFAAVEMAPRDPILGLNEAFNADARTTKVNLGVGVYFDDNGKIPLLAAVKAAEDVRVKAALPRGYQPIEGNPAYNTA
VQNLLLGKDSALIANGQVITAQALGGTGALKIGADYLKRLNPNAKVYISDPSWENHRALFESAGFVVENYPYYDAATRGV
NFEGMKACLKGLDAGSVIILHACCHNPTGADLSDAQWSEVVAICQERGLVPFLDMAYQGFADGIDADAVAVRAFSASGLQ
FFASSSFSKNFSLYGERVGALSIVTAGKEESARVMSQVKRVIRTNYSNPPTHGGALVAGVLASAELRQMWETELAGMRDR
IRAMRTGLVDAIKAQGVAQDFSFVAQQRGMFSYTGLTAAQVERMREEFGIYAVSTGRICLAALNTKNLDYVAKAIAAVTK
P

Specific function: Biosynthesis of Phe, Tyr, Asp and Leu. [C]

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=398, Percent_Identity=43.4673366834171, Blast_Score=341, Evalue=6e-94,
Organism=Homo sapiens, GI4504067, Length=407, Percent_Identity=42.014742014742, Blast_Score=318, Evalue=8e-87,
Organism=Homo sapiens, GI117414139, Length=398, Percent_Identity=24.8743718592965, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1790488, Length=398, Percent_Identity=50.5025125628141, Blast_Score=407, Evalue=1e-115,
Organism=Escherichia coli, GI1787159, Length=395, Percent_Identity=46.0759493670886, Blast_Score=386, Evalue=1e-108,
Organism=Caenorhabditis elegans, GI71981858, Length=397, Percent_Identity=41.8136020151133, Blast_Score=348, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI25147133, Length=399, Percent_Identity=43.859649122807, Blast_Score=343, Evalue=1e-94,
Organism=Caenorhabditis elegans, GI17569539, Length=396, Percent_Identity=38.3838383838384, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17569537, Length=398, Percent_Identity=31.6582914572864, Blast_Score=211, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17550384, Length=264, Percent_Identity=36.7424242424242, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=42.7230046948357, Blast_Score=181, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6323055, Length=411, Percent_Identity=37.712895377129, Blast_Score=299, Evalue=5e-82,
Organism=Saccharomyces cerevisiae, GI6322743, Length=437, Percent_Identity=32.2654462242563, Blast_Score=230, Evalue=4e-61,
Organism=Drosophila melanogaster, GI24580972, Length=402, Percent_Identity=45.0248756218905, Blast_Score=352, Evalue=2e-97,
Organism=Drosophila melanogaster, GI24580970, Length=403, Percent_Identity=44.9131513647643, Blast_Score=352, Evalue=3e-97,
Organism=Drosophila melanogaster, GI19920542, Length=394, Percent_Identity=45.1776649746193, Blast_Score=345, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24654046, Length=402, Percent_Identity=42.2885572139304, Blast_Score=310, Evalue=1e-84,
Organism=Drosophila melanogaster, GI19922362, Length=402, Percent_Identity=42.2885572139304, Blast_Score=310, Evalue=1e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42943; Mature: 42812

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSIFAAVEMAPRDPILGLNEAFNADARTTKVNLGVGVYFDDNGKIPLLAAVKAAEDVR
CCCCEEEEEEECCCCCCCCCHHHCCCCCCEEEEEEEEEEEECCCCCEEEEEEHHHHHCCE
VKAALPRGYQPIEGNPAYNTAVQNLLLGKDSALIANGQVITAQALGGTGALKIGADYLKR
EEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCEEEEEEECCCCCEEEECHHHHHH
LNPNAKVYISDPSWENHRALFESAGFVVENYPYYDAATRGVNFEGMKACLKGLDAGSVII
CCCCCEEEECCCCCCHHHHHHHHCCCEEECCCCCHHHHCCCCHHHHHHHHHCCCCCCEEE
LHACCHNPTGADLSDAQWSEVVAICQERGLVPFLDMAYQGFADGIDADAVAVRAFSASGL
EEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHEEEECCCCCH
QFFASSSFSKNFSLYGERVGALSIVTAGKEESARVMSQVKRVIRTNYSNPPTHGGALVAG
HHHHCCCCCCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VLASAELRQMWETELAGMRDRIRAMRTGLVDAIKAQGVAQDFSFVAQQRGMFSYTGLTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCHH
QVERMREEFGIYAVSTGRICLAALNTKNLDYVAKAIAAVTKP
HHHHHHHHHCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSSIFAAVEMAPRDPILGLNEAFNADARTTKVNLGVGVYFDDNGKIPLLAAVKAAEDVR
CCCEEEEEEECCCCCCCCCHHHCCCCCCEEEEEEEEEEEECCCCCEEEEEEHHHHHCCE
VKAALPRGYQPIEGNPAYNTAVQNLLLGKDSALIANGQVITAQALGGTGALKIGADYLKR
EEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEECCEEEEEEECCCCCEEEECHHHHHH
LNPNAKVYISDPSWENHRALFESAGFVVENYPYYDAATRGVNFEGMKACLKGLDAGSVII
CCCCCEEEECCCCCCHHHHHHHHCCCEEECCCCCHHHHCCCCHHHHHHHHHCCCCCCEEE
LHACCHNPTGADLSDAQWSEVVAICQERGLVPFLDMAYQGFADGIDADAVAVRAFSASGL
EEEECCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHEEEECCCCCH
QFFASSSFSKNFSLYGERVGALSIVTAGKEESARVMSQVKRVIRTNYSNPPTHGGALVAG
HHHHCCCCCCCHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
VLASAELRQMWETELAGMRDRIRAMRTGLVDAIKAQGVAQDFSFVAQQRGMFSYTGLTAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEECCCCHH
QVERMREEFGIYAVSTGRICLAALNTKNLDYVAKAIAAVTKP
HHHHHHHHHCEEEEECCCEEEEEECCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8808952 [H]