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The map label for this gene is serB [H]

Identifier: 71907591

GI number: 71907591

Start: 2109117

End: 2109956

Strand: Reverse

Name: serB [H]

Synonym: Daro_1962

Alternate gene names: 71907591

Gene position: 2109956-2109117 (Counterclockwise)

Preceding gene: 71907592

Following gene: 71907575

Centisome position: 46.88

GC content: 61.43

Gene sequence:

>840_bases
ATGAACCTGATCATCCAGGGCGGCGCCCTACCCACCTTTTTGCTCGAACGTATCGTCGCGGCGACCGGCGCCATAGCCGT
CGAACCCCGACCACCGCAGGTTGTCCGGCTGAAAGGTGCAACTCGCACCCCGGATTTCGATGCCCTGATTCCGCTGATCG
AAGCCGAGAAGCTCGACTGGGCGTTCGCCGAAGCCGACAAGAAGCTGTCCGACTTCGGCCTGATCTGCTTCGACATGGAT
TCGACGCTGATCACCATTGAATGCATCGACGAACTGGCTGATTTCGCCGGCAAAAAGGACGAAGTGTCGGCCGTCACCGA
AGCGGCCATGCGCGGCGAAATCGATTACCGCGAAAGCCTGCGCCGCCGCCTGTCGCTGCTGGCCGGCCTGGATGCCCGCG
TCCTGGCCAGGGTTTTCGGCGAACGCCTGCTGCTCTCACCCGGTGCCCGCGAACTCCTCGAAGCCTGCCAGAACGCTGGC
CTGCGCACCGCAATCCTGTCTGGGGGATTTACCTATTTCACCGAGCGTCTGCGTATCGAACTGGGTTTCGACTTTGCTAC
GTCAAACGAACTGGAAATTTCCGGCGGCAAGCTGACCGGACGCGTCGTCGGCGATATTGTCGATGCCACCGCCAAGGCCC
ATCACCTCGCTCGCCTGACCGATGAACTGGGCCTGAAGAAGGAACAGGTCATCGCCTGTGGCGACGGTGCCAATGACTTG
ATGATGATGGCCCAAGCCGGCCTGTCGGTCGCTTTCCGTGCCAAGCCGGCCACCCGTGCCAAGGCCGACGTGGCCATCAA
TTTCGGTGGGCTGGATTCGCTGCTCAATCTGTTCGACTGA

Upstream 100 bases:

>100_bases
TCGGTGGCATACTGGGTGCCCTCGCCATCGGCATATTCCTTCGTTTCAAGCGTGGCCGCGTCGCGAACTGACGATGGCCG
GATTTGCCTAGACTGACACC

Downstream 100 bases:

>100_bases
GCAGCGGGCAGTCAGGTCTTCCTGACCAGCTGCTTGGCAAACGCGGCGTCGTTCTTGGTGACGCGAGGTACAACTTGCGG
CCCGGTGGCATTGACCAGAC

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MNLIIQGGALPTFLLERIVAATGAIAVEPRPPQVVRLKGATRTPDFDALIPLIEAEKLDWAFAEADKKLSDFGLICFDMD
STLITIECIDELADFAGKKDEVSAVTEAAMRGEIDYRESLRRRLSLLAGLDARVLARVFGERLLLSPGARELLEACQNAG
LRTAILSGGFTYFTERLRIELGFDFATSNELEISGGKLTGRVVGDIVDATAKAHHLARLTDELGLKKEQVIACGDGANDL
MMMAQAGLSVAFRAKPATRAKADVAINFGGLDSLLNLFD

Sequences:

>Translated_279_residues
MNLIIQGGALPTFLLERIVAATGAIAVEPRPPQVVRLKGATRTPDFDALIPLIEAEKLDWAFAEADKKLSDFGLICFDMD
STLITIECIDELADFAGKKDEVSAVTEAAMRGEIDYRESLRRRLSLLAGLDARVLARVFGERLLLSPGARELLEACQNAG
LRTAILSGGFTYFTERLRIELGFDFATSNELEISGGKLTGRVVGDIVDATAKAHHLARLTDELGLKKEQVIACGDGANDL
MMMAQAGLSVAFRAKPATRAKADVAINFGGLDSLLNLFD
>Mature_279_residues
MNLIIQGGALPTFLLERIVAATGAIAVEPRPPQVVRLKGATRTPDFDALIPLIEAEKLDWAFAEADKKLSDFGLICFDMD
STLITIECIDELADFAGKKDEVSAVTEAAMRGEIDYRESLRRRLSLLAGLDARVLARVFGERLLLSPGARELLEACQNAG
LRTAILSGGFTYFTERLRIELGFDFATSNELEISGGKLTGRVVGDIVDATAKAHHLARLTDELGLKKEQVIACGDGANDL
MMMAQAGLSVAFRAKPATRAKADVAINFGGLDSLLNLFD

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=29.6703296703297, Blast_Score=76, Evalue=3e-14,
Organism=Escherichia coli, GI1790849, Length=244, Percent_Identity=46.3114754098361, Blast_Score=183, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6321647, Length=206, Percent_Identity=38.3495145631068, Blast_Score=145, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24661601, Length=197, Percent_Identity=27.9187817258883, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 30098; Mature: 30098

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIIQGGALPTFLLERIVAATGAIAVEPRPPQVVRLKGATRTPDFDALIPLIEAEKLDW
CCEEEECCCCHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCH
AFAEADKKLSDFGLICFDMDSTLITIECIDELADFAGKKDEVSAVTEAAMRGEIDYRESL
HHHHHHCCHHHCCEEEEECCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
RRRLSLLAGLDARVLARVFGERLLLSPGARELLEACQNAGLRTAILSGGFTYFTERLRIE
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEHHCCCHHHHHEEEEEE
LGFDFATSNELEISGGKLTGRVVGDIVDATAKAHHLARLTDELGLKKEQVIACGDGANDL
EECCEECCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCHHH
MMMAQAGLSVAFRAKPATRAKADVAINFGGLDSLLNLFD
HHHHHCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHCC
>Mature Secondary Structure
MNLIIQGGALPTFLLERIVAATGAIAVEPRPPQVVRLKGATRTPDFDALIPLIEAEKLDW
CCEEEECCCCHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCH
AFAEADKKLSDFGLICFDMDSTLITIECIDELADFAGKKDEVSAVTEAAMRGEIDYRESL
HHHHHHCCHHHCCEEEEECCCCEEEHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHH
RRRLSLLAGLDARVLARVFGERLLLSPGARELLEACQNAGLRTAILSGGFTYFTERLRIE
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEHHCCCHHHHHEEEEEE
LGFDFATSNELEISGGKLTGRVVGDIVDATAKAHHLARLTDELGLKKEQVIACGDGANDL
EECCEECCCEEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCHHH
MMMAQAGLSVAFRAKPATRAKADVAINFGGLDSLLNLFD
HHHHHCCCEEEEECCCCCCCCCEEEEEECCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]