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The map label for this gene is luxQ [H]

Identifier: 71907451

GI number: 71907451

Start: 1958582

End: 1960330

Strand: Reverse

Name: luxQ [H]

Synonym: Daro_1822

Alternate gene names: 71907451

Gene position: 1960330-1958582 (Counterclockwise)

Preceding gene: 71907452

Following gene: 71907450

Centisome position: 43.55

GC content: 59.29

Gene sequence:

>1749_bases
ATGATGCCCGCTCCGCCACAGCCCATCGACCGGGATGTTCCCTTGGACGAAGAGTCGACGGCCAAGATCGGCTTTCTCTA
CAGCGTATTCCTGCTGGCCGGGCTAGTCGCCTTCGTGATGGGGTTTGTCCGCTGGCAAACCAGCGTCGCCATGGGATTCG
TCGATTTTGGCTTCGCCGGCTTCAACTTCGGACTGCTGCTCTACCTGCGGCGTAACCCGCAAAAGGTCGAAATCGTCAGC
ACCTTGTCGCTGTCGCTTTCGTTCGTTCTTTTTCTGGCCATCTACCTGCTGGCGACGAACAACACGATGCGCCTGTCGCT
GTTTTTCCTGCTCGCCGCCTCGGGCTTCTTTCTCAAGGGCCGGAAAATTGGCCGCCTGTGGCTGAGCGGCATCATTCTGG
CCATCGTCGCCGTCCATGCCTCGGGCCTTTTCGCGACCGGCTACTCAACGCTGGATATCGCCACGACCTGCGTGTACCTG
ATCGCCTTGTTCTTCATTTTTGAAAACTACGAATCGTTCAAGGAAAAGGAACGCGAACGCAAGCAGTCCGAAGAAGAAGC
CCTACGGGCCAAGGAAATCGCCGAGGCCGAGAATCAAGCCAAGAGCCGCTTCCTGACCACCATGTCGCACGAAATCCGAA
CGCCGATGAACGGCATTCTCGGCATGGCGCAGCTGATGCTGGTTTCCAGGCTAACAGAGCAGGAACAGCACGATCACGCG
AGGACGATACTCAACTCCGGCCAGAGCCTGCTGGCACTGCTCAACGACATCCTCGACTTCTCCAAGATCGAAGCCGGCAA
GCTGGAACTGACGCCGGCCGTTTTCTCCCCCCGGCAAATCGTCGACGAAGCTGCCACGCTGTTTGCCGAATCGGCAAAAG
CCAAAGGGCTCGTGATCGAGGCAGTTTGGCATGGCCCCATCGACCAGCGTTATCTGGCCGACCCGATGCGCCTGCGCCAG
ATGCTCGCCAACCTGATCAACAATTCGATCAAATTTACCGGCAGCGGCTTCGTCCGCATTGAAGGTCGCGAGATCGAGCC
CATGGCAGACGCCAGCCTGCTGGAATTTTCCGTCACCGACAGCGGCATCGGCATTCCACCGGAGAAACTCACCCTGTTGT
TCAGGCCATTCTCCCAGGCCGACAGCTCGACGACCCGTGAGTATGGCGGCAGCGGGCTGGGACTATCCATCGTCCACAAC
CTGGCCAAGCTGATGGGTGGCGATGCCGGTGTCGAAAGCGAACCTGGCAAGGGATCGCGTTTCTGGTTCCGGGTTCAGGC
GATTCAACAGACTGCCAATGTCGACAGCCGCAAGACGGCACGCACGACCAGCATCGAGGTTCCAGCCGAGGCGCCGACGT
TGGCAGGGCTTGTCCTGATCGTCGAGGACAACCCGGTCAACCGCAAGGTCGCCCAGGCCATGCTCGGCAAAATGGGCATC
CAGAGCAAGAGTGTCGACAACGGCCAGGAAGCGGTCGATGCCATTGCGCAGGGGATGCGCCCCAACCTCATTTTGATGGA
TTGCCAGATGCCGGTCATGGACGGTTTCGAAGCAACAACGCAGATTCGCCGCTGGGAAATGGCCAATGGCCAGCCGCGCC
TGCCGATCGTCGCCCTGACTGCCGGCGCCTTCGAAGAAGATCGCCAGAACTGTCTTGCCGCCGGTATGGATGATTTCCTG
ACCAAACCCGTCAATATGGCTGACCTGTCTGCAAGCATCAACCGCCTGCTCGGCAAGCCAACGTCGTAG

Upstream 100 bases:

>100_bases
CACACACCATCTGGAATGCGGGCTGTTGCTGACCCGGCGATAGCAGTACGATCCAGCATCCCTTTCCAGCGCTGACTGAT
TGACTTAAGCAGAACAGACC

Downstream 100 bases:

>100_bases
CCCTTTCCTTTTGCGCATCACTTTCGGAGATTCCCGTGCAATCCATCCTGATCATCATCCATGCCCCTCCCTACGGCAGC
GAACGTTGCCTGTCCGCACT

Product: response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 582; Mature: 582

Protein sequence:

>582_residues
MMPAPPQPIDRDVPLDEESTAKIGFLYSVFLLAGLVAFVMGFVRWQTSVAMGFVDFGFAGFNFGLLLYLRRNPQKVEIVS
TLSLSLSFVLFLAIYLLATNNTMRLSLFFLLAASGFFLKGRKIGRLWLSGIILAIVAVHASGLFATGYSTLDIATTCVYL
IALFFIFENYESFKEKERERKQSEEEALRAKEIAEAENQAKSRFLTTMSHEIRTPMNGILGMAQLMLVSRLTEQEQHDHA
RTILNSGQSLLALLNDILDFSKIEAGKLELTPAVFSPRQIVDEAATLFAESAKAKGLVIEAVWHGPIDQRYLADPMRLRQ
MLANLINNSIKFTGSGFVRIEGREIEPMADASLLEFSVTDSGIGIPPEKLTLLFRPFSQADSSTTREYGGSGLGLSIVHN
LAKLMGGDAGVESEPGKGSRFWFRVQAIQQTANVDSRKTARTTSIEVPAEAPTLAGLVLIVEDNPVNRKVAQAMLGKMGI
QSKSVDNGQEAVDAIAQGMRPNLILMDCQMPVMDGFEATTQIRRWEMANGQPRLPIVALTAGAFEEDRQNCLAAGMDDFL
TKPVNMADLSASINRLLGKPTS

Sequences:

>Translated_582_residues
MMPAPPQPIDRDVPLDEESTAKIGFLYSVFLLAGLVAFVMGFVRWQTSVAMGFVDFGFAGFNFGLLLYLRRNPQKVEIVS
TLSLSLSFVLFLAIYLLATNNTMRLSLFFLLAASGFFLKGRKIGRLWLSGIILAIVAVHASGLFATGYSTLDIATTCVYL
IALFFIFENYESFKEKERERKQSEEEALRAKEIAEAENQAKSRFLTTMSHEIRTPMNGILGMAQLMLVSRLTEQEQHDHA
RTILNSGQSLLALLNDILDFSKIEAGKLELTPAVFSPRQIVDEAATLFAESAKAKGLVIEAVWHGPIDQRYLADPMRLRQ
MLANLINNSIKFTGSGFVRIEGREIEPMADASLLEFSVTDSGIGIPPEKLTLLFRPFSQADSSTTREYGGSGLGLSIVHN
LAKLMGGDAGVESEPGKGSRFWFRVQAIQQTANVDSRKTARTTSIEVPAEAPTLAGLVLIVEDNPVNRKVAQAMLGKMGI
QSKSVDNGQEAVDAIAQGMRPNLILMDCQMPVMDGFEATTQIRRWEMANGQPRLPIVALTAGAFEEDRQNCLAAGMDDFL
TKPVNMADLSASINRLLGKPTS
>Mature_582_residues
MMPAPPQPIDRDVPLDEESTAKIGFLYSVFLLAGLVAFVMGFVRWQTSVAMGFVDFGFAGFNFGLLLYLRRNPQKVEIVS
TLSLSLSFVLFLAIYLLATNNTMRLSLFFLLAASGFFLKGRKIGRLWLSGIILAIVAVHASGLFATGYSTLDIATTCVYL
IALFFIFENYESFKEKERERKQSEEEALRAKEIAEAENQAKSRFLTTMSHEIRTPMNGILGMAQLMLVSRLTEQEQHDHA
RTILNSGQSLLALLNDILDFSKIEAGKLELTPAVFSPRQIVDEAATLFAESAKAKGLVIEAVWHGPIDQRYLADPMRLRQ
MLANLINNSIKFTGSGFVRIEGREIEPMADASLLEFSVTDSGIGIPPEKLTLLFRPFSQADSSTTREYGGSGLGLSIVHN
LAKLMGGDAGVESEPGKGSRFWFRVQAIQQTANVDSRKTARTTSIEVPAEAPTLAGLVLIVEDNPVNRKVAQAMLGKMGI
QSKSVDNGQEAVDAIAQGMRPNLILMDCQMPVMDGFEATTQIRRWEMANGQPRLPIVALTAGAFEEDRQNCLAAGMDDFL
TKPVNMADLSASINRLLGKPTS

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=391, Percent_Identity=35.2941176470588, Blast_Score=200, Evalue=2e-52,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=43.2203389830509, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1788713, Length=381, Percent_Identity=33.5958005249344, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87081816, Length=385, Percent_Identity=33.2467532467532, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI145693157, Length=247, Percent_Identity=38.0566801619433, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=31.1688311688312, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790436, Length=301, Percent_Identity=27.2425249169435, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=26.3157894736842, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=253, Percent_Identity=26.0869565217391, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=28.695652173913, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1790346, Length=226, Percent_Identity=26.9911504424779, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=26.4957264957265, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=213, Percent_Identity=25.8215962441315, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788279, Length=210, Percent_Identity=29.0476190476191, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323034, Length=139, Percent_Identity=39.568345323741, Blast_Score=84, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6322044, Length=117, Percent_Identity=41.025641025641, Blast_Score=80, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 63894; Mature: 63894

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPAPPQPIDRDVPLDEESTAKIGFLYSVFLLAGLVAFVMGFVRWQTSVAMGFVDFGFAG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FNFGLLLYLRRNPQKVEIVSTLSLSLSFVLFLAIYLLATNNTMRLSLFFLLAASGFFLKG
HCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEC
RKIGRLWLSGIILAIVAVHASGLFATGYSTLDIATTCVYLIALFFIFENYESFKEKERER
CHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQSEEEALRAKEIAEAENQAKSRFLTTMSHEIRTPMNGILGMAQLMLVSRLTEQEQHDHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RTILNSGQSLLALLNDILDFSKIEAGKLELTPAVFSPRQIVDEAATLFAESAKAKGLVIE
HHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
AVWHGPIDQRYLADPMRLRQMLANLINNSIKFTGSGFVRIEGREIEPMADASLLEFSVTD
EEECCCCCHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCEEEEEECC
SGIGIPPEKLTLLFRPFSQADSSTTREYGGSGLGLSIVHNLAKLMGGDAGVESEPGKGSR
CCCCCCHHHHEEEECCHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCE
FWFRVQAIQQTANVDSRKTARTTSIEVPAEAPTLAGLVLIVEDNPVNRKVAQAMLGKMGI
EEEEHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCC
QSKSVDNGQEAVDAIAQGMRPNLILMDCQMPVMDGFEATTQIRRWEMANGQPRLPIVALT
CCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHCCHHHHHHHHHHHCCCCCCCCEEEEEE
AGAFEEDRQNCLAAGMDDFLTKPVNMADLSASINRLLGKPTS
CCCCHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMPAPPQPIDRDVPLDEESTAKIGFLYSVFLLAGLVAFVMGFVRWQTSVAMGFVDFGFAG
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
FNFGLLLYLRRNPQKVEIVSTLSLSLSFVLFLAIYLLATNNTMRLSLFFLLAASGFFLKG
HCCEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEC
RKIGRLWLSGIILAIVAVHASGLFATGYSTLDIATTCVYLIALFFIFENYESFKEKERER
CHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQSEEEALRAKEIAEAENQAKSRFLTTMSHEIRTPMNGILGMAQLMLVSRLTEQEQHDHA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RTILNSGQSLLALLNDILDFSKIEAGKLELTPAVFSPRQIVDEAATLFAESAKAKGLVIE
HHHHHCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
AVWHGPIDQRYLADPMRLRQMLANLINNSIKFTGSGFVRIEGREIEPMADASLLEFSVTD
EEECCCCCHHHHCCHHHHHHHHHHHHCCCEEEECCCEEEEECCCCCCCCCCCEEEEEECC
SGIGIPPEKLTLLFRPFSQADSSTTREYGGSGLGLSIVHNLAKLMGGDAGVESEPGKGSR
CCCCCCHHHHEEEECCHHHCCCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCE
FWFRVQAIQQTANVDSRKTARTTSIEVPAEAPTLAGLVLIVEDNPVNRKVAQAMLGKMGI
EEEEHHHHHHHHCCCCCCCCCCCEEECCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHCC
QSKSVDNGQEAVDAIAQGMRPNLILMDCQMPVMDGFEATTQIRRWEMANGQPRLPIVALT
CCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHCCHHHHHHHHHHHCCCCCCCCEEEEEE
AGAFEEDRQNCLAAGMDDFLTKPVNMADLSASINRLLGKPTS
CCCCHHHHHHHHHHCHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]