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The map label for this gene is fdoG [H]

Identifier: 71907447

GI number: 71907447

Start: 1953453

End: 1955915

Strand: Reverse

Name: fdoG [H]

Synonym: Daro_1818

Alternate gene names: 71907447

Gene position: 1955915-1953453 (Counterclockwise)

Preceding gene: 71907448

Following gene: 71907446

Centisome position: 43.45

GC content: 61.06

Gene sequence:

>2463_bases
GTGGCCAGTCTGGCTCCGACATTTGGCCGTGGCGCAATGACCAATCACTGGGTCGACATCAAGAATGCCGATGTCGTTTT
GGTGATGGGTGGCAACGCCGCAGAAGCACACCCGGTAGGATTCAAGTGGGTTATTGAAGCGAAGAAGCAGAACAAGGCAA
AACTCGTCGTTGTCGACCCGCGTTTCACGCGCTCGGCCTCGGTCGCCGACTTCTACGCGCCCATCCGTACCGGCACCGAC
ATCGCCTTCCTGGGCGGCGTCATCAATTACCTGTTGACCAACGACAAGATTCATCACGAATACGTCAAGGCCTACACCGA
CTTCAGTTTCCTGGTCGGCAACGACTATGCCTTCGACGACGGCATCTTCTCGGGCTACAACCCGGAGAAACGCAGCTACG
ACAAGGCCAGCTGGAACTACGTCAAGGGCGAGGACGGCTACGTCAAGACGGACCCGACGCTGCAGGATCCGCGTTGTGTC
TATCAACTGATGAAGCAGCACTACAGCCGCTACACGCCGGAAATGGTCGAGAAGATCTGCGGCACGCCGAAGGACGCCTT
CCTCAAGGTCGCCGAAATGATGGCCTCGACGGCGACCGGCGACCGAACGATGACCATCCTGTACGCGCTGGGCTGGACGC
AGCACTCGCAAGGCTCGCAGATGATCCGTACCGGTGCCATGGTGCAGATGCTGCTCGGCAACATCGGTGTCGCCGGCGGC
GGCATGAACGCGCTGCGCGGTCACTCCAACATCCAGGGCCTGACCGACCTCGGCCTGATGTCCAATCTGCTGCCGGGCTA
CATGACCCTGCCGGGCGAGAAGGAGACCGACTACGCGGCCTACATCGCCAAGCGGGCGCCCAAGCCGATGCGCCCCAACC
AGATGTCCTACTGGCAGAACTACGAGAAGTTCCACGTCAGTCTGATGAAGTCGTGGTTCGGTGACGCCGCGACCAAGGAG
AACAACTGGGGCTTCGACATGCTGCCCAAGCTGGACAAGGTGCATGACGTCCTGATGGTGATGGACGACATGTACCAGGG
CAAGATGAACGGCTACTTCTGCCAGGGCTTCAACCCGCTCGCCTCGTTCCCGAACAAGGCCAAGCTGGGCGCGGCGATGG
CCAAGCTCAAGTACATGGTCATCATCGACCCGCTGGCCACCGAGACTTCCGAATTCTGGAAGAACTACGGCGAGTACAAC
GACGTCGATCCGGCCAAGATCCAGACCACGGTCTTCCGCCTGCCTTCATCGTGTTTCGCCGAAGAAGACGGCTCGCTGGT
CAGCTCCAGCCGCCTGCTGCAATGGCACTGGAAGGGCGCCGAGCCCCCCGGCGAAGCGAAGACCGATCCGGCGATCATGG
CCGGCATCTTCATGAAGCTCAAGGCGATGTACAAGGAAAAGGGCGGCGCCTATCCGGATGCCATCCTCAACCTGACCTGG
GCCTACAAGGACCCGTACGAACCGTCACCGGAAGAAGTTGCCAAGGAGTACAACGGCAAGGCGCTGGTCGACCTCTACGA
CCCGAAGGACCCGACCAAGCTGATCCGCAAGGCCGGCGAACAGCTGGACAGCTTTGCCCTGTTGCGCGACGACGGCACGA
CGACCAGCGGTTGCTGGATCTTCAGCGGGGCATGGACGCAGGCCGGCAACAACATGGCACGGCGCGACAACAGCGATCCG
TGGGGCAACGGCCAGACCCTGAACTGGGCCTGGGCGTGGCCGGTCAATCGCCGCATCCTCTACAACCGCGCCTCCTGCGA
TCCGAGCGGCAAGCCGTTCAACCCGAAGCGCAAGCAGATCTGGTGGAATGGCACGGCGTGGACAGGCTCCGACATCCCCG
ATTTCAAGGCGGATTCGAACCCGGCCGACGGCATGGGGCCATTCATCATGAACCCGGAGGGGATCGCCCGCTTCTTCGCC
CGCGAAATGATGGCGGAAGGACCGTTCCCGGAGCACTACGAGCCGTTCGAAACGCCGATCGGCACCAACCCGATGAACAA
GAATCCCAAGGCCATCAGCAATCCGGCCGCCCGGGTGTTCAAGGGGGACATGGAAGTCTTCGGCACAGCCAAGGACTTCC
CGTATGCCGCGACGACCTATCGCCTGACCGAGCATTTCCACTACTGGACCAAGCACGCCAAGATCAACGCGATCCTGCAG
CCGGAACAGTTCGTGGAAATCGGCGAGGAACTGGCGAAGGAGAAGGGCATCGCCAGTGGCGACAAGGTCAAGGTGCGCTC
CAACCGGGGCTTCATCAAGGCCGTGGCGGTGGTCACCAAGCGCATCAAGGGGCTCAATGTGAACGGACAGAAAGTTCACC
ACGTCGGCATCCCCATCCACTGGGGATTCAAGGGCGTGGCGCGGATGGGCTTCCTGTCCAACACCCTGACGCCCTTCGTC
GGTGACGCGAACTCGCAAACACCGGAGTTCAAGTCCTTCCTCGTCAACATCGAGAAGATCTAA

Upstream 100 bases:

>100_bases
CGCCTCCAGCAACGAATCGGGATACATCACCCACAAGGTCGTTCGGTCGACCGGGATGATTGCCTTCGACAATCAGGCGC
GTGTTTGACACGGTCCGACG

Downstream 100 bases:

>100_bases
GGAGAGCTGCCATGGCACTGCAATCGCTAGACATCAAACAGCGCTCCGCGACGACGACACCCTCGACGCAGGCACGCCAG
ACCATCGAGATCGCCAAGTT

Product: formate dehydrogenase alpha subunit

Products: NA

Alternate protein names: Aerobic formate dehydrogenase major subunit; FDH-Z subunit alpha; Formate dehydrogenase-O subunit alpha [H]

Number of amino acids: Translated: 820; Mature: 819

Protein sequence:

>820_residues
MASLAPTFGRGAMTNHWVDIKNADVVLVMGGNAAEAHPVGFKWVIEAKKQNKAKLVVVDPRFTRSASVADFYAPIRTGTD
IAFLGGVINYLLTNDKIHHEYVKAYTDFSFLVGNDYAFDDGIFSGYNPEKRSYDKASWNYVKGEDGYVKTDPTLQDPRCV
YQLMKQHYSRYTPEMVEKICGTPKDAFLKVAEMMASTATGDRTMTILYALGWTQHSQGSQMIRTGAMVQMLLGNIGVAGG
GMNALRGHSNIQGLTDLGLMSNLLPGYMTLPGEKETDYAAYIAKRAPKPMRPNQMSYWQNYEKFHVSLMKSWFGDAATKE
NNWGFDMLPKLDKVHDVLMVMDDMYQGKMNGYFCQGFNPLASFPNKAKLGAAMAKLKYMVIIDPLATETSEFWKNYGEYN
DVDPAKIQTTVFRLPSSCFAEEDGSLVSSSRLLQWHWKGAEPPGEAKTDPAIMAGIFMKLKAMYKEKGGAYPDAILNLTW
AYKDPYEPSPEEVAKEYNGKALVDLYDPKDPTKLIRKAGEQLDSFALLRDDGTTTSGCWIFSGAWTQAGNNMARRDNSDP
WGNGQTLNWAWAWPVNRRILYNRASCDPSGKPFNPKRKQIWWNGTAWTGSDIPDFKADSNPADGMGPFIMNPEGIARFFA
REMMAEGPFPEHYEPFETPIGTNPMNKNPKAISNPAARVFKGDMEVFGTAKDFPYAATTYRLTEHFHYWTKHAKINAILQ
PEQFVEIGEELAKEKGIASGDKVKVRSNRGFIKAVAVVTKRIKGLNVNGQKVHHVGIPIHWGFKGVARMGFLSNTLTPFV
GDANSQTPEFKSFLVNIEKI

Sequences:

>Translated_820_residues
MASLAPTFGRGAMTNHWVDIKNADVVLVMGGNAAEAHPVGFKWVIEAKKQNKAKLVVVDPRFTRSASVADFYAPIRTGTD
IAFLGGVINYLLTNDKIHHEYVKAYTDFSFLVGNDYAFDDGIFSGYNPEKRSYDKASWNYVKGEDGYVKTDPTLQDPRCV
YQLMKQHYSRYTPEMVEKICGTPKDAFLKVAEMMASTATGDRTMTILYALGWTQHSQGSQMIRTGAMVQMLLGNIGVAGG
GMNALRGHSNIQGLTDLGLMSNLLPGYMTLPGEKETDYAAYIAKRAPKPMRPNQMSYWQNYEKFHVSLMKSWFGDAATKE
NNWGFDMLPKLDKVHDVLMVMDDMYQGKMNGYFCQGFNPLASFPNKAKLGAAMAKLKYMVIIDPLATETSEFWKNYGEYN
DVDPAKIQTTVFRLPSSCFAEEDGSLVSSSRLLQWHWKGAEPPGEAKTDPAIMAGIFMKLKAMYKEKGGAYPDAILNLTW
AYKDPYEPSPEEVAKEYNGKALVDLYDPKDPTKLIRKAGEQLDSFALLRDDGTTTSGCWIFSGAWTQAGNNMARRDNSDP
WGNGQTLNWAWAWPVNRRILYNRASCDPSGKPFNPKRKQIWWNGTAWTGSDIPDFKADSNPADGMGPFIMNPEGIARFFA
REMMAEGPFPEHYEPFETPIGTNPMNKNPKAISNPAARVFKGDMEVFGTAKDFPYAATTYRLTEHFHYWTKHAKINAILQ
PEQFVEIGEELAKEKGIASGDKVKVRSNRGFIKAVAVVTKRIKGLNVNGQKVHHVGIPIHWGFKGVARMGFLSNTLTPFV
GDANSQTPEFKSFLVNIEKI
>Mature_819_residues
ASLAPTFGRGAMTNHWVDIKNADVVLVMGGNAAEAHPVGFKWVIEAKKQNKAKLVVVDPRFTRSASVADFYAPIRTGTDI
AFLGGVINYLLTNDKIHHEYVKAYTDFSFLVGNDYAFDDGIFSGYNPEKRSYDKASWNYVKGEDGYVKTDPTLQDPRCVY
QLMKQHYSRYTPEMVEKICGTPKDAFLKVAEMMASTATGDRTMTILYALGWTQHSQGSQMIRTGAMVQMLLGNIGVAGGG
MNALRGHSNIQGLTDLGLMSNLLPGYMTLPGEKETDYAAYIAKRAPKPMRPNQMSYWQNYEKFHVSLMKSWFGDAATKEN
NWGFDMLPKLDKVHDVLMVMDDMYQGKMNGYFCQGFNPLASFPNKAKLGAAMAKLKYMVIIDPLATETSEFWKNYGEYND
VDPAKIQTTVFRLPSSCFAEEDGSLVSSSRLLQWHWKGAEPPGEAKTDPAIMAGIFMKLKAMYKEKGGAYPDAILNLTWA
YKDPYEPSPEEVAKEYNGKALVDLYDPKDPTKLIRKAGEQLDSFALLRDDGTTTSGCWIFSGAWTQAGNNMARRDNSDPW
GNGQTLNWAWAWPVNRRILYNRASCDPSGKPFNPKRKQIWWNGTAWTGSDIPDFKADSNPADGMGPFIMNPEGIARFFAR
EMMAEGPFPEHYEPFETPIGTNPMNKNPKAISNPAARVFKGDMEVFGTAKDFPYAATTYRLTEHFHYWTKHAKINAILQP
EQFVEIGEELAKEKGIASGDKVKVRSNRGFIKAVAVVTKRIKGLNVNGQKVHHVGIPIHWGFKGVARMGFLSNTLTPFVG
DANSQTPEFKSFLVNIEKI

Specific function: Allows to use formate as major electron donor during aerobic respiration. Subunit alpha possibly forms the active site [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI3868720, Length=820, Percent_Identity=66.8292682926829, Blast_Score=1178, Evalue=0.0,
Organism=Escherichia coli, GI3868719, Length=819, Percent_Identity=65.3235653235653, Blast_Score=1142, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=460, Percent_Identity=24.1304347826087, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI87081797, Length=249, Percent_Identity=25.7028112449799, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1787870, Length=234, Percent_Identity=25.6410256410256, Blast_Score=76, Evalue=1e-14,
Organism=Escherichia coli, GI171474008, Length=235, Percent_Identity=25.9574468085106, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1788534, Length=447, Percent_Identity=20.8053691275168, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006443
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: =1.2.1.2 [H]

Molecular weight: Translated: 91696; Mature: 91565

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLAPTFGRGAMTNHWVDIKNADVVLVMGGNAAEAHPVGFKWVIEAKKQNKAKLVVVDP
CCCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEECC
RFTRSASVADFYAPIRTGTDIAFLGGVINYLLTNDKIHHEYVKAYTDFSFLVGNDYAFDD
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCEECCC
GIFSGYNPEKRSYDKASWNYVKGEDGYVKTDPTLQDPRCVYQLMKQHYSRYTPEMVEKIC
CCCCCCCCCCCCCCCCCCCEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
GTPKDAFLKVAEMMASTATGDRTMTILYALGWTQHSQGSQMIRTGAMVQMLLGNIGVAGG
CCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GMNALRGHSNIQGLTDLGLMSNLLPGYMTLPGEKETDYAAYIAKRAPKPMRPNQMSYWQN
CCHHHCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
YEKFHVSLMKSWFGDAATKENNWGFDMLPKLDKVHDVLMVMDDMYQGKMNGYFCQGFNPL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHH
ASFPNKAKLGAAMAKLKYMVIIDPLATETSEFWKNYGEYNDVDPAKIQTTVFRLPSSCFA
HCCCCHHHHHHHHHHEEEEEEECCHHCCHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHC
EEDGSLVSSSRLLQWHWKGAEPPGEAKTDPAIMAGIFMKLKAMYKEKGGAYPDAILNLTW
CCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEE
AYKDPYEPSPEEVAKEYNGKALVDLYDPKDPTKLIRKAGEQLDSFALLRDDGTTTSGCWI
EECCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCEEE
FSGAWTQAGNNMARRDNSDPWGNGQTLNWAWAWPVNRRILYNRASCDPSGKPFNPKRKQI
EECCHHHCCCCHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEE
WWNGTAWTGSDIPDFKADSNPADGMGPFIMNPEGIARFFAREMMAEGPFPEHYEPFETPI
EECCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GTNPMNKNPKAISNPAARVFKGDMEVFGTAKDFPYAATTYRLTEHFHYWTKHAKINAILQ
CCCCCCCCCCCCCCCHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEC
PEQFVEIGEELAKEKGIASGDKVKVRSNRGFIKAVAVVTKRIKGLNVNGQKVHHVGIPIH
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCEEE
WGFKGVARMGFLSNTLTPFVGDANSQTPEFKSFLVNIEKI
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
ASLAPTFGRGAMTNHWVDIKNADVVLVMGGNAAEAHPVGFKWVIEAKKQNKAKLVVVDP
CCCCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEECC
RFTRSASVADFYAPIRTGTDIAFLGGVINYLLTNDKIHHEYVKAYTDFSFLVGNDYAFDD
CCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEECCCEECCC
GIFSGYNPEKRSYDKASWNYVKGEDGYVKTDPTLQDPRCVYQLMKQHYSRYTPEMVEKIC
CCCCCCCCCCCCCCCCCCCEEECCCCEEECCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH
GTPKDAFLKVAEMMASTATGDRTMTILYALGWTQHSQGSQMIRTGAMVQMLLGNIGVAGG
CCCHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
GMNALRGHSNIQGLTDLGLMSNLLPGYMTLPGEKETDYAAYIAKRAPKPMRPNQMSYWQN
CCHHHCCCCCCCCHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHCCCCCCCCHHHHHHH
YEKFHVSLMKSWFGDAATKENNWGFDMLPKLDKVHDVLMVMDDMYQGKMNGYFCQGFNPL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCCHH
ASFPNKAKLGAAMAKLKYMVIIDPLATETSEFWKNYGEYNDVDPAKIQTTVFRLPSSCFA
HCCCCHHHHHHHHHHEEEEEEECCHHCCHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHC
EEDGSLVSSSRLLQWHWKGAEPPGEAKTDPAIMAGIFMKLKAMYKEKGGAYPDAILNLTW
CCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHEEEEE
AYKDPYEPSPEEVAKEYNGKALVDLYDPKDPTKLIRKAGEQLDSFALLRDDGTTTSGCWI
EECCCCCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHEEEEECCCCCCCCEEE
FSGAWTQAGNNMARRDNSDPWGNGQTLNWAWAWPVNRRILYNRASCDPSGKPFNPKRKQI
EECCHHHCCCCHHHCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEE
WWNGTAWTGSDIPDFKADSNPADGMGPFIMNPEGIARFFAREMMAEGPFPEHYEPFETPI
EECCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
GTNPMNKNPKAISNPAARVFKGDMEVFGTAKDFPYAATTYRLTEHFHYWTKHAKINAILQ
CCCCCCCCCCCCCCCHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEC
PEQFVEIGEELAKEKGIASGDKVKVRSNRGFIKAVAVVTKRIKGLNVNGQKVHHVGIPIH
HHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCEEE
WGFKGVARMGFLSNTLTPFVGDANSQTPEFKSFLVNIEKI
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8346018; 9278503; 8522521 [H]