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The map label for this gene is regB [H]

Identifier: 71907218

GI number: 71907218

Start: 1703311

End: 1704570

Strand: Reverse

Name: regB [H]

Synonym: Daro_1586

Alternate gene names: 71907218

Gene position: 1704570-1703311 (Counterclockwise)

Preceding gene: 71907221

Following gene: 71907217

Centisome position: 37.87

GC content: 63.33

Gene sequence:

>1260_bases
ATGGCAACAACGCCCTGTACCAACGAAAACTCCGAGCATCTGGCCAACCTGCGTCGACTGGTCGCTGGCCGCTGGTTCGT
ACTCGCAGCCTTGACGCCACTGATCCTGCTCGCCCCGGGCCTGCTCGATATTCCGGTGCCACAGGTTCCCCTGCTCGGTA
TCGTTGCCATTACCGGGCTGTTCAACGCTTTTGCACAATGGCGGGTCAGCACGTCAAAAACCGCCAGCGCCTGCGAACTG
TTTGTTCAGTTACTTTTCGACATCGGGGCGCTGACCGCCATCGTTTTCTTCAGCGGTGGCGCTGCCAACCCGCTGGTTTC
AATGCTTCTGCCCCCCGTTGCCATCGCCGCCCTGACCCTGCCAGCGCGCTTTGCTGCCGTCGTCAGTGCCGTGGCGATCG
CCGCCTACTCGCTGCTGATGGTTTTTTACTTGCCACTGCCAATGCCGGATGCGACACGCGCCACCCGCCTGCACCTGATC
GGCATGTGGCTGATTTTTGTCCTTTCCGCCGCCATGATCGGCTGGATCATCATCCGCATGACCCGCCAGATTCGCCAACG
CGATGCCCAACTGGCGACTGCCCGCGAACAGGCTCTGCGCGACGAACGGGTCATGGCCATGGGCACCCTGGCGGCCGGCG
CCGCCCATGAGCTGGGCACACCGCTTGGCACGATGGCCCTGCTCGCCGGAGAACTGGCCAACGATCCCAGCCTGAGCGGA
CCGTCACGCGAAGACATCGTGCTGCTCCGCCAACAGATCGGAGTCTGCAAGGAAATCATCACTGGTCTGTCACGCCGTGC
CGGTGCCGAACGCCTGGAAAATGCTCCGCTCGAAGCGTCCAATCGCTGGCTGGACAGTCTGCGCCAGCGTTGGCATGCGG
CCCGCCCGCAGGCCAGCAGCCGCCTGATCATCGCCAGCGACGGTACGCCCCCCGAAATCCTTGCCGATCCACGGCTTGAG
CAGGCCATCCTCAACCTGCTCAACAATGCAGCCAACGCCACGCCGAGTCCGCTGGAAGTCCGGCTTTCCTGGTGCACGGA
CAACCTGTGCATCGACATCCGTGACCACGGCCCCGGTTTCCCGCCAGAAGTTCTGGAACAGGGCGGGCAGACCAGTTTTC
CAGCCCATGAGCAAGGCAGCGGCGTCGGCCTGATACTGACCCGTAGCGCCATCGAACAACTCGGCGGCGCGCTGACCCTG
AGTAACCCTGAAGACGGCGGCGCCCTTGCCCGCATCGAACTGCCACGGATACAAGCATGA

Upstream 100 bases:

>100_bases
AGTAAGACCGCATGCAATAGATACTCCAAATAGCGCTGCGACGAATTGTCGCATCTCCCAAGCGACTGAAAATTGACTCA
AATCACGCATAATTCGCCCC

Downstream 100 bases:

>100_bases
ACGAAATGACGCTGATCATCGACGACGATCCTAGTTTCAATGCCATTCTGGTTCGCACCATGGAGCGGCGTGGCCACCCT
GCACGTGGTGCTCAGGATGC

Product: sensor histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MATTPCTNENSEHLANLRRLVAGRWFVLAALTPLILLAPGLLDIPVPQVPLLGIVAITGLFNAFAQWRVSTSKTASACEL
FVQLLFDIGALTAIVFFSGGAANPLVSMLLPPVAIAALTLPARFAAVVSAVAIAAYSLLMVFYLPLPMPDATRATRLHLI
GMWLIFVLSAAMIGWIIIRMTRQIRQRDAQLATAREQALRDERVMAMGTLAAGAAHELGTPLGTMALLAGELANDPSLSG
PSREDIVLLRQQIGVCKEIITGLSRRAGAERLENAPLEASNRWLDSLRQRWHAARPQASSRLIIASDGTPPEILADPRLE
QAILNLLNNAANATPSPLEVRLSWCTDNLCIDIRDHGPGFPPEVLEQGGQTSFPAHEQGSGVGLILTRSAIEQLGGALTL
SNPEDGGALARIELPRIQA

Sequences:

>Translated_419_residues
MATTPCTNENSEHLANLRRLVAGRWFVLAALTPLILLAPGLLDIPVPQVPLLGIVAITGLFNAFAQWRVSTSKTASACEL
FVQLLFDIGALTAIVFFSGGAANPLVSMLLPPVAIAALTLPARFAAVVSAVAIAAYSLLMVFYLPLPMPDATRATRLHLI
GMWLIFVLSAAMIGWIIIRMTRQIRQRDAQLATAREQALRDERVMAMGTLAAGAAHELGTPLGTMALLAGELANDPSLSG
PSREDIVLLRQQIGVCKEIITGLSRRAGAERLENAPLEASNRWLDSLRQRWHAARPQASSRLIIASDGTPPEILADPRLE
QAILNLLNNAANATPSPLEVRLSWCTDNLCIDIRDHGPGFPPEVLEQGGQTSFPAHEQGSGVGLILTRSAIEQLGGALTL
SNPEDGGALARIELPRIQA
>Mature_418_residues
ATTPCTNENSEHLANLRRLVAGRWFVLAALTPLILLAPGLLDIPVPQVPLLGIVAITGLFNAFAQWRVSTSKTASACELF
VQLLFDIGALTAIVFFSGGAANPLVSMLLPPVAIAALTLPARFAAVVSAVAIAAYSLLMVFYLPLPMPDATRATRLHLIG
MWLIFVLSAAMIGWIIIRMTRQIRQRDAQLATAREQALRDERVMAMGTLAAGAAHELGTPLGTMALLAGELANDPSLSGP
SREDIVLLRQQIGVCKEIITGLSRRAGAERLENAPLEASNRWLDSLRQRWHAARPQASSRLIIASDGTPPEILADPRLEQ
AILNLLNNAANATPSPLEVRLSWCTDNLCIDIRDHGPGFPPEVLEQGGQTSFPAHEQGSGVGLILTRSAIEQLGGALTLS
NPEDGGALARIELPRIQA

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=26.8722466960352, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44806; Mature: 44675

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTPCTNENSEHLANLRRLVAGRWFVLAALTPLILLAPGLLDIPVPQVPLLGIVAITGL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
FNAFAQWRVSTSKTASACELFVQLLFDIGALTAIVFFSGGAANPLVSMLLPPVAIAALTL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
PARFAAVVSAVAIAAYSLLMVFYLPLPMPDATRATRLHLIGMWLIFVLSAAMIGWIIIRM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRQIRQRDAQLATAREQALRDERVMAMGTLAAGAAHELGTPLGTMALLAGELANDPSLSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHCCCCCCCC
PSREDIVLLRQQIGVCKEIITGLSRRAGAERLENAPLEASNRWLDSLRQRWHAARPQASS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
RLIIASDGTPPEILADPRLEQAILNLLNNAANATPSPLEVRLSWCTDNLCIDIRDHGPGF
EEEEECCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEECCCCCC
PPEVLEQGGQTSFPAHEQGSGVGLILTRSAIEQLGGALTLSNPEDGGALARIELPRIQA
CHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCEEEECCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
ATTPCTNENSEHLANLRRLVAGRWFVLAALTPLILLAPGLLDIPVPQVPLLGIVAITGL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
FNAFAQWRVSTSKTASACELFVQLLFDIGALTAIVFFSGGAANPLVSMLLPPVAIAALTL
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
PARFAAVVSAVAIAAYSLLMVFYLPLPMPDATRATRLHLIGMWLIFVLSAAMIGWIIIRM
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRQIRQRDAQLATAREQALRDERVMAMGTLAAGAAHELGTPLGTMALLAGELANDPSLSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHHCCCCCCCC
PSREDIVLLRQQIGVCKEIITGLSRRAGAERLENAPLEASNRWLDSLRQRWHAARPQASS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCC
RLIIASDGTPPEILADPRLEQAILNLLNNAANATPSPLEVRLSWCTDNLCIDIRDHGPGF
EEEEECCCCCCHHHCCCHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEECCCCCC
PPEVLEQGGQTSFPAHEQGSGVGLILTRSAIEQLGGALTLSNPEDGGALARIELPRIQA
CHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCEEEECCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]