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The map label for this gene is actR [H]

Identifier: 71907217

GI number: 71907217

Start: 1702781

End: 1703314

Strand: Reverse

Name: actR [H]

Synonym: Daro_1585

Alternate gene names: 71907217

Gene position: 1703314-1702781 (Counterclockwise)

Preceding gene: 71907218

Following gene: 71907214

Centisome position: 37.84

GC content: 58.8

Gene sequence:

>534_bases
ATGAACGAAATGACGCTGATCATCGACGACGATCCTAGTTTCAATGCCATTCTGGTTCGCACCATGGAGCGGCGTGGCCA
CCCTGCACGTGGTGCTCAGGATGCAGCGTCCGCACTTGAGCTGGCCCGAGAAATTCGTCCGCTGCGCGTCGTCCTCGATC
TCAACCTGAATGGCAGTTCTGGCCTGGCCCTGATCCAGCCCCTGCTCGACATCAACCCGGATAGTCGTATTGTCGTCCTG
ACTGGCTACGCCAGCATCGCCACCGCAGTCGATGCCGTGAAACTGGGCGCCATTCAATATCTGGCCAAACCGGTCGAGAT
CGAAGCCATCCTGTCGGCCTTCGAGGACGATGGCGGTCCGGATTTCGACGTAGCGGCCTCGGATGAACCACTCTCGGTCG
ACCGTCTGGAGTGGGAACACATCCAACGCATCCTCAACGAAAACGATGGCAATATCTCGGCCACGGCCCGCGCCCTGAAA
ATGCACCGACGGACGCTTCAGCGCAAACTTTCGAAACGGCCGGTCAAGACATGA

Upstream 100 bases:

>100_bases
TGACCCGTAGCGCCATCGAACAACTCGGCGGCGCGCTGACCCTGAGTAACCCTGAAGACGGCGGCGCCCTTGCCCGCATC
GAACTGCCACGGATACAAGC

Downstream 100 bases:

>100_bases
AACCGGCAACAGTATTCGGCACAACCTAGTTCATCGCTTGCCAAAATGAAAAAAGCCCTGACGGAAGCAATATCAGTCAG
GGCTTTTTTGCAGACAAGCA

Product: helix-turn-helix, Fis-type

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MNEMTLIIDDDPSFNAILVRTMERRGHPARGAQDAASALELAREIRPLRVVLDLNLNGSSGLALIQPLLDINPDSRIVVL
TGYASIATAVDAVKLGAIQYLAKPVEIEAILSAFEDDGGPDFDVAASDEPLSVDRLEWEHIQRILNENDGNISATARALK
MHRRTLQRKLSKRPVKT

Sequences:

>Translated_177_residues
MNEMTLIIDDDPSFNAILVRTMERRGHPARGAQDAASALELAREIRPLRVVLDLNLNGSSGLALIQPLLDINPDSRIVVL
TGYASIATAVDAVKLGAIQYLAKPVEIEAILSAFEDDGGPDFDVAASDEPLSVDRLEWEHIQRILNENDGNISATARALK
MHRRTLQRKLSKRPVKT
>Mature_177_residues
MNEMTLIIDDDPSFNAILVRTMERRGHPARGAQDAASALELAREIRPLRVVLDLNLNGSSGLALIQPLLDINPDSRIVVL
TGYASIATAVDAVKLGAIQYLAKPVEIEAILSAFEDDGGPDFDVAASDEPLSVDRLEWEHIQRILNENDGNISATARALK
MHRRTLQRKLSKRPVKT

Specific function: Member of the two-component regulatory system ActS/ActR acting in acid tolerance. These data implicate that a two- component sensor may be involved in pH sensing and/or response [H]

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=110, Percent_Identity=31.8181818181818, Blast_Score=61, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 19430; Mature: 19430

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEMTLIIDDDPSFNAILVRTMERRGHPARGAQDAASALELAREIRPLRVVLDLNLNGSS
CCCEEEEECCCCCCCHHHEEEHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCC
GLALIQPLLDINPDSRIVVLTGYASIATAVDAVKLGAIQYLAKPVEIEAILSAFEDDGGP
CHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
DFDVAASDEPLSVDRLEWEHIQRILNENDGNISATARALKMHRRTLQRKLSKRPVKT
CCCCCCCCCCCCCHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNEMTLIIDDDPSFNAILVRTMERRGHPARGAQDAASALELAREIRPLRVVLDLNLNGSS
CCCEEEEECCCCCCCHHHEEEHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEEEECCCCCC
GLALIQPLLDINPDSRIVVLTGYASIATAVDAVKLGAIQYLAKPVEIEAILSAFEDDGGP
CHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
DFDVAASDEPLSVDRLEWEHIQRILNENDGNISATARALKMHRRTLQRKLSKRPVKT
CCCCCCCCCCCCCHHHCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]